The Latest Upper GI Surgery Journal Articles

Keep up to date with the latest in upper GI surgery. Check out the latest upper GI surgery articles from leading medical journals in a single view, helping you discover relevant articles quickly and easily

• Association of Frailty and Sex With Wait List Mortality in Liver Transplant Candidates in the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.30th December 2020
  Female liver transplant candidates experience higher rates of wait list mortality than male candidates. Frailty is a critical determinant of mortality in patients with cirrhosis, but how frailty differs between women and men is unknown.To determine whether frailty is associated with the gap between women and men in mortality among patients with cirrhosis awaiting liver […]
• The Covid-19 Pandemic: Lessons Learned for Sustained Trauma Preparedness and Responses.30th December 2020
  The emergence of coronavirus disease 2019 (COVID-19) that is caused by the SARS-CoV-2 virus has led to an overwhelming strain on healthcare delivery. This pandemic has created a sustained stress on the modern healthcare system, with unforeseen and potential drastic effects. Although the initial focus during this pandemic has been preparedness and response directed to […]
• Long-Term Survival After Minimally Invasive Versus Open Esophagectomy for Esophageal Cancer: A Nationwide Propensity-Score Matched Analysis.30th December 2020
  This study aimed to compare long-term survival following minimally invasive esophagectomy (MIE) versus open esophagectomy (OE) for esophageal cancer using a nationwide propensity-score matched cohort.MIE provides lower postoperative morbidity and mortality, and similar short-term oncological quality compared to OE.Data was acquired from the Dutch Upper Gastrointestinal Cancer Audit. Patients undergoing minimally invasive or open, transthoracic […]
• RAS/TP53 co-Mutation is Associated with Worse Survival after Concurrent Resection of Colorectal Liver Metastases and Extrahepatic Disease.22nd December 2020
  To determine if tumor genetics are associated with overall survival (OS) after concurrent resection of colorectal liver metastases (CLM) and extrahepatic disease (EHD).The prognosis for patients who undergo concurrent resection of CLM/EHD is unclear and the impact of somatic mutations has not been reported.Patients undergoing concurrent resection of CLM and EHD from 2007-2017 were identified […]
• Improved Preoperative Risk-Assessment Tools Are Needed to Guide Informed Decision-Making Before Esophagectomy.22nd December 2020
  We sought to evaluate the performance of two commonly used prediction models for postoperative morbidity in patients undergoing open and minimally invasive esophagectomy.Patients undergoing esophagectomy have a high risk of postoperative complications. Accurate risk assessment in this cohort is important for informed decision-making.We identified patients who underwent esophagectomy between January 2016 and June 2018 from […]
• Consensus Guidelines for the Use of Fluorescence Imaging in Hepatobiliary Surgery.22nd December 2020
  To establish consensus recommendations for the use of fluorescence imaging with indocyanine green (ICG) in hepatobiliary surgery.ICG fluorescence imaging has gained popularity in hepatobiliary surgery in recent years. However, there is varied evidence on the use, dosage, and timing of administration of ICG in clinical practice. To standardize the use of this imaging modality in […]
• Is Initial Board Certification Associated with Better Early-Career Surgical Outcomes?22nd December 2020
  To determine if initial American Board of Surgery certification in general surgery is associated with better risk-adjusted patient outcomes for Medicare patients undergoing partial colectomy by an early career surgeon.Board certification is a voluntary commitment to professionalism, continued learning and delivery of high-quality patient care. Not all surgeons are certified, and some have questioned the […]
• Preoperative Single-Dose Methylprednisolone Prevents Surgical Site Infections After Major Liver Resection: A Randomized Controlled Trial.22nd December 2020
  The primary aim of this study was to evaluate the efficacy of a single preoperative dose of methylprednisolone for preventing postoperative complications after major liver resections.Hepatic resections are associated with a significant acute systemic inflammatory response. This effect subsequently correlates with postoperative morbidity, mortality and length of recovery. Multiple small trials have proposed that the […]
• Expert Consensus Guidelines on Minimally Invasive Donor Hepatectomy for Living Donor Liver Transplantation From Innovation to Implementation: A Joint Initiative From the International Laparoscopic Liver Society (ILLS) and the Asian-Pacific Hepato-Pancreat17th December 2020
  The Expert Consensus Guidelines initiative on MIDH for LDLT was organized with the goal of safe implementation and development of these complex techniques with donor safety as the main priority.Following the development of minimally invasive liver surgery, techniques of MIDH were developed with the aim of reducing the short- and long-term consequences of the procedure […]
• Variations in colorectal cancer surgery practice across the United Kingdom during the COVID-19 pandemic – ‘Every land has its own law’.14th December 2020
  In March 2020 NHS England issued guidelines recognizing the elective component of cancer surgeries may be ‘curtailed’, due to staffing and supply shortages during the COVID-19 pandemic. However, it suggested, ‘local solutions’ should be sought in order to protect the delivery of cancer services. We aimed to compare surgeons’ practice for the provision of colorectal […]
• Challenges faced by orthopaedic trainees during the Covid-19 pandemic – An Irish perspective.11th December 2020
  The recent SARS-CoV2/COVID-19 pandemic has caused a change in most aspects of our daily lives. Our health systems have had to adjust at an unprecedented rate to accommodate care for patients affected by the virus. As a result there has been widespread disruption to trauma and elective services throughout the Orthopaedic community Worldwide. We discuss […]
• Variation in Surgical Spending Among the Highest Quality Hospitals for Cancer Surgery.20th November 2020
  This study evaluates the variation in spending by the highest-quality hospitals performing complex cancer surgery in the United States.As mortality rates for high-risk cancer surgery have improved, increased attention has focused on other elements of quality, such as complications. However, high-value surgical care requires both high-quality care and cost savings. Therefore, understanding any residual cost […]
• Randomized Trial of Laparoscopic Nissen vs. Anterior 180 Degree Partial Fundoplication – Late Clinical Outcomes at 15-20 years.20th November 2020
  To determine very late clinical outcomes at up to 20 years follow-up from a randomized controlled trial of Nissen vs. anterior 180-degree partial fundoplication.Nissen fundoplication for gastroesophageal reflux can be followed by troublesome side effects. To address this, partial fundoplications have been proposed. Previously reports from a randomized controlled trial of Nissen vs. anterior 180-degree […]
• Pathophysiological Mechanisms of GASTRO-ESOPHAGEAL Reflux Following Sleeve Gastrectomy.20th November 2020
  to evaluate the mechanisms associated with reflux events following sleeve gastrectomy (SG).Gastro-esophageal reflux (GERD) post-SG is a critical issue due to symptom severity, impact on quality of life, requirement for re-operation, and potential for Barrett’s esophagus. The pathophysiology is incompletely delineated.Post-SG patients, stratified into asymptomatic and symptomatic, underwent protocolized nuclear scintigraphy (n=83), 24-hour esophageal pH […]
• Can the Risk Analysis Index for Frailty Predict Morbidity and Mortality in Patients Undergoing High-Risk Surgery?20th November 2020
  To determine the effectiveness of the revised Risk Analysis Index (RAI-rev), administrative Risk Analysis Index (RAI-A), cancer-corrected Risk Analysis Index [RAI-rev (cancer-corrected)], and 5-variable modified Frailty Index (mFI-5) for predicting 30-day morbidity and mortality in patients undergoing high-risk surgery.There are several frailty composite measures, but none have been evaluated for predicting morbidity and mortality in […]
• Survival Following Trimodality Therapy in Patients With Locally Advanced Esophagogastric Adenocarcinoma: Does Only a Complete Pathologic Response Matter?20th November 2020
  To evaluate whether pCR exclusively defines major pathologic response to treatment with improved survival.pCR after trimodality therapy for EAC is infrequent but associated with improved prognosis. Yet most clinical trials and correlative studies designate pCR as the primary endpoint.We analyzed our prospectively maintained database for patients who underwent trimodality therapy for locally advanced esophageal adenocarcinoma […]
• Distinct Genomic Profiles are Associated With Conversion to Resection and Survival in Patients With Initially Unresectable Colorectal Liver Metastases Treated With Systemic and Hepatic Artery Chemotherapy.20th November 2020
  To examine genomic correlates of CTR and overall survival (OS) in patients with IU-CRLM treated with combination systemic and hepatic artery infusion (HAI) chemotherapy.In patients presenting with IU-CRLM, combination systemic and HAI chemotherapy enables CTR with associated long-term OS in a subset of patients. Genomic correlates of CTR and OS in IU-CRLM have not been […]
• Gastrectomy Versus Esophagectomy For Gastroesophageal Junction Tumors: Short- And Long-term Outcomes From the Dutch Upper GI Cancer Audit.20th November 2020
  Investigate long-term survival, morbidity, mortality and pathology results in patients following esophagectomy or total gastrectomy for GEJ cancer.Both a total gastrectomy and an esophagectomy may be valid treatment options in patients with gastroesophageal junction (GEJ) cancer. Which procedure results in the most optimal patient outcome is not well studied. The aim of this study was […]
• Association between Preoperative HbA1c Levels and Complications after Esophagectomy: Analysis of 15 801 Esophagectomies from the National Clinical Database in Japan.20th November 2020
  To elucidate the association between preoperative hemoglobin A1c (HbA1c) levels and short-term outcomes after oncologic esophagectomy.Although diabetes mellitus (DM) is associated with an increased risk of postoperative morbidity in several types of surgery, the association of DM with short-term outcomes after esophagectomy has shown conflicting results.We analyzed 15801 patients who underwent oncologic esophagectomy between 2015 […]
• Fetal Risk Stratification and Outcomes in Children with Prenatally Diagnosed Lung Malformations: Results from a Multi-Institutional Research Collaborative.20th November 2020
  To assess current clinical outcomes in children with prenatally diagnosed congenital lung malformations (CLMs) and to identify prenatal characteristics associated with adverse outcomes.Despite a wide spectrum of clinical disease, the identification of fetal CLM subgroups at increased risk for hydrops and respiratory compromise at delivery have not been well defined.A retrospective cohort study was conducted […]
• Preoperative Hepatic and Regional Arterial Chemotherapy in Patients Who Underwent Curative Colorectal Cancer Resection: A Prospective, Multi-Center, Randomized Controlled Trial.20th November 2020
  To evaluate the effects of the addition of preoperative hepatic and regional arterial chemotherapy (PHRAC) on prognosis of stage II and III colorectal cancer (CRC) in a multicenter setting.Our previous single-center pilot trial suggested that PHRAC in combination with surgical resection could reduce the occurrence of liver metastasis (LM) and improve survival in CRC patients.A […]
• Bariatric Surgery in Medicare Patients: Examining Safety and Healthcare Utilization in the Disabled and Elderly.20th November 2020
  To compare safety and healthcare utilization after sleeve gastrectomy versus Roux-en-Y gastric bypass in a national Medicare cohort.Though bariatric surgery is increasing among Medicare beneficiaries, no long-term, national studies examining comparative effectiveness between procedures exist. Bariatric outcomes are needed for shared decision-making and coverage policy concerns identified by the CMS Medicare Evidence Development and Coverage […]
• Evaluation of Patient Reported Gastroesophageal Reflux Severity at Baseline and at One-Year after Bariatric Surgery.20th November 2020
  To assess patient-reported gastroesophageal reflux disease (GERD) severity before and after sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB).Development of new-onset or worsening GERD symptoms following bariatric surgery varies by procedure, but there is a lack of patient-reported data to help guide decision-making.Retrospective cohort study of patients undergoing bariatric surgery in a statewide quality collaborative […]
• A More Extensive Lymphadenectomy Enhances Survival Following Neoadjuvant Chemoradiotherapy in Locally Advanced Esophageal Adenocarcinoma.17th November 2020
  We sought to determine the extent of lymphadenectomy that optimizes staging and survival in patients with locally advanced esophageal adenocarcinoma (EAC) treated with neoadjuvant chemoradiotherapy followed by esophagectomy.Several studies have found that a more extensive lymphadenectomy leads to better disease-specific survival in patients treated with surgery alone. Few studies, however, have investigated whether this association […]
• The Impact of Prehabilitation on Patient Outcomes in Hepatobiliary, Colorectal, and Upper Gastrointestinal Cancer Surgery: A PRISMA-Accordant Meta-Analysis.17th November 2020
  To determine the impact of prehabilitation on hospital length of stay, functional capacity, complications, and mortality after surgery in patients with hepatobiliary, colorectal, and upper gastrointestinal cancer.”Prehabilitation” encompasses exercise, nutrition, and psychosocial interventions to optimise health before surgery. The benefits of prehabilitation are ill-defined.Medline, Embase and Cochrane Databases were searched systematically for the terms “prehabilitation […]
• The Complexity of Defining Postoperative Pneumonia following Esophageal Cancer Surgery: A Spectrum of Lung Injury rather than a simple Infective complication?17th November 2020
  To analyze the spectrum of CDC-defined pneumonia following esophageal cancer surgery.Pneumonia is commonly documented following esophageal cancer surgery, and reducing its incidence is central to both ERAS development and to the evidence-base for minimally invasive approaches. The existing definitions of pneumonia based on hospital acquired pneumonia (HAP) classifications may be suboptimal in this context and […]
• An Implementation Assessment of the Virtual Acute Care for Elders Program From the Perspective of Key Stakeholders.17th November 2020
  The aim of this study was to obtain feedback from key stakeholders and end users to identify program strengths and weaknesses to plan for wider dissemination and implementation of the Virtual Acute Care for Elders (Virtual ACE) program, a novel intervention that improves outcomes for older surgical patients.Virtual ACE was developed to deliver evidence-based geriatric […]
• Outcomes of 350 Robotic-assisted Esophagectomies at a High-volume Cancer Center: A Contemporary Propensity-score Matched Analysis.17th November 2020
  To evaluate perioperative and oncologic outcomes in our RAMIE cohort and compare outcomes with contemporary OE controls.RAMIE has emerged as an alternative to traditional open or laparoscopic approaches. Described in all esophagectomy techniques, rapid adoption has been attributed to both enhanced visualization and technical dexterity.We retrospectively reviewed patients who underwent RAMIE for malignancy. Patient characteristics, […]
• Comparative Safety of Sleeve Gastrectomy and Gastric Bypass: An Instrumental Variables Approach.17th November 2020
  To compare the safety of sleeve gastrectomy and gastric bypass in a large cohort of commercially insured bariatric surgery patients from the IBM MarketScan claims database, while accounting for measurable and unmeasurable sources of selection bias in who is chosen for each operation.Sleeve gastrectomy has rapidly become the most common bariatric operation performed in the […]
• Hyperspectral Imaging (HSI) of Human Kidney Allografts.16th November 2020
  Aim of our study was to test a non-invasive Hyperspectral Imaging (HSI) technique as an intraoperative real time assessment tool for deceased donor kidney quality and function in human kidney allotransplantation.HSI is capable to deliver quantitative diagnostic information about tissue pathology, morphology and composition, based on the spectral characteristics of the investigated tissue. Since tools […]
• Artificial Intelligence for Intraoperative Guidance: Using Semantic Segmentation to Identify Surgical Anatomy During Laparoscopic Cholecystectomy.16th November 2020
  To develop and evaluate the performance of artificial intelligence (AI) models that can identify safe and dangerous zones of dissection, and anatomical landmarks during laparoscopic cholecystectomy (LC).Many adverse events during surgery occur due to errors in visual perception and judgment leading to misinterpretation of anatomy. Deep learning, a subfield of AI, can potentially be used […]
• Short-term outcomes after Ivor Lewis oesophagectomy for cancer during the COVID-19 pandemic.12th November 2020
  Elective surgery in the UK came to a halt during the early part of the COVID-19 pandemic. As COVID-19-related infection and mortality rates in Devon and Cornwall were relatively low, however, urgent elective surgery continued in Plymouth, with the necessary precautions in place. This study aimed to assess outcomes following Ivor Lewis oesophagectomy (ILO) during […]
• Worldwide Techniques and Outcomes in Robot-Assisted Minimally Invasive Esophagectomy (RAMIE): Results from the Multicenter International Registry.12th November 2020
  This international multicenter study by the Upper GI International Robotic Association (UGIRA) aimed to gain insight in current techniques and outcomes of RAMIE worldwide.Current evidence for RAMIE originates from single-center studies, which may not be generalizable to the international multicenter experience.20 centers from Europe, Asia, North-America, and South-America participated from 2016- 2019. Main endpoints included […]
• The use of the independent sector in providing NHS services during the Covid-19 outbreak; two hospitals experience.11th November 2020
  This paper reviews the activity undertaken between a teaching hospital and its adjacent Independent Hospital and its implementation under the Independent Sector Provider Contract between NHSE and the Independent Sector. RESULTS: From the instigation of the NHSE contract with the Independent Sector up until 28th June 2020 The Norfolk and Norwich University NHS Trust (NNUH) […]
• Improving the efficiency of ankle fracture care through home care and day-surgery units: Delivering safe surgery on a value-based healthcare model.7th November 2020
  Preoperative home care for suitable patients with ankle fractures is becoming an increasingly common practice. It allows adequate time for reduction of ankle swelling following a decision to undertake operative fixation has been made. We aim to assess the safety, efficiency, cost-effectiveness and differences in clinical & patient outcomes of day surgery unit (DSU) care […]
• Early Patient Discharge in Selected Patients is Not Associated with Higher Readmission After Major Abdominal Operations.6th November 2020
  Our objective was to examine the associations between early discharge and readmission after major abdominal operations.Advances in patient care resulted in earlier patient discharge after complex abdominal operations. Whether early discharge is associated with patient readmissions remains controversial.Patients who had colorectal, liver, and pancreas operations abstracted in 2011-2017 ACS NSQIP Participant Use Data Files were […]
• Anterior Approach vs Conventional Hepatectomy for Resection of Colorectal Liver Metastasis: A Randomized Clinical Trial.4th November 2020
  Tumor relapse after partial hepatectomy for colorectal liver metastasis (CRLM) remains an unsolved issue. Intraoperative manipulation of the liver during conventional hepatectomy might enhance hematogenous tumor cell spread. The anterior approach is an alternative approach that may reduce intraoperative tumor cell dissemination.To determine the efficacy and safety of the anterior approach compared with conventional hepatectomy […]
• Development and Validation of a Comprehensive Model to Estimate Early Allograft Failure Among Patients Requiring Early Liver Retransplant.28th October 2020
  Expansion of donor acceptance criteria for liver transplant increased the risk for early allograft failure (EAF), and although EAF prediction is pivotal to optimize transplant outcomes, there is no consensus on specific EAF indicators or timing to evaluate EAF. Recently, the Liver Graft Assessment Following Transplantation (L-GrAFT) algorithm, based on aspartate transaminase, bilirubin, platelet, and […]
• Comprehensive Molecular Characterization of Adenocarcinoma of the Gastroesophageal Junction Between Esophageal and Gastric Adenocarcinomas.21st October 2020
  To investigate the molecular characteristics of AGEJ compared with EAC and gastric adenocarcinoma.Classification of AGEJ based on differential molecular characteristics between EAC and gastric adenocarcinoma has been long-standing controversy but rarely conducted due to anatomical ambiguity and epidemiologic difference.The molecular classification model with Bayesian compound covariate predictor was developed based on differential mRNA expression of […]
• Magnetic Resonance Elastography Versus Transient Elastography in the Prediction of Complications After Resection for Hepatocellular Carcinoma.21st October 2020
  To compare the performances of magnetic resonance elastography (MRE) and transient elastography (TE) for predicting severe complications after hepatic resection (HR) in patients with hepatocellular carcinoma (HCC).Liver stiffness measurement (LSM) may have the potential to predict outcomes after HR in HCC patients.Consecutive patients who underwent HR for HCC between 2017 and 2019 were retrospectively enrolled. […]
• SRY is a Key Mediator of Sexual Dimorphism in Hepatic Ischemia/Reperfusion Injury.21st October 2020
  To identify the role and mechanism of a male specific gene, SRY, in I/R-induced hepatic injury.Males are more vulnerable to I/R injury than females. However, the mechanism of these sex-based differences remains poorly defined.Clinicopathologic data of patients who underwent hepatic resection were identified from an international multi-institutional database. Liver specific SRY TG mice were generated, […]
• Conditional Survival of Patients Who Underwent Curative Resection for Esophageal Squamous Cell Carcinoma.21st October 2020
  To analyze conditional survival estimates of patients with esophageal cancer who underwent curative resection.Conditional survival reflects dynamic prognosis updated to the current status and is a more relevant indicator for current healthcare and life decisions.This study included 1,883 patients who underwent complete resection for esophageal squamous cell carcinoma at a tertiary cancer center from 1994 […]
• Historical and Contemporary Management of Infantile Hepatic Hemangioma: A 30-year Single-center Experience.16th October 2020
  To describe outcome of infants with hemangioma(s) of the liver.Infantile hepatic hemangiomas exhibit a diverse phenotype. We report our 30-year experience and describe optimal management based on precise radiological classification.Retrospective review of 124 infants (66 female) 1986-2016. Categorical analysis with Chi and nonparametric comparison. Data expressed as median (range) and P < 0.05 considered significant.Lesions […]
• Transplant Oncology in Primary and Metastatic Liver Tumor: Principles, Evidence and Opportunities.16th October 2020
  : Transplant oncology defines any application of transplant medicine and surgery aimed at improving cancer patients’ survival and/or quality of life. In practice, liver transplantation for selected hepato-biliary cancers is the only solid organ transplant with demonstrated efficacy in curing cancer. Four are the proposed future contributions of transplant oncology in hepato-biliary cancer (4-e). 1. […]
• Multicenter Randomized Phase 2 Trial Comparing Chemoradiotherapy and Docetaxel Plus 5-Fluorouracil and Cisplatin (DCF) Chemotherapy as Initial Induction Therapy for Subsequent Conversion Surgery in Patients with Clinical T4b Esophageal Cancer: Short-term Results.16th October 2020
  We conducted a multicenter randomized prospective phase 2 trial of chemoradiotherapy (CRT) versus chemotherapy (CT) as initial induction therapy for conversion surgery (CS) in clinical T4b esophageal cancer. We compared treatment effects and adverse events.Although induction followed by CS is potentially curative for T4b esophageal cancer, the optimal initial induction treatment is unclear.Ninety-nine patients with […]
• Early Achievement of Enteral Nutrition Protein Goals by Intensive Care Unit Day 4 is Associated With Fewer Complications in Critically Injured Adults.15th October 2020
  : Objective: We hypothesized that failure to achieve protein goals early in the critical care course via enteral nutrition is associated with increased complications.Although robust randomized controlled trials are lacking, present data suggest that early, adequate nutrition is associated with improved outcomes in critically ill patients. Injured patients are at risk of accumulating significant protein […]
• Complementary Effect of Maternal Sildenafil and Fetal Tracheal Occlusion Improves Lung Development in the Rabbit Model of Congenital Diaphragmatic Hernia.15th October 2020
  To evaluate the effect of combining antenatal sildenafil with fetal tracheal occlusion (TO) in fetal rabbits with surgically induced congenital diaphragmatic hernia (CDH).Although antenatal sildenafil administration rescues vascular abnormalities in lungs of fetal rabbits with CDH, it only partially improves airway morphometry. We hypothesized that we could additionally stimulate lung growth by combining this medical […]
• Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.15th October 2020
  To elucidate the efficacy of adjuvant vaccine monotherapy using 3 Human Leukocyte Antigen (HLA)-A24-restricted tumor-specific peptide antigens for ESCC, upregulated lung cancer 10, cell division cycle associated 1, and KH domain-containing protein overexpressed in cancer 1.ESCC patients with pathologically positive nodes (pN(+)) have a high risk for postoperative recurrence, despite curative resection after preoperative therapy. […]
• Surgical Outcomes After Neoadjuvant Chemoradiation Followed by Curative Surgery in Patients With Esophageal Cancer: An Intergroup Phase lll Trial of the Swiss Group for Clinical Cancer Research (SAKK 75/08).15th October 2020
  To assess the impact of surgical technique in regard to morbidity and mortality after neoadjuvant treatment for esophageal cancer.The SAKK trial 75/08 was a multicenter phase III trial (NCT01107639) comparing induction chemotherapy followed by chemoradiation and surgery in patients with locally advanced esophageal cancer.Patients in the control arm received induction chemotherapy with cisplatin and docetaxel, […]
• Health-related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population-based cohort study.9th October 2020
  Minimally invasive oesophagectomy has been shown to reduce the risk of pulmonary complications compared with open oesophagectomy, but the effects on health-related quality of life (HRQoL) and oesophageal cancer survivorship remain unclear. The aim of this study was to assess the longitudinal effects of minimally invasive compared with open oesophagectomy for cancer on HRQoL.All patients […]
• Thoracoscopy or Thoracotomy for Esophageal Atresia: A Systematic Review and Meta-analysis.1st October 2020
  This systematic review with meta-analysis compares health- and provider-based outcomes of thoracoscopic to thoracotomy repair of esophageal atresia.Thoracoscopic surgery has become a routine operation for esophageal atresia repair. However, large studies comparing the safety and efficacy of thoracoscopy to thoracotomy are scarce. Current reviews are obscured with institutional experiences or pool small samples.PRISMA-compliant search in […]
• Indications for Total Gastrectomy in CDH1 Mutation Carriers and Outcomes of Risk-Reducing Minimally Invasive and Open Gastrectomies.30th September 2020
  CDH1 variants are increasingly identified on commercially available multigene panel tests, calling for data to inform counseling of individuals without a family history of gastric cancer.To assess association between CDH1 variant pathogenicity or family history of gastric or lobular breast cancer and identification of signet ring cell cancer and to describe outcomes of risk-reducing minimally […]
• Deep learning analysis of the primary tumour and the prediction of lymph node metastases in gastric cancer.29th September 2020
  Lymph node metastasis (LNM) in gastric cancer is a prognostic factor and has implications for the extent of lymph node dissection. The lymphatic drainage of the stomach involves multiple nodal stations with different risks of metastases. The aim of this study was to develop a deep learning system for predicting LNMs in multiple nodal stations […]
• Adjuvant therapy following oesophagectomy for adenocarcinoma in patients with a positive resection margin.29th September 2020
  The role of adjuvant therapy in patients with oesophagogastric adenocarcinoma treated by neoadjuvant chemotherapy is contentious. In UK practice, surgical resection margin status is often used to classify patients for receiving adjuvant treatment. The aim of this study was to assess the survival benefit of adjuvant therapy in patients with positive (R1) resection margins.Two prospectively […]
• Increase in Pediatric Perforated Appendicitis in the New York City Metropolitan Region at the Epicenter of the COVID-19 Outbreak.25th September 2020
  The aim of the study was to determine whether perforated appendicitis rates in children were influenced by the Coronavirus disease 2019 (COVID-19) surge.Disruption of care pathways during a public health crisis may prevent children from obtaining prompt assessment for surgical conditions. Progression of appendicitis to perforation is influenced by timeliness of presentation. In the context […]
• Symptomatic hepatothorax presenting 25 years after penetrating thoracoabdominal injury.24th September 2020
  Hepatic herniation through the diaphragm is a rare finding. It generally occurs due to a congenital diaphragmatic abnormality or blunt trauma resulting in a diaphragmatic defect. Making the diagnosis is difficult, as there are few definitive clinical signs and chest radiograph (CXR) findings may be non-specific. To our knowledge, only a single case report exists […]
• Enterocutaneous fistula from migration of hepatic artery infusion catheter.24th September 2020
  We present an 84-year-old man with erosion of the chemotherapy port on his chest wall. He had a history of colorectal cancer with liver metastases more than 20 years ago, when he underwent right hemicolectomy and liver resection. A hepatic artery infusion catheter was placed for targeted administration of chemotherapy for the liver metastases. Imaging […]
• Impact of targeted trainer feedback via video review on trainee performance of laparoscopic cholecystectomy.23rd September 2020
  Tools for improving operative performance for surgical trainees are increasingly desirable, particularly in the context of EWTD and ‘run-through’ training programmes. In addition, positive direct trainer feedback to trainees can improve skill acquisition and motivation, whilst negative feedback may have the opposite effect.1 We aimed to examine the impact of targeted trainer feedback based on […]
• Association of Sarcopenia and Body Composition With Short-term Outcomes After Liver Resection for Malignant Tumors.23rd September 2020
  Previous retrospective studies have shown that sarcopenia substantially alters the postoperative and oncological outcomes after liver resection for malignant tumors. However, the evidence is limited to small retrospective studies with heterogeneous results and the lack of standardized measurements of sarcopenia.To investigate the role of sarcopenia as a risk factor associated with 90-day morbidity after liver […]
• Smartphone-Based Assessment of Preoperative Decision Conflict and Postoperative Physical Activity Among Patients Undergoing Cancer Surgery: A Prospective Cohort Study.17th September 2020
  To determine the prevalence of clinically significant decision conflict (CSDC) among patients undergoing cancer surgery and associations with postoperative physical activity, as measured through smartphone accelerometer data.Patients with cancer face challenging treatment decisions, which may lead to CSDC. CSDC negatively affects patient-provider relationships, psychosocial functioning, and health-related quality of life; however, physical manifestations of CSDC […]