Diagnostic yield and appropriate indication of upper endoscopy in Jordanian children.

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Upper endoscopy is an essential tool for diagnosing pediatric gastrointestinal issues. This study aimed to assess the indications, diagnostic yields, concordance between histopathological and endoscopic findings and suitability of upper endoscopies performed at a tertiary university hospital in Jordan.Hospital records of children who underwent upper endoscopy were retrospectively reviewed. Demographics, endoscopic details (e.g., indications, findings and any complications), and histopathological findings were collected. The relationship between endoscopic findings and histopathological abnormalities was reported.The study included 778 patients (age, 92.5 ± 54.5 months; 380 girls, 48.8%). The most common age group was children younger than 60 months (273 patients, 34.3%). The most common indication for endoscopy was abdominal pain, followed by vomiting and failure to thrive or weight loss. Normal upper endoscopy was reported in 411 patients (52.8%). Age below 60 months, abdominal pain, dysphagia/odynophagia, and heartburn were predictive of abnormal endoscopy in multivariate analysis with p-value 0.000, 0.048, 0.001 and 0.01 respectively. Abnormal endoscopy showed 67.3% sensitivity and 69.9% specificity to predict histopathological abnormalities. Of those performed, 13.6% endoscopies were described as inappropriate indication. The suitability of the procedure was a sensitive predictor for abnormal endoscopic and histopathological findings.Abdominal pain is the most common indication for upper endoscopy in our population. It is associated with a higher chance of abnormal endoscopy. Concordance between endoscopic and histopathological findings is not high. Normal endoscopic findings shouldn`t discourage the endoscopist from obtaining tissue biopsies. Considering more biopsies may improve pathological detection rates. Compliance with established endoscopy guidelines may reduce unnecessary procedures.

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This is an abstract of the clinical research article “Diagnostic yield and appropriate indication of upper endoscopy in Jordanian children.” This clinical research article was published in the medical journal BMC pediatrics on 2021-01-06 and has been categorised as belonging to the clinical specialty of Paediatrics. To read the full clinical research article or obtain a PDF (if available) use the links directly above. To discover more of the latest Paediatrics clinical research articles from the medical journal BMC pediatrics please click the link below. For more of the latest Paediatrics research articles from other leading medical journals click the link that says Paediatrics next to the stethoscope icon at the top of the page. You can further filter clinical research articles by sub-specialties within Paediatrics using the navigation menu at the top of the page.