To identify functionally related genes associated with diabetic retinopathy (DR) risk using gene set enrichment analyses (GSEA) applied to genome-wide association study (GWAS) meta-analyses.We analyzed DR GWAS meta-analyses performed on […]» Read more
To describe the career choices of newly practicing ophthalmologists and explore factors influencing career decisions and satisfaction.A cross-sectional study was conducted using data from an electronic survey of ophthalmologists who […]» Read more
Long term outcomes in fellow eyes comparing DSAEK and DMEK for treatment of Fuchs Corneal Dystrophy.
To compare the long term results of Descemet’s stripping automated endothelial keratoplasty (DSAEK) and Descemet’s membrane endothelial keratoplasty (DMEK) in fellow eyes for treatment of Fuchs endothelial corneal dystrophy (FED).Two-centered, […]» Read more
Vision, Eye Disease, and the Onset of Balance Problems: The Canadian Longitudinal Study on Aging: Vision and Balance Problems.
To understand the relationship between visual impairment, self-reported eye disease, and the onset of balance problems.Population-based prospective cohort study METHODS: : Baseline and 3-year follow-up data were used from the […]» Read more
Anti-inflammatory Pharmacotherapy for the Prevention of Cystoid Macular Edema after Cataract Surgery.
To elucidate strategies for and controversies surrounding the use of anti-inflammatory medications after uneventful cataract surgery, with a focus on the prevention of irreversible vision loss due to cystoid macular […]» Read more
Describing the Structural Phenotype of the Glaucomatous Optic Nerve Head Using Artificial Intelligence.
To develop a novel deep-learning approach that can describe the structural phenotype of the glaucomatous ONH and can be used as a robust glaucoma diagnosis tool.Retrospective, deep-learning approach diagnosis study.We […]» Read more
Clinical features of advanced glaucoma with optic nerve head prelaminar schisis Prelaminar schisis in advanced glaucoma.
To investigate the clinical characteristics of optic nerve head (ONH) prelaminar schisis in eyes with advanced glaucoma.Cross-sectional study.One hundred sixteen eyes with advanced glaucoma (30-2 MD < -12 dB) were […]» Read more
To characterize long-term clinical outcomes of monotherapy selective laser trabeculoplasty (SLT) in Afro-Caribbean patients with open-angle glaucoma (OAG).This was a post hoc analysis of nearly 8 years (median 3.2, interquartile […]» Read more
Ultrastructural Alterations of Grafted Corneal Buttons: The Anatomic Basis for Stromal Peeling along a Natural Plane of Separation.
To examine the ultrastructure of the natural plane of separation in grafted corneas and evaluate the outcomes of stromal peeling.Interventional case series METHODS: In this multicenter study, stromal peeling was […]» Read more
Association of Optic Disc Tilt and Torsion with Open-Angle Glaucoma-Progression Risk: Meta-Analysis and Meta-Regression Analysis.
To evaluate the association of optic disc deformation with open-angle glaucoma (OAG)-progression risk.Meta-analysis and meta-regression analysis.Reports on the association of optic disc tilt and/or torsion with OAG progression published to […]» Read more
To validate a custom algorithm for automated identification and quantification of clinically relevant inflammatory choriocapillaris (CC) lesions from en face swept source optical coherence tomography (SS-OCTA) images.observational case series METHODS: […]» Read more
To investigate the characteristics and rate of central visual field loss after optic disc hemorrhages (DH).Prospective cohort study.343 eyes of 220 subjects who had at least 3 years of follow-up […]» Read more
To evaluate the incidence of vitreoretinal complications, treatment modalities, and the visual outcomes in a large cohort of eyes that underwent Boston Keratoprosthesis (KPro) implantation.Retrospective, interventional case series.132 eyes of […]» Read more
To investigate the corneal endothelium damage in Graves ophthalmopathy (GO) and its role as a promising quantitative index to evaluate GO activity.Cross-sectional study.This study included 128 eyes of 64 patients […]» Read more
COVID-19 morbidity and severity in patients with age-related macular degeneration: a Korean nationwide cohort study.
To determine the potential association of age-related macular degeneration (AMD), a representative chronic age-related degenerative disease of the retina associated with inflammation and aging, with susceptibility to SARS-CoV-2 infection and […]» Read more
Efficacy of a Single Administration of 5% Povidone-Iodine in the Treatment of Adenoviral Conjunctivitis.
To evaluate the safety and efficacy of a single, in-office administration of 5% povidone-iodine (PVP-I) compared to artificial tears (AT) for adenoviral conjunctivitis (Ad-Cs).Double-masked pilot randomized trial METHODS: Patients presenting […]» Read more
To assess the gender distribution of major ophthalmology society awards.Retrospective, observational study.The study population included award recipients from nine ophthalmological societies: American Academy of Ophthalmology (AAO), American Association for Pediatric […]» Read more
Hemiretinal Asymmetry in Peripapillary Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes.
To investigate hemiretinal asymmetry in radial peripapillary capillary vessel area density (VAD) of healthy, glaucoma suspect, and glaucoma eyes of varying severity and its diagnostic utility for glaucoma.Population-based, cross-sectional study.6 × 6-mm […]» Read more
Long-term outcome after superficial keratectomy of the abnormal epithelium for partial limbal stem cell deficiency.
To investigate the etiology and long-term surgical prognosis of the abnormal epithelium for partial limbal stem cell deficiency (LSCD), following superficial keratectomy.Retrospective, interventional case series.This single-center, retrospective study was conducted […]» Read more
Long-Term Outcomes of Boston Type I Keratoprosthesis, and Efficacy of Amphotericin B and Povidone-Iodine in Infection Prophylaxis.
To evaluate the long-term outcomes, anatomical retention and complications of Boston type I keratoprosthesis (KPro).Retrospective, interventional case series.A retrospective chart review of implantations performed January 2008-December 2017 was conducted. Risk […]» Read more
Outer retinal layer thickening predicts the onset of exudative neovascular age related macular degeneration: Outer retinal thickening predicts neovascular AMD.
To assess changes in outer retinal layer (ORL) thickness before the development of exudative macular neovascularization (MNV) in eyes with age-related macular degeneration (AMD). Retrospective observational case series Methods: Eyes with AMD […]» Read more
To compare dynamic ranges and steps to measurement floors of peripapillary and macular metrics from a complex signal-based optical microangiography (OMAGC) optical coherence tomography angiography (OCTA) device for glaucoma with […]» Read more
To report the anterior segment clinical features as well as histopathologic and histochemical characteristics of corneal findings associated with the largest reported cohort of patients with Hurler Syndrome and other […]» Read more
To identify sociodemographic factors and comorbid conditions associated with receiving keratoplasty for keratoconus (KCN) DESIGN: Retrospective, cross-sectional study METHODS: Health records of KCN patients aged <65 years from 2011 to […]» Read more
Transepithelial versus epithelium-off corneal crosslinking for progressive keratoconus: findings from a Cochrane Systematic Review.
To summarize key findings from a systematic review of the effectiveness and safety of transepithelial corneal crosslinking (CXL) compared with versus epithelium-off CXL for progressive keratoconus.Cochrane systematic review METHODS: We […]» Read more
To determine the unplanned return to OR rate within 180 days and at any time postoperatively after valved and non-valved tube shunt surgery DESIGN: : Retrospective case-control study METHODS: : […]» Read more
Vertical position of the central retinal vessel in the optic disc and its association with the site of visual field defects in glaucoma.
To investigate association between the vertical position of the central retinal vessel (CRV) within the optic nerve head (ONH) and site of visual field defects (VFDs) in glaucoma.Cross-sectional study.Vertical position […]» Read more
To determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is detectable in the aqueous of asymptomatic individuals presenting for ophthalmic surgery.Prospective cross-sectional study.Setting and Participants, All patients undergoing anterior […]» Read more
To develop a deep learning semantic segmentation network to automate the assessment of eight periorbital measurements.Development and validation of an AI segmentation algorithm METHODS: A total of 418 photographs of […]» Read more
Assessing photoreceptor status in retinal dystrophies: from high resolution imaging to functional vision.
Describe the value of integrating phenotype/genotype data, disease staging and evaluation of functional vision in patient-centered management of retinal dystrophies.1) Cross-sectional structure-function and retrospective longitudinal studies to assess the correlations […]» Read more