Gastroparesis and functional dyspepsia: different diseases or different ends of the spectrum?

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This review assesses the relationship between gastroparesis and functional dyspepsia, in light of recent research assessing cause, pathophysiology and treatment.The Gastroparesis Cardinal Symptom Index (GCSI) lacks the ability to readily […]

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Host immune interactions in chronic inflammatory gastrointestinal conditions.

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We performed a literature review of the latest studies on the interactions between the host immune system and microbes in chronic intestinal inflammatory conditions.The mechanisms leading to celiac disease (CeD) […]

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Role of endoscopic ultrasonography guided fiducial marker placement in gastrointestinal cancer.

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Dose escalation radiation therapy such as those delivered by stereotactic body radiation therapy (SBRT) has shown to improve local disease control in multiple types of malignancies. This requires fiducial placement […]

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Endoscope infection transmission state-of-the-art: beyond duodenoscopes to a culture of infection prevention.

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The elevator mechanism of the duodenoscope was the focus of endoscopically transmitted infections prior to the COVID-19 pandemic. Since that time, the ‘suspicious suspects’ in the endoscopy unit have grown […]

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The importance of anal cancer screening and high-resolution anoscopy to gastroenterology practice.

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Although human papillomavirus (HPV)-related anal squamous cell cancer (ASCC) is rare, its incidence has been rising and in high-risk populations exceeds the incidence of cancers for which screening programs are […]

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Intravenous fluid resuscitation in the management of acute pancreatitis.

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In the absence of proven effective pharmacologic therapy in acute pancreatitis, and given its simplicity, wide availability, and perceived safety, intravenous fluid resuscitation remains the cornerstone in the early treatment […]

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Endoscopic eradication therapy for Barrett’s oesophagus: state of the art.

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Barrett’s oesophagus is the only identifiable precursor lesion to oesophageal adenocarcinoma. The stepwise progression of Barrett’s oesophagus to dysplasia and invasive carcinoma provides the opportunity to intervene and reduce the […]

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The management of the hospitalized ulcerative colitis patient: the medical-surgical conundrum.

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In this review article, we address emerging evidence for the medical and surgical treatment of the hospitalized patient with ulcerative colitis.Ulcerative colitis is a chronic inflammatory disease involving the colon […]

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How to advise patients on the risk of chronic proton pump inhibitor therapy.

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Proton pump inhibitors (PPIs) are widely prescribed and have excellent short-term tolerability. Administrative database studies have highlighted that many diseases are associated with PPI therapy including pneumonia, fracture, cardiovascular disease, […]

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