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The coping styles of the Sickness Insight in Coping Questionnaire (SICQ; positivism, redefinition, toughness, fighting spirit, non-acceptance) may affect the health and recovery of hospitalized critically ill patients.Do the SICQ […]
» Read moreTargeted therapies for advanced non-small cell lung cancer (NSCLC) with oncogenic drivers have caused a paradigm shift in care. Biomarker testing is needed to assess eligibility for these therapies. Pulmonologists […]
» Read moreClinicians use several measures to ascertain whether individual patients will tolerate liberation from mechanical ventilation, including the rapid shallow breathing index (RSBI).Given varied use of different thresholds, patient populations, and […]
» Read morePreclinical evidence implicates neutrophil elastase (NE) in PAH pathogenesis, and the NE inhibitor elafin is under early therapeutic investigation.Are circulating NE and elafin levels abnormal in PAH and associated with […]
» Read moreIn many studies, more than half of patients with idiopathic pulmonary fibrosis (IPF) endorse cough. In IPF (as in other conditions), when chronic, cough may be frustrating and lead to […]
» Read moreWeaning from venovenous extracorporeal membrane oxygenation (VV-ECMO) is not well studied. VV-ECMO can be discontinued when patients tolerate non-injurious mechanical ventilation (MV) during a sweep gas off trial (SGOT). However, […]
» Read moreDecannulation from venovenous extracorporeal membrane oxygenation (VV-ECMO) at the earliest and safest possible time may improve outcomes and reduce cost. Yet, there are no prospective studies comparing weaning strategies for […]
» Read moreIn pediatrics, tracheomalacia is an airway condition that causes tracheal lumen collapse during breathing and may lead to the patient requiring respiratory support. Adult subjects can narrow their glottis in […]
» Read moreCoronavirus disease 2019 (COVID-19), the disease responsible for the devastating pandemic that began at the end of 2019, has been associated with a significantly increased risk of pulmonary thrombosis, even […]
» Read moreSurvivors of critical illness have poor long-term outcomes with subsequent increases in healthcare utilisation. Less is known about the interplay between multimorbidity and long-term outcomes.How do baseline patient demographics impact […]
» Read moreCystic Fibrosis (CF) is an autosomal recessive genetic condition with multi-systemic disease manifestations, the most prominent of which occur in the respiratory system. Despite significant developments in disease understanding and […]
» Read moreDuring the first wave of the COVID-19 pandemic, shortages of ventilators and intensive care unit (ICU) beds overwhelmed healthcare systems. Whether early tracheostomy reduces the duration of mechanical ventilation and […]
» Read moreChronic obstructive pulmonary disease (COPD) medications reduce exacerbations and improve quality of life. Despite this, some individuals do not receive medications recommended by practise guidelines.How common is non-receipt of recommended […]
» Read moreThe extent by which the degree of baseline frailty, as measured using standardized multidimensional health assessments before admission to hospital, predicts survival among older adults following admission to an intensive […]
» Read moreFor patients with novel coronavirus 2019 (COVID-19) who undergo emergency endotracheal intubation, there is limited data regarding the practice, outcomes and complications of this procedure.For COVID-19 patients requiring emergency endotracheal […]
» Read moreDespite the growing role of simulation in procedural teaching, bronchoscopy training is largely experiential and occurs during patient care. The Accreditation Council for Graduate Medical Education (ACGME) sets a target […]
» Read moreCurrent guidelines recommended criteria for invasive mediastinal staging in patients with a radiologically normal mediastinum fail to identify a significant proportion of patients with occult mediastinal disease (OMD) despite leading […]
» Read moreMost patients with malignant pleural mesothelioma (MPM) present with malignant pleural effusion (MPE). There is in vitro evidence that MPE may not be a simple bystander of malignancy, but potentially […]
» Read moreAmong patients successfully resuscitated after an out-of-hospital cardiac arrest (OHCA), 10% to 15% evolve toward brain death (BD), thus becoming potential organ donors.Is it possible to establish a score for early estimation […]
» Read moreResearch on COVID-19, the cause of a rapidly worsening pandemic, has led to the observation of laboratory derangements such as a propensity towards a hypercoagulable state. However, there are currently […]
» Read moreDelirium is a serious and complex problem facing critically ill patients, their families, and the healthcare system. When it develops, delirium is associated with prolonged hospital stays, increased costs, and […]
» Read moreIncreased pleural pressure affects the mechanics of breathing of people with class III obesity (BMI > 40 kg/m2).What are the acute effects of CPAP titrated to match pleural pressure on cardiopulmonary […]
» Read moreSarcoidosis is an important member of the family of granulomatous lung diseases. Since its recognition in the late 19th century, sarcoidosis has been thought of as a disease of unknown […]
» Read moreThe COVID-19 pandemic resulted in unprecedented adjustments to intensive care unit (ICU) organization and care processes globally.Did hospital emergency responses to the COVID-19 pandemic differ depending on hospital setting; which […]
» Read moreUnilateral stimulation of the hypoglossal nerve may result in clinically valuable patency of the upper airway in well selected patients for treatment of obstructive sleep apnea. The Food and Drug […]
» Read moreThe COVID-19 pandemic resulted in unprecedented adjustments to intensive care unit (ICU) organization and care processes globally.Did hospital emergency responses to the COVID-19 pandemic differ depending on hospital setting; which […]
» Read moreUnilateral stimulation of the hypoglossal nerve may result in clinically valuable patency of the upper airway in well selected patients for treatment of obstructive sleep apnea. The Food and Drug […]
» Read moreThe short- and long-term prognosis of takotsubo syndrome (TTS) presenting with right ventricular (RV) involvement remains poorly understood.What is the incidence and clinical outcome of RV involvement in TTS?We analyzed […]
» Read moreThe short- and long-term prognosis of takotsubo syndrome (TTS) presenting with right ventricular (RV) involvement remains poorly understood.What is the incidence and clinical outcome of RV involvement in TTS?We analyzed […]
» Read moreInfant pulmonary function tests (iPFTs) in subjects with neuroendocrine cell hyperplasia of infancy (NEHI), have been shown to demonstrate significant expiratory airflow obstruction and air trapping.Can indices from iPFTs be […]
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