The Latest Paediatric Dermatology Journal Articles
Keep up to date with the latest in paediatric dermatology. Check out the latest paediatric dermatology articles from leading medical journals in a single view, helping you discover relevant articles quickly and easily.
- An economic evaluation of the randomised controlled trial of topical corticosteroid and home-based narrowband UVB for active and limited vitiligo (The HI-Light Trial).Economic evidence for vitiligo treatments is absent.To determine the cost-effectiveness of (a) hand-held narrowband-UVB (NB-UVB) and (b) combination of topical corticosteroid (TCS) and NB-UVB compared to TCS for localised vitiligo.Cost-effectiveness analysis alongside a pragmatic, 3-arm, placebo-controlled RCT with 9 months’ treatment. 517 Adults and children (aged ≥5 years) with active vitiligo affecting <10% of skin […]
- Characteristics and Impacts of Itch in Children with Inflammatory Skin Disorders.Itch is a cardinal feature of pediatric disorders and can impair quality of life. However, few studies have addressed symptoms and impacts of itch in pediatric patients.We focused on understanding the child’s experience of itch and impact of itch specifically on affected children, including by comparison with the adult experience.Semi-structured interviews (9 parents/15 children with […]
- Characteristics and Impacts of Itch in Children with Inflammatory Skin Disorders.Itch is a cardinal feature of pediatric disorders and can impair quality of life. However, few studies have addressed symptoms and impacts of itch in pediatric patients.We focused on understanding the child’s experience of itch and impact of itch specifically on affected children, including by comparison with the adult experience.Semi-structured interviews (9 parents/15 children with […]
- Household Food Security and Infant Adiposity.Food insecurity has been associated with obesity, but previous studies are inconsistent and few included infants. We examined associations between household food security and infant adiposity and assessed the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and Supplemental Nutrition Assistance Program (SNAP) as effect modifiers. We hypothesized that infants from food-insecure households […]
- What’s new in atopic eczema? An analysis of systematic reviews published in 2018. Part 1: prevention and topical therapies.This review is part of a series of annual updates that summarize the evidence base for atopic eczema (AE). The aim is to provide a succinct guide for clinicians on the key findings from 14 systematic reviews on the prevention and topical treatment of AE published or indexed in 2018. Various supplements, including long-chain polyunsaturated […]
- Adolescents exposed to discrimination: are they more prone to excessive internet use?The Internet may serve as a suitable environment for discriminated adolescents as they may consider the online space as the place where they have possibility to build social ties they are missing in their offline life or manage their self-presentation. Therefore, our aim was to explore the association between different types of discrimination by peers […]
- Capillary malformation-arteriovenous malformation syndrome. A multicenter study.Capillary malformation-arteriovenous malformation (CM-AVM) syndrome is a rare syndrome that associates characteristic skin lesions with fast-flow vascular malformations (FFVM) in one-third of patients. Few case series have been described, and none in Spain.We conducted an observational study of patients with CM-AVM syndrome diagnosed in 15 Spanish hospitals over 3 years. The main clinical, radiological, genetic findings […]
- Hidradenitis Suppurativa in Pediatric Patients.Interest and research in Hidradenitis Suppurativa (HS) has grown over the decade, resulting in expanded knowledge on the associated comorbidities and treatment efficacy. Knowledge on pediatric onset HS is still limited, based upon case studies, small case series, and extrapolation from adult studies. With increasing prevalence of childhood obesity, lowering pubertal age and increasing awareness […]
- Prospective study of 5-day challenge with penicillins in children.To examine if a 5-day challenge with penicillin improves the diagnostic sensitivity compared with a single full dose in children with mild skin reactions.Subjects referred with suspected allergy to penicillin were consecutively included. Irrespectively of the morphology of the index reaction and the result of specific IgE, all subjects underwent a two-step titrated drug provocation […]
- Autosomal recessive hypotrichosis with loose anagen hairs associated with TKFC mutations.Loose anagen hair is a rare form of impaired hair anchorage in which anagen hairs that lack inner and outer root sheaths can be gently and painlessly plucked from the scalp. Usually occurring in children and often self-limiting, a genetic basis to the disorder has been suggested but not proven. A better understanding the aetiology […]
- International recommendations for an effective control of head louse infestations.Head louse infestations continue to be a concern of public health in most countries, including the most developed ones. The present recommendations are intended to inform and stress the role and impact of the different authorities, institutions, industry, and the public in the control of head lice in order to reduce the prevalence of this […]
- Diagnosis of Mycoplasma aetiology in Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis.We were pleased that the first national guidelines for paediatric Stevens-Johnson Syndrome (SJS) / Toxic Epidermal Necrolysis (TEN) were published in your journal last year1 . They highlighted the higher rate of infectious triggers in children compared to adults. This message is especially important for us, as author SW’s son had SJS/TEN triggered by Mycoplasma […]
- Water hardness and a possible genetic link with eczema in children.Previous studies have found a possible link between the risk of children developing atopic eczema, and hardness of the water used at home. The harder the water (containing more calcium), the more children seemed to develop eczema. Yet a study in children with eczema using water softeners to reduce water hardness had shown no difference […]
- Serum level and clinical significance of vitamin E in children with allergic rhinitis.Allergic rhinitis (AR) is one of the most prevalent allergic diseases in children. This study aimed to investigate the association between serum concentrations of vitamin E and AR to determine if the vitamin E level is correlated with the occurrence and severity of AR.A total of 113 children were enrolled in this cross-sectional study. Sixty-five […]
- Management of nail psoriasis.Nail involvement is estimated to affect 80-90% of patients with psoriasis at some point in their lives and is often associated with severe disease. Patients with nail involvement experience pain, functional impairment and social stigma, with significant restriction of daily activities and quality of life. Nail psoriasis is also considered a risk factor for the […]
- Shades of grey: what is paediatric psoriasiform dermatitis and what does it have in common with childhood psoriasis?While the majority of children with a chronic itchy rash suffer from atopic dermatitis (AD) and other forms of dermatitis, psoriasis is in the differential diagnosis. Certain patterns such as guttate and napkin psoriasis are accepted as classic paediatric psoriasis (PP), however there are many patients who do not fit these classic forms of OO […]
- Development of locally relevant clinical guidelines for procedure-related neonatal analgesic practice in Kenya: a systematic review and meta-analysis.Background Increasing numbers of neonates are undergoing painful procedures in low-income and middle-income countries, with adequate analgesia seldom used. In collaboration with a multi-disciplinary team in Kenya, we aimed to establish the first evidence-based guidelines for the management of routine procedure-related neonatal pain that consider low-resource hospital settings.We did a systematic review by searching MEDLINE, […]
- Development of locally relevant clinical guidelines for procedure-related neonatal analgesic practice in Kenya: a systematic review and meta-analysis.Background Increasing numbers of neonates are undergoing painful procedures in low-income and middle-income countries, with adequate analgesia seldom used. In collaboration with a multi-disciplinary team in Kenya, we aimed to establish the first evidence-based guidelines for the management of routine procedure-related neonatal pain that consider low-resource hospital settings.We did a systematic review by searching MEDLINE, […]
- Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study.The risk of vertical and perinatal transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, which causes COVID-19), the most appropriate management, and the neonate’s risk of developing COVID-19 during the perinatal period are unknown. Therefore, we aimed to elucidate best practices regarding infection control in mother-newborn dyads, and identify potential risk factors associated with […]
- Prostaglandin D2 metabolite is not a useful clinical indicator for assessing atopic dermatitis.Prostaglandin D2 (PGD2 ) plays an important role in atopic dermatitis (AD) and 11, 15-dioxo-9α-hydroxy-, 2, 3, 4, 5-tetranorprostan-1, 20-dioicacid (PGDM) is a major metabolite of PGD2 . We investigated the relationship between the urinary-PGDM levels and the severity of pediatric AD. Thirty-one AD and 21 non-AD subjects were recruited, and urinary-PGDM levels were measured. […]
- Clinical presentation, sonographic features and treatment options of segmental stiff skin syndrome: a case series.Segmental stiff skin syndrome (SSSS) is a rare genetic connective tissue disease, which is often misdiagnosed. High-frequency ultrasonography can represent a useful clinical adjunct in the differential diagnosis of this condition, in conjunction with the clinical and histopathological findings. Treatment options are limited and evidence is scarce. We present the clinical, sonographic and histological features […]
- Intensive care needs and long-term outcome of pediatric toxic epidermal necrolysis – A 10-year experience.Toxic epidermal necrolysis (TEN) is a life-threatening severe cutaneous adverse reaction. Data on pediatric TEN is limited.Case records of 44 children, 1 month-12 years with a diagnosis of TEN (>30% body surface area [%BSA] detachment) admitted to a tertiary pediatric intensive care unit (PICU) between 2009 and 2018 were analyzed retrospectively. The primary outcome was mortality, and […]
- Cutaneous Reactions in Children Treated with MEK Inhibitors, BRAF Inhibitors, or Combination Therapy: A Multi-Center Study.Treatment with BRAFI and MEKI causes cutaneous reactions in children limiting dosing or resulting in treatment cessation. The spectrum and severity of theses reactions is not defined.To determine the frequency and spectrum of cutaneous reactions in children on BRAFI and MEKI and their effects on continued therapy.A multi-center, retrospective study was conducted at 11 clinical […]
- Transcutaneous bilirubinometry during and after phototherapy in preterm infants: a prospective observational study.To examine the accuracy of transcutaneous bilirubinometry (TCB) measurements during and after phototherapy (PT) in preterm infants.Prospective observational cohort study.Level III neonatal centre.Preterm infants (from 23+0 to 36+6 weeks of gestation) born between June 2017 and May 2018 requiring PT.TCB was measured from an exposed area of the skin (the sternum; TCBU) and the covered […]
- The efficacy and safety of treatments for infantile hemangiomas: a Bayesian network meta-analysis.Whether infantile hemangiomas (IHs) need to be treated and which treatment should be preferred are still controversial. We aimed to compare and rank the treatments and identify the optimal treatment for IHs. We searched PubMed, EMBASE, the Cochrane Library, Web of Science, and other sources for randomized controlled trials up to August 2019. We included […]
- Scabies coexisting with other dermatoses: the importance of recognizing multiple pathologies in resource-poor settings.Background Skin Neglected Tropical Diseases (NTDs) are a group of ten diseases often co-endemic in African rural communities and characterized by primary skin involvement. If not diagnosed and treated promptly, they can lead to long-term disfigurement, disability, stigmatization, and socioeconomic loss. Scabies is a parasitic disease and it was added in 2017 to the World […]
- A Retrospective Multicenter Study of Fatal Pediatric Melanoma.Pediatric melanoma is rare and diagnostically challenging.Characterize clinical and histopathological features of fatal pediatric melanomas.Multi-center retrospective study of fatal melanoma cases in patients under 20 years diagnosed between 1994-2017.Of 38 cases of fatal pediatric melanoma identified, 57% presented in Caucasian patients and 19% in Hispanic patients. Average age at diagnosis was 12.7 years (range 0.0-19.9) […]
- Multisystem Inflammatory Syndrome in Children in New York State.A multisystem inflammatory syndrome in children (MIS-C) is associated with coronavirus disease 2019. The New York State Department of Health (NYSDOH) established active, statewide surveillance to describe hospitalized patients with the syndrome.Hospitals in New York State reported cases of Kawasaki’s disease, toxic shock syndrome, myocarditis, and potential MIS-C in hospitalized patients younger than 21 years […]
- The relationship of prenatal antibiotic exposure and infant antibiotic administration with childhood allergies: a systematic review.Early antibiotic exposure may be contributing to the onset of childhood allergies. The main objective of this study was to conduct a systematic review on the relationship between early life antibiotic exposure and childhood asthma, eczema and hay fever.Pubmed and Embase were searched for studies published between 01-01-2008 and 01-08-2018, examining the effects of (1) […]
- Review of Transition of Care Literature: Epidermolysis Bullosa, A Paradigm for Patients with Complex Dermatologic Conditions.Transition from pediatric to adult care is a critical component of healthcare for children with chronic needs. The characteristics of epidermolysis bullosa (EB) demand higher than average levels of provider support. There is consensus among health care professionals regarding the importance of transition, however, there is a scarcity of practical information regarding models for patients […]
- Malnutrition in children with ichthyosis: recommendations for monitoring from a multidisciplinary clinic experience.Short stature has been reported in congenital ichthyoses (CI) but little data exist on patients’ nutritional status.To describe the nutritional status at the first evaluation of children and young adults with CI.Prospective observational study of patients assessed at a multidisciplinary clinic. Clinical variables and ichthyosis severity were collected. Anthropometric assessment was made measuring weight and […]
- What’s new in atopic eczema? An analysis of systematic reviews published in 2018. Part 2: systemic therapies.This review forms part of an annual update series on atopic eczema (AE), where systematic reviews (SRs) are gathered and appraised to provide a summary of key recent research findings. The focus of this article is systemic therapies used in AE, while a review on prevention and topical therapies is provided in Part 1. In […]
- Pros and cons of pre-emptive screening programmes before peanut introduction in infancy.Peanut allergy is an important public health concern and causes substantial psychosocial comorbidity. Although fatal anaphylaxis is rare (occurring at 0·03-0·3 per million person-years in the general population), peanuts are one of the most frequent causes of food allergy mortality. The Learning Early About Peanut study transformed prevention of peanut allergy by showing that early […]
- Cross-Sectional Evaluation of the Pediatric Baseline Series in Detection of Contact Sensitization in Children.Click here to read the full article @ Journal of the American Academy of Dermatology
- Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: a systematic review.Alopecia areata (AA) is an immune-mediated disease resulting in non-scarring hair loss. Systematic reviews on the psychosocial and psychiatric comorbidities, health-related quality of life, and interventions targeting psychosocial well-being are limited.To conduct a systematic review of the psychosocial comorbidities, health-related quality of life, and treatment options targeting psychosocial well-being in adult and pediatric AA patients.A […]
- Views and experiences of managing eczema: systematic review and thematic synthesis of qualitative studies.The number of qualitative studies on eczema has increased rapidly in recent years. Systematically reviewing these can provide greater understandings of people’s perceptions of eczema and eczema treatments.We sought to systematically review and thematically synthesise qualitative studies exploring views and experiences of people with eczema and parents/carers of children with eczema.We searched MEDLINE, PsycINFO, CINAHL […]
- In-Hospital Formula Feeding and Breastfeeding Duration.In-hospital formula feeding (IHFF) of breastfed infants is associated with shorter duration of breastfeeding. Despite evidence-based guidelines on when IHFF is appropriate, many infants are given formula unnecessarily during the postpartum hospital stay. To account for selection bias inherent in observational data, in this study, we estimate liberal and conservative bounds for the association between […]
- A 8- year Bangladeshi girl with disseminated histoplasmosis, presented as chronic liver disease with portal hypertension: a rare case report.Histoplasmosis is a rare infectious condition with mainly pulmonary involvement. Disseminated histoplasmosis may occur in immunocompromised condition. It can present in different ways but jaundice and ascites is very uncommon.A 8- year old girl visited to department of pediatric gastroenterology & nutrition, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Child presented with fever, jaundice and […]
- Treatment persistence in paediatric and adolescent psoriasis patients followed into young adulthood: from topical to systemic treatment – a prospective, longitudinal, observational cohort study of 448 patients.Although solely topical treatment often suffices, psoriasis patients may require more intensive treatment (phototherapy and/or systemic treatments) to control their disease. However, in paediatric, adolescent and young adult patients, little is known about persistence of topical treatment and time until switch to systemic treatment.To determine median time from psoriasis onset until i) solely topical discontinuation […]
- A comparative case-control study of diagnostic criteria for atopic dermatitis and proposal of new diagnostic criteria from Tunisia.Atopic dermatitis (AD) is a heterogeneous disease. Thus, it is difficult to set up standard diagnostic criteria that cover the entire spectrum of AD patients. Our objectives were to study the epidemiologic characteristics of AD in Tunisia and to evaluate five diagnostic criteria (Hanifin and Rajka, Williams, Taieb and Boralevi, REACH and ISAAC questionnaire).This prospective […]
- Patient-Reported Outcomes for Measuring Sleep Disturbance in Pediatric Atopic Dermatitis: cross sectional study of PROMIS Pediatric Sleep Measures and Actigraphy.Most children with atopic dermatitis(AD) suffer from sleep disturbance, but reliable and valid assessment tools are lacking.To test PROMIS (Patient Reported Outcomes Measurement Information System) sleep measures in pediatric AD and to develop an algorithm to screen, assess and intervene to reduce sleep disturbance.A cross-sectional study was conducted with AD children ages 5-17 years and […]
- Classification of aplasia cutis congenita: a twenty-five-year review of cases presenting to a tertiary paediatric dermatology department.Aplasia cutis congenita (ACC) is a rare, congenital disorder characterized by localised or widespread absence of skin at birth with heterogeneous clinical presentation. The classification proposed by Frieden in 1986 is widely used.To establish whether, 34 years on, the Frieden classification still meets our needs.We conducted a retrospective chart review of all patients with a […]
- miRNA analysis of Childhood Atopic Dermatitis reveals a role for miR-451a.MicroRNAs (miRNAs), important regulators of gene expression, have been implicated in a variety of disorders. The expression pattern of miRNAs in pediatric atopic dermatitis (AD) has not been well studied.We sought to investigate miRNA expression profiles in different blood compartments of infants with AD.Small RNA and HTG-Edge sequencing were performed to identify differentially expressed miRNAs […]
- The challenging management of a series of 43 infants with Netherton syndrome: unexpected complications and novel mutations.Netherton syndrome (NS) is a rare disease caused by SPINK5 mutations, featuring variable skin and hair involvement and, in many cases, allergic manifestations with a risk of lethality particularly in infants. The clinical management is challenging.To analyse the clinical manifestations of a cohort of NS infants managed in a reference centre. To draw up recommendations […]
- Paediatric morphoea: a holistic review. Part 1: epidemiology, aetiopathogenesis and clinical classification.Morphoea, also known as localized scleroderma, is a debilitating fibrosing disorder of uncertain aetiology, affecting the skin and subcutaneous tissues. Paediatric-onset disease is not uncommon and is associated with frequent relapses. The disease has complex pathogenetic mechanisms and multiple clinical subtypes, and affects children of all ages. Recent research has focused on elucidating the disease […]
- Factors related to disagreement between self-reported versus objective measurement of allergen sensitization at a tertiary pediatric center in Beijing, China.The objectives of present study were to examine the level of disagreement between self-reported and objective measurement of sensitization to common inhalant allergens, and to explore the potential risk factors that might contribute to this discrepancy.A total of 215 children were enrolled from pediatric clinics at a tertiary pediatric center in Beijing, China. A survey […]
- Association between methylphenidate treatment and risk of seizure: a population-based, self-controlled case-series study.Individuals with attention-deficit hyperactivity disorder (ADHD) are at increased risk of seizures. Stimulant medications such as methylphenidate are the most commonly prescribed treatment for ADHD, but the association between their therapeutic use and the risk of seizures is unclear. We aimed to investigate the association between methylphenidate treatment and the risk of seizure.For this population-based […]
- Paediatric morphoea: a holistic review. Part 2: diagnosis, measures of disease activity, management and natural history.Paediatric morphoea is a debilitating fibrosing disorder of uncertain aetiology, affecting the skin and subcutaneous tissues. Defining optimum management strategies in paediatric morphoea remains an ongoing challenge, owing to the varied presentations and a relative paucity of paediatric-specific studies. We performed a literature search on PubMed, MEDLINE and Google Scholar, using keywords such as ‘pediatric […]
- New Onset Depression among Children, Adolescents, and Adults with Hidradenitis Suppurativa.Information on risk of depression among among children, adolescents and adults with hidradenitis suppurativa (HS) is limited.To compare risk of new-onset depression in HS patients with that of controls.Retrospective cohort analysis of 49,280 adult and 3,042 pediatric HS patients and matched controls identified using electronic health records data. Primary outcome was incident depression.Crude incidence rate […]
- Skin-to-Skin Care and COVID-19.Click here to read the full article @ Pediatrics
- Are decontamination measures effective in preventing recurrent staphylococcal skin infection in children?Click here to read the full article @ Archives of disease in childhood
- An epidemiological investigation of food allergy among children aged 3 to 6 in an urban area of Wenzhou, China.The prevalence of food allergy (FA) has increased worldwide. In China, the prevalence of FA in infants and school-aged children is well known, but the prevalence in preschool children is unknown.A total of 4151 preschool children aged 3 to 6 years in urban Wenzhou, China, were recruited for this cross-sectional study. Their parents completed a preliminary […]
- Forehead location and large segmental pattern of facial port-wine stains predict risk of Sturge-Weber Syndrome.Children with forehead port-wine stains (PWS) are at risk of Sturge-Weber Syndrome (SWS). However, most will not develop neurologic manifestations.To identify children at greatest risk of SWS.In this retrospective cohort study of children with forehead PWS, PWS were classified as “large segmental” (half or more of a contiguous area of hemi-forehead or median pattern) or […]
- Cutaneous mucinosis of infancy: a rare entity in pediatrics.Click here to read the full article @ International journal of dermatology
- Erythroderma in a newborn infant suggesting Omenn syndrome.Click here to read the full article @ The British journal of dermatology
- Room Costs for Common Pediatric Hospitalizations and Cost-Reducing Quality Initiatives.Improvement initiatives promote safe and efficient care for hospitalized children. However, these may be associated with limited cost savings. In this article, we sought to understand the potential financial benefit yielded by improvement initiatives by describing the inpatient allocation of costs for common pediatric diagnoses.This study is a retrospective cross-sectional analysis of pediatric patients aged […]
- Efficacy and safety of dupilumab in atopic dermatitis of the elderly: A retrospective study.Atopic dermatitis (AD) is a common inflammatory skin disease with high prevalence both in children (15-30%) and adults (2-10%); limited data are available for the elderly. Elderly patients are challenging showing frequent multiple comorbidities, associated polypharmacy, and common previously treatments failure. We performed a retrospective observational study on elderly (≥ 65 year-old) patients treated with […]
- Current Issues in the Treatment of Acne Vulgaris.Acne vulgaris is an extraordinarily common skin condition in adolescents. The mainstays of acne treatment have remained largely unchanged over recent years. In the context of increasing antibiotic resistance worldwide, there is a global movement away from antibiotic monotherapy toward their more restrictive use. Classically reserved for nodulocystic acne, isotretinoin has become the drug of […]
- A retrospective review of pregnancies on biologics for the treatment of dermatological conditions.Psoriasis often first presents in young adulthood, indeed the average age of diagnosis in women is 28, thus in the prime reproductive years. In addition, approximately 50% of pregnancies worldwide are unplanned. Although biologic therapies have revolutionised the treatment of moderate-to-severe psoriasis, there are no controlled studies of biologics in pregnant women. The increasing use […]
- A multivariate multilevel analysis of the risk factors associated with anthropometric indices in Iranian mid-adolescents.The present study was conducted to jointly assess some specific factors related to body fat measures using a multivariate multilevel analysis in a representative sample of Iranian mid-adolescents.This study was conducted among 2538 students (1286 boys) aged 14-20 years old, who were randomly selected among 16 public high schools by multi-stage random sampling procedure from all […]