The Latest Laryngology Medical Journal Articles

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Keep up to date with the latest in laryngology as a sub-specialty of ENT. Check out the latest laryngology articles from leading medical journals in a single view, helping you discover relevant articles quickly and easily.

  • Perceptual Evaluation of Vocal Fold Vibratory Asymmetry.
    Laryngeal vibratory asymmetry occurring with paresis may result in a perceptually normal or abnormal voice. The present study aims to determine the relationships between the degree of vibratory asymmetry, acoustic measures, and perception of sound stimuli.Animal Model of Voice Production, Perceptual Analysis of Voice.In an in vivo canine model of phonation, symmetric and asymmetric laryngeal […]
  • Tracking Changes in Age Distribution of Head and Neck Cancer in the U.S. from 1975-2016.
    Several independent studies report an alarming increase of patients younger than 40 being diagnosed with squamous cell carcinoma. There is currently a lack of available data clearly tracking changes in the age distribution of head and neck cancer (HNC) within the U.S. This study attempts to elucidate any trends in oral cavity, oropharynx, larynx and […]
  • Thyroarytenoid Muscle Gene Expression in a Rat Model of Early-Onset Parkinson’s Disease.
    Voice disorders in Parkinson’s disease (PD) are early-onset, manifest in the preclinical stages of the disease, and negatively impact quality of life. The complete loss of function in the PTEN-induced kinase 1 gene (Pink1) causes a genetic form of early-onset, autosomal recessive PD. Modeled after the human inherited mutation, the Pink1-/- rat demonstrates significant cranial […]
  • Outcomes of a Postoperative Data-Extraction Questionnaire After Adenotonsillectomy in Children.
    To evaluate outcomes of a postoperative telephone questionnaire for children who underwent adenotonsillectomy (T&A). To determine whether episodes of postoperative hemorrhage were not captured until the call, and whether this impacted knowledge of physician rates of hemorrhage.Retrospective database analysis.Retrospective analysis of outcomes of an 11-question data extraction tool utilized at a tertiary care children’s hospital […]
  • Bilateral Vocal Fold Granuloma and Anterior Glottic Web After Papilloma Excision.
    We present a case of delayed vocal process granulomas and anterior glottic web after treatment of vocal fold papillomas with a laryngeal microdebrider and CO2 laser ablation. This case highlights a risk of vocal fold granuloma in the setting of recurrent respiratory papillomatosis and microdebrider use, warranting close follow-up and consideration of prophylactic voice therapy, […]
  • A Comparison of an Artificial Intelligence Tool to Fundamental Frequency as an Outcome Measure in People Seeking a More Feminine Voice.
    An artificial intelligence (AI) tool was developed using audio clips of cis-male and cis-female voices based on spectral analysis to assess %probability of a voice being perceived as female (%Prob♀). This program was validated with 92% accuracy in cisgender speakers. The aim of the study was to assess the relationship of fo on %Prob♀ by […]
  • Intubation-Related Laryngeal Deficiency and Vocal Fold Immobility in Pediatric Premature Patients.
    We report a posterior laryngeal rating system and measures of voice disability in pediatric patients undergoing phonosurgery for vocal fold paralysis. Posterior glottic deficiency may account for persistent voice disability.Retrospective Study.Retrospective analyses of 66 subjects with primary unilateral vocal fold paralysis were reviewed for the status of posterior glottis and voice disability (Pediatric Voice Handicap […]
  • Speech Characteristics and Oromyofunctional Outcomes in Two Bimaxillary Face Transplantation Patients in Helsinki.
    Facial functional restoration is one of the main goals in face transplantation. We report the oromyofacial function outcomes of two bimaxillary face transplantation (FT) patients in Helsinki.Outcome Study.Two male patients, aged 34 and 59, had severe functional facial disabilities following self-inflicted gunshot injuries sustained to their mid and lower faces several years earlier. Both underwent […]
  • Subjective voice analysis in patients with muscular tension dysphonia: comparison between clinician and patient evaluation.
    This study evaluated the correlation between patient and clinician subjective voice analysis in a group of patients suffering from muscular tension dysphonia. This disease does not usually present with organic lesions, and voice analysis is crucial to evaluate it.A retrospective study with 75 patients was performed. Correlation between grade, roughness, breathiness, asthenia and strain scale […]
  • Serum Hypoxia Inducible Factor-2: A Candidate Prognostic Biomarker for Laryngeal Cancer.
    To determine the serum hypoxia inducible factor-1, -2 and -3 (HIF-1, -2 and -3) levels in patients with laryngeal neoplasm, and to investigate their role in differential diagnosis, prediction of tumor characteristic and extension, and prognosis and survival.Prospective, cohort study at a tertiary referral center.The study was conducted in a tertiary medical centre.Patients with benign, […]
  • Applicability of Selective Electrical Surface Stimulation in Unilateral Vocal Fold Paralysis.
    Selective electrical surface stimulation (SES) of the larynx is not yet routinely considered therapy option in treatment of unilateral vocal fold paralysis (UVFP). Goal of this monocentric feasibility study was to provide systematic data on applicability of SES of intrinsic laryngeal muscles in UVFP under consideration of sensitivity and discomfort thresholds and nonselective side effects.Thirty-two […]
  • Objective Evaluation of Biomaterial Effects after Injection Laryngoplasty- Introduction of Artificial Intelligence-Based Ultrasonic Image Analysis.
    Hyaluronic acid (HA) can be degraded over time. However, persistence of the effects after injection laryngoplasty (IL) for unilateral vocal fold paralysis (UVFP), longer than expected from HA longevity, has been observed. The purpose of the study was to develop an methodology with clinical utility for objective evaluation of the temporal change in HA volume […]
  • A Rare Case of Hemoptysis Caused by a Laryngeal Leech.
    The larynx is an uncommon location for live foreign bodies. The leech can reach the glottis during consumption of contaminated water but is usually expelled by an effective cough reflex. Patients present with hoarseness and dysphagia and occasionally with dyspnea or hemoptysis. Endoscopically, a mobile mass is usually noted in the supraglottic area. We present […]
  • Prevalence of Dysphonia in Children with Adenotonsillar Problems and the Impact of Surgery on Voice.
    Adenotonsillar problems might affect the voices of patients with pediatric dysphonia, which is very common. This study aimed to evaluate the prevalence of dysphonia in patients with adenotonsillar problems and to demonstrate the impact of tonsillectomy and adenoidectomy (T & A) on their voice postoperatively.Single-institution retrospective study.Subjects were recruited from those children admitted for the […]
  • Evaluation of the Human Vocal Fold Lamina Propria Development Using Optical Coherence Tomography.
    Identifying distinctive features of the vocal fold (VF) during development could have significant clinical implications for treating voice disorders. This study investigates the structural organization of the VF microanatomy across gender and age groups using optical coherence tomography (OCT).Prospective clinical trial.In vivo OCT images were acquired from 97 patients (58 males and 39 females) aged […]
  • Extended Middle Cranial Fossa Approach for Placement of Auditory Brainstem Implants.
    Traditionally, auditory brainstem implants (ABIs) have been placed via the translabyrinthine or retrosigmoid approaches. In select patients, a modified extended middle cranial fossa (xMCF) approach with tentorial ligation may be advantageous for vestibular schwannoma (VS) resection and auditory rehabilitation. This manuscript describes the application of this modification of the MCF approach for simultaneous VS resection […]
  • Cotton Ball Self-Retraction Technique: A Novel Surgical Method Used During Microflap Dissection.
    Microsurgical removal with a microflap technique via direct laryngoscopy is considered the primary treatment option for vocal cysts. However, the microflap technique is technically difficult and challenging. Therefore, we developed the “cotton ball self-retraction” technique to aid in vocal cyst surgery and reduce the cyst rupture incidence. This study aimed to evaluate the efficacy of […]
  • Endoscopic laryngeal findings in patients undergoing thyroid and parathyroid surgery.
    This study aimed to report the pre- and post-operative laryngeal endoscopic findings in patients referred by non-otolaryngologists who are undergoing thyroid and/or parathyroid surgery, and to determine the number and nature of referrals before and after the release of the clinical practice guideline for improving voice outcomes after thyroid surgery.This retrospective cohort study, conducted at […]
  • Hyoid Bone Syndrome and Dysphonia: Can Throat Pain Affect the Voice?
    To investigate the relationship of throat pain and dysphonia.Prospective cohort study.Forty-five subjects presenting with hyoid bone syndrome (HBS) and dysphonia were asked to rate their pain on a numerical rating scale and complete the 10-item Voice-Related Quality of Life (V-RQOL) questionnaire prior to and at 1-week follow-up after treatment with triamcinolone injection into the attachments […]
  • SARS-CoV-2 Nasopharyngeal Swab as a Foreign Body: A Case Report.
    The SARS-CoV-2 pandemic response utilizes nasopharyngeal swabbing as a prolific testing method for presence of viral RNA. The depth of the swab to the nasopharynx coupled with breakpoints along the shaft leads to a risk for foreign body retention. Here, we present a case of a nasopharyngeal swab that became a retained foreign body during […]
  • Prospective Evaluation of Safety of Singing on Steroids: Testing the Truth of Received Wisdom.
    Performing while on steroids is widely considered to increase risk of vocal injury. This study aims to determine incidence and type of injury, and changes in performers’ voices after treatment of vocal fold edema (VFE) with glucocorticoids.Prospective Cohort.Fifty-five performers (34 female; 21 male) treated for acute VFE with short-course oral glucocorticoids were prospectively evaluated pre- […]
  • Arytenoid asymmetry: Is it the most predictive parameter for arytenoid adduction in unilateral vocal fold paralysis?
    The aim of this study was to establish arytenoid asymmetry as a pre-operative predictive parameter for arytenoid adduction surgery in unilateral vocal fold paralysis and thereafter identify the most predictive parameter for arytenoid adduction among the established parameters.A retrospective comparative study was undertaken. The ‘arytenoid asymmetry angle’ formed between skewed ‘glottic’ and ‘interarytenoid’ axes (traced […]
  • Combined Transverse Cordotomy- Anteromedial Arytenoidectomy for Isolated Glottic Stenosis.
    Glottic stenosis is a discrete cause of airway compromise. We aimed to determine the surgical outcomes of transverse cordotomy with anteromedial arytenoidectomy (TCAMA), performed in the setting of isolated glottic stenosis resulting from two discrete etiologies: bilateral vocal fold paralysis (BVFP) and posterior glottic stenosis (PGS).Retrospective, analytic cohort study.Twenty-six patients with isolated glottic stenosis were […]
  • Predominant Vertical Location of Benign Vocal Fold Lesions by Sex and Music Genre: Implication for Pathogenesis.
    Vertical locations of vocal fold mucosal lesions (VFMLs) vary along the free edge. As the vertical contact area of vocal folds (VFs) depends on the vocal register, lesions may occur in the contact area of more frequently used vocal registers. This study investigated the cause of location variations by comparing the vertical sites of VFMLs […]
  • Small-Cell Carcinoma of Nasopharynx: A Case Report of Unusual Localization.
    Neuroendocrine tumors are a spectrum of rare and highly heterogeneous neoplasms with distinct functional and biological behavior in relation to location, tumor size, and histological differentiation. Neuroendocrine tumors arise from the neuroendocrine cells of the diffuse neuroendocrine system located in almost every organ. Neuroendocrine tumors in the head and neck district are usually reported in […]
  • Comparison of voice therapy and selective electrical stimulation of the larynx in early unilateral vocal fold paralysis after thyroid surgery: a retrospective data analysis.
    The goal of the retrospective study was to investigate the 3-month-outcome after treatment of patients with early unilateral vocal fold paralysis (UVFP) with either standard voice therapy (VT) or selective electrical stimulation of the larynx (SES).non-randomized retrospective study SETTING: 1519 patients who underwent thyroid surgery between 2015 and 2018 were analyzed according vocal fold mobility; […]
  • Characterization of Functional Dysphonia: Pre- and Post-Treatment Findings.
    Functional dysphonia (FD) is one of the possible presentations of chronic dysphonia. Defined as dysphonia without gross abnormality of the larynx, FD manifests as aberrant muscle contractions resulting in mild-to-severe dysphonia. Despite increasing clinical awareness, diagnosis, and treatment strategies for FD remain challenging.Institutional review board.A retrospective review of videostroboscopic examinations and EMR data from 109 […]
  • Fibrin Gel Suspended Autologous Chondrocytes as Cell-based Material for long-term Injection Laryngoplasty.
    Injection laryngoplasty of materials for unilateral vocal-fold paralysis has shown various results regarding the long-term stability of the injected material. We evaluated a fibrin-gel based cell suspension with autologous chondrocytes in-vitro and in-vivo as long-term-stable vocal-fold augmentation material in an animal model.This study compises an in vitro cell-culture part as well as an in vivo […]
  • A Prospective Study of Voice, Swallow and Airway Outcomes following Tracheostomy for COVID-19.
    The COVID-19 pandemic has led to unprecedented demands on healthcare with many requiring intubation. Tracheostomy insertion has often been delayed and the enduring effects of this on voice, swallow and airway outcomes in COVID-19 tracheostomy patients are unknown. The aim of this study was to prospectively assess these outcomes in this patient cohort following hospital […]
  • Presenting Symptom as a Predictor of Clinical course in Juvenile Onset Recurrent Respiratory Papillomatosis.
    Determine if the presentation of voice versus airway symptoms at the time of diagnosis of juvenile recurrent respiratory papillomatosis (JORRP) correlates with treatment and outcomes.Original report, Retrospective review.Twenty year retrospective review of all patients with JORRP presenting at any time in treatment to a single tertiary children’s hospital between 1997 and 2017.Fifty-four patients presented with […]
  • Maximum vocal intensity as a primary outcome measure in unilateral vocal fold paralysis patients.
    To evaluate voice intensity as the primary outcome measurement when treating unilateral vocal fold paralysis patients.This prospective observational study comprised 34 newly diagnosed unilateral vocal fold paralysis patients undergoing surgical interventions: injection laryngoplasty or medialisation thyroplasty. Voice assessments, including maximum vocal intensity and other acoustic parameters, were performed at baseline and at one and three […]
  • Healthcare Disparities in Laryngology: A Scoping Review.
    This scoping review aims to map out existing disparities research within the subspecialty of laryngology in order to highlight gaps in knowledge and guide future research.Scoping Review.We completed a scoping review of PubMed, Ovid Embase, and the Cochrane Library for primary research focused on evaluating the existence and impact of disparities in race/ethnicity, sex/gender, insurance […]
  • Use of GlideScope in Patients Undergoing NIM Thyroidectomy.
    Thyroidectomy and parathyroidectomy using the nerve integrity monitor (NIM) require proper placement of the endotracheal tube with electrodes aligned correctly within the larynx. The purpose of this study is to determine the percentage of patients who require positional adjustments of the endotracheal tube prior to beginning surgery and to understand the value of using the […]
  • Speech Performance after Anterolateral Thigh Phonatory Tube Reconstruction for Total Laryngectomy.
    Traditionally, after total laryngopharyngectomy (TLP), patients cannot speak without a prosthesis or an artificial larynx. In Taiwan, most patients use a commercialized pneumatic laryngeal device (PLD). Phonatory tube reconstruction with the anterolateral thigh (ALT) flap is a novel, modified version of synchronous digestive and phonatory reconstruction involving a free muscular cutaneous flap. This study reviewed […]
  • Dyspnea Index: An upper airway obstruction instrument; translation and validation in Swedish.
    Upper airway dyspnea is a challenging condition in which assessing the discomfort experienced by the patient is essential. There are three patient-reported outcome (PRO) instruments developed particularly for this patient group, none of which is available in Swedish. The aim of this study was to translate the Dyspnea Index (DI) into Swedish and validate the […]
  • Factors Related to Extralaryngeal Spread in Juvenile Recurrent Respiratory Papillomatosis.
    To identify factors associated to increased risk of extra-laryngeal spread in pediatric patients with recurrent respiratory papillomatosis (RRP).Retrospective chart review.A retrospective study was conducted evaluating the clinical charts of patients younger than 16 years with histopathologically confirmed RRP treated between January 2014 and December 2018. Characteristics of patients with and without extra-laryngeal disease dissemination were compared. […]
  • Laryngeal Pathologies Associated with the Genre of Singing and Professional Singing Status in a Treatment-Seeking Population.
    Singers have high vocal demands and are at increased risk of developing voice disorders. Different singing genres place different technical demands on the voice. However, differences in laryngeal pathology based on genre have not been well-researched. The purpose of this study was to determine the prevalence of laryngeal pathology in different genres of professional and […]
  • IVORY Guidelines (Instructional Videos in Otorhinolaryngology by YO-IFOS): A Consensus on Surgical Videos in Ear, Nose, and Throat.
    Otolaryngology instructional videos available online are often of poor quality. The objective of this article was to establish international consensus recommendations for the production of educational surgical videos in otolaryngology.DELPHI survey.Twenty-seven international respondents participated in this study from 12 countries. Consensus was reached after three rounds of questionnaires following the Delphi methodology. The proposals having […]
  • Perceptual Voice and Speech Analysis after Supraglottic Laryngeal Closure for Chronic Aspiration in Head and Neck Cancer.
    To evaluate the voice and speech outcomes after tubed supraglottic laryngeal closure (TSLC) surgery to treat chronic aspiration after radiotherapy for head and neck cancer.A retrospective case-control study.The data of patients who underwent radiotherapy for head and neck cancer and who later required total laryngectomy or TSLC for chronic aspiration between 2004 and 2017 were […]
  • Factors influencing long-term treatment response to botulinum toxin injection for spasmodic dysphonia.
    The purpose of this study was to evaluate the outcomes of long-term botulinum toxin type A (BoNTA) treatment for adductor spasmodic dysphonia (AdSD) and to determine the factors predictive of treatment response by investigating dose stability and average intervals.Retrospective cohort study.Academic tertiary medical center.A total of 470 patients with adductor spasmodic dysphonia, who received electromyography-guided […]
  • Long-term Swallowing Outcomes of Radiotherapy and Transoral Laser Microsurgery for T1 Glottic Cancer Treatment.
    Both CO2 transoral laser microsurgery (CO2 TOLMS) and radiotherapy (RT) are standard of care in early glottic carcinoma. However, previous studies focus on voice outcomes rather than swallowing outcomes. This study aimed to compare the late post-treatment effects of CO2 TOLMS and RT treatment on swallowing function in T1 glottic carcinoma. View the full article […]
  • Singing voice range profile: new objective evaluation methods for voice change after thyroidectomy.
    After surgery in the thyroid region, patients may present with phonation or singing difficulty, even within their vocal range. We designed a novel voice evaluation method that reflects subjective and objective voice complications of the surgery.This tool recorded patients’ voice ranges while singing, which was named the singing voice range profile (singing VRP). Patients were […]
  • Granulomatous Inflammation Causing Severe Supraglottic Edema and Airway Obstruction in a Pediatric Patient.
    A 12-year-old male with a family history of inflammatory bowel disease presented with sleep-disordered breathing and was found to have chronic, granulomatous swelling of the supraglottic larynx. His airway was managed with tracheostomy, regular interval laryngeal steroid injections, supraglottoplasty, and “pepper pot” CO2 laser resurfacing leading to eventual decannulation. Due to the non-necrotic nature of […]
  • First Description of Alveolar Rhabdomyosarcoma of the Larynx in a Young Child.
    Rhabdomyosarcoma of the larynx has been very rarely described in pediatric population. There are 3 histological subtypes: embryonal, pleomorphic, and alveolar. With regard to the English literature, we present the first case of alveolar rhabdomyosarcoma of the larynx ever described in a child. This tumor has been diagnosed on an endoscopic biopsy. Thus, a unilateral […]
  • Phonation Threshold Pressure/Flow for Reflecting Glottal Closure in Unilateral Vocal Fold Paralysis.
    Previous theoretical analysis predicted that phonation threshold flow (PTF) could be a more sensitive aerodynamic measure than phonation threshold pressure (PTP) for reflecting glottal incompetence. This study investigated the feasibility of whether PTP and PTF may differentiate subjects with unilateral adductor vocal fold paralysis and paresis (UAVFP) from those without, and whether PTP and PTF […]
  • Phonation Threshold Pressure/Flow for Reflecting Glottal Closure in Unilateral Vocal Fold Paralysis.
    Previous theoretical analysis predicted that phonation threshold flow (PTF) could be a more sensitive aerodynamic measure than phonation threshold pressure (PTP) for reflecting glottal incompetence. This study investigated the feasibility of whether PTP and PTF may differentiate subjects with unilateral adductor vocal fold paralysis and paresis (UAVFP) from those without, and whether PTP and PTF […]
  • Crumley’s Classification of Laryngeal Synkinesis: A Comparison of Laryngoscopy and Electromyography.
    Applying the principles of misdirected nerve regeneration to the larynx, Roger Crumley in 1989 coined the term laryngeal synkinesis (LS) which he later (2000) classified into 4 types (type I – good voice, type II – involuntary twitches and poor voice, type III – adduction during inspiration, type IV – abduction during phonation). Neurophysiological data […]
  • Deep Learning for Voice Gender Identification: Proof-of-concept for Gender-Affirming Voice Care.
    The need for gender-affirming voice care has been increasing in the transgender population in the last decade. Currently, objective treatment outcome measurements are lacking to assess the success of these interventions. This study uses neural network models to predict binary gender from short audio samples of “male” and “female” voices. This preliminary work is a […]
  • Clinical Swallowing Profile Change in HNC Patients Treated with C/RT.
    To demonstrate utility of the Mann Assessment of Swallowing Ability-Cancer (MASA-C) to describe change in swallowing ability in a cohort of HNC patients from pre-C/RT to post-C/RT to follow up at 3 months post-C/RT. An exploratory analysis compared patients treated with radiotherapy (RT) only to patients treated with chemoradiation (CRT).Prospective Cohort.The MASA-C and Functional Oral Intake […]
  • Resection of a Giant Hypopharyngeal Liposarcoma Invading the Esophagus by Lateral Pharyngotomy: A Case Report.
    Hypopharyngeal liposarcomas are extremely rare. Due to the lack of experience, pathologists and surgeons find it difficult to make a clear diagnosis and provide accurate, timely treatment. A 43-year-old man with a complaint of foreign body sensation in the throat for 6 months and swallowing difficulty for 2 months was admitted to our department. Contrast-enhanced […]
  • Auditory Feedback Control of Vocal Pitch in Spasmodic Dysphonia.
    Hearing plays an important role in the maintenance of vocal control in normal individuals. In patients with spasmodic dysphonia (SD), however, the ability to maintain sustained control of phonation is impaired. The origins of SD are unknown, and it is unclear whether auditory feedback-dependent vocal control is compromised in these patients.Prospective case-control study.We tested 15 […]
  • Adenoid Cystic Carcinoma of the Larynx: A SEER Database Review.
    Adenoid cystic carcinoma (AdCC) of the larynx is an uncommon malignancy of the head and neck with very little literature discussing treatment paradigms and prognostic factors influencing survival.This retrospective cohort study uses data obtained from the Surveillance, Epidemiology and End Result database comprising of patients diagnosed with laryngeal AdCC from 1978 to 2016.A total of […]
  • Extramedullary Plasmacytoma of False Vocal Cord: Case Report.
    Extramedullary plasmacytoma (EMP) is a malignant tumor formed by monoclonal abnormal proliferation of plasma cells, which is mainly characterized by localized masses and very rare in the larynx, particularly in the false vocal cord. We present a larynx EMP that arises from the false cord without systematic involvement. After surgical resection, the patient received adjuvant […]
  • Predictors of Stricture and Swallowing Function Following Salvage Laryngectomy.
    Long-term functional outcomes are poorly characterized for salvage laryngectomy. We identified predictors of esophageal stricture and swallowing function after salvage laryngectomy in a large cohort.A retrospective study of 233 patients who underwent salvage total laryngectomy for recurrent/persistent squamous cell carcinoma of the larynx or hypopharynx after radiation (XRT) or chemoradiation (CRT) was performed. Primary outcomes […]
  • Voice Component Relationships with High Reflux Symptom Index Scores in Muscle Tension Dysphonia.
    To analyze the Reflux Symptom Index (RSI) and the Voice-Related Quality of Life (V-RQOL) scores based on the perceptual and analytical parameters in primary MTD patients with no reflux.Cross-sectional study.One hundred and eighteen participants, that is, sixty patients with normal voices and fifty-eight patients with primary MTD were recruited in this study. The diagnosis of […]
  • Abnormal Laryngeal Electromyography Findings in Asymptomatic Adults Across the Age Spectrum.
    Laryngeal electromyography (LEMG) is a diagnostic tool for patients with suspected neurogenic abnormalities of the larynx. LEMG is often used with the assumption that any abnormality is symptom-/disease-related. We sought to determine the prevalence of abnormal LEMG findings in a group of healthy asymptomatic adults across a large age spectrum.Open, prospective study, gender-match and age […]
  • Immediate Intraoperative Repair of the Recurrent Laryngeal Nerve in Thyroid Surgery.
    Recurrent laryngeal nerve (RLN) injury is a recognized risk during thyroid and parathyroid surgery and can result in significant morbidity. The aim of this review paper is to consider the optimal approach to the immediate intraoperative repair of the RLN during thyroid surgery.A PubMed literature search was performed from inception to June 2020 using the […]
  • Upper Esophageal Sphincter Response to Laryngeal Adductor Reflex Elicitation in Humans.
    The laryngeal adductor reflex (LAR) is an important mechanism to secure the airways from potential foreign body aspiration. An involvement of the upper esophageal sphincter (UES) in terms of a laryngo-UES contractile reflex has been identified after laryngeal mucosa stimulation. However, the LAR-UES relationship has not yet been fully explained. This study aimed to determine […]
  • Intracordal Injection of Basic Fibroblast Growth Factor in 100 Cases of Vocal Fold Atrophy and Scar.
    Vocal fold atrophy, scar, and sulcus reduce the vibratory function of the vocal fold mucosa, which causes severe refractory dysphonia. We have reported encouraging preliminary results using an intracordal injection of basic fibroblast growth factor (bFGF) and showed improvement in phonatory parameters and voice. The present study summarizes our experience with 100 cases of stiffened […]
  • Parenteral Bevacizumab for the Treatment of Severe Respiratory Papillomatosis in an Adult Population.
    Recurrent respiratory papillomatosis (RRP) is a rare, potentially life-threatening, disease that impacts the voice, breathing, and quality of life of patients. Frequent surgical interventions may be needed to control symptoms. We examined the safety and efficacy of utilizing parenteral bevacizumab in the management of severe RRP in adults.This is a retrospective review of clinical management […]