Petrous Apex Cephaloceles: Radiology Features and Surgical Management of a Rare Entity.

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To characterize the radiologic findings of petrous apex cephalocele (PAC) in a patient cohort, and report the surgical management for three symptomatic PAC patients and cerebrospinal fluid (CSF) leak via […]

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Predictors of Postoperative Electrode Deactivation Among Adult Cochlear Implantees.

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To characterize postoperative electrode functionality after adult cochlear implantation; to identify rationale and risk factors for electrode deactivation.Retrospective Chart Review.Academic Cochlear Implant Center.Five hundred nineteen cochlear implants in 433 adult […]

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Prevalence of Otological Disease in Turner Syndrome: A Systematic Review.

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Girls and women with Turner syndrome (TS) present with multiple ear and hearing problems, ranging from external morphologic abnormalities to sensorineural or conductive hearing loss. The exact pathophysiology behind these […]

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Rising Resonance Frequency Is the Sole Sign of Early Middle Ear Disease in Children With Adenoid Hypertrophy.

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The present study seeks to estimate the potential of multifrequency tympanometry in the diagnosis of primal otologic disorder in children with adenoid hypertrophy (AH).Prospective observational study.Tertiary pediatric institution.One hundred thirty-one […]

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Audiometric Pattern in Moderate and Severe Tympanic Membrane Retraction.

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To evaluate the audiometric pattern in moderate/severe retractions of the tympanic membrane and correlate it with the severity of the otoscopy findings.Cross-sectional study.Tertiary hospital.Consecutive patients with moderate or severe tympanic […]

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Can a Self-report Measure Be Used to Assess Cognitive Skills in Adults With Hearing Loss?

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Adult cochlear implant candidates would self-report their executive functioning abilities as poorer than normal-hearing peers. These executive function abilities would correlate with laboratory-based cognitive tests. Lastly, executive functioning (EF) abilities […]

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Charcot-Marie-Tooth Disease With Long-Term Follow-Up on Auditory Neuropathy-After Cochlear Implantation Or Hearing Aid Use.

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To study the pathophysiology of Charcot-Marie-Tooth disease (CMT) with auditory neuropathy (AN) and to follow up cochlear implant or hearing aid use over the long term.Clinical capsule report.Two adult CMT […]

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Comparison of Speech Recognition With an Organ of Corti Versus Spiral Ganglion Frequency-to-Place Function in Place-Based Mapping of Cochlear Implant and Electric-Acoustic Stimulation Devices.

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To compare acute speech recognition with a cochlear implant (CI) alone or electric-acoustic stimulation (EAS) device for place-based maps calculated with an organ of Corti (OC) versus a spiral ganglion […]

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Cost-utility Analysis of Cochlear Implantation in Adults With Single-sided Deafness: Austrian and German Perspective.

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Single-sided deafness (SSD) is associated with a loss of binaural hearing. Major limitations of such patients are poor speech understanding in noisy environments and a lack of spatial hearing. To […]

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High-frequency Cochlear Nerve Deficit Region: Relationship With Deaf Duration and Cochlear Implantation Performance in Postlingual Deaf Adults.

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To analyze the changes of cochlear nerve diameter and the presence of a cochlear nerve deficit at a high-frequency region and investigate their effects on cochlear implant (CI) performance in […]

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Imaging Characteristics of Sigmoid Sinus Wall Anomalies, Idiopathic Intracranial Hypertension, and Spontaneous CSF Leaks.

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To assess the frequency of radiographic features of elevated intracranial pressure (ICP) in patients with sigmoid sinus wall anomalies (SSWA) and compare to those in idiopathic intracranial hypertension (IIH) and […]

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Improved Speech Intelligibility in Subjects With Stable Sensorineural Hearing Loss Following Intratympanic Dosing of FX-322 in a Phase 1b Study.

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There are no approved pharmacologic therapies for chronic sensorineural hearing loss (SNHL). The combination of CHIR99021+valproic acid (CV, FX-322) has been shown to regenerate mammalian cochlear hair cells ex vivo. […]

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Sudden Brief Unilateral Tapering Tinnitus (SBUTT) Is Closely Related to the Lateral Pterygoid Muscle.

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To determine the cause of sudden brief unilateral tapering tinnitus (SBUTTs).Five adults evaluated at a tertiary tinnitus referral center.Dry needling of lateral pterygoid muscle of one patient; jaw maneuvers in […]

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Imbalance Associated With Cisplatin Chemotherapy in Adult Cancer Survivors: A Clinical Study.

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This study investigated balance problems and vestibular function in adult cancer survivors who had completed cisplatin chemotherapy treatment.Observational cross-sectional study.Tertiary care center.Adult survivors of cancer who had completed cisplatin treatment.Patient-reported […]

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Intraoperative Auditory Brainstem Response Results Predict Delayed Sensorineural Hearing Loss After Middle Cranial Fossa Resection of Vestibular Schwannoma.

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To identify intraoperative neurophysiologic measures predictive of delayed progressive sensorineural hearing loss in the operative ear after a middle fossa approach (MCF) for resection of vestibular schwannoma (VS).Retrospective review.Academic, tertiary […]

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Preoperative Sudden Hearing Loss May Predict Hearing Preservation After Retrosigmoid Resection of Vestibular Schwannoma.

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Describe the effect of preoperative sudden hearing loss (SHL) on likelihood of hearing preservation (HP) after surgical resection of vestibular schwannoma (VS).Retrospective chart review.Tertiary referral center.Adult patients (≥18 years) who underwent […]

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Study on the Bone Metabolism Indices and Otoconin-90 in Benign Paroxysmal Positional Vertigo.

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To investigate the correlation between benign paroxysmal positional vertigo (BPPV) and abnormal bone metabolism and to evaluate the value of otoconial protein otoconin-90 in the pathogenesis research and clinical treatment […]

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Subjective Cognitive Symptoms and Dizziness Handicap Inventory (DHI) Performance in Patients With Vestibular Migraine and Menière’s Disease.

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Cognitive symptoms in patients with vestibular disorders are far from rare, but identification of patients at risk for cognitive impairment remains poor. The Dizziness Handicap Inventory (DHI) is a widely […]

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Towards Providing an Automated Approach to Differentiating the Nystagmus of Ménière’s Disease, Vestibular Migraine, and Benign Paroxysmal Positional Vertigo.

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The diagnosis of vertigo is challenging, particularly as patients usually present while asymptomatic. We have developed an ambulatory medical device that allows vestibular telemetry to record eye movements over a […]

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Usage Patterns of CT and MRI in the Evaluation of Otologic Disease.

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To evaluate the current trends and usage patterns of radiographic imaging for otologic disease by specialty, length of practice, practice setting, geographic region, and pediatric volume.Cross-sectional study.Survey of physicians.General Otolaryngologists […]

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Are Opioids Necessary in Middle Ear Surgery? Comparing the Transcanal and Postauricular Approach.

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Understand opioid-prescribing patterns in otologic surgery and the difference in opioid use between transcanal and postauricular surgery.Prospective survey.Multihospital network.All patients undergoing otologic surgery from March 2017 to January 2019.Patients undergoing […]

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Dilatation of the Endolymphatic Space in the Ampulla of the Posterior Semicircular Canal: A New Clinical Finding Detected on Magnetic Resonance Imaging.

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To investigate the clinical features of ears with dilatation of the endolymphatic space in the ampulla of the posterior semicircular canal on magnetic resonance imaging.Retrospective study.A university hospital.This study included […]

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Further Evidence for the Expansion of Adult Cochlear Implant Candidacy Criteria.

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1) To complete a follow-up investigation of postoperative outcomes for adult cochlear implant (CI) recipients scoring ≥30% Consonant-Nucleus-Consonant (CNC) preoperatively, and 2) to describe the postoperative performance trajectory for this […]

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Risk of Sensorineural Hearing Loss in Patulous Eustachian Tube.

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To investigate whether the long-term presence of a patulous Eustachian tube (PET) is associated with sensorineural hearing loss (SNHL).Retrospective chart review.Tertiary referral center.Ears (n = 100) were classified into two groups based […]

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Bilateral Cochlear Implantation in Children: Long-Term Outcome in the Adult Population With Special Emphasis on the Bilateral Benefit.

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To investigate the benefit of bilateral cochlear implantation in adults, who had been implanted being a child under the age of 10 years.Retrospective data analysis.Tertiary referral center with a large […]

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Pre-existing Vestibular Symptoms Are Associated With Acute Vestibular Symptoms After Gamma Knife Therapy for Vestibular Schwannoma.

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To identify pretreatment variables associated with the development of acute vestibular symptoms after Gamma Knife (GK) treatment for Vestibular Schwannoma (VS).Retrospective case series.Tertiary neurotology referral center.Patients treated with GK radiosurgery […]

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Bilateral Vestibulopathy in Neuroborreliosis.

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To describe a unique case of definite neuroborreliosis presenting with bilateral vestibulopathy (BV) due to simultaneous involvement of both vestibular systems highlighted by a complete assessment for all five vestibular […]

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The Viability and Growth of HaCaT Cells After Exposure to Bioactive Glass S53P4-Containing Cell Culture Media.

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Bioactive glass (BG) S53P4 reduces the viability of epidermal keratinocyte-derived immortalized cell line, HaCaT in sufficient concentrations in vitro.Although used in mastoid obliteration surgery, there is no data available on […]

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Three-Dimensional (3D) Printed Vestibular Schwannoma for Facial Nerve Tractography Validation.

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Predicting the course of cranial nerve (CN) VII in the cerebellopontine angle (CPA) on preoperative imaging for vestibular schwannoma (VS) may help guide surgical resection and reduce complications. Diffusion MRI […]

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Vestibular Schwannoma Measurements-Is Volumetric Analysis Clinically Necessary?

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1) To compare vestibular schwannoma maximum linear dimensions and calculated volume with measured volume in accurately determining tumor volume and growth. 2) To determine natural growth history of vestibular schwannomas […]

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