Myoedema with pseudohypertrophic hypothyroid myopathy (Hoffman’s syndrome).

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Myoedema is an under-recognised neurological sign that can help the bedside diagnosis of metabolic or endocrine myopathies. Myoedema together with pseudo-hypertrophy make a likely diagnosis of hypothyroid myopathy, and its identification may avoid unnecessary investigations.

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Authors: Aastha Takkar, Julie Sachdeva, Nikhil Vojjala, Vivek Lal