β-blockade in sepsis: regulation of persisting sepsis-related tachycardia. 4th April 2020 Click here to read the full article @ The Lancet. Respiratory medicine
Personal strategies to minimise effects of air pollution on respiratory health: advice for providers, patients and the public. 4th April 2020 As global awareness of air pollution rises, so does the imperative to […]
Angiotensin Converting Enzyme 2 and Angiotensin (1-7) axis in Pulmonary Arterial Hypertension. 4th April 2020 In animal models of pulmonary arterial hypertension (PAH), angiotensin converting enzyme type […]
Mepolizumab in a population with severe eosinophilic asthma and corticosteroid dependence: results from a French early access programme. 4th April 2020 Mepolizumab was available in France as part of an early access programme […]
Long term noninvasive ventilation in the Geneva Lake area: indications, prevalence and modalities. 4th April 2020 Noninvasive ventilation (NIV) is standard of care for chronic hypercapnic respiratory failure […]
Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial. 4th April 2020 Tachycardia and atrial fibrillation frequently occur in patients being treated for sepsis […]
Echocardiography-derived stroke volume index is associated with adverse in-hospital outcomes in intermediate-risk acute pulmonary embolism: a retrospective cohort study. 4th April 2020 There remains uncertainty in the optimal prognostication and management of patients with […]
Combined treatment with hydrocortisone, vitamin C, and thiamine for sepsis and septic shock (HYVCTTSSS): A randomized controlled clinical trial. 4th April 2020 Whether hydrocortisone, vitamin C, and thiamine treatment can reduce the mortality of […]
Admission to hospital in the UK at a weekend does not influence the prognosis of adults with community-acquired pneumonia. 3rd April 2020 Outcomes for adults with community-acquired pneumonia (CAP) admitted to hospital at the […]
Mesenchymal folliculin is required for alveolar development: implications for cystic lung disease in Birt-Hogg-Dubé syndrome. 3rd April 2020 Pulmonary cysts and spontaneous pneumothorax are presented in most patients with Birt-Hogg-Dubé […]
EFFECTIVENESS AND SAFETY OF SUPERVISED HOME-BASED PHYSICAL TRAINING IN PATIENTS WITH COPD ON LONG-TERM HOME OXYGEN THERAPY: A RANDOMIZED TRIAL. 2nd April 2020 Patients with chronic obstructive pulmonary disease (COPD) in advanced disease stage who […]
Supervised pulmonary tele-rehabilitation versus pulmonary rehabilitation in severe COPD: a randomised multicentre trial. 2nd April 2020 Pulmonary rehabilitation (PR) is an effective, key standard treatment for people with […]
The Association of ICU Acuity with Adherence to ICU Evidence-Based Processes of Care. 2nd April 2020 Admission to high-acuity intensive care units (ICUs) has been associated with improved […]
Place of Death for Individuals with Chronic Lung Disease: Trends and Associated Factors from 2003 to 2017 in the United States. 2nd April 2020 Chronic lung disease is a common cause of mortality, yet little is […]
Interferon gamma replacement as salvage therapy in chronic pulmonary aspergillosis: effects on frequency of acute exacerbation and all-cause hospital admission. 2nd April 2020 Chronic pulmonary aspergillosis (CPA) is often poorly responsive to antifungal treatment; secondary […]
Use of Intravenous Immunoglobulin G in HIT patients is not associated with increased rates of thrombosis: A population-based study. 1st April 2020 Click here to read the full article @ Chest
Obstructive sleep apnea and neurocognitive impairment in children with congenital heart disease. 31st March 2020 Children with congenital heart disease (CHD) have an increased risk of neurocognitive […]
Can perturbations in microbial maturation cause asthma? 30th March 2020 Click here to read the full article @ The Lancet. Respiratory medicine
Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies. 30th March 2020 Childhood asthma incidence is decreasing in some parts of Europe and North […]
Abnormal Pulmonary Lymphatic Flow in Patients with Lymphatic Anomalies and Respiratory Compromise. 30th March 2020 Pulmonary involvement in lymphatic anomalies (LA) is associated with significant morbidity and […]
Duration of neonatal oxygen supplementation, erythropoiesis and blood pressure in young adults born preterm. 29th March 2020 Although erythropoiesis is impaired and anaemia frequent in neonates born preterm, haematopoiesis […]
Energy conservation technique improves dyspnoea when patients with severe COPD climb stairs: a randomised crossover study. 29th March 2020 In this randomised, crossover trial, 22 patients with severe chronic obstructive pulmonary […]
Isolated pulmonary embolism is associated with a high risk of arterial thrombotic disease – Results from the VTEval Study. 29th March 2020 Isolated PE is associated with a higher burden of atherosclerotic disease than […]
Cost-effectiveness of positive airway pressure modalities in obesity hypoventilation syndrome with severe obstructive sleep apnoea. 29th March 2020 Obesity hypoventilation syndrome (OHS) is treated with either non-invasive ventilation (NIV) or […]
β2 integrin LFA1 mediates airway damage following neutrophil trans-epithelial migration during RSV infection. 29th March 2020 RSV bronchiolitis is the most common cause of infant hospital admissions, but […]
Investigation of a unilateral pleural effusion: What CT scan coverage is optimal? 29th March 2020 The use of thoracic CT for patients presenting with a unilateral pleural […]
The natural history of progressive fibrosing interstitial lung diseases. 29th March 2020 We used data from the INBUILD and INPULSIS trials to investigate the […]
The safety of isoniazid tuberculosis preventive treatment in pregnant and postpartum women: systematic review and meta-analysis. 29th March 2020 The World Health Organization (WHO) recommends tuberculosis (TB) preventive treatment for high-risk […]
“Functional ageing in fibrotic interstitial lung disease: the impact of frailty on adverse health outcomes.” Sabina A. Guler, Joanne M. Kwan, Janice M. Leung, Nasreen Khalil, Pearce G. Wilcox and Christopher J. Ryerson. Eur Respir J 2020; 55: 1900647. 29th March 2020 Click here to read the full article @ The European respiratory journal
Acute exacerbations of chronic obstructive pulmonary disease: in search of diagnostic biomarkers and treatable traits. 29th March 2020 Acute exacerbations of chronic obstructive pulmonary disease (COPD) are associated with a […]
Correction: Percent low attenuation volume and fractal dimension of low attenuation clusters on computed tomography predict different long-term outcomes in COPD. 27th March 2020 Click here to read the full article @ Thorax
Childhood OSA is an independent determinant of blood pressure in adulthood: longitudinal follow-up study. 27th March 2020 Current literature supports cross-sectional association between childhood obstructive sleep apnoea (OSA) and […]
Respiratory syncytial virus treatment and the respiratory microbiome. 24th March 2020 Click here to read the full article @ The Lancet. Respiratory medicine
Identification of eight-protein biosignature for diagnosis of tuberculosis. 24th March 2020 Biomarker-based tests for diagnosing TB currently rely on detecting Mycobacterium tuberculosis (Mtb) […]
Infant respiratory syncytial virus prophylaxis and nasopharyngeal microbiota until 6 years of life: a subanalysis of the MAKI randomised controlled trial. 24th March 2020 Respiratory syncytial virus (RSV) infection during infancy is suggested to cause long-term […]
Immunotherapy in lung cancer: effective for patients with poor performance status? 23rd March 2020 Click here to read the full article @ The Lancet. Respiratory medicine
Pembrolizumab in patients with non-small-cell lung cancer of performance status 2 (PePS2): a single arm, phase 2 trial. 23rd March 2020 Therapeutic blockade of the axis of programmed cell death 1 (PD-1) and […]
Randomized trial on the effects of high-dose zopiclone on OSA severity, upper airway physiology and alertness. 22nd March 2020 Recent studies indicate that standard doses of hypnotics reduce or do not […]
Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism. 19th March 2020 Chronic thromboembolic pulmonary hypertension (CTEPH) is the most severe long-term complication of […]
Minimal clinically important differences for patient-reported outcome measures of fatigue in patients with COPD after pulmonary rehabilitation. 19th March 2020 Fatigue is a burdensome and prevailing symptom in patients with chronic obstructive […]
TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signaling. 19th March 2020 Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterised by myofibroblast proliferation […]
Derivation and Validation of a Diagnostic Prediction Tool for Interstitial Lung Disease. 19th March 2020 Interstitial lung disease (ILD) results in high morbidity and healthcare utilization. Diagnostic […]
Association between physical activity and risk of hospitalisation in bronchiectasis. 19th March 2020 Patients with bronchiectasis have a less active lifestyle than healthy peers, but […]
Diffusing Capacity is an Independent Predictor of Outcomes in Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease. 19th March 2020 Patients with chronic obstructive pulmonary disease (COPD) who develop pulmonary hypertension (PH) […]
FLCN-regulated miRNAs suppressed reparative response in cells and pulmonary lesions of Birt-Hogg-Dubé syndrome. 19th March 2020 Birt-Hogg-Dubé Syndrome (BHDS) characterised by skin fibrofolliculomas, kidney tumour and pulmonary cysts/pneumothorax […]
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma. 19th March 2020 Accumulating evidence highlights links between iron regulation and respiratory disease. Here, we […]
Mortality of cardiovascular events in COPD patients with preceding hospitalized acute exacerbation. 19th March 2020 Acute exacerbation (AE) of chronic obstructive pulmonary disease (COPD) may be accompanied […]
INCREASED CHITOTRIOSIDASE IS ASSOCIATED WITH ASPERGILLUS AND FREQUENT EXACERBATIONS IN SOUTH-EAST ASIANS WITH BRONCHIECTASIS. 19th March 2020 and Research Question: Chitinase activity is an important innate immune defence mechanism […]
COPD exacerbations: finally, a more than ACCEPTable risk score. 18th March 2020 Click here to read the full article @ The Lancet. Respiratory medicine
Blood transcriptional signatures for tuberculosis testing. 18th March 2020 Click here to read the full article @ The Lancet. Respiratory medicine
The Acute COPD Exacerbation Prediction Tool (ACCEPT): a modelling study. 18th March 2020 Accurate prediction of exacerbation risk enables personalised care for patients with chronic […]
Blood transcriptional biomarkers for active pulmonary tuberculosis in a high-burden setting: a prospective, observational, diagnostic accuracy study. 18th March 2020 Blood transcriptional signatures are candidates for non-sputum triage or confirmatory tests of […]
Pulmonary vascular and right ventricular burden during exercise in interstitial lung disease. 17th March 2020 Pulmonary hypertension (PH) adversely impact patient´s exercise capacity in interstitial lung disease […]
Maternal distress during pregnancy and recurrence in early childhood predicts atopic dermatitis and asthma in childhood. 17th March 2020 Using data from a provincial newborn screen and healthcare database for 12,587 […]
Change in V̇O2peak in response to aerobic exercise training and the relationship with exercise prescription in people with COPD: A systematic review and meta-analysis. 17th March 2020 We investigated the effect of aerobic training and exercise prescription on peak […]
Tracheal squamous cell papilloma with an aberrant artery in the stalk. 15th March 2020 Click here to read the full article @ Thorax
Limited use of biomarker-guided therapy in mild asthma. 15th March 2020 Click here to read the full article @ The Lancet. Respiratory medicine
Respiratory disease and Ramadan. 15th March 2020 Click here to read the full article @ The Lancet. Respiratory medicine
Predictive value of blood eosinophils and exhaled nitric oxide in adults with mild asthma: a prespecified subgroup analysis of an open-label, parallel-group, randomised controlled trial. 15th March 2020 Whether blood eosinophil counts and exhaled nitric oxide (FeNO) are associated with […]
Association Between Compliance with the Sepsis Quality Measure (SEP-1) and Hospital Readmission. 15th March 2020 Click here to read the full article @ Chest
