Evaluation of Cardiac Troponin I and N-Terminal pro B – Type Natriuretic Peptide Serum Levels in Patients with Alopecia Areata.

Please login or register to bookmark this article
Bookmark this %label%

Alopecia areata (AA) is a recurrent, immune mediated, hair loss disorder. It is associated with other autoimmune disorders which carry high risk of cardiovascular diseases (CVDs). However, cardiovascular comorbidity associated with AA was poorly investigated. Cardiac troponin I (cTnI) is a biomarker of myocardial ischemia and inflammation. N-terminal pro B- type natriuretic peptide (NT pro BNP) is used in diagnose of congestive heart failure. This study was conducted to assess serum level of both markers by enzyme linked immune-sorbent assay in 44 AA patients compared to 44 control subjects. All participants didn’t suffer from CVDs or risk factors or other diseases associated with elevation of both markers. The study revealed that serum levels of both markers were significantly higher in AA patients compared to controls (P< 0.001). Thus, the inflammatory milieu encountered in AA may be associated with subtle myocardial inflammation that causes elevation of levels of both markers.

Get PDF with LibKey
View the article @ Clinical and experimental dermatology (sign-in may be required)