Measuring atopic eczema symptoms in clinical practice: The First Consensus Statement from the Harmonising Outcome Measures for Eczema in Clinical Practice Initiative.
Measuring patient-centered outcomes in clinical practice is valuable for monitoring patients and advancing real-world research. A new initiative from the Harmonising Outcome Measures for Eczema (HOME) group aims to recommend what might be recorded for atopic eczema (AE) patients in routine clinical care.Prioritize outcome domains to measure AE in clinical practice and select valid and practical outcome measurement instruments for the highest-priority domain.An online survey of HOME members identified and ranked 21 possible health-domains. Suitable instruments were then selected for the top-prioritized domain at the HOME VI meeting, using established consensus processes informed by systematic reviews of instrument quality.Patient-reported symptoms was the top-prioritized domain. Based on psychometric properties and feasibility, there was consensus that the recommended instruments to measure AE symptoms in clinical practice are the Patient-Oriented Eczema Measure (POEM) and/or the Patient-Oriented SCORing Atopic Dermatitis index (PO-SCORAD). The Numerical Rating Scale for itch received support pending definition and validation in AE.Following the first step of the HOME Clinical Practice initiative, we endorse using the POEM, the PO-SCORAD, or both for measuring AE symptoms in clinical practice. Additional high-priority domains for clinical practice will be assessed at subsequent HOME meetings.