Perforating Rheumatoid Nodule Mimicking Malignant Soft-tissue Mass of the Forearm.

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Rheumatoid nodule1, one of the most characteristic manifestations of rheumatoid arthritis (RA), occurs in approximately 30% of patients, is generally associated with positive rheumatoid factor, smoking, and high disease activity2, and occurs in some patients with specific genotypes receiving methotrexate (MTX)3 An 83-year-old woman with a history of anticitrullinated protein antibody-positive RA treated by oral MTX, as well as gout, was hospitalized for a growing tumor of her right forearm.

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Authors: Paul Ornetti, David Guillier, Geraldine Jeudy