- SPG7 mutations in amyotrophic lateral sclerosis: a genetic link to hereditary spastic paraplegia.
Amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP) are motor neuron […]
- Neurofilaments in progressive multiple sclerosis: a systematic review.
Neurofilament proteins have been extensively studied in relapsing-remitting multiple sclerosis, where they […]
- Association between Helicobacter Pylori infection and stroke: a meta-analysis of 273,135 patients.
Stroke stands among the most leading causes of mortality worldwide. Although modifiable […]
- Exergames for balance dysfunction in neurological disability: a meta-analysis with meta-regression.
To evaluate systematically the efficacy of exergames for balance dysfunction in neurological […]
- Visual hallucinations and illusions in Parkinson’s disease: the role of ocular pathology.
Whether different mechanisms, particularly ocular pathology, could lead to the emergence of […]
- Interrelationships among central insulin signalling, diabetes, and cognitive impairment.
Click here to read the full article @ The Lancet. Neurology
- Acrophobia and visual height intolerance: advances in epidemiology and mechanisms.
Historical descriptions of fear at heights date back to Chinese and Roman […]
- A systematic review and meta-analyses of pregnancy and fetal outcomes in women with multiple sclerosis: a contribution from the IMI2 ConcePTION project.
Neurologists managing women with Multiple Sclerosis (MS) need information about the safety […]
- Understanding multifactorial brain changes in type 2 diabetes: a biomarker perspective.
People with type 2 diabetes are at an increased risk of cognitive […]
- A novel frameshift deletion in autosomal recessive SBF1-related syndromic neuropathy with necklace fibres.
To identify the genetic cause of complex neuropathy in two siblings from […]
- A review of seizures and epilepsy following traumatic brain injury.
Traumatic brain injury (TBI) is one of the commonest presentations to emergency […]
- Dopaminergic function in spinocerebellar ataxia type 6 patients with and without parkinsonism.
Although pure cerebellar ataxia is usually emphasized as the characteristic clinical feature […]
- Cognitive functions in acute unilateral vestibular loss.
Cognitive deficits mainly involving visuospatial functions have been defined in patients with […]
- Pick’s disease: clinicopathologic characterization of 21 cases.
Pick’s disease (PiD) is a unique subtype of frontotemporal lobar degeneration characterized […]
- Sonography of optic nerve sheath diameter identifies patients with middle cerebral artery infarction at risk of a malignant course: a pilot prospective observational study.
To assess the value of optic nerve sheath diameter (ONSD) measurements at […]
- DCTN1-related Parkinson-plus disorder (Perry syndrome).
Dynactin-1 (DCTN1)-related Parkinson-plus disorder (Perry syndrome) is an autosomal dominant neurodegenerative disorder […]
- How to diagnose difficult white matter disorders.
Genetic and acquired disorders of white matter comprise a diverse group of […]
- An update on MSA: premotor and non-motor features open a window of opportunities for early diagnosis and intervention.
In this review, we describe the wide clinical spectrum of features that […]
- When does postural instability appear in monogenic parkinsonisms? An individual-patient meta-analysis.
Postural instability is a disease milestone signaling advanced disease.To estimate the onset […]
- Expansion of the dimensions in the current management of acute ischemic stroke.
Stroke is the fifth leading cause of death in the United States […]
- Diagnostic and therapeutic aspects of hemiplegic migraine.
Hemiplegic migraine (HM) is a clinically and genetically heterogeneous condition with attacks […]
- Myelin oligodendrocyte glycoprotein-associated disorders are associated with HLA subtypes in a Chinese paediatric-onset cohort.
Myelin oligodendrocyte glycoprotein-associated disorders (MOGADs) are a rare new neurological autoimmune disease […]
- Self-injurious behaviour in movement disorders: systematic review.
Self-injurious behaviours (SIBs) are defined as deliberate, repetitive and persistent behaviours that […]
- Neurosarcoidosis: clinical manifestations, investigation and treatment.
Sarcoidosis affects the nervous system in 10% of cases. When it does […]
- Impact of environmental factors and physical activity on disability and quality of life in CIDP.
A few observational studies and randomized trials suggest that exercise and rehabilitation […]
- A review of mobile stroke units.
Mobile stroke units (MSUs) for prehospital treatment and management of patients with […]
- Do patients with large vessel occlusion ischemic stroke harboring prestroke disability benefit from thrombectomy?
Evidence of endovascular treatment (EVT) for acute large vessel occlusion (LVO) ischemic […]
- Prevalence and risk factors of silent brain infarcts in patients with AF detected by 3T-MRI.
Silent brain infarcts (SBI), a finding on neuroimaging, are associated with higher […]
- Outcomes of a 5-week individualised MDT outpatient (day-patient) treatment programme for functional neurological symptom disorder (FNSD).
We report results from a 5-week MDT treatment programme, with individualised sessions, […]
- Early ischaemic and haemorrhagic complications after atrial fibrillation-related ischaemic stroke: analysis of the IAC study.
Predictors of long-term ischaemic and haemorrhagic complications in atrial fibrillation (AF) have […]
- Clinical trials in REM sleep behavioural disorder: challenges and opportunities.
The rapid eye movement sleep behavioural disorder (RBD) population is an ideal […]
- CSF lactate.
Lactate is produced from anaerobic glycolysis, which occurs in most tissues in […]
- The contribution of enhancing lesions in monitoring multiple sclerosis treatment: is gadolinium always necessary?
MRI is highly sensitive for monitoring of disease activity and treatment efficacy […]
- Screening for genetic mutations in patients with neuropathy without definite etiology is useful.
To determine the clinical usefulness of systemic genetic testing in neuropathies without […]
- Asymmetry index of Blink Reflex Recovery Cycle differentiates Parkinson’s disease from atypical Parkinsonian syndromes.
Differential diagnosis between Parkinson’s disease (PD) and atypical Parkinsonian syndromes (APS), such […]
- Posterior circulation stroke: machine learning-based detection of early ischemic changes in acute non-contrast CT scans.
Triage of patients with basilar artery occlusion for additional imaging diagnostics, therapy […]
- Gadolinium enhancement on cranial MRI in multiple sclerosis is age dependent.
Epidemiological, pathological and radiological studies suggest that inflammatory demyelination in MS is […]
- Epilepsy in children with leukodystrophies.
Epilepsy might be one of the manifestations in children with leukodystrophies, but […]
- Cerebellar degeneration in adult spinal muscular atrophy patients.
Spinal muscular atrophy (SMA) is a genetic motor neuron disease related to […]
- Ioflupane 123I (DAT scan) SPECT identifies dopamine receptor dysfunction early in the disease course in progressive apraxia of speech.
To describe 123I-FP-CIT (DAT scan) SPECT findings in progressive apraxia of speech […]
- Neurofilament light chain as a potential biomarker of disease status in Friedreich ataxia.
The present study evaluates serum neurofilament light chain (NfL) as a biomarker […]
- Application of “Mentzer’s PML case definition” to natalizumab-treated patients in the setting of strict MRI-based pharmacovigilance.
To compare the available diagnostic criteria for progressive multifocal leukoencephalopathy (PML) diagnosis […]
- New insights in post-traumatic headache with cluster headache phenotype: a cohort study.
To define the characteristics of post-traumatic headache with cluster headache phenotype (PTH-CH) […]
- Distinct dopaminergic abnormalities in traumatic brain injury and Parkinson’s disease.
Traumatic brain injury (TBI) and rapid eye movement sleep behavioural disorder (RBD) […]
- Overlapping syndrome of MOG-IgG-associated disease and autoimmune GFAP astrocytopathy.
Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been considered to be closely […]
- Progression of grey and white matter brain damage in Parkinson’s disease: a critical review of structural MRI literature.
The current review summarizes the current knowledge on longitudinal cortical and subcortical […]
- Advantages of timing the duration of a freezing of gait-provoking test in individuals with Parkinson’s disease.
Evaluating freezing of gait (FOG) and quantifying its severity in patients with […]
- A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid β-amyloid42, total-tau, phospho-tau and α-synuclein in the differential diagnosis of neurodegenerative dementia.
Differential diagnosis of neurodegenerative dementia is currently supported by biomarkers including cerebrospinal […]
- Lumboperitoneal shunt in idiopathic normal pressure hydrocephalus: a prospective controlled study.
In this prospective, controlled, monocentric study, we described the clinical and neuroimaging […]
- Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis.
To determine the prevalence of antibodies to Epstein-Barr virus (EBV) in a […]
- A prospective, controlled study of non-motor effects of subthalamic stimulation in Parkinson’s disease: results at the 36-month follow-up.
To examine 36-month effects of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) […]
- Hypoglossal palsy from an atlanto-axial synovial cyst.
Click here to read the full article @ Practical neurology
- Longitudinal medication profile and cost savings in Parkinson’s disease patients after bilateral subthalamic nucleus deep brain stimulation.
Deep brain stimulation of the subthalamic nucleus (STN DBS) has been shown […]
- Exome sequencing in 38 patients with intracranial aneurysms and subarachnoid hemorrhage.
Genetic risk factors for unruptured intracranial aneurysms (UIA) and aneurysmal subarachnoid hemorrhage […]
- Persistent asymptomatic or mild symptomatic hyperCKemia due to mutations in ANO5: the mildest end of the anoctaminopathies spectrum.
The ANO5 gene encodes for anoctamin-5, a chloride channel involved in muscle […]
- Familial Creutzfeldt-Jakob disease homozygous to the E200K mutation: clinical characteristics and disease course.
To characterize the demographic, clinical features and disease course of familial Creutzfeldt-Jakob […]
- A nerve conduction study predicts the prognosis of sporadic amyotrophic lateral sclerosis.
To clarify the relationship between nerve conduction study (NCS) and prognosis in […]
- Whole-body muscle MRI of patients with MATR3-associated distal myopathy reveals a distinct pattern of muscular involvement and highlights the value of whole-body examination.
MATR3-associated distal myopathy is a rare distal myopathy predominantly affecting lower legs […]
- Treatment expectations and patient-reported outcomes of nusinersen therapy in adult spinal muscular atrophy.
The antisense-oligonucleotide (ASO) nusinersen has recently been approved as the first genetically […]
- The IN-DEEP project “INtegrating and Deriving Evidence, Experiences, Preferences”: a web information model on magnetic resonance imaging for people with multiple sclerosis.
The IN-DEEP project aims to provide people with multiple sclerosis (PwMS) with […]