Presenting Clinico-radiologic Features, Causes, and Clinical Course of Exogenous Lipoid Pneumonia in Adults. 1st March 2021 Exogenous lipoid pneumonia (ELP) develops when lipid-containing substances enter the airways through […]
Phenotypes and Subphenotypes of Patients with COVID-19: a Latent Class Modeling Analysis. 28th February 2021 Since COVID-19 was identified, its clinical and biological heterogeneity has been recognized. […]
The burden of mental illness among survivors of critical care – risk factors and impact on quality of life: a multicenter prospective cohort study. 28th February 2021 Survivors of critical care may develop mental health disorders in the months […]
Balancing the needs of the many and the few: where next for adult asthma guidelines? 27th February 2021 Asthma differs from many other chronic conditions in that most key management […]
Neutrophils in asthma: the good, the bad and the bacteria. 26th February 2021 Airway inflammation plays a key role in asthma pathogenesis but is heterogeneous […]
Repeatability and sensitivity to change of non-invasive end points in PAH: the RESPIRE study. 26th February 2021 End points that are repeatable and sensitive to change are important in […]
The pathophysiological role of novel pulmonary arterial hypertension gene SOX17. 26th February 2021 Pulmonary arterial hypertension (PAH) is a progressive disease predominantly targeting pre-capillary blood […]
Heterogeneity within and between physician-diagnosed asthma and/or COPD: NOVELTY cohort. 26th February 2021 Studies of asthma and chronic obstructive pulmonary disease (COPD) typically focus on […]
Altered pulmonary blood volume distribution as a biomarker for predicting outcomes in COVID-19 disease. 26th February 2021 Evidence suggests that vascular inflammation and thrombosis may be important drivers of […]
Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score. 26th February 2021 To develop and validate a prediction model of mortality in patients with […]
Bronchiectasis severity correlates with outcome in patients with primary antibody deficiency. 26th February 2021 Bronchiectasis is a well-recognised complication of primary antibody deficiency (PAD) syndromes. Previous […]
Classification and effectiveness of different oxygenation goals in mechanically ventilated critically ill patients: network meta-analysis of randomised controlled trials. 26th February 2021 The optimal oxygenation in mechanically ventilated critically ill patients remains unclear.Randomised controlled […]
Greenness may improve lung health in low-moderate but not high air pollution areas: Seven Northeastern Cities’ study. 26th February 2021 There is growing interest in the impact of greenness exposure on airway […]
Maternal asthma is associated with reduced lung function in male infants in a combined analysis of the BLT and BILD cohorts. 26th February 2021 Asthma in pregnancy is associated with respiratory diseases in the offspring.To investigate […]
Randomized Controlled Trial of Solriamfetol for Excessive Daytime Sleepiness in Obstructive Sleep Apnea: An Analysis of Subgroups Adherent or Nonadherent to Obstructive Sleep Apnea Treatment. 25th February 2021 Solriamfetol, a dopamine-norepinephrine reuptake inhibitor, is approved in the USA to improve […]
Arterial and venous thromboembolism in COVID-19: a study-level meta-analysis. 24th February 2021 The prevalence of venous thromboembolic event (VTE) and arterial thromboembolic event (ATE) […]
BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting. 24th February 2021 As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine […]
Characteristics and Prevalence of Domestic and Occupational Inhalational Exposures Across Interstitial Lung Diseases. 23rd February 2021 Inhalational exposures are increasingly recognized as contributing factors in interstitial lung disease […]
Comparative Effectiveness of Heart Rate Control Medications for the Treatment of Sepsis-Associated Atrial Fibrillation. 23rd February 2021 Atrial fibrillation (AF) with rapid ventricular response frequently complicates the management of […]
Immune checkpoint inhibitor-related pneumonitis in lung cancer: real-world incidence, risk factors, and management practices across six health care centers in North Carolina. 23rd February 2021 Immune checkpoint inhibitors (ICI) are standard treatments for advanced non-small cell lung […]
Outcomes of inhaled amikacin-containing multidrug regimens for Mycobacterium abscessus pulmonary disease. 23rd February 2021 Mycobacterium abscessus-pulmonary disease (MABS-PD) is challenging to treat due to its resistance […]
Progesterone in Addition to Standard of Care Versus Standard of Care Alone in the Treatment of Men Hospitalized with Moderate to Severe COVID-19: A Randomized, Controlled Pilot Trial. 23rd February 2021 Severity of illness in COVID-19 is consistently lower in women. Focus on […]
Outcomes and Resource Use Associated with Acute Respiratory Failure in Safety Net Hospitals Across the United States. 22nd February 2021 Despite the frequency and cost of hospitalizations for acute respiratory failure, there […]
Access to lung cancer screening in the Veterans Health Administration: Does geographic distribution match need in the population? 22nd February 2021 Studies show uneven access to Medicare-approved lung cancer screening (LCS) programs across […]
Clinical characteristics associated with lung function decline in individuals with adult-diagnosed cystic fibrosis: Contemporary analysis of the Canadian CF Registry. 22nd February 2021 Individuals diagnosed with cystic fibrosis (CF) as adults represent a rare but […]
Oxygen Therapy in Sleep Disordered Breathing. 21st February 2021 Sleep disordered breathing (SDB) is highly prevalent in adults and leads to […]
Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort. 21st February 2021 Whilst estimates of sub-optimal adherence to oral corticosteroids in asthma range from […]
Methodological Quality of Guidelines for Training or Competence Processes for Basic Point of Care Echocardiography in Critical Care – A Systematic Review of the Literature. 21st February 2021 The formulation of expert-opinion guidelines has several sources of bias that may […]
Identification and Remediation of Environmental Exposures in Patients with Interstitial Lung Disease: Evidence Review and Practical Considerations. 20th February 2021 A relationship between inhalational exposure to materials in the environment and development […]
Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study. 20th February 2021 Bronchiectasis is predominantly a neutrophilic inflammatory disease. There are no established therapies […]
ST2 is a biomarker of pediatric pulmonary arterial hypertension severity and clinical worsening. 20th February 2021 Pediatric pulmonary hypertension (PH) is a severe disease defined by sustained elevation […]
Dynamics of SARS-CoV-2 shedding in the respiratory depends on the severity of disease in COVID-19 patients. 19th February 2021 A fraction of COVID-19 patients progress to a severe disease manifestation with […]
Pulmonary Arterial Pruning and Longitudinal Change in Percent Emphysema and Lung Function: the COPDGene Study. 19th February 2021 Pulmonary endothelial damage has been shown to preceed the development of emphysema […]
Patient factors and temporal trends associated with COVID-19 in-hospital mortality in England: an observational study using administrative data. 18th February 2021 Analysis of the effect of COVID-19 on the complete hospital population in […]
Association between lung function of school age children and short-term exposure to air pollution and pollen: the PARIS cohort. 17th February 2021 Daily levels of ambient air pollution and pollen may affect lung function […]
Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: lung cancers and non-malignant end-stage respiratory diseases. 17th February 2021 Malignant and non-malignant respiratory diseases account for >4.6 million deaths annually worldwide. Despite […]
Effect of public health interventions on COVID-19 cases: an observational study. 17th February 2021 As the epidemic of COVID-19 is gradually controlled in China, a summary […]
Multiple breath washout (MBW) testing using sulfur hexafluoride: reference values and influence of anthropometric parameters. 17th February 2021 Multiple breath washout (MBW) using sulfur hexafluoride (SF6) has the potential to […]
Role of the IL-33/ST2 axis in cigarette smoke-induced airways remodelling in chronic obstructive pulmonary disease. 16th February 2021 Efficient therapy and potential prophylaxis are confounded by current ignorance of the […]
Systematic review and meta-analysis of anakinra, sarilumab, siltuximab and tocilizumab for COVID-19. 13th February 2021 There is accumulating evidence for an overly activated immune response in severe […]
Advanced Diagnostic and Therapeutic Bronchoscopy Technology and Reimbursement. 13th February 2021 Advanced interventional pulmonary procedures of the airways, pleural space, and mediastinum continue […]
How We Do It: Strategic Planning for the Chest Clinician. 13th February 2021 Having a strategic plan is important to reach organizational goals. Equally important […]
Long-term air pollution exposure under EU limits and adolescents’ lung function: Modifying effect of abnormal weight in GINIplus/LISA birth cohorts. 13th February 2021 Abnormal weights, e.g. Obesity, has shown strong modifying effect on the association […]
Long-term safety and efficacy of tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR (EXTEND): an open-label extension study. 13th February 2021 Tezacaftor-ivacaftor is an approved cystic fibrosis transmembrane conductance regulator (CFTR) modulator shown […]
Longitudinal effects of ivacaftor and medicine possession ratio in people with the Gly551Asp mutation: a 5-year study. 13th February 2021 Ivacaftor was the first therapy licensed to address the underlying defect in […]
Pulmonary hypertension in patients with chronic obstructive lung disease: results from COMPERA. 13th February 2021 Pulmonary hypertension in chronic obstructive pulmonary disease (PH-COPD) is a poorly investigated […]
Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model. 12th February 2021 The World Health Organization recommends standardised treatment durations for patients with tuberculosis. […]
Respiratory exacerbations are associated with muscle loss in current and former smokers. 12th February 2021 Muscle wasting is a recognised extra-pulmonary complication in chronic obstructive pulmonary disease […]
Severe respiratory syncytial virus disease in preterm infants: a case of innate immaturity. 12th February 2021 Respiratory syncytial virus (RSV) is the most common viral pathogen associated with […]
Simplified bedside assessment of pulmonary gas exchange in very preterm infants at 36 weeks’ postmenstrual age. 12th February 2021 We aimed to develop and validate a prediction table for a simplified […]
Combining pulmonary and cardiac computed tomography biomarkers for disease-specific risk modelling in lung cancer screening. 12th February 2021 Combined assessment of cardiovascular disease (CVD), chronic obstructive pulmonary disease (COPD), and […]
Can Simvastatin reduce COPD Exacerbations? A Randomised Double Blind Controlled Study. 12th February 2021 Several studies have shown that statins have beneficial effects in chronic obstructive […]
Diffusion Capacity Abnormalities for Carbon Monoxide in Patients with COVID-19 At Three-Month Follow-up. 12th February 2021 To evaluate pulmonary function and clinical symptoms in coronavirus disease 2019 (COVID-19) […]
Chest x-ray or CT for COVID-19 pneumonia? Comparative study in a simulated triage setting. 12th February 2021 for the management of patients referred to respiratory triage during the early […]
Expectation and dyspnea: The neurobiological basis of respiratory nocebo effects. 12th February 2021 Cues such as odours that do not per se evoke bronchoconstriction can […]
Clinical and Genetic Spectrum of Children with Primary Ciliary Dyskinesia in China. 12th February 2021 Primary ciliary dyskinesia (PCD) is a heterogeneous disease with a diverse clinical […]
Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study. 12th February 2021 To evaluate whether early initiation of prophylactic anticoagulation compared with no anticoagulation […]
Insights from Invasive Cardiopulmonary Exercise Testing of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. 12th February 2021 Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) affects tens of millions worldwide; the causes […]
Medium-term impact of COVID-19 on pulmonary function, functional capacity and quality of life. 12th February 2021 Coronavirus disease 2019 (COVID-19) has spread worldwide determining a dramatic impact on […]
Lung function & cardiovascular disease. A Two Sample Mendelian Randomisation Study. 12th February 2021 Observational studies suggest an association between reduced lung function and risk of […]
