Mometasone furoate for children with asthma: A meta-analysis.
Mometasone furoate shows some potential in treating paediatric asthma. We conduct a systematic review and meta-analysis to explore the efficacy and safety of mometasone furoate for paediatric asthma.We have searched PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through October 2019 for randomized controlled trials (RCTs) assessing the effect of mometasone furoate versus placebo for paediatric asthma. This meta-analysis is performed using the random-effects model.Four RCTs are included in the meta-analysis. Overall compared to placebo for paediatric asthma, mometasone furoate is associated with substantially increased predicted expiratory volume in 1 s (FEV1) (mean difference (MD) = 7.53; 95% confidence interval (CI) = 7.02 to 8.04; P