Gene Set Enrichment Analyses Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy.

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To identify functionally related genes associated with diabetic retinopathy (DR) risk using gene set enrichment analyses (GSEA) applied to genome-wide association study (GWAS) meta-analyses.We analyzed DR GWAS meta-analyses performed on […]

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FACTORS INFLUENCING CAREER DECISIONS AND SATISFACTION AMONG NEWLY PRACTICING OPHTHALMOLOGISTS.

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To describe the career choices of newly practicing ophthalmologists and explore factors influencing career decisions and satisfaction.A cross-sectional study was conducted using data from an electronic survey of ophthalmologists who […]

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Long term outcomes in fellow eyes comparing DSAEK and DMEK for treatment of Fuchs Corneal Dystrophy.

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To compare the long term results of Descemet’s stripping automated endothelial keratoplasty (DSAEK) and Descemet’s membrane endothelial keratoplasty (DMEK) in fellow eyes for treatment of Fuchs endothelial corneal dystrophy (FED).Two-centered, […]

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Vision, Eye Disease, and the Onset of Balance Problems: The Canadian Longitudinal Study on Aging: Vision and Balance Problems.

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To understand the relationship between visual impairment, self-reported eye disease, and the onset of balance problems.Population-based prospective cohort study METHODS: : Baseline and 3-year follow-up data were used from the […]

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Clinical features of advanced glaucoma with optic nerve head prelaminar schisis Prelaminar schisis in advanced glaucoma.

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To investigate the clinical characteristics of optic nerve head (ONH) prelaminar schisis in eyes with advanced glaucoma.Cross-sectional study.One hundred sixteen eyes with advanced glaucoma (30-2 MD < -12 dB) were […]

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Long-Term Outcomes of Selective Laser Trabeculoplasty for Open-Angle Glaucoma in the Caribbean.

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To characterize long-term clinical outcomes of monotherapy selective laser trabeculoplasty (SLT) in Afro-Caribbean patients with open-angle glaucoma (OAG).This was a post hoc analysis of nearly 8 years (median 3.2, interquartile […]

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Ultrastructural Alterations of Grafted Corneal Buttons: The Anatomic Basis for Stromal Peeling along a Natural Plane of Separation.

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To examine the ultrastructure of the natural plane of separation in grafted corneas and evaluate the outcomes of stromal peeling.Interventional case series METHODS: In this multicenter study, stromal peeling was […]

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Association of Optic Disc Tilt and Torsion with Open-Angle Glaucoma-Progression Risk: Meta-Analysis and Meta-Regression Analysis.

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To evaluate the association of optic disc deformation with open-angle glaucoma (OAG)-progression risk.Meta-analysis and meta-regression analysis.Reports on the association of optic disc tilt and/or torsion with OAG progression published to […]

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Automated Quantification of Choriocapillaris Lesion Area in Patients with Posterior Uveitis.

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To validate a custom algorithm for automated identification and quantification of clinically relevant inflammatory choriocapillaris (CC) lesions from en face swept source optical coherence tomography (SS-OCTA) images.observational case series METHODS: […]

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COVID-19 morbidity and severity in patients with age-related macular degeneration: a Korean nationwide cohort study.

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To determine the potential association of age-related macular degeneration (AMD), a representative chronic age-related degenerative disease of the retina associated with inflammation and aging, with susceptibility to SARS-CoV-2 infection and […]

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Efficacy of a Single Administration of 5% Povidone-Iodine in the Treatment of Adenoviral Conjunctivitis.

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To evaluate the safety and efficacy of a single, in-office administration of 5% povidone-iodine (PVP-I) compared to artificial tears (AT) for adenoviral conjunctivitis (Ad-Cs).Double-masked pilot randomized trial METHODS: Patients presenting […]

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Gender of Award Recipients in Major Ophthalmology Societies.

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To assess the gender distribution of major ophthalmology society awards.Retrospective, observational study.The study population included award recipients from nine ophthalmological societies: American Academy of Ophthalmology (AAO), American Association for Pediatric […]

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Hemiretinal Asymmetry in Peripapillary Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes.

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To investigate hemiretinal asymmetry in radial peripapillary capillary vessel area density (VAD) of healthy, glaucoma suspect, and glaucoma eyes of varying severity and its diagnostic utility for glaucoma.Population-based, cross-sectional study.6 × 6-mm […]

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Long-term outcome after superficial keratectomy of the abnormal epithelium for partial limbal stem cell deficiency.

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To investigate the etiology and long-term surgical prognosis of the abnormal epithelium for partial limbal stem cell deficiency (LSCD), following superficial keratectomy.Retrospective, interventional case series.This single-center, retrospective study was conducted […]

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Long-Term Outcomes of Boston Type I Keratoprosthesis, and Efficacy of Amphotericin B and Povidone-Iodine in Infection Prophylaxis.

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To evaluate the long-term outcomes, anatomical retention and complications of Boston type I keratoprosthesis (KPro).Retrospective, interventional case series.A retrospective chart review of implantations performed January 2008-December 2017 was conducted. Risk […]

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Outer retinal layer thickening predicts the onset of exudative neovascular age related macular degeneration: Outer retinal thickening predicts neovascular AMD.

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 To assess changes in outer retinal layer (ORL) thickness before the development of exudative macular neovascularization (MNV) in eyes with age-related macular degeneration (AMD). Retrospective observational case series Methods: Eyes with AMD […]

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Transepithelial versus epithelium-off corneal crosslinking for progressive keratoconus: findings from a Cochrane Systematic Review.

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To summarize key findings from a systematic review of the effectiveness and safety of transepithelial corneal crosslinking (CXL) compared with versus epithelium-off CXL for progressive keratoconus.Cochrane systematic review METHODS: We […]

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Vertical position of the central retinal vessel in the optic disc and its association with the site of visual field defects in glaucoma.

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To investigate association between the vertical position of the central retinal vessel (CRV) within the optic nerve head (ONH) and site of visual field defects (VFDs) in glaucoma.Cross-sectional study.Vertical position […]

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Presence of SARS-CoV-2 Viral RNA in Aqueous Humor of Asymptomatic Individuals.

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To determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is detectable in the aqueous of asymptomatic individuals presenting for ophthalmic surgery.Prospective cross-sectional study.Setting and Participants, All patients undergoing anterior […]

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Assessing photoreceptor status in retinal dystrophies: from high resolution imaging to functional vision.

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Describe the value of integrating phenotype/genotype data, disease staging and evaluation of functional vision in patient-centered management of retinal dystrophies.1) Cross-sectional structure-function and retrospective longitudinal studies to assess the correlations […]

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