A meta-analysis of alcohol consumption and the risk of brain tumours.

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Alcohol is capable of traversing the blood-brain barrier and is thus a possible risk factor for brain cancer. Several epidemiological studies have been published on the issue, a number of […]

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The volume effect in paediatric oncology: a systematic review.

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For several adult cancer types, there is evidence that treatment in high volume hospitals, high case volume providers, or in specialised hospitals leads to a better outcome. The aim of […]

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TRK inhibitors in TRK fusion-positive cancers.

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TRK fusions are oncogenic drivers of various adult and paediatric cancers. The first-generation TRK inhibitors, larotrectinib and entrectinib, were granted landmark, tumour-agnostic regulatory approvals for the treatment of these cancers […]

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