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Identification of pathological changes in early and mild obstructive lung disease has revealed the importance of the small airways and their contribution to symptoms. Indeed, significant small airways dysfunction has […]
» Read moreLong-term cognitive impairment frequently occurs after critical illness; no treatments are known to improve long-term cognition.Does a single high-dose (540,000 IU) enteral treatment of vitamin D3 given shortly after hospital […]
» Read moreBiomarkers in chronic obstructive pulmonary disease may be clinical (prior exacerbation history), physiological (forced expiratory volume in one second), or blood based (eosinophil count or fibrinogen level). There has been […]
» Read moreSurvivors of COVID-19 are a vulnerable population, with complex needs owing to lingering symptoms and complications across multiple organ systems. Those who required hospitalization or intensive care are also at […]
» Read moreHormone replacement therapy is prescribed to millions of women worldwide. Previous studies have suggested that hormone replacement therapy has both protective and harmful effects in asthma.Is hormone replacement therapy in […]
» Read moreDelirium is a deleterious condition affecting up to 60% of patients in the surgical intensive care unit (SICU). Few SICU-focused delirium interventions have been implemented, including those addressing sleep-wake disruption, […]
» Read moreFamily members of ICU patients experience a constellation of sequelae described as post-intensive care syndrome-family. The influence that an inter-ICU transfer has on psychological outcomes is unknown.Is inter-ICU transfer associated […]
» Read moreVisceral pleural invasion (VPI) with PL1 or PL2 increases the T classification from T1 to T2 in non-small cell lung cancers (NSCLCs) 3 cm or less. We proposed a modified […]
» Read moreLung cancer screening (LCS) is effective at reducing mortality for high-risk smokers. Mortality benefits go beyond early cancer detection, as shared-decision making (SDM) may present a “teachable moment” to reinforce […]
» Read moreSex and gender differences in lung health and disease are imperative to consider and study if precision pulmonary medicine is to be achieved. The development of reliable COPD biomarkers has […]
» Read moreIndwelling tunneled pleural catheters are commonly used for recurrent pleural effusion management. Catheter obstruction is not uncommon, often requiring intrapleural medications instillation (i.e., alteplase) to restore flow. The safety profile […]
» Read moreJoblessness is common after ARDS, but related risk factors are not fully understood.What is the association between survivors’ pre-ARDS workload and post-ARDS functional impairment, pain, and fatigue with their return […]
» Read moreChildren have been less impacted by the Coronavirus disease 19 (COVID) pandemic, but its repercussions on pediatric illnesses may have been significant. We examined the indirect impact of the pandemic […]
» Read moreVentilator-associated pneumonia (VAP) is the most frequent healthcare-associated infection in severely ill patients and aspiration of contaminated oropharyngeal content around the cuff of the tracheal tube is the main route […]
» Read moreStudies have reported an increased risk for asthma following lower respiratory tract infections, but few studies have specifically assessed this risk in children diagnosed with pneumonia in infancy. Further, it […]
» Read moreThe coronavirus disease 2019 (COVID-19) pandemic placed considerable strain on critical care resources. How United States (U.S.) hospitals responded to this crisis is unknown.What actions did U.S. hospitals take to […]
» Read moreThe coronavirus disease 2019 (COVID-19) pandemic placed considerable strain on critical care resources. How United States (U.S.) hospitals responded to this crisis is unknown.What actions did U.S. hospitals take to […]
» Read moreThe COVID-19 pandemic has led to unprecedented demand for ICU, with the need to triage admissions along with the development of ICU triage criteria. However, how these criteria relate to […]
» Read moreDifferent lung ultrasound (LUS) scanning protocols have been used and the results in terms of diagnostic accuracy are heterogeneous.What is the diagnostic accuracy of the LUS score to predict moderate-severe […]
» Read moreA 64-year-old previously healthy man presented with 8 weeks of progressive dyspnea on exertion and cough. Prior to presentation, the patient was able to bicycle > 60 miles per week and […]
» Read moreA 78-year-old woman was admitted to the ED with a 10-day history of diarrhea and recent onset of dry cough, fever, and asthenia. She had a medical history of obesity […]
» Read moreMore than 20% of hospitalized patients with coronavirus disease 2019 (COVID-19) develop acute respiratory distress syndrome (ARDS) requiring intensive care unit (ICU) admission. The long-term respiratory sequelae in ICU survivors […]
» Read moreThe rest of the respiratory musculature after the spontaneous breathing test to prevent extubation failures in critically ill patients needs to be further studied.Is the reconnection to mechanical ventilation (MV) […]
» Read morePD-L1 testing is feasible in a majority of specimens acquired using endobronchial ultrasound-guided needle aspiration (EBUS-TBNA).Are the outcomes of patients with advanced NSCLC treated with immune checkpoint inhibitors (ICI) on […]
» Read morePatients with malignant pleural effusions (MPEs) experience breathlessness and poor survival. Breathlessness is associated with poor survival in other conditions.Is breathlessness, measured using a visual analogue scale for dyspnoea (VASD), […]
» Read moreThe clinical benefits of cardiopulmonary rehabilitation are extensive, including improvements in health-related quality-of-life, emotional condition, physical function, and overall mortality. The coronavirus 2019 pandemic continues to negatively impact center-based cardiopulmonary […]
» Read moreThe treatment of obstructive sleep apnea (OSA) in highland residents is not established.Does nocturnal oxygen supplementation (NOS) improve sleep-related breathing disturbances, nocturnal oxygenation and cognitive performance in patients with OSA […]
» Read moreSurvivors of community-acquired pneumonia (CAP) are at increased risk of cardiovascular disease, cognitive and functional decline, and death but the mechanisms remain unknown.Do CAP survivors have evidence of increased inflammatory […]
» Read morePleural and pericardial involvement are well recognized in eosinophilic granulomatosis with polyangiitis (EGPA) but considered rare manifestations of the other ANCA-associated vasculitides (AAV).What are the frequency and clinical characteristics of […]
» Read moreSARS-CoV-2 aerosolization during noninvasive positive pressure ventilation may endanger healthcare professionals. Various circuit setups have been described in order to reduce virus aerosolization. However, these setups may alter ventilator performances.What […]
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