Tumor invasion in the hyponychium is associated with distant metastasis and poor prognosis in subungual melanoma: A histological landscape of 44 cases.

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Subungual melanoma (SUM) has a poor prognosis due to delayed diagnosis. The progression, consensus on surgical treatment, correlation with clinical outcomes remains unclear.We aimed to identify the pattern of dermal […]

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Late-onset adverse events under anti-PD1 therapy in melanoma patients: an observational study from MELBASE, a nationwide prospective cohort.

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The purpose was to evaluate late-onset AEs in melanoma patients treated with anti-PD1 administered at least 2 years in a real-life setting. Patients were screened from MelBase (NCT02828202), a French […]

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Prevalence of Depression among Children, Adolescents, and Adults with Hidradenitis Suppurativa.

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Information on prevalence of depression among children, adolescents and adults with hidradenitis suppurativa (HS) is limited.To compare prevalence of depression in HS patients with that of controls.Cross-sectional analysis of 38,140 […]

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Delgocitinib ointment in pediatric patients with atopic dermatitis: a phase 3, randomized, double-blind, vehicle-controlled study and a subsequent open-label, long-term study.

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Delgocitinib 0.5% ointment, a topical JAK inhibitor, has been approved for adult patients with atopic dermatitis (AD) in Japan.To evaluate the efficacy and safety of delgocitinib ointment in pediatric patients […]

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Diagnosing muscle disease in a cohort of classic dermatomyositis patients seen at a rheumatologic dermatology outpatient clinic.

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Existing criteria include muscle biopsies to improve the probability of capturing dermatomyositis (DM), but not much is known whether less invasive diagnostic procedures may be just as useful.We aim to […]

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Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement.

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Frontal fibrosing alopecia/FFA is a progressive, scarring alopecia of the frontotemporal scalp, and poses a substantial burden on quality of life. Largescale global profiling of FFA is lacking, preventing the […]

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Systematic Review and Meta-Analysis of Local Recurrence Rates of Head and Neck Cutaneous Melanomas after Wide Local Excision, Mohs Micrographic Surgery, or Staged Excision.

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Prospective trials have not compared local recurrence rates for different excision techniques for cutaneous melanomas on the head and neck.To determine local recurrence rates of cutaneous head and neck melanoma […]

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Efficacy and Safety of Ruxolitinib Cream for the Treatment of Atopic Dermatitis: Results From Two Phase 3, Randomized, Double-Blind Studies.

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Ruxolitinib (RUX) cream demonstrated potent anti-inflammatory and antipruritic efficacy in a phase 2 study in adults with atopic dermatitis (AD).To evaluate 8-week efficacy and safety in two phase 3 studies […]

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Dermatologic Support for Oncology: Quantifying the consultative services received by hospitalized oncology patients.

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Dermatology was the fifth most utilized consultative service by Oncology when compared to the 101 other inpatient consultative services. Patients receiving dermatology consults had longer lengths of stay. Previous work […]

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Article Topic/Title: Primary cutaneous T-cell lymphomas other than Mycosis Fungoides and Sezary Syndrome. Part II: Prognosis and Management.

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Primary cutaneous T-cell lymphomas (CTCLs) other than Mycosis Fungoides (MF) and Sézary syndrome (SS) encompass a heterogenous group of non-Hodgkin lymphomas with variable clinical course, prognoses, and management. With morphologic […]

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Performance of ABCD-10 and SCORTEN Mortality Prediction Models in a Cohort of Patients with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.

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ABCD-10 has recently been proposed as an alternative to the SCORTEN model for predicting in-hospital mortality in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. In contrast to SCORTEN, ABCD-10 […]

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Primary cutaneous T-cell lymphomas other than Mycosis Fungoides and Sezary Syndrome – Part I: Clinical and histologic features and diagnosis.

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Primary cutaneous T-cell lymphomas (CTCLs) are defined as lymphomas with a T-cell phenotype that present in the skin without evidence of systemic or extracutaneous disease at initial presentation. CTCLs other […]

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Mycoplasma induced Steven-Johnson Syndrome/Toxic Epidermal Necrolysis: Case-control analysis of a cohort managed in a specialized center.

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Mycoplasma pneumoniae (MP) infection is associated with extrapulmonary complications such as Stevens-Johnson syndrome (SJS)/Toxic epidermal necrolysis(TEN).We evaluated the differences in epidemiology, clinical characteristics, and disease outcomes between drug-induced and mycoplasma […]

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Clinical Impact of Immunotherapy in Merkel Cell Carcinoma patients: A Systematic Review and Meta-Analysis.

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Immunotherapy is emerging as an alternative for Merkel cell carcinoma (MCC), but its long-term effects on response, survival, and safety are not well established. High-quality evidence is needed to estimate […]

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Hand eczema and temporal variation of Staphylococcus aureus clonal complexes: A prospective observational study.

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Hand eczema (HE) is frequently colonized with Staphylococcus aureus (S. aureus); however, its role in the pathogenesis of HE is poorly understood.To investigate temporal variation of S. aureus sub-types, i.e. […]

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Stimulant use in patients presenting with psychocutaneous disorders.

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Psychocutaneous disorders are often attributed to stimulant medications, yet this relationship has never been fully elucidated. Literature on psychocutaneous disorders largely focuses on clinical presentation and treatment rather than disease […]

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