Immunoglobulin G of systemic sclerosis patients programs a pro-inflammatory and profibrotic phenotype in monocyte-like THP-1 cells. 24th November 2020 Functional IgG autoantibodies against diverse G protein-coupled receptors, i.e. antibodies with agonistic […]
Deep phenotyping of synovial molecular signatures by integrative systems analysis in rheumatoid arthritis. 24th November 2020 RA encompasses a complex, heterogeneous and dynamic group of diseases arising from […]
Efficacy, pharmacokinetics and safety of subcutaneous versus intravenous CT-P13 in rheumatoid arthritis: a randomized phase I/III trial. 24th November 2020 To assess non-inferiority of s.c. to i.v. CT-P13 in RA.Patients with active […]
Association of State Certificate of Need Regulation With Procedural Volume, Market Share, and Outcomes Among Medicare Beneficiaries. 24th November 2020 Certificate of need laws provide state-level regulation of health system expenditure. These […]
Risk factors for herpes zoster in patients with rheumatic diseases: a nationwide cohort study in Korea. 24th November 2020 To determine the risk factors for herpes zoster (HZ) in patients with […]
Visceral adiposity in patients with psoriatic arthritis and psoriasis alone and its relationship with metabolic and cardiovascular risk. 24th November 2020 Fat mass distribution, especially in the abdominal visceral region, has been rarely […]
Fetal safety of chloroquine and hydroxychloroquine use during pregnancy: a nationwide cohort study. 24th November 2020 The antimalaria 4-aminoquinoline drugs chloroquine and HCQ are used in the treatment […]
Secukinumab and ustekinumab treatment in psoriatic arthritis: results of a direct comparison. 24th November 2020 To evaluate the characteristics of patients (pts) with PsA treated by ustekinumab […]
Comparison between low cost USB nailfold capillaroscopy and videocapillaroscopy: a pilot study. 24th November 2020 Universal serial bus (USB) microscopy (capillaroscopy) could provide all rheumatologists with an […]
Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren’s syndrome. 22nd November 2020 To assess non-invasive imaging for detection and quantification of gland structure, inflammation […]
Macrophage activation syndrome in children with Kawasaki disease: an experience from a tertiary care hospital in northwest India. 22nd November 2020 To carry out a review of clinical characteristics, laboratory profiles, management and […]
Fracture risk in systemic lupus erythematosus patients over 28 years. 22nd November 2020 Chronic glucocorticoid use is complicated by osteoporosis and increases the risk of […]
Safety and therapeutic value of radiosynoviorthesis with yttrium-90: a Canadian single-centre experience. 22nd November 2020 Yttrium-90 (90Y) is approved in several countries as a radiosynoviorthesis agent in […]
Serum cytokine levels associated with myocardial injury in systemic lupus erythematosus. 22nd November 2020 To identify cytokines, markers of endothelial activation [soluble vascular cell adhesion molecule-1 […]
Causal association of adipokines with osteoarthritis: a Mendelian randomization study. 22nd November 2020 This two-sample Mendelian randomization study aimed to delve into the effects of […]
Proinflammatory and bone protective role of calcitonin gene-related peptide alpha in collagen antibody-induced arthritis. 22nd November 2020 Calcitonin gene-related peptide alpha (αCGRP) represents an immunomodulatory neuropeptide implicated in pain […]
Changing evidence over time: updated meta-analysis regarding anti-TNF efficacy in childhood chronic uveitis. 21st November 2020 To summarize evidence regarding efficacy of anti-TNFα in childhood chronic uveitis, refractory […]
Incidence of extra-articular manifestations in ankylosing spondylitis, psoriatic arthritis and undifferentiated spondyloarthritis: results from a national register-based cohort study. 20th November 2020 To estimate the incidence and strength of association of extra-articular manifestations [EAMs, […]
Tofacitinib counteracts IL-6 overexpression induced by deficient autophagy: implications in Sjögren’s syndrome. 20th November 2020 Altered homeostasis of salivary gland (SG) epithelial cells in Sjögren’s syndrome (SS) […]
Feasibility of online home spirometry in systemic sclerosis-associated interstitial lung disease: a pilot study. 19th November 2020 Frequent monitoring of forced vital capacity at home may be of added […]
Epidemiology of systemic sclerosis in the UK: an analysis of the Clinical Practice Research Datalink. 19th November 2020 We developed and tested a robust case ascertainment strategy within the Clinical […]
The efficacy and safety of citrate mixture vs sodium bicarbonate on urine alkalization in Chinese primary gout patients with benzbromarone: a prospective, randomized controlled study. 19th November 2020 To compare the efficacy and safety of citrate mixture and sodium bicarbonate […]
Differences in clinical characteristics of IgG4-related disease across age groups: a prospective study of 737 patients. 19th November 2020 The aim of this study was to compare the clinical characteristics of […]
The long-term prognosis of pneumomediastinum associated with dermatomyositis: a two-centre retrospective cohort study. 19th November 2020 Pneumomediastinum (PnM) is a rare but life-threatening complication of DM. The present […]
Geospatial clustering of childhood IgA vasculitis and IgA vasculitis-associated nephritis. 19th November 2020 Research on spatial variability of the incidence of IgA vasculitis (IgAV) in […]
Interleukin 6 receptor inhibition in primary Sjögren syndrome: a multicentre double-blind randomised placebo-controlled trial. 19th November 2020 No immunomodulatory drug has been approved for primary Sjögren’s syndrome, a systemic […]
Anti-centromere antibodies target centromere-kinetochore macrocomplex: a comprehensive autoantigen profiling. 19th November 2020 Anti-centromere antibodies (ACAs) are detected in patients with various autoimmune diseases such […]
Screening and Intervention to Prevent Falls and Fractures in Older People. 19th November 2020 Community screening and therapeutic prevention strategies may reduce the incidence of falls […]
Relationship between diffuse idiopathic skeletal hyperostosis and fragility vertebral fracture: a prospective study in older men. 17th November 2020 To analyse the risk of incident vertebral and non-vertebral fracture in men […]
Clinical significance of interleukin-18 for the diagnosis and prediction of disease course in systemic juvenile idiopathic arthritis. 17th November 2020 To investigate the clinical significance of serum IL-18 levels for the diagnosis […]
Peripheral blood mononuclear cells are hypomethylated in active rheumatoid arthritis and methylation correlates with disease activity. 17th November 2020 Epigenetic modifications are dynamic and influence cellular disease activity. The aim of […]
New insights into the role of imaging in polymyalgia rheumatica. 17th November 2020 PMR is an inflammatory rheumatic disease of elderly people characterized by pain […]
Sirolimus for patients with connective tissue disease-related refractory thrombocytopenia: a single-arm, open-label clinical trial. 17th November 2020 Connective tissue disease-related thrombocytopenia (CTD-TP) is a problematic disorder in clinical practice. […]
Efficacy of baricitinib in patients with moderate-to-severe rheumatoid arthritis with 3 years of treatment: results from a long-term study. 17th November 2020 To evaluate the long-term efficacy of once-daily baricitinib 4 mg in patients with […]
Efficacy and safety of fasinumab in patients with chronic low back pain: a phase II/III randomised clinical trial. 17th November 2020 To study the efficacy and safety of fasinumab in moderate-to-severe, chronic low […]
Relationship between Depression and Disease Activity in United States Veterans with Early Rheumatoid Arthritis Receiving Methotrexate. 16th November 2020 Depression is common in rheumatoid arthritis (RA) patients, exacerbates disease activity, and […]
Hydroxychloroquine suppresses interferon-inducible genes and B-cell activating factor in patients with incomplete and new onset systemic lupus erythematosus. 16th November 2020 Hydroxychloroquine (HCQ) is commonly used as first line treatment for systemic lupus […]
Relation between fatigue and ACR response in patients with psoriatic arthritis treated with TNFi therapy: a population-based cohort study. 16th November 2020 The objective of this population-based cohort study was to investigate the association […]
The performances of the ACR 1997, SLICC 2012, and EULAR/ACR 2019 classification criteria in pediatric systemic lupus erythematosus. 16th November 2020 Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. The ACR (American […]
Including pain, fatigue and physical function when assessing patients with early rheumatoid arthritis provides a comprehensive picture of disease burden. 16th November 2020 To explore the possibility of integrating patient-important outcomes like pain, fatigue and […]
Development and testing of reduced versions of the MMT-8 in juvenile dermatomyositis. 16th November 2020 To develop and test shortened versions of Manual Muscle Testing-8 (MMT-8) in […]
Risk of osteoarthritis in an incident cohort of people with psoriatic arthritis: a population-based cohort study. 16th November 2020 To determine the risk of a diagnosis of osteoarthritis (OA) in psoriatic […]
Lifestyle and clinical risk factors for incident rheumatoid arthritis-associated interstitial lung disease. 16th November 2020 To determine the association between novel lifestyle factors on risk of rheumatoid […]
Risk of cancer in middle-aged patients with gout: A nationwide population-based study in Korea. 16th November 2020 Gout is reportedly associated with a higher incidence of cancer. However, patients […]
Hospitalization Rates are Highest in the First 5 Years of Systemic Sclerosis: Results from a Population-based Cohort (1980-2016). 16th November 2020 Few studies have estimated the healthcare resource usage of patients with systemic […]
Descriptive Comparisons of the Impact of Apremilast and Methotrexate Monotherapy in Oligoarticular Psoriatic Arthritis: the Corrona Psoriatic Arthritis/Spondyloarthritis Registry Results. 16th November 2020 Therapeutic response was evaluated among new apremilast, methotrexate, or biologic disease-modifying anti-rheumatic […]
Concerns, healthcare use, and treatment interruptions in patients with common autoimmune rheumatic diseases during the COVID-19 pandemic. 16th November 2020 To assess concerns and healthcare-related behaviors of patients with autoimmune rheumatic diseases […]
Elaboration of a new synovial predictive score of septic origin for acute arthritis on the native joint (RESAS). 16th November 2020 To establish a new predictive score for the diagnosis of septic arthritis […]
Coeliac disease is a risk factor for the development of seronegative arthritis in patients with autoimmune thyroid disease. 16th November 2020 Hashimoto’s thyroiditis is known to cluster with other systemic autoimmune disorders. Rheumatic […]
Systemic overexpression of interleukin-22 induces the negative immune-regulator SOCS3 and potently reduces experimental arthritis in mice. 16th November 2020 High levels of IL-22 are present in serum and synovial fluid of […]
Increased Prevalence of Moderate-to-severe Mitral And Aortic Valve Dysfunction in Systemic Sclerosis: A Casecontrol Study. 16th November 2020 To investigate the prevalence, severity and associated clinical factors of mitral and […]
Individual responses to topical ibuprofen gel or capsaicin cream for painful knee osteoarthritis: a series of n-of-1 trials. 16th November 2020 To determine individual responses to ibuprofen gel or capsaicin cream for painful, […]
Priorities for High Quality Care in Rheumatoid Arthritis: Results of Patient, Health Professional, and Policymaker Perspectives. 16th November 2020 To elucidate the essential elements of high-quality rheumatoid arthritis (RA) care in […]
Baseline disease activity influences subsequent achievement of patient acceptable symptom state in Sjögren’s syndrome. 14th November 2020 To investigate longitudinal changes of the EULAR SS Patient-Reported Index (ESSPRI) and […]
Tuberculosis risk with biologics by screening-guided preventive strategy in rheumatoid arthritis under intermediate tuberculosis burden. 14th November 2020 We aimed to compare tuberculosis (TB) risk during biologics treatment between patients […]
Tofacitinib as a possible treatment for skin thickening in diffuse cutaneous systemic sclerosis. 14th November 2020 To analyse the effectiveness of tofacitinib for the treatment of refractory skin […]
The causal effect of interleukin-17 on the risk of psoriatic arthritis: a Mendelian randomization study. 14th November 2020 To determine causal associations between genetically predicted TNF-α, IL-12p70 and IL-17 levels […]
Changes in the illness perceptions of patients with rheumatoid arthritis over the first year of methotrexate therapy. 14th November 2020 To describe the illness perceptions of patients with RA over the first […]
A neutrophil signature is strongly associated with increased cardiovascular risk in gout. 14th November 2020 To investigate the association between neutrophil activation and cardiovascular risk in gout […]
Machine-learning, MRI bone shape and important clinical outcomes in osteoarthritis: data from the Osteoarthritis Initiative. 14th November 2020 Osteoarthritis (OA) structural status is imperfectly classified using radiographic assessment. Statistical shape […]
