The Latest Maternal & Fetal Medicine

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Keep up to date with the latest in maternal & fetal medicine . Check out the latest maternal & fetal medicine articles from leading medical journals in a single view, helping you discover relevant articles quickly and easily

  • Society for Maternal-Fetal Medicine (SMFM) Consult Series #53: Intrahepatic Cholestasis of Pregnancy.
    Intrahepatic cholestasis of pregnancy is a hepatic disorder characterized by pruritus and an elevation in serum bile acid concentrations. While intrahepatic cholestasis of pregnancy poses little risk for mothers, this condition carries significant risk for the fetus, including complications such as prematurity, meconium-stained amniotic fluid, and stillbirth. The purpose of this Consult is to review […]
  • Placental energy metabolism in health and disease – significance of development and implications for preeclampsia.
    The placenta is a highly metabolically active organ fulfilling the bioenergetic and biosynthetic needs to support its own rapid growth and that of the fetus. Placental metabolic dysfunction is a common occurrence in preeclampsia although its causal relationship to the pathophysiology is unclear. At the outset, this may simply be seen as an “engine out […]
  • The association between threatened preterm labour and perinatal outcomes at term: a population-based cohort study.
    To estimate the association between threatened preterm labour (TPTL) and perinatal outcomes of infants born at term.A population-based cohort study of perinatal outcomes following TPTL < 37 weeks’ gestation with delivery at term.Nova Scotia, Canada POPULATION: All non-anomalous, singleton pregnancies ≥ 37 weeks’ gestation without antepartum hemorrhage from 1988 to 2019.Using data from the Nova […]
  • Impact of new definitions of preeclampsia at term on identification of adverse maternal and perinatal outcomes.
    To investigate the ability of the American College of Obstetricians and Gynecologists (ACOG) and International Society for the Study of Hypertension in Pregnancy (ISSHP) definitions of preeclampsia at term gestational age (≥37+0 weeks), to identify adverse maternal and perinatal outcomes.In this prospective cohort study at two maternity hospitals in England, women attending a routine hospital […]
  • Private Equity Investments in Women’s Health and Obstetrics and Gynecology Practices.
    Private equity has evolved into a major force in health care, with deal values and volumes rising year-over-year as these firms purchase hospital systems and physician groups. Historically, these investors have played an outsized role in highly reimbursed specialties such as dermatology and anesthesia. Private equity is relatively new to women’s health; when it has […]
  • Hospital-Level Variation in the Frequency of Cesarean Delivery Among Nulliparous Women Who Undergo Labor Induction.
    To evaluate the use of administrative data for identification of labor induction and to estimate the variation in cesarean delivery rates among low-risk women who underwent labor induction.A cross-sectional study was performed examining live births in California hospitals during 2016 and 2017 using birth certificate data linked with maternal patient discharge records. Initially, eight hospitals […]
  • Evaluating the Association of Stillbirths After Maternal Vaccination in the Vaccine Safety Datalink.
    To evaluate whether the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices recommended influenza and tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccinations in pregnancy are associated with increased risk of stillbirth.We performed a case-control study in the Vaccine Safety Datalink that was matched 1:4 on site, month, and year […]
  • Prevalence of Home Births and Associated Risk Profile and Maternal Characteristics, 2016-2018.
    To estimate the prevalence of pregnancies that meet the low-risk criteria for planned home births and describe geographic and maternal characteristics of home births compared with hospital births.Data from the 2016-2018 Pregnancy Risk Assessment Monitoring System (PRAMS), a survey among women with recent live births, and linked birth certificate variables were used to calculate the […]
  • Characteristics of Stillbirths Associated With Diabetes in a Diverse U.S. Cohort.
    To characterize stillbirths associated with pregestational diabetes and gestational diabetes mellitus (GDM) in a large, prospective, U.S. case-control study.A secondary analysis of stillbirths among patients enrolled in a prospective; multisite; geographically, racially, and ethnically diverse case-control study in the United States was performed. Singleton gestations with complete information regarding diabetes status and with a complete […]
  • Perinatal outcomes in women with elevated blood pressure and stage 1 hypertension.
    Hypertension was redefined in 2017 with lower diagnostic thresholds; elevated blood pressure is defined as systolic blood pressure 120-129 mm Hg with diastolic blood pressure <80 mm Hg and stage 1 hypertension as systolic blood pressure 130-139 mm Hg and/or diastolic blood pressure 80-89 mm Hg. These guidelines did not include pregnant women. There is […]
  • Spontaneous preterm birth following second stage caesarean.
    Worldwide, preterm birth occurs in 11% of pregnancies and is the leading cause of childhood mortality (Int J Gynaecol Obstet 2020; 150:31-3). Complications from preterm birth are the most common cause of neonatal death in the United Kingdom, yet the incidence of preterm birth is not falling. View the full article @ BJOG : an […]
  • Cesarean Delivery and Gender of Delivering Physicians: A Systematic Review and Meta-analysis.
    To assess the association of the gender of the delivering physician and the odds of performing cesarean delivery.CINAHL, ClinicalTrials.gov, Cochrane Library, PubMed, Scopus and Web of Science from the first year of records through May 2020.We included studies that reported odds ratios (OR), or data allowing the calculation of ORs, for cesarean delivery performed by […]
  • Rethinking Prenatal Screening for Anomalies of Placental and Umbilical Cord Implantation.
    The most common anomalies of implantation of the placenta and umbilical cord include placenta previa, placenta accreta spectrum, and vasa previa, and are associated with considerable perinatal and maternal morbidity and mortality. There is moderate quality evidence that prenatal diagnosis of these conditions improves perinatal outcomes and the performance of ultrasound imaging in diagnosing them […]
  • The effects of a combined intervention (DHA supplementation and home-based dietary counseling) on metabolic control in obese and overweight pregnant women: the MIGHT study.
    Lifestyle interventions have shown limited effectiveness in the prevention of gestational diabetes mellitus (GDM). The combination of lifestyle interventions with omega-3 polyunsaturated fatty acid (PUFA) supplementation could have a synergetic effect on maternal and offspring outcomes. This joint intervention has not been previously evaluated.We evaluated the effects of docosahexaenoic acid (DHA) supplementation among obese and […]
  • Systematic classification of maternal and fetal intervention related complications following open fetal myelomeningocele repair – results from a large prospective cohort.
    To systematically categorize all maternal and fetal intervention related complications after open fetal myelomeningocele (fMMC) repair of the first 124 cases operated at the Zurich Center for Fetal Diagnosis and Therapy.A prospective cohort study SETTING: Single center POPULATION: Mothers and fetuses after fMMC repair METHODS: Between 2010 and 2019, we collected and entered all maternal […]
  • Embryo Biopsy and Perinatal Outcomes for Singletons: An analysis of 16,246 frozen embryo transfer cycles reported in SART CORS.
    Preimplantation genetic testing (PGT) is commonly performed by removal of cells from the trophectoderm, the outer layer of the blastocyst which will give rise to the placenta. Because PGT removes cells that are destined to form the placenta, it is possible that PGT could be associated with increased risk of adverse outcomes associated with abnormal […]
  • Routine first-trimester ultrasound screening using a standardized anatomical protocol.
    First trimester ultrasound scans were introduced to China for nearly 20 years. The ability of first-trimester ultrasound screening to detect different malformations was variable. A recent systematic review concluded that the use of a standardized anatomical protocol was the most crucial factor to improve the sensitivity of first-trimester ultrasound screening for anomalies. Standardized sectional scans […]
  • Prenatal chromosomal microarray analysis in 2466 fetuses with ultrasonographic soft markers: a prospective cohort study.
    Soft markers are nonspecific findings detected by ultrasonography during the second trimester, that are often transient and nonpathological but may imply an increased risk for underlying fetal aneuploidy. However, large-scale prospectively stratified studies focusing on the prevalence of chromosomal aberrations, including copy number variants, in fetuses with different types of isolated soft markers have rarely […]
  • The long-term effect of prenatal progesterone treatment on child development, behaviour and health: a systematic review.
    Progesterone is widely used in prenatal care. However, long-term effects of prenatal progesterone treatment on child development are unclear.To evaluate long-term outcomes in children after prenatal progesterone treatment.MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials from inception to 24 May 2020.Randomized controlled trials (RCTs) reporting outcomes in children born to women who received progesterone […]
  • Conceptual controversies regarding the terms Gender and Sex.
    I have been following lately the debate that has emerged in the Greek and International literature regarding the terms “sex” and “gender”. Traditionally, the term sex refers to the assignment of gender at birth by the obstetrician or the midwife, based on the external genitalia. They declared the sex of the newly born baby as […]
  • New-Onset myocardial injury in COVID-19 Pregnant Patients: A Case Series of 15 Patients.
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the new coronavirus responsible for the coronavirus disease (COVID-19), characterized by acute respiratory distress syndrome and atypical pneumonia. In non-pregnant women, studies have shown that SARS-CoV-2 causes cardiac injury, which can result in myocardial inflammation and damage. Despite many studies investigating the extent of cardiac compromise in […]
  • PREDICTION OF OBSTETRIC AND FETAL COMPLICATIONS USING AUTOMATED ELECTRONIC HEALTH RECORD DATA.
    Increasing numbers of delivering women experience major morbidity and mortality. Limited work has been done on automated predictive models that could be used for prevention.Using only routinely collected obstetric data, we aimed to develop a predictive model suitable for real time use with an electronic medical record.We employed a retrospective cohort study design with split […]
  • Gynecologic Considerations for Adolescents and Young Women With Cardiac Conditions: ACOG Committee Opinion Summary, Number 813.
    Congenital heart conditions are the most common type of congenital anomaly, affecting nearly 1% of U.S. births, or approximately 40,000 neonates, each year. As more female patients with congenital heart disease enter adolescence and adulthood, there is a growing need to address reproductive health in this population. Addressing contraceptive needs is particularly important for adolescents […]
  • Gynecologic Considerations for Adolescents and Young Women With Cardiac Conditions: ACOG Committee Opinion, Number 813.
    Congenital heart conditions are the most common type of congenital anomaly, affecting nearly 1% of U.S. births, or approximately 40,000 neonates, each year. As more female patients with congenital heart disease enter adolescence and adulthood, there is a growing need to address reproductive health in this population. Addressing contraceptive needs is particularly important for adolescents […]
  • Antenatal Dexamethasone for Early Preterm Birth in Low-Resource Countries.
    The safety and efficacy of antenatal glucocorticoids in women in low-resource countries who are at risk for preterm birth are uncertain.We conducted a multicountry, randomized trial involving pregnant women between 26 weeks 0 days and 33 weeks 6 days of gestation who were at risk for preterm birth. The participants were assigned to intramuscular dexamethasone […]
  • IMBALANCES IN CIRCULATING ANGIOGENIC FACTORS IN THE PATHOPHYSIOLOGY OF PREECLAMPSIA AND RELATED DISORDERS.
    Preeclampsia is a devastating medical complication of pregnancy that can lead to significant maternal and fetal morbidity and mortality. It is currently believed that there is abnormal placentation as early as the first trimester in women destined to develop preeclampsia. While the etiology of the abnormal placentation is being debated, numerous epidemiological and experimental studies […]
  • Predicting severe cardiovascular morbidity in pregnancy and beyond.
    As the provision of care improves across the globe, severe maternal morbidity (SMM) is replacing maternal mortality as the indicator-of-choice for monitoring improvement in the quality of maternity care. Often inadequately defined and poorly captured, SMM results in considerable short and long-term consequences to families and major implications to healthcare systems. View the full article […]
  • The placental prophecy: predicting future maternal CVD.
    Cardiovascular disease (CVD) is commonly seen as a male affliction and thus the majority of research has been into the male disease. More recently it is understood that women not only have higher relative risk of CVD, but that the disease progression and symptoms are different in females to males (Möller-Leimkühler, Dialogues Clin Neurosci 2007; […]
  • Multidrug-resistant tuberculosis during pregnancy and adverse birth outcomes: a systematic review and meta-analysis.
    Multidrug-resistant tuberculosis (MDR-TB) is a major global public health concern. However, there is a dearth of literature on whether MDR-TB and its medications impact maternal and perinatal outcomes, and when such evidence exists the findings are conflicting.This systematic review and meta-analysis aimed to examine the impact of MDR-TB and its medications during pregnancy on maternal […]
  • Caesarean birth and risk of subsequent preterm birth: a retrospective cohort study.
    To determine the risk of spontaneous and medically indicated preterm birth associated with mode of birth in previous term born pregnancy.Retrospective cohort study SETTING: Two UK maternity units POPULATION OR SAMPLE: 16340 women with first two consecutive singleton births and the first birth at term METHODS: Retrospective cohort study using routinely collected clinical data.Incidence of […]
  • Chikungunya Infection in Pregnancy- Reassuring Maternal and Perinatal Outcomes: A Retrospective Observational Study.
    To evaluate pregnancy and neonatal outcomes, disease severity, and mother-to-child transmission of pregnant women with Chikungunya infection (CHIKV).Retrospective observational study.Grenada.Women who gave birth during a Chikungunya outbreak between January 2014 to September 2015 were eligible.This descriptive study investigated 731 mother-infant pairs who gave birth during a CHIKV outbreak. Women and infants underwent serologic testing for […]
  • The Gynecologic Exam of the Transfeminine Person Following Penile Inversion Vaginoplasty.
    As more transfeminine patients (transgender and gender diverse persons, sex assigned male at birth, who identify on the feminine spectrum of gender) are undergoing gender-affirming penile inversion vaginoplasty, gynecologists, as providers of vaginal care for both native and neovaginas, should be prepared to welcome these patients into their practice and offer long term pelvic health […]
  • Patient and Provider Perspectives of a New Prenatal Care Model Introduced in Response to the COVID-19 Pandemic.
    Randomized controlled trials document the safety and efficacy of reduced frequency prenatal visit schedules and virtual visits, but real-world data are lacking. Our institution created a prenatal care delivery model incorporating these alternative approaches to continue safely providing prenatal care during the COVID-19 pandemic. Our objective was to evaluate institutional-level adoption and patient and provider […]
  • Fetal descent in nulliparous women assessed by ultrasound: a longitudinal study.
    Ultrasound offers objective and reproducible methods to measure fetal head station. Before these methods can be applied to assess labor progress, fetal head descent needs to be evaluated longitudinally in well-defined populations and compared to existing data derived from clinical examinations.We aimed to use ultrasound measurements to describe fetal head descent longitudinally as labor progressed […]
  • Intra-partum care of the perineum matters: new knowledge and remaining gaps.
    The prevalence of obstetric anal sphincter injuries (OASIS) varies between hospitals and countries from rates below 1% to over 5%. In Europe there is a North – South gradient (Blondel et al, Acta Obstet Gynecol Scand. 2016; 95:746-54). Variations of prevalence are reported to be related to three factors: (i) insufficient diagnosis in very low […]
  • A Chronicle of the 17OHP-C Story to Prevent Recurrent Preterm Birth.
    Preterm birth is a substantial public health concern. In 2019, the United States preterm birth rate was 10.23%, which is the fifth straight year of increase in this rate. Moreover, preterm birth accounts for approximately one-in-six infant deaths, and surviving children often suffer developmental delay or long-term neurologic impairment. While the burden of preterm birth […]
  • Birth Behind Bars: The Need for Labor Support in the Incarcerated Population.
    The population of women within carceral systems is growing rapidly. A portion of these individuals are pregnant and will deliver while incarcerated. Although shackling laws for pregnant persons have improved, incarcerated patients are forced to labor without the support of anyone but a carceral officer and their medical staff. We believe access to continuous labor […]
  • Management of Postpartum Hemorrhage With a Mini-Sponge Tamponade Device.
    Postpartum hemorrhage is a leading cause of maternal mortality globally. A tamponade agent that can be quickly and easily placed in a range of settings could advance the treatment of atonic hemorrhage.We adapted a highly effective trauma dressing for use in postpartum hemorrhage. This mini-sponge tamponade device is comprised of two components: compressed mini-sponges contained […]
  • Associations Between Comorbidities and Severe Maternal Morbidity.
    To evaluate the associations between the number of chronic conditions and maternal race and ethnicity (race) with the risk of severe maternal morbidity.Using the National Inpatient Sample, Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality, years 2016-2017, we examined risk of severe maternal morbidity among 1,480,925 delivery hospitalizations among women of different […]
  • Detection and Prevention of Postpartum Posttraumatic Stress Disorder: A Call to Action.
    The rising maternal mortality rate has drawn increased focus to postpartum depression. However, other mental health conditions, such as birth-related postpartum traumatic stress disorder, have not garnered the same level of attention. The majority of research about postpartum posttraumatic stress disorder (PTSD) is published in journals focused on psychiatry, psychology, and nursing, where this phenomenon […]
  • Foley Bulb Added to an Oral Misoprostol Induction Protocol: A Cluster Randomized Trial.
    To evaluate whether the induction of labor in term gravid women with cervical dilation 2 cm or less and intact membranes by using oral misoprostol preceded by transcervical Foley bulb placement results in a significantly increased vaginal delivery rate compared with the use of oral misoprostol alone.We randomized the induction method by week of admission […]
  • Vaginal Delivery After External Cephalic Version in Patients With a Previous Cesarean Delivery: A Systematic Review and Meta-analysis.
    To estimate the rate of vaginal delivery after successful external cephalic version for breech presentation in women with compared with without a previous cesarean birth.We searched MEDLINE, Scopus, EMBASE, CINAHL, ClinicalTrials.gov, and Cochrane Central Register of Controlled Trials for studies comparing the mode of delivery after successful external cephalic version in women with and without […]
  • Pregnancy, puerperium and perinatal constipation – an observational hybrid survey on pregnant and postpartum women and their age-matched non-pregnant controls.
    To evaluate the prevalence of constipation during pregnancy and early puerperium.Observational survey.Secondary and tertiary hospital in Finland.Pregnant (N=474) and postpartum (N=403) women and a control group of 200 non-pregnant women who did not give birth within a past year.Women reported bowel function and other gastrointestinal symptoms with a structured questionnaire using 11-point numerical rating scale […]
  • The effect of polycystic ovary syndrome (PCOS) without hyperandrogenism on pregnancy-related outcomes: a retrospective cohort study.
    To evaluate the effect of polycystic ovary syndrome (PCOS) without hyperandrogenism on pregnancy-related outcomes.A retrospective cohort study SETTING: Reproductive Medicine Center of Tongji Hospital POPULATION: Patients without hyperandrogenism undergoing their first single blastocyst transfers in frozen-thawed cycles were divided into the PCOS group and the non-PCOS group according to the Rotterdam criteria.The pregnancy-related outcomes of […]
  • Incidence and associated predictors of adverse pregnancy outcomes of maternal syphilis in China, 2016-2019: a cox regression analysis.
    This study aimed to investigate the incidence and associated predictors of adverse pregnancy outcomes (APOs) among pregnant women infected with syphilis.Cox regression analysis.China.Pregnant women who were tested and diagnosed with syphilis during the index pregnancy and delivered at a gestational age ≥28 weeks between 2016 and 2019.Data were extracted from China’s Information System of Prevention […]
  • Detection of SARS-CoV-2 in vaginal swabs of women with acute SARS-CoV-2 infection: a prospective study.
    To determine whether SARS-CoV-2 is present in the vaginal secretions of both reproductive-aged and postmenopausal women during acute SARS-CoV-2 infection.Prospective study.a single tertiary, university-affiliated medical center in Israel. Time period, June 1, 2020 through July 31, 2020.Women that were hospitalized in a single tertiary medical center, who were diagnosed with acute SARS-CoV-2 infection by a […]
  • Planned Oocyte Cryopreservation (Planned OC): Systematic Review and Meta-analysis of Cost-Efficiency and Patients’ perspective.
    Advances in vitrification techniques have enabled planned oocyte cryopreservation (‘Planned OC’).To explore the cost-efficiency and utilization of planned OC, as well as patients’ perspectives on the process.A systematic search in PubMed/MEDLINE, EMBASE, Cochrane Database and PsychINFO, for all relevant studies published between Jan 2007-Dec 2019.The protocol followed PRISMA guidelines in PECO format, and was registered […]
  • Improved stillbirth risk stratification, an urgent global need.
    Stillbirth is among the most devastating pregnancy complications and is also one of the hardest complications to predict. Traditionally, stillbirth risk stratification has incorporated maternal demographic characteristics such as age and ethnicity as well as medical and pregnancy conditions including multiple gestation, chronic hypertension and pregestational diabetes. While these are clear risk factors for stillbirth, […]
  • Management of Clinical Chorioamnionitis: An Evidence-Based Approach.
    The aim of this review was to examine the existing evidence about interventions proposed for the treatment of clinical chorioamnionitis, with the goal of developing an evidence-based contemporary approach for the management of this condition. Most trials that assessed the use of antibiotics in clinical chorioamnionitis included patients with a gestational age ≥34 weeks and […]
  • Decidualization resistance in the origin of preeclampsia.
    Preeclampsia (PE) is a major obstetric complication with short- and long-term life-threatening consequences for both mother and child. Shallow cytotrophoblast (CTB) invasion through the uterine decidua into the spiral arteries is implicated in the pathogenesis of preeclampsia, though the cause of deficient arterial invasion remains unknown. Research focused on the “soil”-the maternal decidua-highlights the importance […]
  • The diagnostic value of angiogenic / anti-angiogenic factors in differential diagnosis of preeclampsia.
    The definition of preeclampsia is changing. However, with the addition of organ symptoms to the presence of hypertension in pregnancy instead of relying only on proteinuria, a more precise detection of women at risk for preeclampsia-associated adverse events has not been achieved. Instead, under the new definitions of the American College of Obstetricians and Gynecologists […]
  • PREVIOUS PRETERM CESAREAN DELIVERY AND RISK OF UTERINE RUPTURE IN SUBSEQUENT TRIAL OF LABOR.
    Previous cesarean delivery is the major risk factor for uterine rupture in subsequent trial of labor. It has been suggested that a previous preterm cesarean delivery is associated with an increased risk of uterine rupture compared with a previous term cesarean delivery. Yet, the proposed association has only been investigated in a few studies and […]
  • Associations between Social and Behavioural Factors and the risk of Late Stillbirth – Findings from the Midland and North of England Stillbirth Case-Control Study.
    To investigate behavioural and social characteristics of women who experienced a late stillbirth compared to women with ongoing live pregnancies at similar gestation.Case-control study.41 maternity units in the United Kingdom.Women who had a stillbirth ≥28 weeks’ gestation (n=287) and women with an ongoing pregnancy at the time of interview (n=714).Data were collected using an interviewer-administered […]
  • Parity-related variation in cortisol concentrations in hair during pregnancy and in the postpartum period: a prospective cohort study.
    To investigate hair cortisol concentrations (HCC) monthly in pregnant women and to explore the effect of parity.Prospective cohort study from gestational week (GW) 26, at childbirth and postpartum.An antenatal care clinic in southeast Sweden.390 pregnant women.Cortisol was measured using radioimmunoassay in methanol extracts of ground hair samples.Hair cortisol concentrations RESULTS: Both primi- and multiparae exhibited […]
  • Abortion experiences and preferences of transgender, nonbinary, and gender-expansive people in the United States.
    Transgender, nonbinary, and gender-expansive (TGE) people who were assigned female or intersex at birth experience pregnancy and have abortions. No data have been published on individual abortion experiences or preferences of this understudied population.To fill existing evidence gaps on the abortion experiences and preferences of TGE people in the United States to inform policies and […]
  • A report on the impact of rapid prenatal exome sequencing on the clinical management of 52 ongoing pregnancies; a retrospective review.
    Studies have shown Prenatal Exome Sequencing (PES) improves diagnostic yield in cases of fetal structural malformation. We have retrospectively analysed PES cases from two of the largest fetal medicine centres in the UK to determine the impact of results on management of a pregnancy.A retrospective review of clinical case notes.Two tertiary fetal medicine centres.Pregnancies with […]
  • Controversies in prevention of spontaneous preterm birth in asymptomatic women: an evidence summary and expert opinion.
    Preterm birth prevention is multifaceted and produces many nuanced questions. This review addresses six ‘important clinical questions’ about preterm birth prevention as voted for by members of the UK Preterm Clinical Network. The questions cover the areas of: preterm birth prevention in ‘low-risk’ populations; screening for asymptomatic genital tract infection in women at high-risk of […]
  • Incidence of postpartum hypertension within 2 years of a pregnancy complicated by preeclampsia: a systematic review and meta-analysis.
    Women with a history of hypertensive disorders of pregnancy (HDP) are at increased long-term risk of cardiovascular disease. However, there has been increasing evidence on the same risks in the months following birth.This review aims to estimate the incidence of hypertension in the first two years after HDP.MEDLINE, EMBASE and Cochrane databases were systematically searched […]
  • Eclampsia in the 21st century.
    The reported incidence of eclampsia is 1.6-10 per 10,000 deliveries in developed countries, where as it is 50-151 per 10,000 deliveries in developing countries. In addition, low resource countries have substantially higher rates of maternal and perinatal mortalities and morbidities. This disparity in incidence and pregnancy outcomes maybe related to universal access to prenatal care, […]
  • Pregnancy prolongation for pre-eclampsia: the obvious and the avoidable.
    The paper by Mulder et al. addresses the effect of pregnancy prolongation on maternal and fetal outcomes in women with early-onset pre-eclampsia diagnosed after 24 weeks of gestation (Mulder et al., BJOG 2020 xxxx). They report that pregnancy prolongation – from the time of pre-eclampsia diagnosis to delivery – is associated with improved offspring outcome […]