Use of a novel silicone-acrylic drape with negative pressure wound therapy in anatomically challenging wounds.

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Negative pressure wound therapy (NPWT) utilises a polyurethane drape with acrylic adhesive over foam dressings to create a seal. In anatomically challenging areas, ancillary products are frequently used. Additionally, health […]

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A new surgical approach of direct perineal wound full-thick closure for perineal wound of abdominoperineal resection for rectal carcinoma: A prospective cohort trial.

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Perineal wound complications after APR have high morbidity in the colorectal surgical department. Although some approaches have been figured out to solve this clinical focus, the outcomes are still not […]

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The use of vascularised muscle flaps for treatment or prevention of wound complications following arterial surgery in the groin.

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Wound complications following arterial surgery in the groin are relatively common and can result in significant morbidity and mortality. Vascularised muscle flaps (VMF) may be used as an adjunct to […]

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Comparison of comparable scald and contact burns in a porcine model: A preliminary report.

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Whether the depth and healing of scalds and contact burns are similar is controversial. Due to water’s greater heat capacity, we hypothesized that when exposed to similar temperatures and durations […]

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Metabolomics: Impact of comorbidities and inflammation on sickness behaviors for individuals with chronic wounds.

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Approximately 6.5 million people in the United States suffer from chronic wounds. The chronic wound population is typically older and is characterized by a number of comorbidities associated with inflammation. […]

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A collaborative approach in patient education for diabetes foot and wound care: A pragmatic randomised controlled trial.

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Foot care education is an important strategy in reducing lower limb complications. There is evidence that contemporary communication approaches can improve patient education outcomes. To inform the potential of such […]

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Alcohol consumption does not increase the risk of surgical wound complications in breast cancer patients.

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Alcohol consumption, despite influencing several organic processes, has been scarcely studied regarding the risk of developing surgical wound complications after surgical breast cancer treatment. The aim of this study was […]

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Negative pressure wound therapy with instillation and dwell time (NPWTi-d) with V. A. C. VeraFlo in traumatic, surgical, and chronic wounds-A helpful tool for decontamination and to prepare successful reconstruction.

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For nearly two decades, Negative Pressure Wound Therapy (NPWT) has been used for temporary wound coverage as well as wound bed preparation. The addition of instillation and dwell time as […]

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Effectiveness and Safety of Human Amnion/Chorion Membrane Therapy for Diabetic Foot Ulcers: An Updated Meta-analysis of Randomized Clinical Trials.

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Human amnion/chorion membrane therapy has shown advantages in the management of diabetic foot ulcers and its effectiveness has been evaluated in the systematic reviews and meta-analyses. However, the number of […]

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Optical imaging of collagen fiber damage to assess thermally injured human skin.

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Surgery is the definitive treatment for burn patients who sustain full thickness burn injuries. Visual assessment of burn depth is made by the clinician early after injury but is accurate […]

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The use of acellular porcine dermis, hyaluronic acid and polynucleotides in the treatment of cutaneous ulcers: Single blind randomised clinical trial.

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Reconstruction of chronic ulcers is often hampered by lack of local tissues and poor general conditions. Conservative approaches with debridement and advanced medications, such as polyurethane foam, stand as mainstays. […]

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Decreased Expression of miR-24 in Peripheral Plasma of Type 2 Diabetes Mellitus Patients Associated with Diabetic Foot Ulcer.

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To examine the correlations of miR-24 expression in peripheral plasma with the onset of diabetic foot ulcer (DFU) and diabetic foot osteomyelitis (DFO) in type 2 diabetes mellitus (T2DM) patients […]

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Fat graft for reducing pain in chronic wounds.

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Chronic wounds are one of the most important challenge for regenerative surgery. Plastic surgeon can use fat graft to increase wound healing because its growth factors can enhance tissue regeneration. […]

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Pathologic Scarring after Eyebrow Micropigmentation: A Case Report and Systematic Review.

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Skin tattooing and cosmetic eyebrow definition and reshaping (micropigmentation) have been growing exponentially in popularity. The pigment used in these procedures can activate the skin’s inflammatory response, promoting the formation […]

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The infected diabetic foot: Can serum biomarkers predict osteomyelitis after hospital discharge for diabetic foot infections?

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The aim of this study is to evaluate serum biomarkers to monitor high-risk patients for reinfection of bone. Thirty-five patients were prospectively enrolled with moderate to severe diabetic foot infections […]

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A pilot feasibility study of non-cultured autologous skin cell suspension for healing diabetic foot ulcers.

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A prospective, single arm feasibility study was conducted to evaluate healing outcomes of DFUs treated with autologous skin cell suspension (ASCS) in combination with standard therapy. Wounds up to 100 […]

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Evolution of ischemia and neovascularization in a murine model of full thickness human wound healing.

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Translation of wound healing research is limited by the lack of an appropriate animal model, due to the anatomic and wound healing differences in animals and humans. Here, we characterize […]

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Rapid Detection of Biofilm with Modified Alcian Blue Staining: In-vitro Protocol Improvement and Validation with Clinical Cases.

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For chronic wounds, biofilm infection is a critical issue because it can tip the scales toward an unhealing state. Biofilm-based wound therapy has been extensively advocated. However, point-of-care biofilm diagnosis […]

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