Comparative Outcomes of Salvage Retzius-Sparing Versus Standard Robotic Prostatectomy: An International, Multi-Surgeon Series.

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Salvage prostatectomy (SRP) is rare due to the risk of postoperative complications. We compare salvage Retzius-sparing robotic-assisted radical prostatectomy (SRS-RARP) with salvage standard robotic-assisted radical prostatectomy (SS-RARP).72 patients across 9 […]

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Prognostic Impact of Preoperative Plasma Levels of Urokinase Plasminogen Activator Proteins on Disease Outcomes After Radical Cystectomy.

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To validate the association of plasma-levels of urokinase-type plasminogen activator (uPA), its soluble receptor (SuPAR) and its inhibitor (PAI-One) with oncologic outcomes in a large cohort of patients treated with […]

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Top-Down Versus Bottom-Up Approach in Children Presented With Urinary Tract Infection- Comparative Effectiveness Analysis Using RIVUR and CUTIE Data.

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The initial imaging approach to children with urinary tract infection (UTI) is controversial. Along with renal/bladder ultrasound, some advocate VCUG (bottom-up approach) while others advocate DMSA (top-down approach). Comparison of […]

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The Association Between Income Status and Treatment Selection for Prostate Cancer in a Universal Healthcare System: A Population-Based Analysis.

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Treatment selection for localized prostate cancer is guided by risk stratification and patient preferences. While socioeconomic status (SES) disparities exist for access to care, less is known on the effect […]

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The Risk of Prostate Cancer Progression in Active Surveillance Patients With Bilateral Disease Detected by Combined MRI-Fusion and Systematic Biopsy.

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To evaluate whether bilateral prostate cancer detected at Active Surveillance (AS) enrollment is associated with progression to Grade Group ≥2 (GG2) and to compare the efficacy of combined targeted biopsy […]

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Evaluation of Urinary Tract Dilation Classification System for Prediction of Long-Term Outcomes in Isolated Antenatal Hydronephrosis: A Cohort Study.

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The aim of this study was to evaluate the performance of the new classification of urinary tract dilatation (UTD) to predict long-term clinical outcomes in infants with isolated antenatal hydronephrosis […]

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Efficacy of a Novel Penile Traction Device in Improving Penile Length and Erectile Function Post Prostatectomy: Results from a Single-Center Randomized, Controlled Trial.

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RestoreX is a novel penile traction therapy device, with randomized, controlled data demonstrating improvements in penile length and erectile function after 30 to 90 minutes of daily use in men […]

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Efficacy of a Novel Penile Traction Device in Improving Penile Length and Erectile Function Post Prostatectomy: Results from a Single-Center Randomized, Controlled Trial.

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RestoreX is a novel penile traction therapy device, with randomized, controlled data demonstrating improvements in penile length and erectile function after 30 to 90 minutes of daily use in men […]

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Apalutamide Plus Androgen Deprivation Therapy for Metastatic Castration-Sensitive Prostate Cancer: Analysis of Pain and Fatigue in the Phase 3 TITAN Study.

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Exploratory analysis of prostate cancer-related pain and fatigue on health-related quality of life in patients with metastatic castration-sensitive prostate cancer (mCSPC) receiving apalutamide (240 mg/day) or placebo, with continuous androgen-deprivation […]

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A Predictive Pre- and Post-operative Nomogram for Post-operative Potency Recovery after Robot-Assisted Radical Prostatectomy.

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Prediction of potency recovery following RARP is useful for better patient counselling and post-operative treatment strategies. In this study we propose a pre-operative and post-operative nomogram to predict post-operative potency […]

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Cardiovascular Proteomics: A Post-hoc Analysis from a Phase II Randomized Clinical Trial Comparing GnRH Antagonist Vs GnRH Agonist Among Men with Advanced Prostate Cancer.

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Recent studies demonstrated reduced cardiovascular risk with GnRH antagonist, yet the underlying mechanism remains undetermined. The objective of this study was to examine longitudinal changes over time in established cardiovascular […]

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Disparate Practice Patterns and Survival Outcomes: The Impact of Centralization of Cancer Care for Adrenocortical Carcinoma in the United States.

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Adrenocortical carcinoma is a rare but aggressive malignancy. While centralization of care to referral centers improves outcomes across common urologic malignancies, there exists a paucity of data for low-incidence cancers. […]

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Interstitial Cystitis/Bladder Pain Syndrome’s Correlations with Pregnancy and Neonatal Outcomes: A Study of a Population Database.

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To evaluate the associations with interstitial cystitis during pregnancy using a United States inpatient database.We conducted a retrospective cohort study utilizing the Nationwide Inpatient Sample database from the Healthcare Cost […]

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One-Stage Buccal Mucosal Graft Urethroplasty for Lichen Sclerosus Related Urethral Stricture Disease: A Systematic Review and Pooled Proportional Meta-Analysis.

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Performing one-stage urethroplasty in patients with urethral strictures caused by lichen sclerosis (LS) is hotly debated among reconstructive urologists due to conflicting reports of success. Therefore, the objective of this […]

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Pathologic Downstaging and Survival Outcomes Associated with Neoadjuvant Chemotherapy for Variant Histology Muscle Invasive Bladder Cancer.

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Patients with muscle invasive bladder cancer (MIBC) of variant histology have a poor prognosis. It is unclear if neoadjuvant chemotherapy prior to radical cystectomy is associated with pathologic downstaging or […]

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Real World Practice Patterns and Predictors of Continuous versus Intermittent ADT Use for Prostate Cancer in Older Men.

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Phase-III RCT evidence suggests intermittent ADT (IADT) is not significantly inferior to continuous ADT for prostate cancer (PC) patients. However, clinical practice and guidelines differ in their recommendations. We evaluate […]

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Timing of Androgen Deprivation Treatment for Men with Biochemical Recurrent Prostate Cancer in the Context of Novel Therapies.

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There were three recent FDA approvals for drugs to be used in non-metastatic castration resistant prostate cancer, a state that arises from the unproven start of continuous androgen deprivation therapy […]

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