The Latest Urogynaecology Journal Articles

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Keep up to date with the latest in urogynaecology. Check out the latest urogynaecology articles from leading medical journals in a single view, helping you discover relevant articles quickly and easily

  • Defining Mechanisms of Recurrence Following Apical Prolapse Repair Based on Imaging Criteria.
    Prolapse recurrence after transvaginal surgical repair is common; however, its mechanisms are ill-defined. A thorough understanding of how and why prolapse repairs fail is needed to address their high rate of anatomic recurrence and to develop novel therapies to overcome defined deficiencies.To identify mechanisms and contributors of anatomic recurrence after (1) vaginal hysterectomy with uterosacral […]
  • Sexual Function After Pelvic Organ Prolapse Surgery: A Systematic Review Comparing Different Approaches to Pelvic Floor Repair.
    Women consider preservation of sexual activity and improvement of sexual function as important goals following pelvic organ prolapse (POP) surgery. The aim of this systematic review is to compare sexual activity and function before and after prolapse surgery between specific approaches to POP surgery including native tissue (NT) repairs, transvaginal synthetic mesh (TVM), biologic grafts […]
  • Sentinel lymph node biopsy in high-grade endometrial cancer: a systematic review and meta-analysis of performance characteristics.
    Sentinel lymph node biopsy (SLNB) is widely accepted as the standard of care for surgical staging in low-grade endometrial cancer (EC), but its value in high-grade EC remains controversial. The aim of this systematic review and meta-analysis was to evaluate the performance characteristics of SLNB in EC patients with high-grade histology (PROSPERO CRD42020160280).We systematically searched […]
    Uterine artery embolization is an effective and safe technique for the treatment of uterine fibroids, but its use remains controversial for women who wish to procreate.To study the clinical, anatomical and obstetrical results of uterine artery embolization in patients of childbearing age not eligible for myomectomy.This was a retrospective cohort study of 398 female patients […]
  • The association between nocturia, hormonal symptoms and bladder parameters in women: an observational study.
    Post-menopausal nocturia is poorly understood. This study aimed to identify hormonal and lifestyle factors associated with nocturia and to understand the relative contribution of altered urine production and bladder storage dysfunction in women.Women ≥40 years presenting to public continence services were enrolled in a cross-sectional study. 153 participants completed a hormone status questionnaire, a validated […]
  • Anaemia in pregnancy remains a global health problem.
    In this issue of BJOG Hull et al…… et al report on an important study from South Africa regarding anaemia in pregnancy and the response to iron therapy. They report that in HIV-positive women the response was slower than in HIV-negative women. The underlying causes of anaemia varied and included iron deficiency (as assessed by […]
  • The Environment, Leiomyomas, Latinas, and Adiposity Study (ELLAS): Rationale and Design.
    Uterine leiomyomas, commonly known as fibroids, are benign tumors in postmenarchal females. By the age of 35, approximately 30% of females will have fibroids, and by age 50 the prevalence approaches 70% with some studies reporting >85% prevalence in African-American females. Prior studies evaluating the prevalence of fibroids have largely relied on self-reported fibroid diagnoses, […]
  • Surgical Management of Symptomatic Apical Pelvic Organ Prolapse: A Systematic Review and Meta-analysis.
    To systematically review objective and subjective success and complications of apical suspensions for symptomatic uterine or vaginal vault pelvic organ prolapse (POP).MEDLINE, CENTRAL,, and EMBASE (2002-2019) were searched using multiple terms for apical POP surgeries, including comparative studies in French and English.From 2,665 records, we included randomized controlled trials and comparative studies of interventions […]
  • Topical Imiquimod for the Treatment of High-Grade Squamous Intraepithelial Lesions of the Cervix: A Randomized Controlled Trial.
    To evaluate the histologic response rate of high-grade squamous intraepithelial lesions (HSIL) of the cervix after topical application of 5% imiquimod cream.In this phase II trial, women with cervical HSIL (cervical intraepithelial neoplasia [CIN] 2-3) were randomly assigned to 250 mg of 5% imiquimod cream applied to the cervix weekly for 12 weeks, followed by […]
  • Tamsulosin Versus Placebo to Prevent Postoperative Urinary Retention Following Female Pelvic Reconstructive Surgery: a Multicenter Randomized Controlled Trial.
    Postoperative urinary retention is common following female pelvic reconstructive surgery. Alpha receptor antagonists can improve dysfunctional voiding by relaxing the bladder outlet, and may be effective in reducing the risk of postoperative urinary retention.To determine whether tamsulosin is effective in preventing post-operative urinary retention in women undergoing surgery for pelvic organ prolapse.This was a multicenter, […]
  • Trends, characteristics, and outcomes of placenta accreta spectrum: A national study in the United States.
    Although an infrequent occurrence, the placenta can adhere abnormally to the gravid uterus leading to significantly high maternal morbidity and mortality during cesarean section (CS). Contemporary national statistics related to a morbidly adherent placenta, referred to as placenta accreta spectrum (PAS), are needed.To examine national trends, characteristics, and perioperative outcomes of women who underwent CS […]
  • Current Prescribing Practices and Guideline Concordance for the Treatment of Uncomplicated Urinary Tract Infections in Women.
    Uncomplicated urinary tract infections are one of the most common bacterial infections in the United States. Clinical practice guidelines from the Infectious Diseases Society of America recommend nitrofurantoin, trimethoprim-sulfamethoxazole and fosfomycin as first-line antibiotic treatments, and discourage the use of fluoroquinolone antibiotics. The United States Food and Drug Administration released several black box warnings about […]
  • Bladder Instillations With Triamcinolone Acetonide for Interstitial Cystitis-Bladder Pain Syndrome: A Randomized Controlled Trial.
    To evaluate the utility of adding triamcinolone acetonide to a standard bladder instillation solution for treatment of interstitial cystitis-bladder pain syndrome.This was a single-center, randomized, double-blind trial that compared symptom response in women with interstitial cystitis-bladder pain syndrome who underwent six bladder instillations with triamcinolone acetonide or six instillations without. All instillation solutions contained heparin, […]
  • Habitus and Pelvic Floor Symptoms and Support 1 Year Postpartum.
    To estimate the association between habitus measures and pelvic floor support and symptoms in primiparous women 1 year after term vaginal delivery.In this cross-sectional study including women enrolled at seven academic and community sites, we assessed pelvic floor support, weight, height, waist circumference, and percent fat using air displacement plethysmography and participants completed questionnaires, all […]
  • Caring for Patients Who Have Experienced Trauma: ACOG Committee Opinion Summary, Number 825.
    Trauma is experienced throughout the life span, and traumatic experiences may be remote events or current and ongoing. The health care community continues to learn the many ways in which trauma affects an individual’s health, relationships, utilization of the health care system, health care experience, and ability to adopt health-related recommendations. It is important for […]
  • Caring for Patients Who Have Experienced Trauma: ACOG Committee Opinion, Number 825.
    Trauma is experienced throughout the life span, and traumatic experiences may be remote events or current and ongoing. The health care community continues to learn the many ways in which trauma affects an individual’s health, relationships, utilization of the health care system, health care experience, and ability to adopt health-related recommendations. It is important for […]
  • The “rail sign”: An ultrasound finding in placenta accreta spectrum indicating deep villous invasion and adverse outcomes.
    Ultrasound has demonstrated a high accuracy in the prenatal diagnosis of placenta accreta spectrum (PAS). However, it is not known whether ultrasound findings can pinpoint the depths of villous invasion, recommend surgical strategies, and predict clinical outcomes.We describe an ultrasound descriptor for the placenta accreta spectrum and investigate whether it can predict the severity of […]
  • Falling in the margin.
    In a randomised controlled trial (RCT) we are usually trying to answer the question of which treatment is best. Sometimes, though, we may be considering a treatment that we do not believe will perform better than an existing option but has other benefits. For instance, it could be cheaper, easier to deliver or more acceptable […]
  • Prevalence and Trends in Urinary Incontinence Among Women in the United States 2005-2018.
    Women are disproportionally affected by urinary incontinence compared to men. Urinary incontinence results in physical and psychological adverse consequences and impaired quality of life and contributes to significant societal and economic burden. Previous studies reported high urinary incontinence burden in the US. However, the current prevalence and recent trends in urinary incontinence and its subtypes […]
  • Effect of sacrospinous hysteropexy with graft vs vaginal hysterectomy with uterosacral ligament suspension on treatment failure in women with uterovaginal prolapse: 5 year results of a randomized clinical trial.
    Vaginal hysterectomy with suture apical suspension is commonly performed for uterovaginal prolapse. Sacrospinous hysteropexy with graft (vaginal mesh hysteropexy) is an alternative, although in 2019 the FDA removed this mesh product from the U.S. market.Our objective was to compare the efficacy and adverse events of these two procedures.At 9 clinical sites in the U.S. NIH/NICHD […]
  • EVO100 Prevents Chlamydia and Gonorrhea in Women At High-Risk For Infection.
    According to the Centers for Disease Control and Prevention, rates of infection for Chlamydia trachomatis and Neisseria gonorrhea are increasing in the United States. EVO100 is an investigational antimicrobial, pH-modulating, vaginal gel with active ingredients L-lactic acid, citric acid, and potassium bitartrate that is being evaluated for the prevention of sexually transmitted infections.(s): The objectives […]
  • Recommended standardized anatomic terminology of the posterior female pelvis and vulva based on a structured medical literature review.
    Anatomic terminology in both written and verbal forms has been shown to be inaccurate and imprecise.We aimed to (1) review published anatomic terminology as it relates to the posterior female pelvis, posterior vagina, and vulva; (2) compare these terms to Terminologia Anatomica, the internationally standardized terminology, and (3) compile standardized anatomic terms for improved communication […]
  • Pregnancy Outcome In Homozygous Sickle Cell Disease: Observations From The Jamaican Birth Cohort.
    To document pregnancy outcome in homozygous sickle cell (SS) disease and in age-matched controls with a normal haemoglobin genotype followed from birth for up to 45 years.A total of 100,000 consecutive non-operative deliveries screened for sickle cell disease at the main Government maternity hospital in Kingston, Jamaica between 1973-1981 detected 311 (149 female) babies with […]
  • Association between postmenopausal vulvovaginal discomfort, vaginal microbiota and mucosal inflammation: Vaginal microbiome and treatment response in postmenopausal women.
    Half of all postmenopausal women report symptoms of vulvar, vaginal or urinary discomfort with significant impact on sexual function and quality of life; underlying mechanisms leading to symptoms are poorly understood. To examine the possibility that the vaginal microbiota and/or mucosal immune response contribute to the severity of bothersome vaginal symptoms we conducted a substudy […]
  • Urinary Incontinence, Body Mass Index, and Physical Activity in Young Women.
    Current evidence suggests that overweight and obesity are important risk factors for urinary incontinence in women. However, little is known about the relationships between body mass index (BMI), physical activity and urinary incontinence in women in their 20s.The aims were to: 1) compare prevalence rates of urinary incontinence and high BMI in two cohorts of […]
  • Prevalence of Urinary, Prolapse, and Bowel Symptoms in Mayer-Rokitansky-Küster-Hauser Syndrome.
    Müllerian agenesis, or Mayer-Rokitansky-Küster-Hauser syndrome, occurs in 1 in 4500-5000 individuals assigned female sex at birth. Pelvic floor symptoms among individuals with Mayer-Rokitansky-Küster-Hauser syndrome have not been well-studied and it is unknown how vaginal lengthening treatments affect these symptoms.To assess urinary, prolapse, and bowel symptoms in individuals with MRKH and to determine if symptoms vary […]
  • A Nationwide Population-based Survey on the Prevalence and Risk Factors of Symptomatic Pelvic Organ Prolapse in Adult Women in China – A Pelvic Organ Prolapse Quantification System-Based Study.
    To determine the prevalence, risk factors, and burden of symptomatic pelvic organ prolapse (POP) in adult Chinese women DESIGN: A nationwide cross-sectional study SETTING: Six geographic regions of mainland China PARTICIPANTS: Women aged ≥20 years old were included using a multistage, stratified, cluster sampling method from February 2014 through March 2016.We conducted a nationwide epidemiological […]
  • Brain death in pregnancy: a systematic review focusing on perinatal outcomes.
    Brain death (BD) during pregnancy might justify in select cases maternal somatic support to obtain fetal viability and maximize perinatal outcome.To evaluate by systematic review of literature all cases of BD during pregnancy with attempt at prolonging pregnancy with the aim of assessing perinatal outcomes.We performed a systematic review of the literature using Ovid Medline, […]
  • Incidental Findings at the Time of Cystoscopy: Clinical Updates in Women’s Health Care Primary and Preventive Care Review.
    Cystourethroscopy can be performed by obstetrician-gynecologists for diagnostic and occasional operative indications. Intraoperative use of cystourethroscopy to confirm urinary tract (urethral, bladder, and ureteral) integrity is one of the most important indications, because these findings can greatly affect patient care. This monograph provides an overview of appropriate instrumentation and technique for cystourethroscopy in women with […]
  • Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy.
    Uterine fibroids are a common cause of heavy menstrual bleeding and pain. Treatment with the combination of relugolix (an oral gonadotropin-releasing hormone-receptor antagonist), estradiol, and norethindrone acetate, administered once daily, may have efficacy in women with uterine fibroids and heavy bleeding while avoiding hypoestrogenic effects.We conducted two replicate international, double-blind, 24-week, phase 3 trials involving […]
    Induction of labor is one of the most common interventions in modern obstetrics and its frequency is expected to continue to increase. There is inconsistency as to how failed induction of labor is defined, however, the majority of studies, define success as the achievement of vaginal delivery. Induction of labor in nulliparous women poses an […]
  • Something Old, Something New & Something Borrowed.
    Surgical management of Placenta Accreta Spectrum (PAS) is, if anything, wrought with complexity. Placental invasion can be confined and relatively easy to manage or as surgically challenging as a Stage IV ovarian tumor. In the most extensive cases, the placenta is equally capable of encasing not only the ureter, but also the femoral vessels and […]
  • Long-term effectiveness and safety of open Burch colposuspension versus retropubic midurethral sling for stress urinary incontinence – results from a large comparative study.
    There are few adequately powered long-term trials comparing midurethral sling (MUS) and Burch colposuspension (BC). Recent concerns about synthetic mesh with new stringent clinical and research governance support the need for evidence to inform shared decision making.To compare long-term outcomes of open Burch colposuspension (BC) to the retropubic midurethral sling (RP-MUS).A matched cohort study of […]
  • Less-radical Surgery for Early Stage Cervical Cancer: A Systematic Review.
    A systematic review was performed to examine the outcomes of simple hysterectomy for women with low-risk, early-stage cervical cancer.MEDLINE, Embase, Web of Science, and were searched from inception until November 4, 2020.Original research reporting recurrence and/or survival outcomes among women with early stage (defined as IA2-IB1) cervical cancer who were treated with simple hysterectomy.Data […]
  • Preoperative Pelvic Floor Injections With Bupivacaine and Dexamethasone for Pain Control After Vaginal Prolapse Repair: A Randomized Controlled Trial.
    To test the hypothesis that preoperative pelvic floor muscle injections and pudendal nerve blocks with bupivacaine and dexamethasone would decrease postoperative pain after vaginal native tissue prolapse repairs, compared with saline and bupivacaine.We conducted a three-arm, double-blind, randomized trial of bilateral transobturator levator ani muscle injections and transvaginal pudendal nerve blocks before vaginal reconstructive and […]
  • Circulating Vascular Endothelial Growth Factor and Soluble fms-Like Tyrosine Kinase-1 as Biomarkers for Endometrial Remodeling Across the Menstrual Cycle.
    To characterize variation in circulating vascular endothelial growth factor (VEGF) and its receptor, soluble fms-like tyrosine kinase-1 (sFLT-1), across the menstrual cycle in normal ovulating women in relation to reproductive hormones to identify the utility of VEGF and sFLT-1 as peripheral biomarkers of endometrial remodeling.Ninety-six healthy, regularly menstruating ovulatory women, aged 18-44 years, enrolled in […]
  • Recreational Cannabis Use Before and After Legalization in Women With Pelvic Pain.
    To evaluate the prevalence and characteristics of recreational cannabis use in women with pelvic pain, and to examine the influence of cannabis legalization on these parameters.We conducted a retrospective analysis of a prospective registry of women with self-reported moderate-to-severe pelvic pain referred to a tertiary care clinic in Vancouver, Canada, 2013-2019. We excluded patients aged […]
  • Concurrent Retropubic Midurethral Sling and OnabotulinumtoxinA for Mixed Urinary Incontinence: A Randomized Controlled Trial.
    To evaluate whether retropubic midurethral sling combined with onabotulinumtoxinA is more effective than sling alone in improving mixed urinary incontinence symptoms.We conducted a prospective, double-blind, randomized, controlled trial of women with mixed urinary incontinence, planning to undergo midurethral sling. Women were randomly assigned to receive 100 unites of intradetrusor onabotulinumtoxinA or placebo during surgery. Participants […]
  • Constipation during and after pregnancy.
    Constipation during and after pregnancy is a neglected clinical problem. The association with pelvic floor disorders include both anal incontinence (Johannessen HH et al, BJOG, 2020, Vol 127(12):1499-1506) and urinary incontinence (Lian WQ et al, Int Urogynecol J. 2019 Oct;30(10):1629-1634.), and the major impact on quality of life and pregnancy experience, all justify more research […]
  • Pelvic Organ Prolapse after Three Modes of Hysterectomy: Long-Term Follow Up.
    There are various indications and approaches for hysterectomy; yet, the difference in long-term risk of subsequent prolapse after surgery is not well studied.To assess the risk of prolapse after abdominal, vaginal and laparoscopic/robotic hysterectomy for up to 17 years from surgery.A retrospective chart review study of women undergoing hysterectomy across all indications (benign and malignant) […]
  • When does fetal head rotation occur in spontaneous labor at term: results of an ultrasound-based longitudinal study in nulliparous women.
    Improved information about the evolution of fetal head rotation during labor is required. Ultrasound methods have the potential to provide reliable new knowledge about fetal head position.The aim of the study was to describe fetal head rotation in women in spontaneous labor at term using ultrasound longitudinally through the active phase.This was a single center, […]
  • Complications of Pelvic Organ Prolapse Surgery in the 2015 Finnish Pelvic Organ Prolapse Surgery Survey Study.
    To describe the major complications of pelvic organ prolapse (POP) surgery in Finland.The Finnish Pelvic Organ Prolapse Surgery Survey 2015 study is a prospective cohort of POP surgeries performed in Finland in 2015. Perioperative, postoperative, and late complications during 1 year of follow-up were compared among native tissue repair, transvaginal mesh, and abdominal mesh surgery. […]
  • Timing of diagnosis of complex lower urinary tract injury in the 30-day postoperative period following benign hysterectomy.
    Complex lower urinary tract injury (cLUTI) resulting from hysterectomy is a rare but highly morbid complication. While intraoperative recognition reduces risk of serious sequelae, observational studies have shown that the majority of cLUTI are recognized in the postoperative period. To date, limited research exists describing the timing of cLUTI diagnosis or risk factors associated with […]
  • Using the Novel Pelvic Organ Prolapse Histology Quantification System to Identify Phenotypes in Uterosacral Ligaments in Women with Pelvic Organ Prolapse.
    Pelvic organ prolapse is common, but the underlying etiologies are poorly understood which limits our current prevention and treatment options.Our primary objective was to compare uterosacral ligament histologic features in women with and without prolapse using the novel, Pelvic Organ Prolapse Histologic Quantification System. Our secondary aim was to determine if composite histologic findings in […]
  • Mind/Body (Hypnotherapy) Treatment of Women with Urgency Urinary Incontinence: Changes in Brain Attentional Networks.
    Prior study of patients with urgency urinary incontinence by functional magnetic resonance imaging showed altered function in areas of the brain associated with interoception and salience and with attention. Our randomized controlled trial of hypnotherapy for urgency urinary incontinence demonstrated marked improvement in urgency urinary incontinence symptoms at two months. A sub-sample of these urgency […]
  • Bacterial Vaginosis and Its Association with Infertility, Endometritis, and Pelvic Inflammatory Disease.
    Bacterial vaginosis (BV), pelvic inflammatory disease (PID), and endometritis are infections of the genital tract that can lead to many adverse health outcomes, including infertility. BV is characterized by a lower prevalence of lactobacilli and a higher prevalence of anaerobic bacteria, including Gardnerella vaginalis, Megasphaera spp., and Atopobium vaginae. Endometritis and PID are caused by […]
  • An evolution in sentinel node mapping for cervical cancer.
    The technique of sentinel lymph node (SLN) biopsy has emerged as an alternative to complete pelvic lymphadenectomy to establish lymph node status in early stage cervical cancers. Traditional lymph node stripping techniques are associated with high rates of patient morbidity, such as lymphedema. For the majority of patients who are free of lymph node metastases […]
  • Success and failure are dynamic, recurrent event states after surgical treatment for pelvic organ prolapse.
    The ideal measure of success after surgery for pelvic organ prolapse (POP) has long been debated. Historically, strict definitions based on anatomic perfection have dominated the literature. However, the importance of patient-centered perception of outcomes are equally or more important when comparing the success of various prolapse surgeries. Understanding the limitations of existing outcome definitions […]
  • The Gynecologic Exam of the Transfeminine Person Following Penile Inversion Vaginoplasty.
    As more transfeminine patients (transgender and gender diverse persons, sex assigned male at birth, who identify on the feminine spectrum of gender) are undergoing gender-affirming penile inversion vaginoplasty, gynecologists, as providers of vaginal care for both native and neovaginas, should be prepared to welcome these patients into their practice and offer long term pelvic health […]
  • A Framework Proposal for Quality and Safety Measurement in Gynecologic Emergency Care.
    To define and assess the prevalence of potentially life-threatening gynecologic emergencies among women presenting for acute pelvic pain for the purpose of developing measures to audit quality of care in emergency departments.We conducted a mixed-methods multicenter study at gynecologic emergency departments in France and Belgium. A modified Delphi procedure was first conducted in 2014 among […]
  • Primary Dysmenorrhea: Diagnosis and Therapy.
    Primary dysmenorrhea is defined as pain during the menstrual cycle in the absence of an identifiable cause. It is one of the most common causes of pelvic pain in women. Dysmenorrhea can negatively affect a woman’s quality of life and interfere with daily activities. The pathophysiology of primary dysmenorrhea is likely a result of the […]
  • Immediate Repair of a Complete Uterine Transection After Motor Vehicle Collision.
    Traumatic separation of the cervix from the uterine corpus is rare. We describe a case in which this injury was identified and surgically repaired at initial presentation to preserve fertility.An 18-year-old woman presented with a pelvic crush injury after a motor vehicle accident. Imaging revealed pelvic fractures and bladder rupture. Complete transection of the uterine […]
  • Risk Factors for Surgical Failure and Worsening Pelvic Floor Symptoms Within 5 Years After Vaginal Prolapse Repair.
    To assess independent risk factors for surgical failure and worsening pelvic floor symptoms within 5 years after vaginal prolapse surgery.This secondary analysis includes OPTIMAL (Operations and Pelvic Muscle Training in the Management of Apical Support Loss) (n=374) and E-OPTIMAL (Extended) (n=285) trial participants. Surgical failure was defined as apical descent greater than one third of […]
  • Changes in Sexual Activity and Function After Pelvic Organ Prolapse Surgery: A Systematic Review.
    We aimed to systematically review the literature to describe sexual activity and function before and after prolapse surgery.We searched MEDLINE, EMBASE, and databases from inception to April 2018.Prospective, comparative studies of reconstructive pelvic organ prolapse (POP) surgeries that reported sexual function outcomes were included. Studies were extracted for population characteristics, sexual function outcomes, and […]
  • Identification of Juvenile Cystic Adenomyoma Using High-Resolution Imaging.
    Juvenile cystic adenomyoma is a rare condition that is often misdiagnosed as a noncommunicating uterine horn or adnexal mass during adolescence.We describe two patients who presented with dysmenorrhea unresponsive to standard management with oral contraceptives. Both patients were initially misdiagnosed as having endometriotic cysts. Juvenile cystic adenomyoma was suspected on standard pelvic ultrasound scan and […]
  • Complement Activation and Regulation in Preeclampsia and HELLP Syndrome.
    The complement system is critical to human health due its central role in host defense and innate immunity. During pregnancy, the complement system must be appropriately regulated to allow for immunologic tolerance to the developing fetus and placenta. While some degree of complement activation can be seen in normal pregnancy, the fetus appears to be […]
  • Hydroxychloroquine early in Pregnancy and Risk of Birth Defects.
    Hydroxychloroquine (HCQ) is generally considered safe in pregnancy for the treatment of rheumatic conditions, but studies have been too small to evaluate teratogenicity. Quantifying the risk of congenital malformations associated with early pregnancy exposure to HCQ is important both in the context of its ongoing use for rheumatological disorders as well as its potential future […]
  • Role of carbon nanoparticle suspension in sentinel lymph node biopsy for early-stage cervical cancer: a prospective study.
    To evaluate the clinical diagnostic validity of carbon nanoparticle suspension (CNS) in sentinel lymph node biopsy (SLNB) for assessing lymphatic spread of early-stage cervical cancer.A prospective study.356 cases.We enrolled 356 stage Ia2-IIa2 cervical cancer patients to undergo SLNB using CNS, followed by systematic pelvic lymphadenectomy. All lymph node specimens were assessed using conventional histopathologic ± […]
  • Immediate Postoperative Pelvic Organ Prolapse Quantification Measures and 2-Year Risk of Prolapse Recurrence.
    To assess whether resting genital hiatus, perineal body, and total vaginal length measured intraoperatively at the conclusion of surgery are associated with prolapse recurrence 2 years after native tissue pelvic organ prolapse reconstruction.This ancillary analysis of the OPTIMAL (Operations and Pelvic Muscle Training in the Management of Apical Support Loss) trial included women who had […]
  • Cochrane Review Summaries-October 2020.
    With the current issue, the journal continues to bring new insights from Cochrane Systematic Reviews to the readers of Obstetrics & Gynecology. This month, we focus on potential interventions to improve pregnancy outcomes for women with recurrent pregnancy loss and antiphospholipid antibodies, the utility of pelvic floor muscle training in the perinatal period to prevent […]