Risk of psoriasis according to body mass index: a retrospective cohort analysis.

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Psoriasis has been linked to obesity, although there is limited data on the incidence of psoriasis according to body mass index.To compare incidence of psoriasis among patients stratified by BMI category (normal or underweight, overweight, obese-class 1, obese-class 2/3).Retrospective cohort analysis of a demographically heterogeneous sample of over 1.5 million patients in the U.S. between January 1, 2008 and September 9, 2019 RESULTS: Crude incidence of psoriasis per 10,000 person-years was 9.5 (95% CI, 9.1-10.0) among normal or underweight patients, 11.9 (95% CI, 11.4-12.4) among overweight patients, 14.2 (95% CI, 13.6-14.9) among obese class-1 patients, and 17.4 (95% CI, 16.6-18.2) among obese-class 2/3 patients. Compared to patients with BMI <25.0, those who were overweight (aHR, 1.19; 95% CI, 1.12-1.27; p

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Authors: Alexandra Norden, Sergey Rekhtman, Andrew Strunk, Amit Garg