Kawasaki disease for the pediatric dermatologist: Skin manifestations and new insights into the pathophysiology.
Early diagnosis of Kawasaki (KD) disease is critical to promptly initiate treatment and avoid cardiac complications. All children have fever accompanied by clinical signs with 4 of the 5 classific criteria for complete KD being mucocutaneous, thus creating an important role for dermatologists. Moreover, dermatologists must be familiar with other dermatological findings, not included in the American Heart Association classification criteria, which can support the diagnosis particularly in incomplete forms of the disease. We review herein skin manifestations described in KD and perform an overview of pathophysiological advances and new treatments.