European Association of Urology (EAU) Prognostic Factor Risk Groups for Non-muscle-invasive Bladder Cancer (NMIBC) Incorporating the WHO 2004/2016 and WHO 1973 Classification Systems for Grade: An Update from the EAU NMIBC Guidelines Panel.

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The European Association of Urology (EAU) prognostic factor risk groups for non-muscle-invasive bladder cancer (NMIBC) are used to provide recommendations for patient treatment after transurethral resection of bladder tumor (TURBT). […]

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Value-Based Healthcare in Urology: A Collaborative Review.

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In response to growing concerns over rising costs and major variation in quality, improving value for patients has been proposed as a fundamentally new strategy for how healthcare should be […]

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Beyond Antimuscarinics: A Review of Pharmacological and Interventional Options for Overactive Bladder Management in Men.

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The role of overactive bladder (OAB) treatment in women beyond antimuscarinics has been evaluated extensively. Beta-3 agonists, botulinum toxin-A (BTX-A), and nerve stimulation are indicated in these patients. However, data […]

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Updated European Association of Urology Guidelines on Renal Cell Carcinoma: Nivolumab plus Cabozantinib Joins Immune Checkpoint Inhibition Combination Therapies for Treatment-naïve Metastatic Clear-Cell Renal Cell Carcinoma.

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Longer follow-up and new trial data from phase 3 randomised controlled trials investigating immune checkpoint blockade (PD-1 or its ligand PD-L1) in advanced clear-cell renal cell carcinoma (RCC) have recently […]

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A Randomized Controlled Trial of Pre-operative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy in Moderate to High Risk Infectious Risk Population: A Report from the EDGE Consortium.

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Post-operative infectious related complications are not uncommon after percutaneous nephrolithotomy. Previously, we noted that 7 days of antibiotics did not decrease sepsis rates compared to just peri-operative antibiotics in a […]

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Evaluation of the New American Urological Association Guidelines Risk Classification for Hematuria.

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Microhematuria is a prevalent condition and the American Urological Association (AUA) has developed a new risk-stratified approach for the evaluation of patients with microhematuria. Our objective was to provide the […]

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A Systematic Review of the Evidence for the Decipher Genomic Classifier in Prostate Cancer.

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Molecular biomarkers aim to address the established limitations of clinicopathologic factors to accurately risk stratify patients with prostate cancer (PCa). Questions remain as to whether sufficient evidence supports adoption of […]

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Antimicrobial Prophylaxis for Postoperative Urinary Tract Infections in Transurethral Resection of Bladder Tumors: A Systematic Review and Meta-analysis.

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The administration of antimicrobial prophylaxis (AMP) for postoperative urinary tract infections (UTIs) following transurethral resection of bladder tumors (TURB) is controversial. We aimed to systematically review evidence on the potential […]

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Qualitative Review of Clinical Guidelines for Medical and Surgical Management of Urolithiasis: Consensus and Controversy 2020.

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Many major guidelines across the globe address the medical and surgical management of urolithiasis. We elected to compare and contrast the recommendations among the five most highly-cited guidelines on stone […]

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Performance of Three Inherited Risk Measures for Predicting Prostate Cancer Incidence and Mortality: A Population-based Prospective Analysis.

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Single nucleotide polymorphism-based genetic risk score (GRS) has been developed and validated for prostate cancer (PCa) risk assessment. As GRS is population standardized, its value can be interpreted as a […]

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Prostate Cancer Screening Patterns Among Sexual and Gender Minority Individuals.

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One in six gay and bisexual men will be diagnosed with prostate cancer in their lifetime. Lesbian, gay, bisexual, and transgender (LGBT) populations are under-represented in cancer research, and guidelines […]

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Oncologic Outcomes after Localized Prostate Cancer Treatment: Associations with Pre-treatment Prostate MRI Findings.

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To investigate whether T2-weighted magnetic resonance imaging (MRI) findings could improve upon established prognostic indicators of metastatic disease and cancer-specific survival.For a cohort of 3,406 consecutive men who underwent prostate […]

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T1-Substaging of Non-muscle Invasive Bladder Cancer is Associated with BCG-Failure and Improves Patient Stratification at Diagnosis.

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Currently, markers are lacking that can identify high-risk non-muscle invasive bladder cancer (HR-NMIBC) patients who fail BCG-treatment. Therefore, we evaluated the prognostic value of T1-substaging in primary HR-NMIBC.Patients with primary […]

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EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.

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To present a summary of the 2020 version of the European Association of Urology (EAU)-European Association of Nuclear Medicine (EANM)-European Society for Radiotherapy and Oncology (ESTRO)-European Society of Urogenital Radiology […]

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Effect of Regional Citrate Anticoagulation vs Systemic Heparin Anticoagulation During Continuous Kidney Replacement Therapy on Dialysis Filter Life Span and Mortality Among Critically Ill Patients With Acute Kidney Injury: A Randomized Clinical Trial.

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Although current guidelines suggest the use of regional citrate anticoagulation (which involves the addition of a citrate solution to the blood before the filter of the extracorporeal dialysis circuit) as […]

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A Novel Dissection Gesture Classification to Characterize Robotic Dissection Technique for Renal Hilar Dissection.

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Deconstruction of robotic surgical gestures into semantic vocabulary yields an effective tool for surgical education. In this study we disassembled tissue dissection into basic gestures, created a classification system, and […]

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EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer. Part II-2020 Update: Treatment of Relapsing and Metastatic Prostate Cancer.

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To present a summary of the 2020 version of the European Association of Urology (EAU)-European Association of Nuclear Medicine (EANM)-European Society for Radiotherapy & Oncology (ESTRO)-European Society of Urogenital Radiology […]

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Ureteroscopy in Patients Taking Anticoagulant or Antiplatelet Therapy: Practice Patterns and Outcomes in a Surgical Collaborative.

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AUA guidelines recommend ureteroscopy (URS) as first-line therapy for patients on anticoagulant (AC) or antiplatelet (AP) therapy, and advocate using a ureteral access sheath (UAS). We examined practice patterns and […]

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Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART II.

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The summary presented herein represents Part II of the two-part series dedicated to Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline discussing prognostic and treatment recommendations for patients with castration-resistant disease. Please refer […]

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Imaging-based prostate cancer screening among BRCA mutation carriers-results from the first round of screening.

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Male-carriers of BRCA1/2 gene mutations have an increased risk of prostate cancer (PCa) with a more aggressive phenotype. Current screening-guidelines suggest the use of prostate-specific antigen (PSA) only among BRCA2 […]

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Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART I.

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The summary presented herein represents Part I of the two-part series dedicated to Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline discussing prognostic and treatment recommendations for patients with biochemical recurrence without metastatic […]

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A Systematic Review and Meta-Analysis of the Significance of Body Mass Index on Kidney Cancer Outcomes.

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Obesity is a well-known risk factor for kidney cancer incidence. However, a number of studies have demonstrated more favorable kidney cancer prognosis in patients with elevated body mass index (BMI) […]

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Association of Lower Urinary Tract Symptom Severity with Kidney Function Among Community-Dwelling Older Men.

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Most international practice guidelines recommend screening for chronic kidney disease among older men with lower urinary tract symptoms. However, prior studies supporting these guidelines are insufficient due to incomplete assessments […]

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Real World Practice Patterns Favor Minimally Invasive Methods over Ureteral Reconstruction in the Initial Treatment of Severe Blunt Ureteral Trauma – A National Trauma Data Bank Analysis.

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To utilize the National Trauma Data Bank® (NTDB) database to report practice patterns in managing blunt traumatic ureteral injuries (UIs) and assess its consistency with current guidelines/literature.Between 2007 and 2016, […]

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Infertile Men Have Higher Prostate-specific Antigen Values than Fertile Individuals of Comparable Age.

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Infertile men are at greater risk for oncological and nononcological chronic disease than fertile individuals.To investigate prostate-specific antigen (PSA) values in men presenting for primary couple’s infertility compared with a […]

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Discrepancy Between Post-vasectomy SA Recommendation and Practice Patterns in the Post 2012 AUA Guideline Era.

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In 2012, the American Urological Association published vasectomy guidelines to promote best practices including when to obtain post-vasectomy semen analyses (PVSA). We aimed to assess practice patterns of PVSA since […]

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