Pain Management

Conditioned pain modulation in elite athletes: a systematic review and meta-analysis.6th August 2020
Background and aims Elite athletes reportedly have superior pain tolerances, but it is unclear if results extend to conditioned pain modulation (CPM). The aim of our study was to synthesize existing literature in order to determine whether CPM is increased in elite athletes compared to healthy controls. Methods A systematic review and random-effects meta-analysis was […]
Effects of oral alcohol administration on heat pain threshold and ratings of supra-threshold stimuli.6th August 2020
Background and aims Evidence for analgesic effects of oral alcohol consumption on heat pain has recently been documented in a placebo-controlled, randomized and double-blind design. We aimed at further investigating these effects and now set the focus on pain threshold and the ratings of supra-threshold pain to cover most of the pain range. Moreover, we […]
Association between health care utilization and musculoskeletal pain. A 21-year follow-up of a population cohort.6th August 2020
Background and aims Few studies have reported the long-term impact of chronic pain on health care utilization. The primary aim of this study was to investigate if chronic musculoskeletal pain was associated with health care utilization in the general population in a 21-year follow-up of a longitudinal cohort. The secondary aim was to identify and […]
Development of a novel zolmitriptan intracutaneous microneedle system (Qtrypta™) for the acute treatment of migraine.5th August 2020
M207 is an investigational intracutaneous microneedle therapeutic system for nonoral zolmitriptan delivery. In a Phase I trial, M207 provided faster absorption with a higher 2 h exposure than oral zolmitriptan. In the pivotal trial evaluating efficacy, tolerability and safety in moderate-to-severe migraine attacks, M207 3.8 mg was superior to placebo in providing freedom from headache pain (42 vs […]
Visual trajectory pattern as prognostic factors for neck pain.4th August 2020
A novel approach capturing both temporal variation and pain intensity of neck pain is by visual trajectory patterns. Recently, both previous and expected visual trajectory patterns were identified as stronger predictors of outcome than traditional measures of pain history and psychological distress. Our aim was to examine patient characteristics within the various previous and expected […]
Injectable PLGA-coated ropivacaine produces a long-lasting analgesic effect on incisional pain and neuropathic pain.3rd August 2020
The management of persistent postsurgical pain and neuropathic pain remains a challenge in the clinic. Local anesthetics have been widely used as simple and effective treatment for these two disorders, but the duration of their analgesic effect is short. We here reported a new poly lactic-co-glycolic acid (PLGA)-coated ropivacaine that was continuously released in vitro […]
Acetaminophen in Patients Receiving Strong Opioids for Cancer Pain.3rd August 2020
The mainstay of treatment in advanced cancer pain is opioids; however, non-opioid medications such as acetaminophen continue to be included in guidelines despite a lack of clear, convincing evidence for their use. The aim of our study was to determine if acetaminophen improves pain control or reduces opioid utilization in hospitalized patients receiving strong opioids […]
Mothers’ appraisals of injustice in the context of their child’s chronic pain: An Interpretative Phenomenological Analysis.2nd August 2020
In line with research highlighting the role of observer appraisals in understanding individuals’ pain experience, recent work has demonstrated the effects of parental child- and self-oriented injustice appraisals on child pain-related outcomes. However, research on parental injustice appraisals is in its infancy and lacks a valid and context-specific operationalization of what parental injustice appraisals of […]
Conduction velocity of the cold spinal pathway in healthy humans.1st August 2020
We aimed to investigate the conduction velocity of the cold spinal pathway in healthy humans.Using a cold stimulator consisting of micro-Peltier elements that was able to produce steep cooling ramps up to -300°C/s we recorded cold-evoked potentials after stimulation of the dorsal midline at C5, T2, T6, and T10 vertebral levels and calculated the conduction […]
DACC Resting State Functional Connectivity as a Predictor of Pain Symptoms Following Motor Vehicle Crash: A Preliminary Investigation.1st August 2020
There is significant heterogeneity in pain outcomes following motor vehicle crashes (MVCs), such that a sizeable portion of individuals develop symptoms of chronic pain months after injury while others recover. Despite variable outcomes, the pathogenesis of chronic pain is currently unclear. Previous neuroimaging work implicates the dorsal anterior cingulate cortex (dACC) in adaptive control of […]
Pelvic floor muscle training for women with lumbopelvic pain: a systematic review and meta-analysis.1st August 2020
It has been suggested that pelvic floor dysfunction may contribute to the development of lumbopelvic pain as a result of changes in trunk muscle control. However, there is limited evidence that pelvic floor muscle training (PFMT) can improve clinical outcomes in women with lumbopelvic pain.Six databases were searched for randomised controlled trials (RCTs) comparing the […]
Individuals with Back and Neck Pain on Medical Forums: What do They Mention? What Do They Fear?1st August 2020
The use of online medical forums is on the rise globally. Data scraping is a method of extracting website content using an automated computer program. We scraped users’ questions regarding back and neck pain (BNP) from popular Israeli online medical forums. We aimed to identify the sort of questions being asked about BNP, and to […]
Effect of Antipsychotics and Non-Pharmacotherapy for the Management of Delirium in People Receiving Palliative Care.30th July 2020
Evidence to support the use of antipsychotic medications for the management of delirium symptoms remains limited. The primary objective of this study was to compare the effect of antipsychotic and non-antipsychotic treatments for delirium symptoms among palliative care inpatients. Secondary outcomes were use of midazolam and overall survival. This involved retrospective analysis of medical records […]
Factors Related to Nurses’ Knowledge and Attitudes Toward Pain in Hospitals in Low-Income Areas.28th July 2020
Effective pain management is closely related to nurses’ knowledge and attitudes toward pain. Limited studies have been performed related to nurses’ knowledge and attitudes toward pain in hospitals in low-income areas.This study surveyed the knowledge and attitudes of nurses toward pain management in county hospitals from low-income areas in Hunan Province, China.The study included 4,668 […]
The acquisition and generalization of fear of touch.27th July 2020
Objectives Contemporary fear-avoidance models of chronic pain posit that fear of pain, and overgeneralization of fear to non-threatening stimuli is a potential pathway to chronic pain. While increasing experimental evidence supports this hypothesis, a comprehensive investigation requires testing in multiple modalities due to the diversity of symptomatology among individuals with chronic pain. In the present […]
The Effect of Position Support During Orthopedic Surgery on Postoperative Pain: A Randomized Controlled Trial.27th July 2020
Positional pain affect the patient’s healing process after the operation. Anti-pressure positioning pads are medical products used to support the patient positioning during surgical procedures.The aim of the study was to examine pain related to positioning when anti-pressure gel pads and current visoelastic sponge support options are used during orthopedic surgical cases.The randomized controlled experimental […]
Virtual reality for acute and chronic pain management in adult patients: a narrative review.27th July 2020
Virtual reality is a computer-generated environment that immerses the user in an interactive artificial world. This ability to distract from reality has been utilised for the purposes of providing pain relief from noxious stimuli. As technology rapidly matures, there is potential for anaesthetists and pain physicians to incorporate virtual reality devices as non-pharmacological therapy in […]
Pain perception during colonoscopy in relation to gender and equipment: a clinical study.25th July 2020
Objectives A trend for gender-related differences in pain perception during colonoscopies has previously been observed. No consecutive clinical studies have been conducted to confirm such a relation. We aimed to investigate gender-related differences during the colonoscopy procedure, and the impact of endoscopic equipment and psychological factors on pain management. Methods In a consecutive clinical study, […]
Preliminary validity and test-retest reliability of two depression questionnaires compared with a diagnostic interview in 99 patients with chronic pain seeking specialist pain treatment.25th July 2020
Objectives Depression symptomatology is highly prevalent in patients with chronic pain, but accurate identification of major depression may be challenged due to time constraints and diagnostic interviews are therefore not routinely performed in clinical practice. Assessment of depression may be facilitated through the use of full-length depression screening questionnaires with acceptable construct validity and test-retest […]
En pointe: dancers report their pain less variably than do controls.24th July 2020
The subjective nature of pain and the lack of a gold standard for objective measurement hinders effective assessment, diagnosis, and treatment. Some individuals, such as professional dancers, are better in assessing and reporting bodily sensations. This observational study aimed to assess whether dancers report their pain less variably, than other people do. After consenting, subjects […]
Development and preliminary validation of the Chronic Pain Acceptance Questionnaire for Clinicians.24th July 2020
Background and Aims Higher chronic pain acceptance is associated with lower pain and disability. Clinician beliefs are associated with patients’ beliefs. This study therefore aimed to develop the Chronic Pain Acceptance Questionnaire for Clinicians (CPAQ-C) to measure clinicians’ beliefs regarding the importance of levels of acceptance in patients with chronic pain, and to examine the […]
Static mechanical allodynia in post-surgical neuropathic pain after breast cancer treatments.23rd July 2020
Objectives Static mechanical allodynia (SMA), i. e., pain caused by normally non-painful static pressure, is a prevalent manifestation of neuropathic pain (NP). Although SMA may significantly affect the patient’s daily life, it is less well studied in the clinical context. We aimed to characterize SMA in women with chronic post-surgical NP (CPSNP) after breast cancer surgery. […]
Obesity and Multisite Pain in the Lower Limbs: Data from the Osteoarthritis Initiative.23rd July 2020
Although several studies investigated the relationship between obesity, osteoarthritis, and pain, no study examined the association between obesity and multijoint pain in the lower limbs. The purpose of this study was to address this gap.This cross-sectional study was performed in Riyadh, Saudi Arabia, between March and April 2019. In this study, a total of 4,661 […]
Effects of Scrambler Therapy in Patients with Failed Back Surgery Syndromes and Factors Associated with Depression Affecting Pain before and after the Therapy.23rd July 2020
To report the effects of scrambler therapy in patients diagnosed with failed back surgery syndromes and to analyze the factors affecting pain before and after the therapy.This study included 26 patients (12 males and 14 females). The Oswestry Disability Index (ODI) and Brief Pain Inventory (BPI) before and after scrambler therapy, Beck Depression Inventory (BDI) […]
A randomized controlled pilot study comparing the efficacy of Pulsed Radiofrequency combined with Exercise versus Exercise in pain relief and functional improvement for chronic knee osteoarthritis.22nd July 2020
To compare the long-term efficacy between pulsed radiofrequency (PRF) combined with passive stretching (PRF-PS) exercise and PS exercise alone in reducing pain and improving quadriceps muscle strength and knee function.Sixty-two participants were randomly assigned with 1:1 allocation to PRF-PS exercise group or PS exercise group. Level of pain, muscle strength and knee function were assessed […]
A novel clinical applicable bed-side tool for assessing conditioning pain modulation: proof-of-concept.22nd July 2020
Background and aims In recent years, focus on assessing descending pain modulation or conditioning pain modulation (CPM) has emerged in patients with chronic pain. This requires reliable and simple to use bed-side tools to be applied in the clinic. The aim of the present pilot study was to develop and provide proof-of-concept of a simple […]
The effect of periaqueductal gray’s metabotropic glutamate receptor subtype 8 activation on locomotor function following spinal cord injury.22nd July 2020
Background and aims The pathophysiology of spinal cord injury is very complex. One of the debilitating aspects of spinal cord injury in addition to pain is a defect in motor function below the lesion surface. In this study, we tried to assess the modulatory effect of (S)-3,4-Dicarboxyphenylglycine (DCPG), a metabotropic glutamate receptor subtype 8 (mGluR8) […]
Validation of the Arabic Version of the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool.22nd July 2020
Chemotherapy-induced peripheral neuropathy results in multidimensional neurological and muscular symptoms, which interfere with the patients’ daily life.Examine the psychometric properties of the Arabic version of the chemotherapy-induced peripheral neuropathy assessment tool (CIPNAT) among adult cancer patients.A descriptive study design was used. A convenience sample of 210 patients was assigned to two groups: 135 who received […]
Relationships between psychological, sleep, and physical activity measures and somatosensory function in people with peripheral joint pain: a systematic review and metaanalysis.22nd July 2020
Alteration in somatosensory function has been linked to pain experience in individuals with joint pain. This systematic review aimed to establish the level of evidence of associations between psychological, social, physical activity, and sleep measures andsomatosensory function that assessed via quantitative sensory testing (QST) among individuals withjoint pain.A comprehensive literature search was conducted in six […]
Acceptance and Commitment Therapy for Primary Headache Sufferers: A Randomized Controlled Trial of Efficacy.20th July 2020
Prevention of headaches via avoidance of triggers remains the main behavioral treatment suggestion for headache management despite trigger avoidance resulting in increases in potency, lifestyle restrictions, internal locus of control decreases, pain exacerbation and maintenance. New approaches, such as Acceptance and Commitment Therapy (ACT), instead emphasize acceptance and valued living as alternatives to avoidance. Though […]
Placebos in chronic pain: evidence, theory, ethics, and use in clinical practice.20th July 2020
Despite their ubiquitous presence, placebos and placebo effects retain an ambiguous and unsettling presence in biomedicine. Specifically focused on chronic pain, this review examines the effect of placebo treatment under three distinct frameworks: double blind, deception, and open label honestly prescribed. These specific conditions do not necessarily differentially modify placebo outcomes. Psychological, clinical, and neurological […]
Development and Pilot Evaluation of an Educational Tool for the FLACC Pain Scale.20th July 2020
The FLACC (Face, Legs, Activity, Cry, Consolability) pain scale is commonly used for pediatric pain assessment; however, no online educational tool exists to facilitate the use of the scale.This study aimed to develop an online educational tool and evaluate its effect on nurse knowledge, user confidence, and scoring accuracy.In phase 1, semistructured interviews were conducted […]
Pain Management in Home Health Care: Relationship With Dementia and Facility Admissions.19th July 2020
Pain is common yet under-studied among older Medicare home health (HH) patients with Alzheimer’s disease and related dementias (ADRD).Examine (1) the association between ADRD and severe pain in Medicare HH patients; and (2) the impact of severe pain and ADRD on unplanned facility admissions in this population.Analysis of the Outcome and Assessment Information Set (OASIS) […]
Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial.18th July 2020
This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. In seven academic centers, 550 cariously exposed pulps were included and randomly allocated into PMTA (n = 188), PCEM (n = 194), or RCT (n = 168) arms. Preoperative “Pain […]
Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial.18th July 2020
This pilot study aims to evaluate the effectiveness and safety of acupuncture in the treatment of chemotherapy-induced peripheral neuropathy (CIPN).This study was a pilot randomized controlled trial, which was conducted with cooperation between Beijing University of Chinese Medicine (BUCM), China, and Tehran University of Medical Science (TUMS), Iran. Forty participants with CIPN were randomly assigned […]
Association between Chronic Pain and Diabetes/Prediabetes: A Population-Based Cross-Sectional Survey in Saudi Arabia.18th July 2020
Diabetes is a debilitating chronic health condition that is associated with certain pain syndromes. The present study sought to evaluate chronic pain and its association with diabetes mellitus at a population level.A population-based cross-sectional questionnaire survey study was conducted in Al-Kharj, Saudi Arabia, from January 2016 to June 2016. Participants from both private and governmental […]
Predictors of Mucosal and Muscle Pain in Vulvodynia: A Cross-Sectional Analysis from the National Vulvodynia Registry.18th July 2020
Diagnostic criteria for provoked vestibulodynia (PVD) rely on mucosal pain in the vulvar vestibule, with less emphasis on pain from pelvic floor muscles. It is unknown how psychosocial variables associated with PVD are differentially associated with mucosal versus muscle pain. Analysis of data from the National Vulvodynia Registry (n=202) revealed several factors associated with increased […]
Sex Difference in Trigeminal Neuropathic Pain Response to Exercise: Role of Oxidative Stress.18th July 2020
Orofacial chronic neuropathic pain commonly occurs following trigeminal nerve injuries. We investigated whether swimming exercise can reduce trigeminal neuropathic pain through improving antioxidant capacity.Twenty-eight Wistar rats of either sex and 180-220 grams were divided into 4 groups as sham, neuropathy, neuropathy + single bout exercise, and neuropathy + 2 weeks of exercise. Trigeminal neuropathy was carried out through chronic […]
Distraction from pain: The role of selective attention and pain catastrophizing.17th July 2020
Previous research has demonstrated the efficacy of cognitive engagement in reducing concurrent pain. However, little is known about the role of individual differences in inhibitory control abilities and negative pain-related cognitions in modulating the magnitude of this type of distraction from pain.In a pain distraction paradigm, 41 participants completed a working memory task with both […]
Pain perception in chronic knee osteoarthritis with varying levels of pain inhibitory control: an exploratory study.16th July 2020
Background and aims Pain is a disabling symptom in knee osteoarthritis (KOA) and its underlying mechanism remains poorly understood. Dysfunction of descending pain modulatory pathways and reduced pain inhibition enhance pain facilitation in many chronic pain syndromes but do not fully explain pain levels in chronic musculoskeletal conditions. The objective of this study is to […]
Trends in Opioid Use in a Cohort of Patients with Rheumatoid Arthritis.16th July 2020
The objective was to determine the trend in the use of opioid analgesics in a cohort of patients diagnosed with and treated for rheumatoid arthritis (RA) in 24 cities in Colombia. This retrospective cohort study included adult patients diagnosed with RA, which was managed in a specialized institution in Colombia between January 2011 and December […]
Sick leave due to back pain, common mental disorders, and disability pension: Common genetic liability.16th July 2020
Back pain and common mental disorders are often comorbid and known risk factors for future disability pension. However, the reason for the covariation is not known. The aim was to investigate the common genetic and environmental influences on the covariation between sick leave due to back pain, sick leave due to common mental disorders and […]
Effect of patient characteristics on reported outcomes over 12 months following lumbar radiofrequency ablation: a retrospective review of 500 patients.13th July 2020
Low back pain is the leading cause of years lost to disability worldwide. Approximately 15-45% of chronic low back pain is due to facet joint arthropathy. Currently, there are no large-scale retrospective studies that investigate long-term clinical predictors of success in individuals receiving radiofrequency ablation (RFA) of the medial branches for facet joint arthropathy.To determine […]
Socioeconomic disparities in the utilization of spinal cord stimulator therapy in chronic pain patients.13th July 2020
Spinal cordstimulator (SCS) therapies are used in the management of patients with complex regional pain syndrome I (CRPS I) and failed back surgery syndrome (FBSS). The purpose of this study is to investigate the racial and health insurance inequalities with SCS therapy in chronic pain patients with CRPS I and FBSS.Chronic pain patients with a […]
Systematic review and meta-analysis suggest strength training and workplace modifications may reduce neck pain in office workers.13th July 2020
Neck pain is a burdensome musculoskeletal disorder in office workers. Workplace interventions aim to prevent and minimise the effect of neck pain and improve work quality. However, the summed effect of workplace interventions on neck pain in office workers remains unclear. This systematic review with meta-analysis and meta-regression evaluated the summed effect of workplace interventions […]
Trajectories of post-surgical pain in infants admitted to neonatal intensive care.13th July 2020
The aim of this study was 1) to statistically identify distinct trajectories of pain following surgery in infants less than six months of age, and 2) to compare these trajectories to descriptions of chronic pain in infants in the neonatal intensive care unit (NICU).This was a retrospective medical record review of infants admitted to a […]
Nurse’s Evaluation of a Pain Management Algorithm in Intensive Care Units.12th July 2020
Many patients have memories of pain during intensive care unit stay. To improve pain management, practice guidelines recommend that pain management should be guided by routine pain assessment and suggest an assessment-driven, protocol-based, stepwise approach. This recommendation prompted the development of a pain-management algorithm.Evaluate the feasibility and clinical utility of this algorithm.A descriptive survey.One medical/surgical intensive […]
Dysmenorrhea and Associated Factors among Polish Women: A Cross-Sectional Study.11th July 2020
The aim of the research was to conduct an assessment of the prevalence of dysmenorrhea and associated factors among Polish women. Patients and Methods. A cross-sectional study was conducted among Polish women using an online questionnaire. The mean age of the participants was 23 ± 4 years. Out of the total of 1,317 women who took part […]
Sustained perturbation in functional connectivity induced by cold pain.10th July 2020
Functional connectivity (FC) perturbations have been reported in multiple chronic pain phenotypes, but the nature of reported changes varies between cohorts and may relate to the consequences of living with chronic-pain related comorbidities, such as anxiety, and depression. Healthy volunteer studies provide opportunities to study the effects of tonic noxious stimulation independently of these sequelae. […]
Prevalence and Correlates of Frailty in Community-Dwelling Older Adults with Chronic Pain: A Cross-Sectional Study.9th July 2020
Frailty is a frequent health condition in older adults of decreased functional reserve that leads to vulnerability to internal and external stressors. It has been associated with chronic pain, which is a common, costly and incapacitating condition in older adults.To describe frailty status in a sample of community-dwelling older adults with chronic pain attending a […]
Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.9th July 2020
Tofersen is an antisense oligonucleotide that mediates the degradation of superoxide dismutase 1 (SOD1) messenger RNA to reduce SOD1 protein synthesis. Intrathecal administration of tofersen is being studied for the treatment of amyotrophic lateral sclerosis (ALS) due to SOD1 mutations.We conducted a phase 1-2 ascending-dose trial evaluating tofersen in adults with ALS due to SOD1 […]
Observation of Emergency Room Nurses Managing Pediatric Pain: Care to Be Given… Care Given….8th July 2020
Although pain undeniably has negative consequences, pain management often remains suboptimal, particularly in the pediatric population in the emergency room (ER).In this observational study using qualitative and quantitative methods, we investigated everyday adherence to current nursing best-practice pediatric guidelines in the ER paying particular attention to the interaction between children, parents, and nurses.An adapted version […]
Dexamethasone suppresses radicular pain through targeting L-PGDS/PI3K/Akt pathway in rats with lumbar disc herniation.8th July 2020
Lumbar disc herniation (LDH) is a frequently occurring disease with unknown etiology, which makes treatment a challenge. The aim of this study was to analyze the effects of dexamethasone on LDH and elucidate the underlying mechanisms.LDH rat model was established by nucleus pulposus (NP) implantation. The activity of the L-PGDS/PI3K/Akt axis was evaluated by Western […]
A More Comfortable Method of Skin Prick Testing in Children Ages 0-2 to Decrease Symptoms of Pain.7th July 2020
Skin prick testing (SPT) is the best initial diagnostic method for individuals of all ages who have potential allergies.We aimed to investigate if recent breastfeeding has any effect on reducing the pain of children before SPT.Prospective, randomized, single-blinded study.Academic hospital specialized in pediatrics.Sixty-four out of seventy-five children requiring SPT within ages 0-2 were included.All participants […]
Transcranial direct current stimulation and visual illusion effect according to sensory phenotypes in patients with spinal cord injury and neuropathic pain.7th July 2020
Treatment of neuropathic pain (NP) in patients with spinal cord injury (SCI) remains a major challenge. The aim of the present study is to investigate if the effect of transcranial direct current stimulation (tDCS) combined with visual illusion (VI), following a previously published protocol, has differential effects on pain-related sensory symptoms according to sensory phenotypes […]
Radiofrequency thoracic sympathectomy for sympathetically maintained chronic post-mastectomy pain, a preliminary report: six months results.6th July 2020
Evaluation of the analgesic efficacy of radiofrequency thoracic sympathectomy for sympathetically maintained post-mastectomy pain syndrome (PMPS).Patients with PMPS, randomized to group TS, (n = 33) received radiofrequency thoracic sympathectomy or group SHAM, (n = 33). Post-operative pain treatment consisted of duloxetine, pregabalin, and tramadol for both groups. The outcome variables were the percentage of patients […]
Effects of anaesthesia method and tourniquet use on recovery following total knee arthroplasty: a randomised controlled study.5th July 2020
We investigated the effects of spinal and general anaesthesia and surgical tourniquet on acute pain and early recovery after total knee arthroplasty (TKA).Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia with or without tourniquet. The primary outcome was patient-controlled i.v. oxycodone consumption over 24 postoperative hours.Results […]
Systemic inflammatory markers in neck pain: a systematic review with meta-analysis.5th July 2020
Mechanisms underpinning symptoms in non-traumatic neck pain (NTNP) and whiplash-associated disorder (WAD) are not comprehensively understood. There is emerging evidence of systemic inflammation in musculoskeletal pain conditions, including neck and back pain. The aim of this systematic review was to determine if raised blood inflammatory markers are associated with neck pain.MEDLINE, EMBASE, Cochrane Library, CINAHL […]
Movement, posture and low back pain. How do they relate? A replicated single-case design in 12 people with persistent, disabling low back pain.5th July 2020
Movement and posture are commonly believed to relate to non-specific low back pain (NSLBP). While people with NSLBP appear to move and posture themselves differently from those without NSLBP, changes in movement and posture infrequently relate to improvements in NSLBP when analysed at a group-level. Additionally, little is known about how movement or posture change […]
Spinal manipulation for the management of cervicogenic headache: a systematic review and meta-analysis.5th July 2020
Spinal manipulative therapy (SMT) is frequently used to manage cervicogenic headache (CGHA). No meta-analysis has investigated the effectiveness of SMT exclusively for CGHA.Evaluate the effectiveness of SMT for CGHA. Databases and Data Treatment Five databases identified randomized controlled trials comparing SMT with other manual therapies. The PEDro scale assessed the risk-of-bias. Pain and disability data […]