The Latest Ocular Oncology Journal Articles

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Keep up to date with the latest in ocular oncology. Check out the latest ocular oncology articles from leading medical journals in a single view, helping you discover relevant articles quickly and easily

  • Unilateral retinoblastoma; natural history and an age-based protocol in 248 patients.
    We aimed to study the clinical state and prognosis of patients with unilateral retinoblastoma who were being treated at a paediatric comprehensive cancer centre in a limited-resource country, to assess the different phases of treatment and the success of different, more complex real-life models.In this retrospective study, we created a snapshot of our retinoblastoma database […]
  • Malignant acanthosis nigricans: a case report.
    To report a case of malignant acanthosis nigricans with two unusual aspects, including the patient’s young age and the development of filiform papillomas on the eyelid margins.A 30-year-old woman presented with dry eye symptoms. Examination revealed filiform papillomas on the eyelid margins, gums, lips, hands, and axillae and excessive pigmentation localized to the neck, axillae, […]
  • Postoperative severe visual impairment: surgical outcome of 165 patients with orbital tumours in the muscle cone.
    This study aimed to evaluate the risk factors of postoperative severe vision impairment (PSVI) for a primary orbital tumour in the muscle cone.A retrospective analysis of the patients who underwent orbitotomy for primary intraconal tumours at the Tianjin Medical University Eye Hospital from January 2010 to December 2015.A total of 165 cases of orbitotomy for […]
  • Association of Retinal Vascular Occlusion With Women Filling a Prescription for Female Hormone Therapy.
    Oral contraceptives have been associated with cardiovascular disease, ischemic stroke, venous thromboembolic disease, and breast cancer. Retinal vascular occlusions share the same risk factors as cardiovascular and cerebrovascular disease.To determine whether filling a prescription of female hormone therapy (FHT) is associated with an increased risk of retinal artery occlusion (RAO) or retinal vein occlusions (RVO).A […]
  • Optical coherence tomography angiography characteristics of choroidal melanoma.
    The purpose of this study is to evaluate tumour vasculature with optical coherence tomography angiography (OCTA) in malignant choroidal melanoma (CM).Patients with unilateral CM were included in this cross-sectional observational clinical study. Applying OCTA systems operating at 840-nm wavelengths, eyes with CM were imaged. The primary main outcome measures were OCTA images, qualitative evaluation of […]
  • Ophthalmic immune-related adverse events following anti-CTLA-4 or PD-1 therapy recorded in the American Academy of Ophthalmology IRIS® Registry.
    Detailed study of ophthalmic immune-related adverse events (OirAEs), including determination of incidence and recurrence rates, is of integral importance in the evolving field of cancer immunotherapy to inform management and treatment guidelines.Retrospective registry study SUBJECTS, PARTICIPANTS, AND/OR CONTROLS: Patients newly diagnosed with OirAEs between January 1, 2013 and December 31, 2017 in the American Academy […]
  • Optic nerve Hemangioblastoma with bilateral frontal lobe Oedema: a case report.
    Hemangioblastomas are rare benign tumours that are most commonly detected in the subtentorium or spinal cord. Optic nerve hemangioblastoma is very rare and is most commonly associated with Von Hippel-Lindau (VHL) syndrome.Here, we report a case of hemangioblastoma of the optic nerve with bilateral frontal lobe oedema without VHL syndrome, which has not yet been […]
  • SUBRETINAL DEPOSITS IN PREECLAMPSIA AND MALIGNANT HYPERTENSION: IMPLICATIONS FOR AGE RELATED MACULAR DEGENERATION (AMD).
    To describe the incidence of subretinal deposits that are similar in structure and stage on OCT imaging to subretinal drusenoid deposits (SDD) in AMD, in patients with hypertensive choroidopathy secondary to severe preeclampsia (PE) and malignant hypertension (MHT), and the implications of this ischemic choroidopathy for the pathophysiology of SDD in AMD.Retrospective cross-sectional study.33 PE […]
  • Prognostic value of TERT promoter mutations in conjunctival melanomas in addition to clinicopathological features.
    To evaluate the prognostic value of clinical, histopathological and molecular features and to relate different treatment modalities to clinical outcome in conjunctival melanomas (CM).Retrospective review of clinical, histopathological and BRAF V600E and telomerase reverse transcriptase (TERT) promoter mutation status and treatment modalities, correlated to recurrence and metastasis in 79 patients with CM, diagnosed between 1987 […]
  • Effect of Vitamin D and ω-3 Fatty Acid Supplementation on Risk of Age-Related Macular Degeneration: An Ancillary Study of the VITAL Randomized Clinical Trial.
    Observational studies suggest that higher intake or blood levels of vitamin D and marine ω-3 fatty acids may be associated with lower risks of age-related macular degeneration (AMD). However, evidence from randomized trials is limited.To evaluate whether daily supplementation with vitamin D3, marine ω-3 fatty acids, or both prevents the development or progression of AMD.This […]
  • Association of Vision Impairment With Preventive Care Use Among Older Adults in the United States.
    Preventive care is associated with decreased morbidity and mortality among older adults. Vision impairment may be a barrier to accessing care and health promotion information and therefore may contribute to decreased preventive care uptake.To examine the association between self-reported vision impairment and uptake of preventive care services (ie, breast and colon cancer screenings and influenza […]
  • Optical coherence tomography angiography characteristics of optic disc melanocytoma.
    Optic disc melanocytoma (ODMC) was a benign pigmented intraocular tumor with the rare potential malignant transformation. This study was designed to evaluate tumor vasculature with optical coherence tomography angiography (OCTA) in ODMC.Eyes of healthy individuals in a control group and of patients with ODMC were imaged by OCTA systems operating at 840 nm wavelengths and examined. […]
  • Primary orbital extraskeletal osteosarcoma and review of literature.
    Extraskeletal osteosarcoma is a malignant tumour composed of an osteoid and/or cartilaginous matrix; it arises in soft tissues without connection to the skeleton, and to our knowledge, this type of tumour is extremely rare.The present study reports a 57-year-old man with primary orbital extraskeletal osteosarcoma who presented with a history of painful swelling in the […]
  • Outcomes of intravitreal methotrexate to salvage eyes with relapsed primary intraocular lymphoma.
    To report the outcomes of intravitreal methotrexate (MTX) injections to rescue eyes with relapsed primary intraocular lymphoma (PIOL).Retrospective case series of patients with ocular relapse of PIOL who had initially received systemic chemotherapy (all five cases) and external beam radiotherapy (EBRT) to brain and orbits (two cases). Injections of MTX (400 µg/0.1 mL) were given one […]
  • Subclinical subretinal fluid detectable only by optical coherence tomography in choroidal naevi-the SON study.
    Subretinal fluid is a risk factor for growth and malignant transformation of choroidal naevi, however it is unclear if this applies to subclinical fluid that is only detectable by optical coherence tomography (OCT). The objective of this study was to determine the prevalence and associations of subclinical but OCT-detectable subretinal fluid over choroidal naevi.Cross-sectional study […]
  • Diagnostic and treatment challenges of a case of primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid.
    Primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid is an extremely rare but aggressive neoplasm diagnosed primarily in elderly men. Until now there are 32 published cases of signet-ring cell carcinoma or histiocytoid carcinoma of the eyelid. We report the clinical, radiographic and histological features of the 33rd reported case of PCSRCC in the eyelid […]
  • Dual Sensory Impairment and Perceived Everyday Discrimination in the United States.
    Perceived everyday discrimination is a psychosocial stressor linked to adverse health outcomes, including mortality.To assess the association of vision impairment (VI), hearing impairment (HI), and dual sensory impairments (DSI) with everyday discrimination.Cross-sectional analysis of the Health and Retirement Study 2006 and 2008 surveys, a US population-based survey that included noninstitutionalized adults 51 years and older. […]
  • Limbal stem cell deficiency secondary to systemic paclitaxel (Taxol) for breast cancer: a case report.
    Paclitaxel (PTX) is an antineoplastic drug widely used in treatments for ovarian, breast, and small-cell lung cancer. Although ocular effects associated with PTX have been previously described, very few studies have specifically reported systemic PTX as a contributing factor for limbal stem cell deficiency (LSCD), which is characterized by the loss of stem cell and […]
  • Utility of PAX8 immunohistochemistry in adult intraocular tumor diagnosis.
    To evaluate the distribution of the PAX8 transcription factor protein in ocular tissues and to investigate if immunohistochemical stains for this biomarker are useful in the diagnosis of intraocular tumors DESIGN: Observational case series.Excisions and cytology specimens of 6 ciliary body epithelial neoplasms, 2 iris epithelial neoplasms, 3 retinal pigment epithelial neoplasms, 3 intraocular medulloepitheliomas, […]
  • Increased risk of cancer in patients with retinal vein occlusion: a 12-year nationwide cohort study.
    To investigate the association between incident retinal vein occlusion (RVO) and the subsequent development of cancer.In this nationwide population-based retrospective study using 2002-2013 National Health Insurance Service database which covers the entire South Korean population, 186 701 incident RVO patients and their 1:1 propensity-score matched controls were included. We defined the fixed cohort from January 1st, […]
  • Clinical spectrum of uveal metastasis in Korean patients based on primary tumor origin.
    To describe the clinical features and prognosis of patients with uveal metastasis in Korea.Retrospective observational case series.Patients diagnosed at two tertiary high-volume centers between November 2005 and November 2019.Evaluation of multimodal imaging and electronic records.The clinical features and outcomes were assessed based on the primary cancer site.A total of 134 uveal metastases (128 choroidal, 3 […]
  • Travel burden and clinical presentation of retinoblastoma: analysis of 1024 patients from 43 African countries and 518 patients from 40 European countries.
    The travel distance from home to a treatment centre, which may impact the stage at diagnosis, has not been investigated for retinoblastoma, the most common childhood eye cancer. We aimed to investigate the travel burden and its impact on clinical presentation in a large sample of patients with retinoblastoma from Africa and Europe.A cross-sectional analysis […]
  • Adjuvant use of laser in eyes with macular retinoblastoma treated with primary intravenous chemotherapy.
    Adjuvant use of laser with systemic chemotherapy for treatment of retinoblastoma may reduce recurrence rates while also causing local side effects. Information is lacking on the effect of laser on visual outcomes.A retrospective review of two retinoblastoma centres in the United Kingdom was conducted. Patients were included if there was a macular tumour in at […]
  • Anterior Segment OCTA of Melanocytic Lesions of the Conjunctiva and Iris.
    To study the feasibility and diagnostic value of vascular imaging using OCT-Angiography (OCTA) of melanocytic lesions of the conjunctiva and iris. Design; Cross-sectional study.Twenty-five patients with an untreated conjunctival lesion (5 melanoma, 13 nevus, 7 primary acquired melanosis (PAM) and 52 patients with an untreated iris lesion (10 melanoma, 42 nevus) were included. Patients were […]
  • Orbital disease in neuro-ophthalmology.
    Orbital disease represents a diverse spectrum of pathology and can result in a variety of neuro-ophthalmic manifestations. The aim of this review is to provide updates on recent advances in our understanding of orbital disease secondary to thyroid eye disease, myositis, IgG4-related disease, sarcoidosis, granulomatosis with polyangiitis and various tumours.With regards to thyroid eye disease, […]
  • Conjunctival melanoma treatment outcomes in 288 patients: a multicentre international data-sharing study.
    To relate conjunctival melanoma characteristics to local control.Retrospective, registry-based interventional study with data gathered from 10 ophthalmic oncology centres from 9 countries on 4 continents. Conjunctival melanoma patients diagnosed between January 2001 and December 2013 were enrolled in the study. Primary treatments included local excision, excision with cryotherapy and exenteration. Adjuvant treatments included topical chemotherapy, […]
  • Long term outcomes of small pigmented choroidal melanoma treated with primary photodynamic therapy.
    To report the long-term outcomes of patients with small, pigmented posteriorly located choroidal melanoma undergoing primary treatment using photodynamic therapy (PDT) with verteporfin at the London Ocular Oncology Service.Retrospective interventional consecutive case series SUBJECTS: All patients undergoing primary treatment using PDT with verteporfin from April 2014 and December 2015 and followed until December 2019.This is […]
  • Small choroidal melanoma: outcomes following apical height dose brachytherapy.
    To assess the outcomes of small choroidal melanoma following iodine-125 episcleral brachytherapy (apical height dose of 85 Gy).Patients with small choroidal melanoma that underwent iodine-125 episcleral brachytherapy between January 2004 and December 2017 were reviewed. Inclusion criterion for this study was the COMS small tumour size (tumour apical height of 1.0-2.5 mm and largest basal diameter […]
  • Nationwide trends in the incidence of orbital lymphoma from 1999 to 2016 in South Korea.
    Lymphomas are the most frequent neoplasm of the orbit. However, the epidemiology of orbital lymphomas is not well reported. This study aimed to provide a population-based report on the epidemiology of orbital lymphomas and measure the trends in the incidence of orbital lymphoma cancer in South Korea.Nationwide cancer incidence data from 1999 to 2016 were […]
  • Gene fusions in ocular adnexal tumors.
    To highlight the increasing importance of gene fusions in the diagnosis, prognosis, and therapy of ocular adnexal tumors.A perspective.A focused review of gene fusions, their pathogenic mechanism, and gene fusion detection methods in lacrimal gland and primary orbital and ocular adnexal soft tissue tumors; reappraisal of diagnostic, prognostic, and therapeutic approach to ocular adnexal tumors […]
  • Focal choroidal excavation: review of literature.
    Focal choroidal excavation (FCE) is defined as an area of concavity in choroid detected on optical coherence tomography. These are mostly present in macular region without evidence of accompanying scleral ectasia or posterior staphyloma. Though initially considered to be congenital, increasing number of cases have been identified in association with other choroidal pathologies such as […]
  • Retinal vasculometry associations with glaucoma; findings from the European Prospective Investigation of Cancer-Norfolk Eye study.
    To examine retinal vasculometry associations with different glaucomas in older British people.Cross-sectional study METHODS: 8,623 European Prospective Investigation into Cancer-Norfolk Eye study participants were examined, who underwent retinal imaging, ocular biometry assessment, and clinical ascertainment of ocular hypertensive or glaucoma status (including glaucoma suspect [GS], high tension open-angle glaucoma [HTG], and normal tension glaucoma [NTG]). […]
  • Power to see: Drivers of aerobic glycolysis in the mammalian retina – A review.
    The mammalian retina converts most glucose to lactate rather than catabolising it completely to carbon dioxide via oxidative phosphorylation, despite the availability of oxygen. This unusual metabolism is known as aerobic glycolysis or the Warburg effect. Molecules and pathways that drive aerobic glycolysis have been identified and thoroughly studied in the context of cancer but […]
  • Bacillary Layer Detachment in Bilateral Diffuse Uveal Melanocytic Proliferation Masquerading as Neovascular AMD.
    Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare and unusual paraneoplastic ocular syndrome with generally poor prognosis. The authors present a case of BDUMP in a patient with bladder cancer, examined with current multimodal imaging. In the clinical setting with drusen and exudative macular detachments, the fundus simulated neovascular age-related macular degeneration, warranting standard-of-care […]
  • Reduction in Mammography Screening for Breast Cancer Among Visually Impaired Women.
    Timely receipt of mammograms to screen for breast cancer in accordance with the United States Preventive Services Task Force (USPSTF) recommendations can substantially reduce morbidity and mortality. The purpose of this study is to assess whether odds of receiving screening mammograms are similar for women with and without visual impairment.Retrospective longitudinal cohort study.1044 females, 65-72 […]
  • How Telemedicine and Centralized Care Changed the Natural History of Retinoblastoma in a Developing Country: Analysis of 478 Patients.
    To evaluate the efficacy of integrating telemedicine-based twinning partnership and centralized care for Retinoblastoma (RB) on survival and eye salvage.A cohort of 478 RB patients from 2003 to 2019 treated at tertiary referral cancer center (King Hussein Cancer Centre, KHCC).478 RB patients who were treated at KHCC after implementing a telemedicine-based program with St. Jude […]
  • Unique geospatial accumulations of uveal melanoma.
    Uveal melanoma (UM) is the most common primary malignant eye tumor in adults, though rare with 2500 cases diagnosed annually in the US. Despite a growing understanding of the molecular characteristics, there remains uncertainty regarding epidemiologic trends and environmental risk factors. We have identified three geographic accumulations of UM: 1) Huntersville, NC, 2) Auburn, AL, […]
  • Invasive conjunctival melanoma mimicking ocular surface squamous neoplasia: a case series.
    Conjunctival melanoma is the second most common conjunctival malignant tumour after squamous cell carcinoma, usually arising from primary acquired melanosis and less commonly from a conjunctival naevus or de novo. We report four cases of conjunctival melanoma masquerading as ocular surface squamous neoplasia.Four patients (2 females and 2 males; mean age 60.7 years; range 41-72 years) were […]
  • Iodine-125 interstitial brachytherapy for malignant lacrimal sac tumours: an innovative technique.
    Primary malignant tumours of the lacrimal sac are rare, surgery and radiotherapy may induce substantial side effects for patients. Here, this article reports an innovative technique of interstitial brachytherapy developed for the treatment of malignant lacrimal sac tumours.Four patients (male 3, female 1), with an average age of 52.7 years (range 41-72 years), were individually […]
  • Primary photodynamic therapy for small amelanotic choroidal melanomas: consecutive case series of 69 patients with at least 24-month follow-up.
    To investigate the success and recurrence rates and visual outcomes in a large case series of amelanotic posterior choroidal melanomas treated by means of primary photodynamic therapy (PDT) with verteporfin.Retrospective case series from a single specialist ocular oncology centre. All patients had a clinical diagnosis of choroidal melanoma and were selected for PDT based on […]
  • Is intravitreal topotecan toxic to retinal function?
    Intravitreal injections of topotecan are used in the management of retinoblastoma with vitreous seeds. This study evaluated whether intravitreal topotecan was associated with retinal toxicity.Retrospective cohort study of patients with retinoblastoma who were treated with intravitreal topotecan at Memorial Sloan Kettering Cancer Center between December 2014 and May 2019. Electroretinogram (ERG) responses under anaesthesia were […]
  • Periorbital, conjunctival and primary intraorbital carcinomas: Survival and risk factors after orbital exenteration.
    This study aimed to analyse the disease-free survival (DFS), overall survival (OS) and risk factors after orbital exenteration in patients with periorbital, conjunctival and primary intraorbital carcinomas.Patients undergoing orbital exenteration due to a primary carcinoma between March 2000 and March 2018 were included in this retrospective study. Risk factors in all the patients were evaluated […]
  • OCT changes in peri-tumour normal retina following ruthenium-106 and proton beam radiotherapy for uveal melanoma.
    Uveal melanoma is most commonly treated with radiotherapy, destroying the tumour cells with adequate safety margins and limiting collateral damage to surrounding structures to preserve maximal vision. We used optical coherence tomography (OCT) to study the effects of radiotherapy on the retina.Patients with posteriorly located choroidal melanoma treated with proton beam radiotherapy (PBR) and ruthenium-106 […]
  • Vogt-Koyanagi-Harada disease-like uveitis following nivolumab administration treated with steroid pulse therapy: a case report.
    Immune checkpoint inhibitors can cause various adverse effects. Recently it has been shown that Vogt-Koyanagi-Harada (VKH) disease-like uveitis can occur in patients treated with nivolumab.A 69-year-old man developed bilateral panuveitis after nivolumab treatment for recurrent hypopharyngeal cancer. Slit lamp examination revealed bilateral granulomatous keratic precipitates, anterior chamber cells and partial synechiae. Fundus examination revealed bilateral […]
  • Profiling ocular surface responses to preserved and non-preserved topical glaucoma medications: a two-year randomised evaluation study.
    Use of topical glaucoma medications has been reported to cause ocular surface (OS) discomfort and inflammation. This study explores the profile of inflammatory cytokines and OS symptoms induced in response to preserved and non-preserved drops.Prospective, randomized evaluation on thirty-six treatment-naïve patients over 24 months of three differently preserved glaucoma drop preparations: Preservative-free (PF), Polyquad (PQ), […]
  • Assessment of inner retina layers thickness values in eyes with pituitary tumours before visual field defects occur.
    The purpose of this study was to evaluate macula, retinal nerve layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL) and macular nerve fibre layer (mNFL) thickness in patients with pituitary tumours who has normal visual field (VF).Thirty-five eyes of 35 patients with pituitary tumours with normal VF and 41 eyes of 41-healthy subjects […]
  • Artificial intelligence for anterior segment diseases: Emerging applications in ophthalmology.
    With the advancement of computational power, refinement of learning algorithms and architectures, and availability of big data, artificial intelligence (AI) technology, particularly with machine learning and deep learning, is paving the way for ‘intelligent’ healthcare systems. AI-related research in ophthalmology previously focused on the screening and diagnosis of posterior segment diseases, particularly diabetic retinopathy, age-related […]
  • A Multicenter, International Collaborative Study for AJCC-Staging of Retinoblastoma: Treatment Success and Globe Salvage.
    To evaluate the ability of the 8th edition of the American Joint Committee on Cancer (AJCC) Staging to predict local tumor control and globe salvage for children with retinoblastoma (RB).International, multicenter, registry-based retrospective case series PARTICIPANTS: 2854 eyes of 2097 patients from 18 ophthalmic oncology centers from 13 countries over 6 continents.International, multicenter, registry-based data […]
  • Nuclear expression of BAP-1 in transvitreal incisional biopsies and subsequent enucleation of eyes with posterior choroidal melanoma.
    As a majority of patients with choroidal melanoma do not undergo enucleation, tumour tissue for prognostic testing has to be obtained with alternate methods. Transvitreal incisional biopsies enable histological examination as well as immunohistochemical staining of BRCA1-associated protein-1 (BAP-1).Fifty-nine patients diagnosed with choroidal melanoma in transvitreal biopsies between years 2003 and 2019 were included. Twenty-one […]
  • Scleral concave pool trabeculectomy combined phacoemulsification in primary open-angle glaucoma with cataract.
    To investigate the safety and efficacy of scleral concave pool trabeculectomy (SCPT) combined phacoemulsification for eyes with coexisting cataract and primary open-angle glaucoma (POAG).This was a retrospective, controlled, interventional pilot case series. Thirty patients (30 eyes) were diagnosed with coexisting cataract and POAG between May 2015 and April 2018. Fourteen eyes underwent SCPT combined phacoemulsification […]
  • Bilateral multiple serous retinal detachments after treatment with nivolumab: a case report.
    Immune checkpoint inhibitors have recently been widely used for advanced cancers and are known to cause ocular complications. We herein report a case developing bilateral serous retinal detachments, without ocular inflammation, after starting nivolumab treatment.A 73-year-old man was referred to our hospital, having become aware of metamorphopsia 2 months after starting nivolumab (anti-programmed cell death […]
  • A Multicenter, International Collaborative Study for AJCC-Staging of Retinoblastoma: Metastasis-Associated Mortality.
    To evaluate the ability of the 8th edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual to estimate metastatic and mortality rates for children with retinoblastoma(RB).International, multicenter, registry-based retrospective case series PARTICIPANTS: 2190 patients from 18 ophthalmic oncology centers from 13 countries over 6 continents.Patient-specific data fields for RB were designed by […]
  • Endogenous Endophthalmitis successfully treated with Intravitreal Povidone-iodine injection: a case report.
    The usefulness of povidone-iodine as an alternative to antimicrobial agents, for endophthalmitis, has recently been documented. We report a case of endogenous endophthalmitis successfully treated with intravitreal injection of povidone-iodine.An 88-year-old woman underwent small bowel bypass surgery for postoperative ileus following rectal cancer resection. She developed a fever during total parenteral nutrition and was diagnosed […]
  • Anterior lamellar deficit ectropion management.
    To report the outcomes of using a modified Bick’s procedure (MBP) combined with a monopedicle myocutaneous flap (MMCF) or full-thickness skin grafting (FTSG) to correct lower eyelid cicatricial ectropion.A retrospective case-note review of patients undergoing cicatricial ectropion repair between 2012 and 2016 was undertaken. Patient demographics, clinical features, the type of surgery, and outcomes were […]
  • Effect of plaque brachytherapy dose and dose rate on risk for disease-related mortality in 1238 patients with choroidal melanoma.
    Episcleral brachytherapy is the most common treatment for medium-sized choroidal melanomas. Although controversial, inadequate brachytherapy dose and dose rates have at least a hypothetical implication on patient survival.All patients who received ruthenium-106 or iodine-125 brachytherapy for choroidal melanoma at St. Erik Eye Hospital 1996 to 2016 were included (n=1238). Cox regression hazard ratios for melanoma-related […]
  • Recommendations for long-term follow-up of adults with heritable retinoblastoma.
    Generate recommendations for long-term follow-up for adult survivors of heritable retinoblastoma.We convened a meeting of providers from retinoblastoma centers around the world to review the state of the science and to evaluate the published evidence.Retinoblastoma is a rare childhood cancer of the retina. Approximately forty percent of retinoblastoma cases are heritable, due to a germline […]
  • CT and MRI findings in relapsing primary malignant melanoma of the lacrimal sac: a case report and brief literature review.
    Primary lacrimal sac melanoma is an extremely rare condition with fewer than 50 cases reported so far. Clinically, its symptoms resemble those of dacryocystitis, leading to frequent misdiagnosis. During diagnosis, imaging examination is often performed to differentiate tumors from inflammation. In this report, we present a case of primary lacrimal sac melanoma and summarize the […]
  • Ultra-wide-field imaging assessment of small choroidal pigmented lesions using red and green colour channels.
    Diagnosis of small choroidal melanoma is mainly based on tumour thickness, subretinal fluid, or lipofuscin pigment. Ultra-wide-field imaging (UWF) allows depiction of choroidal lesions through a red (RC) and a green channel (GC). Aim of the study was to determine the utility of this tool in the detection of small choroidal melanoma.Retrospective cross-sectional study of […]
  • Retinoblastoma presentation, treatment and outcome in a large referral centre in Tehran: a 10-year retrospective analysis.
    Early diagnosis, care and treatment of retinoblastoma is a challengeable issue for Iranian health system. This study was designed and conducted in a referral multidisciplinary centre in the capital city of Iran to evaluate management, care, prognosis and survival rates of paediatric patients with retinoblastoma.In this retrospective study, a total number of 309 patients younger […]
  • Management of conjunctival melanoma with local excision and adjuvant brachytherapy.
    To evaluate the management of conjunctival melanoma with local excision and adjuvant brachytherapy.Data of all patients who received local excision and adjuvant brachytherapy for conjunctival melanoma between 1999 and 2016 in a Dutch national referral centre were reviewed. A protocol with Sr-90 was used until 2012, a protocol with Ru-106 was used hereafter. Local recurrence, […]