The effect of a quality improvement intervention on sleep and delirium in critically ill patients in a surgical intensive care unit.

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Delirium is a deleterious condition affecting up to 60% of patients in the surgical intensive care unit (SICU). Few SICU-focused delirium interventions have been implemented, including those addressing sleep-wake disruption, […]

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Provision of Smoking Cessation Resources in the Context of in-person Shared Decision Making for Lung Cancer Screening.

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Lung cancer screening (LCS) is effective at reducing mortality for high-risk smokers. Mortality benefits go beyond early cancer detection, as shared-decision making (SDM) may present a “teachable moment” to reinforce […]

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The use of intrapleural thrombolytic and/or fibrinolytic therapy via indwelling tunneled pleural catheters with or without concurrent anticoagulation usage.

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Indwelling tunneled pleural catheters are commonly used for recurrent pleural effusion management. Catheter obstruction is not uncommon, often requiring intrapleural medications instillation (i.e., alteplase) to restore flow. The safety profile […]

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Continuous pneumatic regulation of tracheal cuff pressure to decrease ventilator-associated pneumonia in mechanically ventilated trauma patients: the AGATE multicenter randomized controlled study.

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Ventilator-associated pneumonia (VAP) is the most frequent healthcare-associated infection in severely ill patients and aspiration of contaminated oropharyngeal content around the cuff of the tracheal tube is the main route […]

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The effect of reconnection to mechanical ventilation for 1 hour after spontaneous breathing trial on reintubation among patients ventilated for more than 12 hours: A randomized clinical trial.

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The rest of the respiratory musculature after the spontaneous breathing test to prevent extubation failures in critically ill patients needs to be further studied.Is the reconnection to mechanical ventilation (MV) […]

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Real-world outcomes of patients with advanced non-small cell lung cancer treated with anti-PD1 therapy on the basis of PD-L1 Results in EBUS-TBNA vs. histological specimens.

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PD-L1 testing is feasible in a majority of specimens acquired using endobronchial ultrasound-guided needle aspiration (EBUS-TBNA).Are the outcomes of patients with advanced NSCLC treated with immune checkpoint inhibitors (ICI) on […]

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Breathlessness predicts survival in patients with malignant pleural effusions: Meta-analysis of individual patient data from five randomized controlled trials.

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Patients with malignant pleural effusions (MPEs) experience breathlessness and poor survival. Breathlessness is associated with poor survival in other conditions.Is breathlessness, measured using a visual analogue scale for dyspnoea (VASD), […]

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Characterizing particulate generation during cardiopulmonary rehabilitation classes with patients wearing procedural masks.

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The clinical benefits of cardiopulmonary rehabilitation are extensive, including improvements in health-related quality-of-life, emotional condition, physical function, and overall mortality. The coronavirus 2019 pandemic continues to negatively impact center-based cardiopulmonary […]

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Effect of one night of nocturnal oxygen supplementation on highland OSA patients: a randomized, cross-over trial.

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The treatment of obstructive sleep apnea (OSA) in highland residents is not established.Does nocturnal oxygen supplementation (NOS) improve sleep-related breathing disturbances, nocturnal oxygenation and cognitive performance in patients with OSA […]

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Recommended approaches to minimize aerosol dispersion of SARS-CoV2 during noninvasive ventilatory support can deteriorate ventilator performances: a benchmark comparative study.

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SARS-CoV-2 aerosolization during noninvasive positive pressure ventilation may endanger healthcare professionals. Various circuit setups have been described in order to reduce virus aerosolization. However, these setups may alter ventilator performances.What […]

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