The Latest COVID-19 & Oncology Journal Articles

Keep up to date with the latest in COVID-19 & oncology. Check out the latest COVID-19 & oncology articles from leading medical journals in a single view, helping you discover relevant articles quickly and easily

• Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2.10th May 2021
  Systemic pools of ATP are elevated in individuals homozygous for cystic fibrosis (CF) as evidenced by elevated blood and plasma ATP levels. This elevated ATP level seems to provide benefit in the presence of advanced solid tumors (Abraham et al., Nature Medicine 2(5):593-596, 1996). We published in this journal a paper showing that IV ATP […]
• ESMO 2020: highlights in breast cancer.10th May 2021
  Despite the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, results of several pertinent studies in the field of breast cancer (BC) were presented in a virtual format at the 2020 European Society of Medical Oncology (ESMO) Congress. Early results of the MonarchE trial investigating the addition of the cyclin-dependent kinase (CDK) 4/6 inhibitor abemaciclib […]
• Impact of anti-cancer therapy on disease severity and mortality in cancer patients with COVID-19: a systematic review and meta-analysis.10th May 2021
  Coronavirus disease-2019 (COVID-19) poses a serious health threat to people around the world, particularly in patients with cancer. Whether or not cancer patients infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) receive anti-cancer therapy is associated with a poor prognosis is unclear. This systematic review and meta-analysis aims to assess whether anti-cancer therapies such as […]
• Robust prediction of mortality of COVID-19 patients based on quantitative, operator-independent, lung CT densitometry.10th May 2021
  To train and validate a predictive model of mortality for hospitalized COVID-19 patients based on lung densitometry.Two-hundred-fifty-one patients with respiratory symptoms underwent CT few days after hospitalization. “Aerated” (AV), “consolidated” (CV) and “intermediate” (IV) lung sub-volumes were quantified by an operator-independent method based on individual HU maximum gradient recognition. AV, CV, IV, CV/AV, IV/AV, and […]
• [Differences of characteristics and outcomes between cancer patients and patients with no active cancer hospitalised for a SARS-CoV-2 infection].10th May 2021
  Patients with solid cancer or haematologic malignancies have been considered to be more susceptible to SARS-CoV-2 infection and to more often develop severe complications. We aimed to compare the differences in clinical features and outcomes of COVID-19 patients with and without cancer.This was a prospective observational cohort study of consecutive adult patients hospitalised in a […]
• A virtual multi-disciplinary meeting is a cost-effective method of triaging referrals to a regional musculoskeletal oncology service.10th May 2021
  In 2010, a virtual sarcoma referral model was implemented, which aims to provide a centralised multidisciplinary team (MDT) to provide rapid advice, avoiding unnecessary appointments and providing a streamlined service. The aim of this study is to examine the feasibility of this screening tool in reducing the service burden and expediting patient journey.All referrals made […]
• Anti-cancer Therapy Leads to Increased Cardiovascular Susceptibility to COVID-19.10th May 2021
  Anti-cancer treatment regimens can lead to both acute- and long-term myocardial injury due to off-target effects. Besides, cancer patients and survivors are severely immunocompromised due to the harsh effect of anti-cancer therapy targeting the bone marrow cells. Cancer patients and survivors can therefore be potentially extremely clinically vulnerable and at risk from infectious diseases. The […]
• COVID-19 vaccine induced Axillary and Pectoral Lymphadenopathy on PET scan.10th May 2021
  Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the ongoing global pandemic. It can manifest a wide range of complications depending upon the severity of infection and comorbidities of the patient. Vaccines are very important measure to provide protection against COVID-19. We report a case of 72-year-old female […]
• Hidden in plain sight: the (other) danger of COVID-19.9th May 2021
  The Novel Coronavirus disease (COVID-19) first emerged in Wuhan province, China, in late November 2019 and changed public healthcare perception. It has caused a significant decline in attendance to outpatient clinics. However, other diseases have not stopped, including malignant melanoma. Survey of the number of visits to plastic surgery outpatient clinic during the first lockdown […]
• Impact of COVID-19 on the outreach strategy of cancer social service agencies in Singapore: A pre-post analysis with Facebook data.9th May 2021
  The Singapore government implemented multiple restrictive measures as the novel coronavirus infection (COVID-19) spread through the community, thereby affecting the support service of cancer-related social service agencies (cancer-SSAs). We are interested to understand how Singapore’s cancer-SSAs utilized the social media platform Facebook to overcome the restrictions which were introduced due to COVID-19. Facebook posts from […]
• Adult preventive vaccines with other synergistic lifestyle options: is it time to add these ancillary benefits to the overall AS management checklist?8th May 2021
  To review the potential ancillary cardiovascular and other health impacts of compliance with general adult vaccination series in the prostate cancer active surveillance (AS) population. No previous review has been published in regard to this specific topic.Literature review of PubMed data up to December 2020 RESULTS: Compliance rates for adult vaccination are in the approximate […]
• Immune profiling of COVID-19: preliminary findings and implications for the pandemic.8th May 2021
  SARS-CoV-2 infection can have widely diverse clinical outcomes, from asymptomatic infection to death, with many possible clinical symptoms and syndromes. It is thus essential to understand how the virus interacts with the host immune system to bring about these varied outcomes and to inform vaccine development. We now know that both antibody and T cell […]
• Impact of the first surge of the COVID-19 pandemic on a tertiary referral centre for kidney cancer.8th May 2021
  To analyse the impact of the COVID-19 pandemic on a centralised specialist kidney cancer care pathway.Retrospective analysis of patient and pathway characteristics including prioritisation strategies at the Specialist Centre for Kidney Cancer (SCKC) located at the Royal Free London NHS Foundation Trust (RFH) before and during the surge of COVID-19.On March 18, 2020 all elective […]
• Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review.7th May 2021
  Coronavirus disease 2019 (COVID-19) is a rapidly emerging disease classified as a pandemic by the World Health Organization (WHO). To support the WHO with their recommendations on quarantine, we conducted a rapid review on the effectiveness of quarantine during severe coronavirus outbreaks.To assess the effects of quarantine (alone or in combination with other measures) of […]
• Safety and efficacy of telephone clinics during the COVID-19 pandemic in the provision of care for patients with cancer.7th May 2021
  Due to the COVID-19 pandemic, telephone clinics have been utilised to reduce the risk of transmission. Evidence supporting its quality and safety is required.Assess the efficacy and safety of telephone clinics in delivering care to established oncology patients and assess patient and health professionals’ preference (telephone vs face-to-face clinics).Retrospective chart audit in the month preceding […]
• Semiqualitative research protocol to explore cancer care workforce perceptions of the health system response to COVID-19 preparations in Southeast Queensland, Australia.7th May 2021
  Sars-CoV-2 is a novel coronavirus responsible for COVID-19 officially declared pandemic in March 2020. Health systems worldwide responded with swift changes to increase workflow capacity while protecting the vulnerable, including those with cancer. This led to unprecedented and rapid restructuring of health service provision. Published data from the 2003 SARS pandemic focuses on medical and […]
• Skin cancers in lockdown: no impact on pathological tumour staging.7th May 2021
  The standard of care for suspected cancer referrals in the National Health Service (NHS) is two weeks from presentation to specialist review.1 National hospital data has shown a 70.4% median reduction in Two Week Wait (TWW) referrals for suspected cancer as a direct result of the COVID-19 pandemic and the national lockdown.2 Colleagues from our […]
• Does systemic anti-tumor therapy increase COVID-19 risk in patients with cancer?7th May 2021
  We aimed to determine the COVID-19 infection rate and determine the factors that affect hospitalization and prognosis in patients receiving systemic chemotherapy (CT), immunotherapy (IT) and molecular-targeted therapies at our hospital within three months after the onset of COVID-19 pandemic.The patients who received systemic treatment at chemotherapy unit with diagnosis of cancer between 11 March […]
• Advanced Stages and Increased Need for Adjuvant Treatments in Breast Cancer Patients: The Effect of the One-year COVID-19 Pandemic.6th May 2021
  The COVID-19 lockdown includes restrictive measures and temporary health system reorganization. Resources were shifted to COVID-19 patients, screening programs were temporary suspended, and oncological care suffered slow-down. The aim of the study was to evaluate the impact of these measures on breast cancer patients.All breast cancer patients referred to our unit from February 21, 2019 […]
• Clinical Characteristics and Outcomes of a Cohort of Pediatric Oncohematologic Patients With COVID-19 Infection in the City of Bogotá, Colombia.6th May 2021
  In children, the complications of severe acute respiratory syndrome coronavirus 2 infection occur less frequently than in adults but the characteristics of this disease in oncology patients are not well characterized.This was a retrospective study in patients younger than 18 years of age with coronavirus disease 2019 (COVID-19) and cancer diagnoses between April and September […]
• Real-Time UV Measurement With a Sun Protection System for Warning Young Adults About Sunburn: Prospective Cohort Study.6th May 2021
  Melanoma is attributable to predisposing phenotypical factors, such as skin that easily sunburns and unprotected exposure to carcinogenic UV radiation. Reducing the proportion of young adults who get sunburned may reduce the incidence of melanoma, a deadly form of skin cancer. Advances in technology have enabled the delivery of real-time UV light exposure and content-relevant […]
• When the World Throws You a Curve Ball: Lessons Learned in Breast Cancer Management.6th May 2021
  In the care of patients with operable breast cancer, there has been a shift toward increasing use of neoadjuvant therapy. There are benefits to neoadjuvant therapy, such as monitoring for response, as well as an increased rate of breast conservation and reduction of potential morbidity associated with breast surgery, including axillary management. Among patients with […]
• How we approach thrombosis risk in children with COVID-19 infection and MIS-C.6th May 2021
  Thrombosis within the microvasculature and medium to large vessels is a serious and common complication among critically ill individuals with coronavirus disease 2019 (COVID-19). While children are markedly less likely to develop severe disease than adults, they remain at risk for thrombosis during acute infection and with the post-acute inflammatory illness termed multisystem inflammatory syndrome […]
• Impact of the COVID-19 Pandemic on Oncology Clinical Research in Latin America (LACOG 0420).6th May 2021
  COVID-19 has affected cancer care worldwide. Clinical trials are an important alternative for the treatment of oncologic patients, especially in Latin America, where trials can be the only opportunity for some of them to access novel and, sometimes, standard treatments.This was a cross-sectional study, in which a 22-question survey regarding the impact of the COVID-19 […]
• Implementation of a palliative hospital-centered spiritual and psychological telehealth system during COVID-19 pandemic.6th May 2021
  The severity of the COVID-19 pandemic has resulted in limited provision of palliative care and hospital teams have had to rise to the challenge of how to deliver care safely to people with palliative needs. Telehealth interventions have been seen as a useful resource with potential to improve clinical effectiveness.To describe the implementation of a […]
• Low dose radiation therapy for severe COVID-19 pneumonia: a randomized double-blind study.6th May 2021
  The morbidity and mortality of patients requiring mechanical ventilation for coronavirus disease 2019 (COVID-19) pneumonia is considerable. We studied the use of whole-lung low dose radiation therapy (LDRT) in this patient cohort.Patients admitted to the intensive care unit (ICU) and requiring mechanical ventilation for COVID-19 pneumonia were included in this randomized double-blind study. Patients were […]
• Mental Health of COVID-19 Patients-A Cross-Sectional Survey in Saudi Arabia.5th May 2021
  Background: This study aims to investigate the mental health of COVID-19 patients in Saudi Arabia. Method: A cross-sectional study was carried out targeting confirmed cases of COVID-19 in Saudi Arabia. Due to travel and time constraints as well as the accessibility of patients, cases were included from East Jeddah Hospital, King Abdulaziz Hospital, and the […]
• Noncommunicable diseases and changes in lifestyles during the COVID-19 pandemic in Brazil.5th May 2021
  To compare lifestyle changes during the COVID-19 pandemic according to the presence or absence of noncommunicable diseases (NCDs) in Brazilian adults.Cross-sectional study, using data from the ConVid survey, between April and May 2020. The following variables were evaluated: lifestyle and presence of one or more NCDs (diabetes, hypertension, respiratory disease, heart disease, and cancer). Sociodemographic […]
• COVID-19 or Not, Breast Cancer Treatment Must Go On.5th May 2021
  When at the end of last year Professor Traian Patrascu asked me to coordinate an issue of the journal “Chirurgia” dedicated to breast cancer, I was both surprised and intrigued. For two reasons: firstly it seemed to me so little time had passed since the previous issue about this disease and perhaps there weren’t many […]
• COVID-19 vaccination and low cervical lymphadenopathy in the two week neck lump clinic – a follow up audit.5th May 2021
  The UK COVID vaccination programme has progressed at an astonishing rate since the first patients received their doses in December 2020. It is well known that other vaccines including influenza and human papilloma virus (HPV) can result in reactive lymphadenopathy in the axilla and/or neck. Patients are now presenting via the two week wait neck […]
• COVID-RO study: the radiation oncology practice at times of COVID-19 outbreak – international survey.5th May 2021
  Radiation therapy (RT), an essential treatment of cancer, involves multiple hospital visits. We hypothesized that radiation departments would adjust their work patterns and RT protocols in response to the SARS-CoV-2 pandemic.An electronic survey was sent during April 2020 to an international sample of radiation oncologists. The survey explored various aspects of departmental preparedness, and changes […]
• Depression and Anxiety Among Patients with Cancer During COVID-19 Pandemic: A Systematic Review and Meta-analysis.5th May 2021
  Investigations about the impact and consequences of the COVID-19 infection on the mental health of patients with chronic diseases and those with immunosuppressive conditions are growing. The current study aimed to systematically review and meta-analysis of studies that evaluated the level of depression and anxiety in cancer patients during the COVID-19 pandemic.The PubMed, Scopus and […]
• Functional Decline as an Indicator of Ill-Health: A Retrospective Case Study of the Process Leading to Lung Cancer.5th May 2021
  Lung cancer claims more lives than any cancer in the world and remains difficult to diagnosis at early stages. Detecting lung cancer is challenging due to nonspecific symptom presentation. Literature was reviewed to consider functional decline as an indicator for ill-health. This study explored the process experienced from recognition in a change of health to […]
• How Has the Occupational Performance and Participation Levels of Children with Cancer Changed during the COVID-19 Pandemic?5th May 2021
  Aim: To examine how the occupational performance (OP) and participation levels of children with cancer changed during the COVID-19 pandemic.Methods: Sixty-seven children with cancer (aged 6-12 years) completed the Canadian Occupational Performance Measure by giving information about their OP and participation, and their parents completed the Child and Adolescent Scale of Participation via online interview techniques. […]
• Immune thrombocytopenia following multisystem inflammatory syndrome in children (MIS-C) – a case series.5th May 2021
  Patients with coronavirus disease 2019 (COVID-19) from novel coronavirus (SARS-CoV-2) infection may present with immune thrombocytopenia (ITP). Multisystem inflammatory syndrome in children (MIS-C) is a serious complication of SARS-CoV-2 causing systemic organ dysfunction. This case series presents the first reported cases of patients who developed ITP following MIS-C, while completing corticosteroid tapers. These patients responded […]
• Cervical screening during the COVID-19 pandemic: optimising recovery strategies.3rd May 2021
  Disruptions to cancer screening services have been experienced in most settings as a consequence of the COVID-19 pandemic. Ideally, programmes would resolve backlogs by temporarily expanding capacity; however, in practice, this is often not possible. We aim to inform the deliberations of decision makers in high-income settings regarding their cervical cancer screening policy response. We […]
• Utility of a modified distress thermometer in screening COVID-19 patients for psychological distress: a prospective Egyptian study.3rd May 2021
  The National Comprehensive Cancer Network (NCCN) has adopted the distress thermometer (DT) as one of the best-known distress-screening instruments. We have adopted a modified version of the NCCN distress thermometer. We questioned if this modified DT (m-DT) could be utilized for measuring the prevalence of psychological distress among COVID-19 patients.The prospective study included 2 phases; […]
• Clinical laboratory evaluation of COVID-19.3rd May 2021
  COVID-19, caused by SARS-CoV-2, is a highly infectious disease, and clinical laboratory detection has played important roles in its diagnosis and in evaluating progression of the disease. Nucleic acid amplification testing or gene sequencing can serve as pathogenic evidence of COVID-19 diagnosing for clinically suspected cases, and dynamic monitoring of specific antibodies (IgM, IgA, and […]
• Wireless COVID-19 Telehealth: Leukocytes Encryption Guided by Amino Acid Matrix.3rd May 2021
  In this era of wireless COVID-19 telehealth, visiting hospital for regular follow-ups could invite coronavirus in someone’s body. Opting for proactive E-health services is the best thing. It helps the remote patients to share their confidential data through secured encryption. Telehealth services are emerging element in these proactive medical sciences. It helps the remote patients […]
• Fear of COVID-19 as a precautionary measure to prevent the epidemic among the population of the Kurdistan Region/Iraq: based on a questionnaire survey.3rd May 2021
  The World Health Organization (WHO) announced the appearance of a new coronavirus disease in Hubei province, China, to be a public health emergency of international concern. The objectives of this study can be highlighted through classifying the information sources for identifying protective practices, death probability, gender-death associations probability and education level.This is a descriptive design […]
• Does vitamin D serum level affect prognosis of COVID-19 patients?3rd May 2021
  Since beginning of Coronavirus disease of 2019 (COVID-19) pandemic, there were contradictions and speculations around vitamin D and COVID-19 relationship. Given that there is association between vitamin D deficiency and some diseases including cancer, autoimmune disease and some infectious diseases, COVID-19 higher incidence rate and mortality in vitamin D deficient population was not a surprise. […]
• HPV vaccine promotion: Snapshot of two health departments during the COVID-19 pandemic.3rd May 2021
  The COVID-19 pandemic has impacted routine health care services including immunization delivery. The most common sexually transmitted infection in the United States is the human papillomavirus (HPV), and its sequelae may be prevented by vaccination. Sequelae that can develop if one’s immune system is not able to clear the infection include warts, precancerous lesions, and […]
• Lifestyle risk factors and infectious disease mortality, including COVID-19, among middle aged and older adults: Evidence from a community-based cohort study in the United Kingdom.3rd May 2021
  In this community-based cohort study, we investigated the relationship between combinations of modifiable lifestyle risk factors and infectious disease mortality. Participants were 468,569 men and women (56.5 ± 8.1, 54.6% women) residing in the United Kingdom. Lifestyle indexes included traditional and emerging lifestyle risk factors based on health guidelines and best practice recommendations for: physical […]
• Maintaining an Adult Hematology/Oncology Service at a Tertiary Care Center during the SARS-CoV-2 Pandemic: An Eight-Week-Experience with a Newly Implemented Procedural Plan.3rd May 2021
  Treatment of cancer patients has become challenging when large parts of hospital services need to be shut down as a consequence of a local COVID-19 outbreak that requires rapid containment measures, in conjunction with the shifting of priorities to vital services. Reports providing conceptual frameworks and first experiences on how to maintain a clinical hematology/oncology […]
• Mechanisms of Cardiovascular Toxicities Associated with Immunotherapies.3rd May 2021
  Immune-based therapies have revolutionized cancer treatments. Cardiovascular sequelae from these treatments, however, have emerged as critical complications, representing new challenges in cardio-oncology. Immune therapies include a broad range of novel drugs, from antibodies and other biologics, including immune checkpoint inhibitors and bispecific T-cell engagers, to cell-based therapies, such as chimeric-antigen receptor (CAR) T-cell therapies. The […]
• Neuro-oncological patients’ and caregivers’ psychosocial burden during the COVID-19 pandemic – a prospective study with qualitative content analysis.3rd May 2021
  The COVID-19 pandemic may reinforce psychosocial distress of neuro-oncological patients. We aimed to 1) differentiate the burden caused by the pandemic vs. the tumor and 2) establish topics items relevant for brain tumor patients (BTPs) and caregivers.Patients and caregivers were prospectively assessed from April 2020 – July 2020 by a 10-item comprising interview over the […]
• New cancer cases at the time of SARS-Cov2 pandemic and related public health policies: A persistent and concerning decrease long after the end of the national lockdown.3rd May 2021
  The dissemination of SARS-Cov2 may have delayed the diagnosis of new cancers. This study aimed at assessing the number of new cancers during and after the lockdown.We prospectively collected the clinical data of the 11.4 million patients referred to the Assistance Publique Hôpitaux de Paris Teaching Hospital. We identified new cancer cases between 1st January […]
• Quality of life and occupational performance of children with cancer in the era of the COVID-19 pandemic in terms of rehabilitation.3rd May 2021
  This study was designed to determine the changes in the quality of life (QOL) and occupational performance of children with cancer and to examine their rehabilitation needs during the pandemic period in Turkey.60 children with cancer and their families participated in the study. The first and second assessments were carried out in April and September […]
• Risk of Covid-19 infection after resection of high grade transitional cell carcinoma with renal impairment.3rd May 2021
  Covid-19 pandemic has had huge impact on health care system and put the health care system under strain, so efforts made to minimize the elective surgeries however some surgeries especially those for high risk malignant tumors cannot be postponed.The aim of this case report is to highlight the importance of screening cancer patients and those […]
• Severe acute respiratory syndrome coronavirus 2 vaccination for patients with solid cancer: Review and point of view of a French oncology intergroup (GCO, TNCD, UNICANCER).3rd May 2021
  The impacts of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic on cancer care are multiple, entailing a high risk of death from coronavirus disease 2019 (COVID-19) in patients with cancer treated by chemotherapy. SARS-CoV-2 vaccines represent an opportunity to decrease the rate of severe COVID-19 cases in patients with cancer and also to […]
• Being a Myeloproliferative Patient in COVID-19 Era: The Mytico Study.3rd May 2021
  The Coronavirus disease 2019 (COVID-19) pandemic and the resulting social distancing, determined a reduction in access to care and limitations of individual freedom, with a consequent strong impact on quality of life (QoL), anxiety levels and medical management of onco-hematological people. In particular, in the case of patients with chronic myeloproliferative neoplasm (MPN), concern about […]
• The impact of the COVID-19 pandemic on skin cancer incidence and treatment in England, 2020.3rd May 2021
  The first UK national COVID-19 lockdown began 23rd March 2020. Immediately, almost all outpatient healthcare service requests temporarily focused exclusively on urgent referrals and two-week-wait urgent cancer referrals with restrictions due to staff sickness, redeployment and changing work environments. Additionally, patient anxiety regarding attending appointments and perceived overburdening of healthcare resources resulted in fewer presentations.2 […]
• Cardiotoxicity of Immune Checkpoint Inhibitors.3rd May 2021
  Immune checkpoint inhibitors (ICIs) have improved the survival of several cancers. However, they may cause a wide range of immune-related adverse events (irAEs). While most irAEs are manageable with temporary cessation of ICI and immunosuppression, cardiovascular toxicity can be associated with high rates of morbidity and mortality. As ICIs evolve to include high-risk patients with […]
• Predictable fold switching by the SARS-CoV-2 protein ORF9b.2nd May 2021
  Extant fold-switching proteins remodel their secondary structures and change their functions in response to environmental stimuli. These shapeshifting proteins regulate biological processes and are associated with a number of diseases, including tuberculosis, cancer, Alzheimer’s, and autoimmune disorders. Thus, predictive methods are needed to identify more fold-switching proteins, especially since all naturally occurring instances have been […]
• Understanding patients’ views and willingness toward the use of telehealth in a cancer genetics service in Asia.2nd May 2021
  Telehealth is a growing field, its pertinence magnified by COVID-19 causing the accelerated digitalization of the world. Given the significant global demand to provide telehealth services, it is important to explore patient receptiveness toward this alternative service model, particularly from regions where it has yet to be implemented. We conducted a cross-sectional study to understand […]
• Moments in autophagy and disease: Past and present.1st May 2021
  Over the past several decades, research on autophagy, a highly conserved lysosomal degradation pathway, has been advanced by studies in different model organisms, especially in the field of its molecular mechanism and regulation. The malfunction of autophagy is linked to various diseases, among which cancer and neurodegenerative diseases are the major focus. In this review, […]
• Determinants of enhanced vulnerability to coronavirus disease 2019 in UK patients with cancer: a European study.1st May 2021
  Despite high contagiousness and rapid spread, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to heterogeneous outcomes across affected nations. Within Europe (EU), the United Kingdom (UK) is the most severely affected country, with a death toll in excess of 100,000 as of January 2021. We aimed to compare the national impact of coronavirus […]
• NRF2 activation putatively mediates clinical benefits of low-dose radiotherapy in COVID-19 pneumonia and acute respiratory distress syndrome (ards): novel mechanistic considerations.1st May 2021
  Novel mechanistic insights are discussed herein that link a single, nontoxic, low-dose radiotherapy (LDRT) treatment (0.5-1.0 Gy) to (1) beneficial subcellular effects mediated by the activation of nuclear factor erythroid 2-related transcription factor (Nrf2) and to (2) favorable clinical outcomes for COVID-19 pneumonia patients displaying symptoms of acute respiratory distress syndrome (ARDS). We posit that […]
• Temporal trends in inpatient oncology census before and during the COVID-19 pandemic and rates of nosocomial COVID-19 among patients with cancer at a large academic center.1st May 2021
  The Coronavirus Disease-2019 (COVID-19) pandemic has significantly impacted healthcare systems. However, to date, the trend of hospitalizations in the oncology patient population has not been studied and the frequency of nosocomial spread to cancer patients is not well-understood. The objectives of this study were to evaluate the impact of COVID-19 on inpatient oncology census and […]
• Overlap of immunotherapy-related pneumonitis and COVID-19 pneumonia: diagnostic and vaccine considerations.1st May 2021
  The clinically indistinguishable overlap between pneumonitis caused due to immune checkpoint inhibition (ICI) and pneumonia associated with COVID-19 has posed considerable challenges for patients with cancer and oncologists alike. The cancer community continues to face the challenges that lay at the complex immunological intersection of immune-based cancer therapy and immune dysregulation that results from COVID-19. […]