High-frequency Cochlear Nerve Deficit Region: Relationship With Deaf Duration and Cochlear Implantation Performance in Postlingual Deaf Adults.

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To analyze the changes of cochlear nerve diameter and the presence of a cochlear nerve deficit at a high-frequency region and investigate their effects on cochlear implant (CI) performance in […]

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Imaging Characteristics of Sigmoid Sinus Wall Anomalies, Idiopathic Intracranial Hypertension, and Spontaneous CSF Leaks.

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To assess the frequency of radiographic features of elevated intracranial pressure (ICP) in patients with sigmoid sinus wall anomalies (SSWA) and compare to those in idiopathic intracranial hypertension (IIH) and […]

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Improved Speech Intelligibility in Subjects With Stable Sensorineural Hearing Loss Following Intratympanic Dosing of FX-322 in a Phase 1b Study.

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There are no approved pharmacologic therapies for chronic sensorineural hearing loss (SNHL). The combination of CHIR99021+valproic acid (CV, FX-322) has been shown to regenerate mammalian cochlear hair cells ex vivo. […]

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Sudden Brief Unilateral Tapering Tinnitus (SBUTT) Is Closely Related to the Lateral Pterygoid Muscle.

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To determine the cause of sudden brief unilateral tapering tinnitus (SBUTTs).Five adults evaluated at a tertiary tinnitus referral center.Dry needling of lateral pterygoid muscle of one patient; jaw maneuvers in […]

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Dilatation of the Endolymphatic Space in the Ampulla of the Posterior Semicircular Canal: A New Clinical Finding Detected on Magnetic Resonance Imaging.

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To investigate the clinical features of ears with dilatation of the endolymphatic space in the ampulla of the posterior semicircular canal on magnetic resonance imaging.Retrospective study.A university hospital.This study included […]

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Further Evidence for the Expansion of Adult Cochlear Implant Candidacy Criteria.

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1) To complete a follow-up investigation of postoperative outcomes for adult cochlear implant (CI) recipients scoring ≥30% Consonant-Nucleus-Consonant (CNC) preoperatively, and 2) to describe the postoperative performance trajectory for this […]

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Imbalance Associated With Cisplatin Chemotherapy in Adult Cancer Survivors: A Clinical Study.

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This study investigated balance problems and vestibular function in adult cancer survivors who had completed cisplatin chemotherapy treatment.Observational cross-sectional study.Tertiary care center.Adult survivors of cancer who had completed cisplatin treatment.Patient-reported […]

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Intraoperative Auditory Brainstem Response Results Predict Delayed Sensorineural Hearing Loss After Middle Cranial Fossa Resection of Vestibular Schwannoma.

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To identify intraoperative neurophysiologic measures predictive of delayed progressive sensorineural hearing loss in the operative ear after a middle fossa approach (MCF) for resection of vestibular schwannoma (VS).Retrospective review.Academic, tertiary […]

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Preoperative Sudden Hearing Loss May Predict Hearing Preservation After Retrosigmoid Resection of Vestibular Schwannoma.

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Describe the effect of preoperative sudden hearing loss (SHL) on likelihood of hearing preservation (HP) after surgical resection of vestibular schwannoma (VS).Retrospective chart review.Tertiary referral center.Adult patients (≥18 years) who underwent […]

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Study on the Bone Metabolism Indices and Otoconin-90 in Benign Paroxysmal Positional Vertigo.

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To investigate the correlation between benign paroxysmal positional vertigo (BPPV) and abnormal bone metabolism and to evaluate the value of otoconial protein otoconin-90 in the pathogenesis research and clinical treatment […]

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Subjective Cognitive Symptoms and Dizziness Handicap Inventory (DHI) Performance in Patients With Vestibular Migraine and Menière’s Disease.

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Cognitive symptoms in patients with vestibular disorders are far from rare, but identification of patients at risk for cognitive impairment remains poor. The Dizziness Handicap Inventory (DHI) is a widely […]

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Towards Providing an Automated Approach to Differentiating the Nystagmus of Ménière’s Disease, Vestibular Migraine, and Benign Paroxysmal Positional Vertigo.

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The diagnosis of vertigo is challenging, particularly as patients usually present while asymptomatic. We have developed an ambulatory medical device that allows vestibular telemetry to record eye movements over a […]

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Usage Patterns of CT and MRI in the Evaluation of Otologic Disease.

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To evaluate the current trends and usage patterns of radiographic imaging for otologic disease by specialty, length of practice, practice setting, geographic region, and pediatric volume.Cross-sectional study.Survey of physicians.General Otolaryngologists […]

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Are Opioids Necessary in Middle Ear Surgery? Comparing the Transcanal and Postauricular Approach.

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Understand opioid-prescribing patterns in otologic surgery and the difference in opioid use between transcanal and postauricular surgery.Prospective survey.Multihospital network.All patients undergoing otologic surgery from March 2017 to January 2019.Patients undergoing […]

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Risk of Sensorineural Hearing Loss in Patulous Eustachian Tube.

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To investigate whether the long-term presence of a patulous Eustachian tube (PET) is associated with sensorineural hearing loss (SNHL).Retrospective chart review.Tertiary referral center.Ears (n = 100) were classified into two groups based […]

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Bilateral Cochlear Implantation in Children: Long-Term Outcome in the Adult Population With Special Emphasis on the Bilateral Benefit.

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To investigate the benefit of bilateral cochlear implantation in adults, who had been implanted being a child under the age of 10 years.Retrospective data analysis.Tertiary referral center with a large […]

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Pre-existing Vestibular Symptoms Are Associated With Acute Vestibular Symptoms After Gamma Knife Therapy for Vestibular Schwannoma.

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To identify pretreatment variables associated with the development of acute vestibular symptoms after Gamma Knife (GK) treatment for Vestibular Schwannoma (VS).Retrospective case series.Tertiary neurotology referral center.Patients treated with GK radiosurgery […]

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Bilateral Vestibulopathy in Neuroborreliosis.

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To describe a unique case of definite neuroborreliosis presenting with bilateral vestibulopathy (BV) due to simultaneous involvement of both vestibular systems highlighted by a complete assessment for all five vestibular […]

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The Viability and Growth of HaCaT Cells After Exposure to Bioactive Glass S53P4-Containing Cell Culture Media.

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Bioactive glass (BG) S53P4 reduces the viability of epidermal keratinocyte-derived immortalized cell line, HaCaT in sufficient concentrations in vitro.Although used in mastoid obliteration surgery, there is no data available on […]

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Three-Dimensional (3D) Printed Vestibular Schwannoma for Facial Nerve Tractography Validation.

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Predicting the course of cranial nerve (CN) VII in the cerebellopontine angle (CPA) on preoperative imaging for vestibular schwannoma (VS) may help guide surgical resection and reduce complications. Diffusion MRI […]

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Vestibular Schwannoma Measurements-Is Volumetric Analysis Clinically Necessary?

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1) To compare vestibular schwannoma maximum linear dimensions and calculated volume with measured volume in accurately determining tumor volume and growth. 2) To determine natural growth history of vestibular schwannomas […]

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Hearing Outcomes With a Novel Total Ossicular Replacement Prosthesis.

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A total ossicular replacement prosthesis (TORP) is used to reconstruct the ossicular chain in the absence of the stapes suprastructure. The Wildcat prosthesis is a novel TORP that eliminates the […]

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Intracanalicular Vestibular Schwannoma: A Systematic Review and Meta-analysis of Therapeutics Outcomes.

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To perform a systematic review and meta-analysis summarizing the current evidence on the management of intracanalicular vestibular schwannoma.Embase (1947-), Medline (1946-), Cochrane library (1947-), Scopus (2010-), and CINAHL (1961-) were […]

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Management of Intractable Petrous Bone Cholesteatoma With a Combined Translabyrinthine-Transsphenoidal Approach.

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To evaluate whether a combined translabyrinthine-transsphenoidal approach can be used to achieve adequate surgical resection of an extensive petrous bone cholesteatoma and create a debris drainage route for the residual […]

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New Compartmental Reading Method for MRI Enables Accurate Localization of Cholesteatomas With High Sensitivity and Specificity.

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Cholesteatoma is an inflammatory disease, frequently observed in childrens and young adults, with a risk of relapse or recurrence. The few studies which analyzed cholesteatoma localization on magnetic resonance imaging […]

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Precise Evaluation of the Cochlear Duct Length by Flat-panel Volume Computed Tomography (fpVCT)-Implication of Secondary Reconstructions.

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Flat-panel volume computed tomography (fpVCT) and secondary reconstruction allow for more accurate measurements of two-turn length (2TL), cochlear duct length (CDL), and angular length (AL).Cochlear geometry is a controversially debated […]

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Projected Cost Simulation in Chronic Ear Surgery: Cost in Chronic Ear Surgery.

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To examine the projected healthcare costs of intact canal wall (ICW) and canal wall down (CWD) tympanomastoidectomy surgery and associated clinic follow-up visits in the management of chronic ear disease.A […]

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Streamlining the Cochlear Implant Evaluation: Utility of Community Audiometry in Cochlear Implant Candidacy Assessment.

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To identify redundancy in the cochlear implant candidacy evaluation and assess its financial impact.Retrospective chart review.Tertiary care academic cochlear implant center.One hundred thirty-five patients referred for cochlear implant candidacy evaluation […]

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Subjective Visual Vertical Evaluation by a Smartphone-based Test-Taking the Phone Out of the Bucket.

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To measure the subjective visual vertical (SVV) in patients suffering from peripheral vestibular disorders versus controls, using a smartphone-based test designed to simulate the bucket test, in order to validate […]

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Attitudes of Potential Participants Towards Potential Gene Therapy Trials in Autosomal Dominant Progressive Sensorineural Hearing Loss.

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Advances in gene therapeutic approaches to treat sensorineural hearing loss (SNHL) confront us with future challenges of translating these animal studies into clinical trials. Little is known on patient attitudes […]

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