Osimertinib in Resected EGFR-Mutated Non-Small-Cell Lung Cancer. 21st September 2020 Osimertinib is standard-of-care therapy for previously untreated epidermal growth factor receptor (EGFR) […]
The spectrum of sleep disorders in Parkinson’s disease: a review. 21st September 2020 There is increasing interest in the effects of sleep and sleep disturbances […]
Leadership Essentials for the Chest Physician: Emotional Intelligence. 21st September 2020 Emotional intelligence (EI) has become widely appreciated as an important leadership attribute, […]
Analysis of Pneumothorax in Non-invasive Ventilator Users with Duchenne Muscular Dystrophy. 21st September 2020 With the advancement of cardio-respiratory interventions, the survival rate among patients with […]
A Perspective on the Educational “SWOTh” of the Coronavirus Pandemic. 21st September 2020 The coronavirus pandemic has disrupted clinical practice, healthcare organizations, and life. In […]
Leadership Essentials for the Chest Physician: Models, Attributes, and Styles. 21st September 2020 In the context that leadership matters and that leadership competencies differ from […]
“A National Survey of Burnout and Depression Among Fellows Training in Pulmonary and Critical Care Medicine: A Special Report by the APCCMPD. 21st September 2020 The prevalence of burnout and depressive symptoms is high among physician trainees.What […]
Effect of aspirin on deaths associated with sepsis in healthy older people (ANTISEPSIS): a randomised, double-blind, placebo-controlled primary prevention trial. 20th September 2020 Sepsis is a serious global health issue and a major cause of […]
Distinguishing smoking related lung disease phenotypes via imaging and molecular features. 18th September 2020 Chronic tobacco smoke exposure results in a broad range of lung pathologies […]
Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments. 18th September 2020 Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. […]
Tobacco and tobacco branding in films most popular in the UK from 2009 to 2017. 18th September 2020 Exposure to tobacco content in films is a cause of smoking uptake […]
Phagosome-regulated mTOR Signalling during Sarcoidosis Granuloma Biogenesis. 18th September 2020 Sarcoidosis and tuberculosis are granulomatous pulmonary diseases characterised by heightened immune reactivity […]
Exposure to household air pollution over 10 years is related to asthma and lung function decline. 18th September 2020 Are long-term Household Air Pollutions (HAPs) associated with asthma and lung function […]
Progressive fibrosing interstitial lung disease: a clinical cohort (the PROGRESS® study). 18th September 2020 In patients with chronic fibrosing interstitial lung disease (ILD), a progressive fibrosing […]
Asthma medication use in obese and healthy weight asthma: systematic review/meta-analysis. 18th September 2020 Obesity is a common co-morbidity in asthma and associated with poorer asthma […]
The Self-fulfilling Prophecy of Pulmonary Fibrosis: A Selective Inspection of Pathologic Signaling Loops. 18th September 2020 Pulmonary fibrosis is a devastating, progressive disease and carries a prognosis worse […]
Aspirin reduces cardiovascular events in patients with pneumonia: a prior event rate ratio analysis in a large primary care database. 18th September 2020 Ischaemic stroke and myocardial infarction (MI) are common after pneumonia and are […]
Effects of Random Measurement Error on Lung Cancer Screening Decisions:: A Retrospective-Cohort-Based Microsimulation Study. 17th September 2020 Self-reported tobacco pack-year history plays a large role in decisions about low-dose […]
Critically Ill Adults with COVID-19 in New Orleans and Care with an Evidence-based Protocol. 17th September 2020 Characteristics of critically ill adults with coronavirus disease 2019 (COVID-19) in an […]
Randomized Trial of Nocturnal Oxygen in Chronic Obstructive Pulmonary Disease. 16th September 2020 Long-term oxygen therapy improves survival in patients with chronic obstructive pulmonary disease […]
Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality: EPIC cohort study in 10 European countries. 16th September 2020 To determine if the Food Standards Agency nutrient profiling system (FSAm-NPS), which […]
A behaviour change intervention aimed at increasing physical activity improves clinical control in adults with asthma: a randomised controlled trial. 15th September 2020 Higher levels of physical activity have been associated with better asthma clinical […]
Exercise Pulmonary Resistances Predict Long-Term Survival in Systemic Sclerosis. 15th September 2020 Pulmonary hemodynamics during exercise may reveal early pulmonary vascular disease and be […]
Behavioral and regional brain responses to inhalation of capsaicin modified by painful conditioning in humans. 14th September 2020 Cough is a defense mechanism that protects the airways and lungs in […]
The COVID-19 Pandemic’s Impact on Critical Care Resources and Providers: A Global Survey. 14th September 2020 The COVID-19 pandemic has severely impacted Intensive Care Units (ICUs) and Critical […]
Maxim Integrated Smartphone Sensor with App Meets FDA/ISO Standards for Clinical Pulse Oximetry and can be Reliably Utilized by a Wide Range of Patients. 14th September 2020 Millions of smartphones contain a photoplethysmography (PPG) bio-sensor (Maxim Integrated, San Jose […]
A Cluster of Beryllium Sensitization Traced to the Presence of Beryllium in Concrete Dust. 14th September 2020 Chronic beryllium disease (CBD), a granulomatous disease with similarities to sarcoidosis, arises […]
Behavioral and regional brain responses to inhalation of capsaicin modified by painful conditioning in humans. 14th September 2020 Cough is a defense mechanism that protects the airways and lungs in […]
Maxim Integrated Smartphone Sensor with App Meets FDA/ISO Standards for Clinical Pulse Oximetry and can be Reliably Utilized by a Wide Range of Patients. 14th September 2020 Millions of smartphones contain a photoplethysmography (PPG) bio-sensor (Maxim Integrated, San Jose […]
A Cluster of Beryllium Sensitization Traced to the Presence of Beryllium in Concrete Dust. 14th September 2020 Chronic beryllium disease (CBD), a granulomatous disease with similarities to sarcoidosis, arises […]
SZ alpha-1 antitrypsin deficiency and pulmonary disease: more like MZ, not like ZZ. 12th September 2020 The ZZ genotype of alpha-1 antitrypsin deficiency (AATD) is associated with COPD […]
Effect of normobaric hypoxia on exercise performance in pulmonary hypertension – randomized trial. 12th September 2020 Many patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension (PH) wish […]
Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial. 12th September 2020 Despite inhaled corticosteroid plus long-acting β2-agonist (ICS/LABA) therapy, 30-50% of patients with […]
Composite type-2 biomarker strategy versus a symptom-risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial. 11th September 2020 Asthma treatment guidelines recommend increasing corticosteroid dose to control symptoms and reduce […]
Periostin: contributor to abnormal airway epithelial function in asthma? 10th September 2020 Periostin may serve as a biomarker for type-2-mediated eosinophilic airway inflammation in […]
Advances in understanding and reducing the burden of severe asthma in children. 10th September 2020 Severe asthma in children is rare, accounting for only a small proportion […]
The genetics of asthma and the promise of genomics-guided drug target discovery. 10th September 2020 Asthma is an inflammatory airway disease that is estimated to affect 339 […]
High-Flow Oxygen with Capping or Suctioning for Tracheostomy Decannulation. 9th September 2020 When patients with a tracheostomy tube reach a stage in their care […]
High-Flow Oxygen with Capping or Suctioning for Tracheostomy Decannulation. 9th September 2020 When patients with a tracheostomy tube reach a stage in their care […]
Long-term survival following initiation of home non-invasive ventilation: a European study. 8th September 2020 Although home non-invasive ventilation (NIV) is increasingly used to manage patients with […]
Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis. 8th September 2020 Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease characterized by progressive […]
Progressive fibrosing interstitial lung disease: clinical uncertainties, consensus recommendations, and research priorities. 6th September 2020 Within the spectrum of fibrosing interstitial lung diseases (ILDs) is a subset […]
A living WHO guideline on drugs for covid-19. 5th September 2020 What is the role of drug interventions in the treatment and prevention […]
Submaximal eccentric cycling in people with COPD: acute whole-body cardiopulmonary and muscle metabolic responses. 5th September 2020 Eccentric cycling (ECC) may be an attractive exercise modality in COPD due […]
Global physiology and pathophysiology of cough: Part 1. Cough phenomenology: CHEST Guideline and Expert Panel report. 5th September 2020 The purpose of this state-of-the-art review is to update the American College […]
Using Geospatial Analysis to Evaluate Access to Lung Cancer Screening in the United States. 5th September 2020 Screening current and former heavy smokers aged 55-80 years for lung cancer […]
Lung-targeting lentiviral vector for passive immunisation against influenza. 5th September 2020 When recombinant simian immunodeficiency virus (SIV) is pseudotyped with the F and […]
Allergen inhalation generates pro-inflammatory oxidised phosphatidylcholine associated with airway dysfunction. 5th September 2020 Oxidised phosphatidylcholines (OxPC) are produced under conditions of elevated oxidative stress and […]
Lesson of the month: novel method to quantify neutrophil uptake in early lung cancer using SPECT-CT. 5th September 2020 Neutrophils play an important role in the lung tumour microenvironment. We hypothesised […]
Effect of Early Balanced Crystalloids before ICU Admission on Sepsis Outcomes. 4th September 2020 Recent studies suggest using balanced crystalloids (lactated Ringer’s solution or Plasma-Lyte A) […]
Basic and Advanced Pleural Procedures Coding and Professional Fees Update for Pulmonologists. 4th September 2020 There is an evolution of pleural procedures involving broadened clinical indication and […]
“How to Review Post-lobectomy Posteroanterior Chest Radiographs”. 4th September 2020 Lung cancer is currently the most common malignancy in the world. A […]
A Tool to Assess Participation in People with COPD: Validation of the Late Life Disability Instrument. 4th September 2020 Participation in life roles is a critical patient-centred health outcome associated with […]
Real World Effectiveness of Benralizumab in Severe Eosinophilic Asthma. 4th September 2020 Benralizumab is an IL5-receptor monoclonal antibody licensed for the treatment of severe […]
Angiotensin II Infusion for Shock: A Multicenter Study of Post-Marketing Use. 4th September 2020 Vasodilatory shock refractory to catecholamine vasopressors and arginine vasopressin is highly morbid […]
Effectiveness of proton pump inhibitors in idiopathic pulmonary fibrosis: a population-based cohort study. 4th September 2020 Gastroesophageal reflux disease is a common co-morbidity in idiopathic pulmonary fibrosis (IPF) […]
Development and Validation of an Abridged Version of the REVEAL 2.0 Risk Score Calculator, REVEAL Lite 2, for use in Patients with Pulmonary Arterial Hypertension. 4th September 2020 Achievement of low-risk status is a treatment goal in pulmonary arterial hypertension […]
Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19: A Randomized Clinical Trial. 3rd September 2020 Coronavirus disease 2019 (COVID-19) is associated with severe lung damage. Corticosteroids are […]
Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial. 3rd September 2020 Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) is […]
Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis. 3rd September 2020 Effective therapies for patients with coronavirus disease 2019 (COVID-19) are needed, and […]
