Effect of Regional Citrate Anticoagulation vs Systemic Heparin Anticoagulation During Continuous Kidney Replacement Therapy on Dialysis Filter Life Span and Mortality Among Critically Ill Patients With Acute Kidney Injury: A Randomized Clinical Trial.

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Although current guidelines suggest the use of regional citrate anticoagulation (which involves the addition of a citrate solution to the blood before the filter of the extracorporeal dialysis circuit) as […]

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Bi-layered composite scaffold for repair of the osteochondral defects.

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Osteochondral defect presents a big challenge for clinical treatment. This study aimed to construct a bi-layered composite Chitosan/Chitosan-β-Tricalcium phosphate (CS/CS-β-TCP) scaffold and repair the rat osteochondral defect.The bi-layered CS/CS-β-TCP scaffold […]

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Analyzing Factors Affecting Quality of Life in Patients Hospitalized with Chronic Wound.

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Studies have reported associations between health-related quality of life(HRQOL), social support, and mental stress of patients with chronic wound, while the causal relationship is unclear and little is known about […]

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Galectin-1 Production is Elevated in Hypertrophic Scar.

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Upon healing, burn wounds often leave hypertrophic scars (HTSs) marked by excess collagen deposition, dermal and epidermal thickening, hypervascularity, and an increased density of fibroblasts. The Galectins, a family of […]

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Efficacy of low-level light therapy for improving healing of diabetic foot ulcers: A systematic review and meta-analysis of randomised controlled trials.

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Diabetic foot ulcers are prevalent among patients with diabetes and negatively affect mortality and life expectancy. This study aimed to synthesise and systematically review the best evidence to assess the […]

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Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

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In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is […]

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High-voltage pulsed electric fields eliminate Pseudomonas aeruginosa stable infection in a mouse burn model.

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The incidence of severe infectious complications after burn injury increases mortality by 40%. However, traditional approaches for managing burn infections are not always effective. High-voltage pulsed electric field (PEF) treatment […]

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Efficacy of Surgical Excision and Brachytherapy in the Treatment of Keloids: A Retrospective Cohort Study.

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To demonstrate the efficacy of a protocol combining surgical excision and high-dose-rate brachytherapy for treatment of keloids.The authors performed a unicentric retrospective cohort study between 2013 and 2018. The minimum […]

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A Quality Improvement Project Comparing Two Treatments for Deep-Tissue Pressure Injuries to Feet and Lower Legs of Long-term Care Residents.

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To retrospectively examine clinical outcomes from a feasibility study that compared two treatment options for deep-tissue pressure injuries (DTPIs), including the clinical indicators increasing the risk of deteriorating DTPIs among […]

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Informed Application of the Standards on Support Surface Performance for Clinically Meaningful Use.

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The Support Surface Standards Initiative (S3I) has evolved with the goal of standardizing language and performance evaluation of support surfaces. There is a consumer need for education about support surface […]

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Electric Stimulation as an Effective Adjunctive Therapy for Diabetic Foot Ulcer: A Meta-analysis of Randomized Controlled Trials.

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To evaluate the effectiveness of electric stimulation (ES) for diabetic foot ulcer (DFU) treatment.The authors searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov databases for randomized clinical […]

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Treatment of Superficial Incision Dehiscence after Abdominal Surgery by Z-Plasty: A Retrospective Case Series.

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To explore the treatment of superficial incision dehiscence after abdominal surgery by Z-plasty combined with negative-pressure wound therapy.A retrospective study was performed on seven patients with superficial abdominal incision dehiscence […]

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Prevención de lesiones por presión: conocimientos y actitudes del personal de enfermería.

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Identify, analyse and summarise the empirical evidence on nurses’ knowledge and attitudes towards pressure ulcer (PU) prevention.A systematic literature review on articles published between 2008 y 2019 was performed following […]

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Manejo de heridas traumáticas de difícil cicatrización con colgajos microvasculares.

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Present different flap alternatives when performing microvascular free-flap reconstruction in acute hard-to-heal wounds.A retrospective review of patients whose acute hard-to-heal wounds were treated with microvascular free-flap reconstruction. Data on demographics, […]

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Protocolo de tratamiento de heridas con apósito de hidrofibra reforzada, con plata iónica al 1,2%, potenciado con EDTA y cloruro de bencetonio para evitar la recurrencia de biopelícula.

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Present a treatment protocol to avoid biofilm reformation in hard-to-heal wounds, using a hydrofiber dressing with 1.2% ionic silver, ethylenediaminetetraacetic acid and benzethonium chloride.A retrospective, descriptive and analytic study on […]

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Pressure Injury Prevention and Wound Management for the Patient Who Is Actively Dying: Evidence-Based Recommendations to Guide Care.

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Preventing pressure injuries and wound deterioration can be challenging for the patient at the end of life. Pressure injuries are often deemed unavoidable when a patient is actively dying; however, […]

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Limited Treatment Options for Diabetic Wounds: Barriers to Clinical Translation Despite Therapeutic Success in Murine Models.

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Millions of people worldwide suffer from diabetes mellitus and its complications, including chronic diabetic wounds 1. To date, there are few widely successful clinical therapies specific to diabetic wounds beyond […]

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