The Latest Thoracic Surgery Articles

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The latest thoracic surgery articles from leading medical journals.

  • Clinical implication of tumour spread through air spaces in pathological stage I lung adenocarcinoma treated with lobectomy.
    The aim of this study was to evaluate the clinical implication of tumour spread through air spaces (STAS) as a prognostic factor in pathological stage I lung adenocarcinoma treated with lobectomy and to identify related parameters.Medical records of patients who underwent pulmonary lobectomy for stage I (American Joint Committee on Cancers eighth edition) lung adenocarcinomas […]
  • Effect of a reduced donor heart right ventricular distensibility on post-heart transplant haemodynamics.
    This study aimed to investigate the characteristics of a reduced right ventricular distensibility after heart transplant.This study enrolled 64 adult patients who underwent heart transplant at our institution. The degree of right ventricular distensibility was quantified by calculating the difference between right atrial pressures (RAPs) of X descent and Y descent (X-Y) from the RAP […]
  • Medical malpractice litigations involving aortic dissection.
    Medical malpractice litigation arises when a discrepancy exists between a patient’s expectation of acceptable medical care and the care the patient receives. Aortic dissection is a frequently misdiagnosed and often-fatal condition. The purpose of this study was to characterize trends of medical malpractice litigations arising from aortic dissection, investigate the etiology, and analyze predictive factors […]
  • Expanded indications for lung transplantation for pulmonary complications after hematopoietic stem cell transplantation.
    Pulmonary complications after hematopoietic stem cell transplantation (HSCT) are associated with poor survival and can be treated by lung transplantation (LT). However, the indications for LT in patients with pulmonary complications after HSCT remain unclear due to low number of cases. HSCT is frequently conducted for hematologic malignancies, which have different recurrence patterns from solid-organ […]
  • Transcarotid versus transthoracic access for transcatheter aortic valve replacement: A propensity-matched analysis.
    Transcarotid access for transcatheter aortic valve replacement is emerging as an alternative to more traditional nonfemoral access options such as transapical or transaortic; however, comparative data are limited. The purpose of the study was to analyze outcomes after transcatheter aortic valve replacement using transcatheter compared with transthoracic (transapical/transaortic) access.The Society of Thoracic Surgeons/American College of […]
  • COVID-19: An Indian perspective.
    Lockdown, quarantine, self-isolation, personal protection equipment, and social distancing have become words of daily usage ever since the world health organization declared coronavirus disease 2019 (COVID-19) as a pandemic. The impact of COVID-19 extends over the medical field, economy, education, and politics. Though the knowledge of the virus is evolving, we are yet to find […]
  • Urgent transcatheter aortic valve replacement may be performed with acceptable long-term outcomes.
    The wide availability of transcatheter aortic valve replacement (TAVR) and broadening of its indications to most patients with aortic stenosis may increase its utilization in the urgent setting. However, a comparison of long-term outcomes of patients undergoing urgent TAVR when compared to elective TAVR have not been well studied.All patients that underwent TAVR from 2011 […]
  • Management of cardiovascular diseases in HIV/AIDS patients.
    Human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome, a pandemic in the current population causes severe weakness of the body’s immune system making the infected patient more vulnerable to life-threatening conditions. The disease predisposes the infected patient to several cardiovascular diseases and cerebrovascular diseases such as heart failure and stroke. The decline in CD4 cells following HIV […]
  • Transcatheter aortic valve implantation after branched thoracic endovascular aortic repair in zone 0.
    An 83-year-old woman who underwent emergent hemi-arch replacement for acute aortic dissection (Stanford Type A) and staged branched thoracic endovascular aortic repair in zone 0 was admitted for severe aortic stenosis. We performed transfemoral transcatheter aortic-valve implantation with an SAPIEN 3 valve. The interference between the stent frames of the valve and the stent grafts […]
  • Extensive repair of acute type A aortic dissection through a partial upper sternotomy and using complete stent-graft replacement of the arch.
    Partial upper sternotomy (mini-ER) can be used in some adult cardiac surgeries but is seldom performed in the treatment of acute type A aortic dissection (AAAD). This study aimed to assess the feasibility and short-term outcomes of complete stent-graft replacement of the arch with triple-branched stent graft for AAAD through a mini-ER.From 2015 to 2018, […]
  • Early septal reduction therapy for patients with obstructive hypertrophic cardiomyopathy.
    This study was conducted to determine the influence of early septal reduction therapy (SRT) after referral on survival in patients with obstructive hypertrophic cardiomyopathy.We reviewed the patients with obstructive hypertrophic cardiomyopathy (resting pressure gradient ≥30 mm Hg or provoked pressure gradient ≥50 mm Hg) who were evaluated at our clinic from 2000 to 2012. Early SRT was […]
  • Surgeons should be wise when choosing a material to repair heart defects.
    Various types of prosthetic materials are available for usage in cardiac surgery to repair heart defects. PTFE, Dacron, and bovine pericardial are some examples of the most used materials for this purpose. In this article, the authors describe the potential failure of the CorMatrix®. View the full article @ Journal of cardiac surgery Get PDF […]
  • Bicuspid aortic valve sparing root replacement.
    Mid and long-term data regarding the durability of bicuspid aortic valve sparing root replacement is not completely understood. In this study, our institutional experience is reviewed regarding this procedure with special attention to the operative technique.From 2004 to 2019, 1241 patients underwent aortic root replacement and of these 79 patients underwent bicuspid aortic valve sparing […]
  • Color Doppler ultrasound for surveillance following EVAR as the primary tool.
    As aneurysm-related events and rupture is not eliminated, postoperative lifelong surveillance is mandatory after endovascular aneurysm repair (EVAR). For surveillance colored Doppler ultrasound (CDUS) is a standard method of noninvasive evaluation having the advantages of availability, cost-effectiveness, and lack of nephrotoxicity and radiation. We evaluated CDUS for primary surveillance tool after elective EVAR by comparing […]
  • Management of aortic arch hypoplasia in neonates and infants.
    Surgical management of aortic arch hypoplasia (AAH) with associated intracardiac anomalies is a challenge in newborns. We reviewed the characteristics and outcomes of neonates and infants who underwent pulmonary artery banding concomitant to arch repair and single-stage total repair at our institution.Medical records of 60 patients undergoing aortic arch reconstruction for AAH from 2014 to […]
  • The changing landscape of percutaneous technology leading to surgical complications.
    With new technology comes new complications. We discuss the interesting case presented by Bjelic and colleagues regarding a misplaced TAVR (transcatheter aortic valve replacement) valve into the inflow cannula of a left ventricular assist device, leading to hemodynamic collapse. The author describes the pitfalls of the new technology and interesting surgical maneuvers to address these […]
  • Reoperation for Persistent or Recurrent Neurogenic Thoracic Outlet Syndrome.
    Identifying the exact cause for persistent and recurrent neurogenic thoracic outlet syndrome (NTOS) is challenging even with high-resolution imaging of the thoracic outlet. Improvement can be achieved with redo first rib resection, although the posterior first rib remnant is one of several potential points of brachial plexus compression. In approaching reoperative surgery for NTOS, the […]
  • Hypothermia for cardiogenic encephalopathy in neonates with dextro-transposition of the great arteries.
    Neonates with dextro-transposition of the great arteries (d-TGA) may experience rapid haemodynamic deterioration and profound hypoxaemia after birth. We report on d-TGA patients with severe acidosis, encephalopathy and their treatment with systemic hypothermia.This study is a single-centre retrospective cohort analysis of newborns with d-TGA.Ninety-five patients (gestational age ≥35 weeks) with d-TGA and intended arterial switch operation […]
  • Reduced left ventricular contractility, increased diastolic operant stiffness and high energetic expenditure in patients with severe aortic regurgitation without indication for surgery.
    Recent mortality studies showed worse prognosis in patients (ARNS) with severe aortic regurgitation and preserved ejection fraction (EF) not fulfilling the criteria of current guidelines for surgery. The aim of our study was to analyse left ventricular (LV) systolic and diastolic function and mechanical energetics to find haemodynamic explanations for the reduced prognosis of these […]
  • Surgical Technique: Minimally Invasive First-Rib Resection.
    Minimally invasive surgical approaches to the treatment of thoracic outlet syndrome (TOS) will become increasingly common as more surgeons gain experience in thoracoscopic and robotic technique. Robotic surgery may be more technically advantageous because of improved visualization and maneuverability of wristed instruments. Longer-term outcome data are necessary to definitively establish the equivalency or superiority of […]
  • Worse outcomes after conversion of thoracoscopic lobectomy for lung cancer.
    Conversion of thoracoscopic lobectomy for lung cancer to thoracotomy can adversely affect short-term outcomes, but the impact on long-term outcomes is unknown. This study aimed to identify the risk factors for conversion and to determine the influence of conversion on the outcomes of lung cancer treatment.This retrospective study included 1002 consecutive patients with lung cancer […]
  • Translocation of aberrant left subclavian artery and resection of Kommerell diverticulum during the concomitant repair of intracardiac anomalies.
    To assess the safety and efficacy of the translocation of the aberrant left subclavian artery (LSCA) and resection of the Kommerell diverticulum during the concomitant repair of intracardiac anomalies for paediatric patients who had a right-sided aortic arch.A retrospective review of paediatric patients who were diagnosed right-sided aortic arch, aberrant LSCA, Kommerell diverticulum and intracardiac […]
  • Surgical Technique: Supraclavicular First Rib Resection.
    Thoracic outlet syndrome is a condition of compression involving the brachial plexus and subclavian vessels. Although there are multiple surgical approaches to address thoracic outlet decompression, supraclavicular first rib resection with scalenectomy and brachial plexus neurolysis allow for complete exposure of the first rib, brachial plexus, and vasculature. This technique is described in detail. This […]
  • Structural valve deterioration after aortic valve replacement with the Trifecta valve.
    Despite promising short- and mid-term results for durability of the Trifecta valve, contradictory reports of early structural valve deterioration (SVD) do exist. We investigated the incidence of SVD after surgical aortic valve replacement (SAVR) with the Trifecta in our single-centre experience.Data of 347 consecutive patients (mean age 71.6 ± 9.5 years, 63.4% male) undergoing SAVR with the Trifecta […]
  • Midterm outcomes of endovascular treatment with bare metal stents for Leriche syndrome patients.
    This study was undertaken to evaluate the acute and midterm results of endovascular treatment with bare metal stents (BMS) for Leriche syndrome patients.Patients with Leriche syndrome treated with BMS from August 2008 to May 2017 were included in the study and followed up. The primary endpoints were primary restenosis-free survival rates at 1, 2 and […]
  • Physical Therapy Management of Neurogenic Thoracic Outlet Syndrome.
    Neurogenic thoracic outlet syndrome is a complex and challenging condition to manage. There is a lack of high-quality evidence to guide clinical decision making and therefore a need to individualize treatment. Examination includes identifying postural, anatomic, and biomechanical factors that contribute to compromise of the neurovascular structures. Patients can experience good outcomes with conservative management […]
  • Surgical treatment of pleural empyema in Coronavirus disease 19  patients: the Southern Switzerland experience.
    We report the first surgical series of patients developing pleural empyema after severe bilateral interstitial lung disease in confirmed severe acute respiratory syndrome coronavirus 2 infection. The empyema results in a complex medical challenge that requires combination of medical therapies, mechanical ventilation and surgery. The chest drainage approach was not successful to relieve the symptomatology […]
  • Adjunctive endovascular balloon fracture fenestration for chronic aortic dissection.
    Positive remodeling after thoracic endovascular aortic repair (TEVAR) for chronic thoracic aortic dissection is variable due to incomplete distal seal and retrograde false lumen perfusion. We assessed the outcomes of adjunctive balloon fracture fenestration (BFF) during TEVAR in patients with chronic aortic dissection complicated by negative remodeling.From June 2013 to January 2016, 49 patients with […]
  • Evaluation of Patients with Neurogenic Thoracic Outlet Syndrome.
    Neurogenic thoracic outlet syndrome (NTOS) results from the compression or irritation of the brachial plexus within the thoracic outlet. The associated symptoms result in significant disability and negative effects on patient health-related quality of life. The diagnosis of NTOS, despite being the most common type of TOS, remains challenging for surgeons, in part due to […]
  • Congenital left atrial appendage aneurysm with unexpected course of left anterior descending coronary artery.
    The left atrial appendage (LAA) aneurysm is a rare condition that can produce local compressive effects and complications including supraventricular tachyarrhythmias, thromboembolic events and myocardial ischaemia. We present a rare case of a neonate with a congenital LAA aneurysm which resulted in local compressive effects on the left ventricle, severe mitral regurgitation and malposition of […]
  • Priming protects the spinal cord in an experimental aortic occlusion model.
    Paraplegia is a devastating complication in aortic aneurysm surgery. Modifying the spinal cord vasculature is a promising method in spinal cord protection. The aim of this study was to assess whether the spinal cord can be primed by occluding thoracic segmental arteries before simulated aneurysm repair in a porcine model.Twelve piglets were randomly assigned to […]
  • Evaluation and Management of Arterial Thoracic Outlet Syndrome.
    Arterial thoracic outlet syndrome is rare and may be associated with a bony anomaly. Patient presentation can range from mild arm discoloration and claudication to severe limb-threatening ischemia. For patients with subclavian artery dilation without secondary complications, thoracic outlet decompression and arterial surveillance is sufficient. Patients with subclavian artery aneurysms or distal embolization require decompression […]
  • Repair of traumatic ventricular septal defect and left ventricular aneurysm after blunt chest trauma.
    Blunt chest trauma can cause a variety of cardiac injuries, either immediately or days after the trauma. We report a case of traumatic ventricular septal defect and ribbonlike left ventricular aneurysm, which was diagnosed 15 years after the initial blunt chest trauma. It was successfully repaired using the endoventricular patch technique with a satisfactory 1-year follow-up […]
  • Preoperative left atrial strain abnormalities are associated with the development of postoperative atrial fibrillation following isolated coronary artery bypass surgery.
    Postoperative atrial fibrillation (POAF) is a common complication after coronary artery bypass grafting (CABG). Currently, there is no reliable way to determine preoperatively which patients will develop POAF following CABG. The aim of this study was to determine whether preoperative left atrial (LA) strain analysis might identify patients destined to develop POAF following CABG.From 2016 […]
  • Evaluation and Management of Venous Thoracic Outlet Syndrome.
    Venous thoracic outlet syndrome (TOS) is uncommon but occurs in young, healthy patients, typically presenting as subclavian vein (SCV) effort thrombosis. Venous TOS arises through chronic repetitive compression injury of the SCV in the costoclavicular space with progressive venous scarring, focal stenosis, and eventual thrombosis. Diagnosis is evident on clinical presentation with sudden spontaneous upper […]
  • Exclusion of complex aortic aneurysm with chimney endovascular aortic repair is applicable in a minority of patients treated with fenestrated endografts.
    The Medtronic Endurant II stent graft has recently received Conformité Européenne (CE) approval for the use in chimney endovascular aortic repair (ChEVAR) for the treatment for juxtarenal aortic aneurysms. The aim of this study was to assess the percentage of patients treated by fenestrated endovascular repair who would have been alternatively suitable for the treatment […]
  • Cardiac surgery outcomes in patients with coronavirus disease 2019 (COVID-19): A case-series report.
    The impact of coronavirus disease 2019 (COVID-19) on the postoperative course of patients after cardiac surgery is unknown. We experienced a major severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in our cardiac surgery unit, with several patients who tested positive early after surgery. Here we describe the characteristics, postoperative course, and laboratory findings of […]
  • Imaging Assessment of Thoracic Outlet Syndrome.
    Imaging studies play a significant role in assessment of thoracic outlet syndrome. In this article, we discuss the etiology and definition of thoracic outlet syndrome and review the spectrum of imaging findings seen in patients with thoracic outlet syndrome. We then discuss an optimized technique for computed tomography and MRI of patients with thoracic outlet […]
  • Heart transplant outcomes in patients with mechanical circulatory support: cold storage versus normothermic perfusion organ preservation.
    Patients with mechanical circulatory support bridged to a heart transplant (HTx) are at higher risk of postoperative graft dysfunction. In this subset, a mode of graft preservation that shortens graft ischaemia should be beneficial.The outcomes of 38 patients on mechanical circulatory support (extracorporeal life support, left ventricular assist device and biventricular assist device) who received […]
  • Progression in Fontan conduit stenosis and hemodynamic impact during childhood and adolescence.
    To characterize changes in Fontan conduit size over time and determine if cross-sectional area (CSA) affects cardiac output, pulmonary artery growth, and exercise capacity.We conducted a retrospective cross-sectional study of patients with Fontan physiology who underwent cardiac magnetic resonance imaging or cardiac catheterization between January 2013 and October 2019. We collected Fontan and pulmonary artery […]
  • How Common Is Thoracic Outlet Syndrome?
    The incidence of neurogenic thoracic outlet syndrome is completely unknown, and has been wildly overestimated in the past. Based on a prospectively maintained database at our academic Thoracic Outlet Center, we estimate the yearly incidence of neurogenic and venous thoracic outlet syndrome to be approximately 3 and 1 per 100,000 population, respectively. The ratio of […]
  • Upside-down and kissing stent graft techniques for late extravasation of a prosthetic graft implanted in the abdominal aorta.
    Extravasation of prosthetic grafts is rare. Various anatomical problems after graft replacement might make standard endovascular treatment difficult. Use of a commercially available main body requires an adequate distance of the flow divider. An 86-year-old man developed extravasation of a graft that had been implanted in the infrarenal abdominal aorta 24 years previously. Endovascular repair […]
  • Anatomy and Embryology of the Thoracic Outlet.
    The thoracic outlet is the space between the thorax and axilla through which the subclavian vein, subclavian artery, and brachial plexus travel from their central origins to their peripheral termini. Its bounds include the clavicle, first thoracic rib, insertion of the pectoralis minor muscle onto the coracoid process of the humerus, and the sternum. It […]
  • The development of a flexible heart model for simulation-based training.
    Simulation-based training has shown to be effective in training new surgical skills. The objective of this study is to develop a flexible 3-dimensional (3D)-printed heart model that can serve as a foundation for the simulation of multiple cardiovascular procedures.Using a pre-existing digital heart model, 3D transoesophageal echocardiography scans and a thoracic CT scan, a full […]
  • Mitral valve surgery after a failed MitraClip procedure.
    Among patients undergoing transcatheter mitral valve repair with the MitraClip device, a relevant proportion (2-6%) requires open mitral valve surgery within 1 year after unsuccessful clip implantation. The goal of this review is to pool data from different reports to provide a comprehensive overview of mitral valve surgery outcomes after the MitraClip procedure and estimate in-hospital […]
  • Congenital atresia of the left main coronary artery: management of a 5-year-old child in extremis.
    Atresia of the left main coronary artery is a rare coronary anomaly. We describe the case of a 5-year-old child presenting in emergency in extremis. Clinical findings of haemodynamic collapse, malignant ventricular tachyarrhythmias and severe mitral regurgitation were indicative of a possible ischaemic aetiology. Surgical revascularization of the atretic left main coronary artery segment using […]
  • Bacterial colonization of explanted non-endocarditis cardiac valves: evidence and characterization of the valvular microbiome.
    Bacterial colonization has been already demonstrated in heart valve tissues of patients without cardiovascular infections. However, the evidence of a valvular microbiome is still scarce. The next-generation sequencing method was carried out on 34 specimens of aortic (n = 20) and mitral valves (n = 14) explanted from 34 patients having neither evidence nor history of infectious diseases, particularly […]
  • Benefits of robotically-assisted surgery for complex mitral valve repair.
    To determine whether robotic mitral valve repair can be applied to more complex lesions compared with minimally invasive direct mitral valve repair through a right thoracotomy.We enrolled 335 patients over a 9-year period; 95% of the robotic surgeries were performed after experience performing direct mitral valve repair.The mean age in the robotic versus thoracotomy repair […]
  • Associations between mean arterial pressure during cardiopulmonary bypass and biomarkers of cerebral injury in patients undergoing cardiac surgery: secondary results from a randomized controlled trial.
    Cardiac surgery is associated with risk of cerebral injury and mean arterial pressure (MAP) during cardiopulmonary bypass (CPB) is suggested to be associated with cerebral injury. The ‘Perfusion Pressure Cerebral Infarcts’ (PPCI) trial randomized patients undergoing coronary artery bypass grafting (CABG) and/or aortic valve replacement to a MAP of 40-50 or 70-80 mmHg during CPB and […]
  • Acute aortic dissection with entry tear at the aortic arch: long-term outcome.
    The goal was to evaluate outcomes after conservative or surgical treatment of acute aortic arch dissections.Between January 2009 and December 2018, patients with a diagnosis of acute aortic dissection were analysed. Aortic arch aortic dissection was defined as a dissection with an isolated entry tear at the aortic arch with no involvement of the ascending […]
  • Mid-term outcomes of coronary endarterectomy combined with coronary artery bypass grafting.
    The aim of this study was to evaluate the mid-term outcome of coronary endarterectomy (CE) combined with coronary artery bypass grafting (CABG) and explore the potential risk factors for adverse events.A total of 208 consecutive patients underwent CE between 2008 and 2018 in our centre, of which 198 were included in this retrospective cohort study. […]
  • Aortic valve neocuspidalization in paediatric patients with isolated aortic valve disease: early experience.
    There is growing interest in the aortic valve (AV) neocuspidalization technique for the treatment of aortic valve disease (AVD). We report our medium-term results with this procedure performed in a paediatric patient population.Between July 2016 and May 2020, 22 patients with both congenital and acquired isolated AVD were treated with neocuspidalization. The primary outcome was […]
  • Talc pleurodesis in malignant pleural effusion: a systematic review and meta-analysis.
    Malignant pleural effusion is a severe and common complication in patients with primary or metastatic malignancies of the pleura. Although talc pleurodesis is widely used for managing malignant pleural effusions, there is still controversy in the literature regarding its superiority compared to other approaches. We conducted this meta-analysis to further investigate its efficacy compared to […]
  • Development of the Diaphragmatic Paralysis Questionnaire: a simple tool for patient relevant outcome.
    Measurement tools of health-related quality of life (HRQL) that are specific for the underlying disorder are inevitably needed to assess HRQL changes following specific treatment strategies. The aim of the current study was to develop a questionnaire assessing HRQL in patients with unilateral diaphragmatic paresis.Firstly, topics of health impairments covering physical, psychological, social and functional […]
  • The significance of symptoms before and after surgery for anomalous aortic origin of coronary arteries in adolescents and adults.
    The aim of this study is to describe the significance of symptoms preoperatively and at medium-term follow-up in adolescent and adult patients who underwent surgery of anomalous aortic origin of a coronary artery (AAOCA).Consecutive patients who underwent surgery for AAOCA in our tertiary referral centre between 2001 and 2018 were included. Clinical characteristics and symptoms […]
  • A rare case of primary angiosarcoma of the anterior mediastinum.
    A 32-year-old male patient was initially diagnosed with fibrosing mediastinitis. The patient subsequently developed severe dyspnea and was further diagnosed with constrictive pericarditis due to the extent of fibrosing mediastinitis around the heart. Therefore, the patient underwent surgical resection of the fibrotic tissue in the anterior mediastinum including the pericardium and the pleura. Postoperative histological […]
  • Creating an appropriate access for endovascular repair by replacing a dissected femoral artery in aortic dissection.
    Transfemoral endovascular repair has been widely accepted as an effective treatment for type B aortic dissection. However, if the dissection extends to the femoral artery, the transfemoral approach increases the risk of access complications. We describe a case of acute complicated type B aortic dissection involving the dissected bilateral femoral arteries. Successful endovascular repair without […]
  • Cardiac haemangioma treated with surgical resection involving reconstruction of the right ventricle.
    A right ventricular cardiac tumour was incidentally detected in a 50-year-old woman during medical check-up. Transthoracic echocardiography, computed tomography and magnetic resonance imaging revealed that the right ventricular tumour was widely attached to the free wall of the right ventricle and extended to the right ventricular outflow tract. The tumour was excised surgically, and the […]
  • Comparison of cancer control between segmentectomy and wedge resection in patients with clinical stage IA non-small cell lung cancer.
    The study objective was to compare cancer control between segmentectomy and wedge resection in patients with clinical stage IA non-small cell lung cancer.Between 2010 and 2015, 457 patients with clinical stage IA (8th edition) non-small cell lung cancer undergoing wedge resection or segmentectomy were identified at 3 institutions. Propensity scores were calculated on the basis […]
  • Does metformin improve the efficacy of standard epidermal growth factor receptor-tyrosine kinase inhibitor treatment for patients with advanced non-small-cell lung cancer?
    A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was whether metformin improved the efficacy of standard epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatment for patients with epidermal growth factor receptor (EGFR)-mutated advanced non-small-cell lung cancer. A total of 99 papers were found using the reported […]