Targeting human milk fortification to improve very preterm infant growth and brain development: study protocol for Nourish, a single-center randomized, controlled clinical trial.

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Human milk is recommended for very preterm infants, but its variable macronutrient content may contribute to undernutrition during a critical period in development. We hypothesize that individually targeted human milk fortification is more effective in meeting macronutrient requirements than the current standard of care.We designed a single-center randomized, controlled trial enrolling 130 infants born

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Authors: Mandy B Belfort, Lianne J Woodward, Sara Cherkerzian, Hunter Pepin, Deirdre Ellard, Tina Steele, Christoph Fusch, P Ellen Grant, Terrie E Inder