Mechanisms and primary prevention of atherosclerotic cardiovascular disease among people living with HIV.

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To highlight mechanisms of elevated risk of atherosclerotic cardiovascular disease (ASCVD) among people living with HIV (PLWH), discuss therapeutic strategies, and opportunities for primary prevention.HIV-associated ASCVD risk is likely multifactorial […]

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Clinical consequences of asymptomatic cytomegalovirus in treated human immunodeficency virus infection.

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Despite antiretroviral therapy (ART)-mediated viral suppression, people with human immunodeficiency virus (HIV) (PWH) have increased morbidity and mortality. Immune activation and inflammation persist on ART and predict these complications. Over […]

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Recent data on adipose tissue, insulin resistance, diabetes and dyslipidaemia in antiretroviral therapy controlled HIV-infected persons.

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Increased total body fat with truncal redistribution is common in antiretroviral therapy (ART)-controlled persons living with HIV(PLWH), leading to insulin resistance, prediabetes/diabetes and dyslipidaemia. We address these topics here.Most antiretrovirals […]

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Potential and demonstrated impacts of the COVID-19 pandemic on sexually transmissible infections: Republication.

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This review considers the potential and demonstrated impacts of SARS-CoV-2 on the sexually transmissible infection (STI)/HIV transmission.COVID-19 increases the vulnerability of those at highest risk of acquiring STI/HIV. Altered health-seeking […]

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COVID-19 antibody development fueled by HIV-1 broadly neutralizing antibody research.

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The coronavirus disease 2019 (COVID-19) pandemic has caught the world unprepared, with no prevention or treatment strategies in place. In addition to the efforts to develop an effective vaccine, alternative […]

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COVID-19 antibody development fueled by HIV-1 broadly neutralizing antibody research.

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The coronavirus disease 2019 (COVID-19) pandemic has caught the world unprepared, with no prevention or treatment strategies in place. In addition to the efforts to develop an effective vaccine, alternative […]

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Molecular epidemiology in the HIV and SARS-CoV-2 pandemics.

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The aim of this review was to compare and contrast the application of molecular epidemiology approaches for the improved management and understanding of the HIV versus SARS-CoV-2 epidemics.Molecular biology approaches, […]

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Adaptation of advanced clinical virology assays from HIV-1 to SARS-CoV-2.

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In response to the HIV-AIDS pandemic, great strides have been made in developing molecular methods that accurately quantify nucleic acid products of HIV-1 at different stages of viral replication and […]

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The interplay between HIV and COVID-19: summary of the data and responses to date.

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We examine the interplay between the HIV and COVID-19 epidemics, including the impact of HIV on COVID-19 susceptibility and severe disease, the effect of the COVID-19 epidemic on HIV prevention […]

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The single-cell landscape of immunological responses of CD4+ T cells in HIV versus severe acute respiratory syndrome coronavirus 2.

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CD4 T cell loss is the hallmark of uncontrolled HIV-1 infection. Strikingly, CD4 T cell depletion is a strong indicator for disease severity in the recently emerged coronavirus disease 2019 […]

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The first 6 months of HIV-SARS-CoV-2 coinfection: outcomes for 6947 individuals.

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The aim of this review is to summarize the clinical outcomes of people living with HIV (PWH) coinfected with SARS-CoV-2 during the first six months of the COVID-19 pandemic.Several reports […]

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Treatment of coronavirus disease 2019.

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Coronavirus disease 2019 (COVID-19) is a highly contagious and potentially lethal pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). No specific antiviral treatment is currently available. The […]

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Coronavirus disease-19 vaccine development utilizing promising technology.

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Coronavirus disease-19 (COVID-19) is a highly transmittable and pathogenic pneumonia-causing disease, which is caused by severe acute respiratory syndrome coronavirus-2, resulting in millions of deaths globally. Severe acute respiratory syndrome […]

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