Long-term Outcomes of Juvenile Onset Recurrent Respiratory Papillomatosis with Pulmonary Involvement.

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To investigate the clinical characteristics and long-term outcomes of juvenile onset recurrent respiratory papillomatosis (JORRP) with or without pulmonary involvement.A group of patients with JORRP who had clinical course over an extended period of time (at least 5 years) in the Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital were included in this retrospective study. Lung/bronchus involvement was revealed by lung imaging. Data on mortality rate, frequency of surgical interventions, and age of disease onset were collected and analyzed.The 192 patients (107 male and 85 female) included had a median [quartiles] age of JORRP onset of 2 [1, 4] years, and median follow-up duration of 10 [7, 13] years; 17 patients (8.9%) had papilloma with bronchial and pulmonary involvement 7.0 [4.0, 12.5] years after the onset of the disease. Compared to patients without lung involvement, patients with lung involvement had a younger age of disease onset (P = .001), higher frequency of surgical interventions (P

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This is an abstract of the clinical research article “Long-term Outcomes of Juvenile Onset Recurrent Respiratory Papillomatosis with Pulmonary Involvement.” This clinical research article was published in the medical journal The Laryngoscope on 2021-01-07 and has been categorised as belonging to the clinical specialty of ENT. To read the full clinical research article or obtain a PDF (if available) use the links directly above. To discover more of the latest ENT clinical research articles from the medical journal The Laryngoscope please click the link below. For more of the latest ENT research articles from other leading medical journals click the link that says ENT next to the stethoscope icon at the top of the page. You can further filter clinical research articles by sub-specialties within ENT using the navigation menu at the top of the page.