To assess sperm chromatin fragmentation (SCF) at different levels of the male genital tract.Ejaculated specimens from consenting male partners were screened for SCF by terminal deoxynucleotidyl dUTP nick-end labeling (TUNEL). […]» Read more
Urinary stone disease during pregnancy is poorly understood but is thought to be associated with increased maternal and fetal morbidity. We sought to determine the prevalence of urinary stone disease […]» Read more
Efficacy, safety, and tolerability of mirabegron in patients aged ≥65yr with overactive bladder wet: a phase IV, double-blind, randomised, placebo-controlled study (PILLAR).
The majority of patients with overactive bladder (OAB) are aged >65yr. There has been no prospectively designed study assessing treatment efficacy with the β3-adrenoreceptor agonist, mirabegron, specifically in this age […]» Read more
In the randomized, open-label, phase 3 CheckMate 214 trial, nivolumab plus ipilimumab (nivolumab 3 mg/kg plus ipilimumab 1 mg/kg every 3 wk for four doses, then nivolumab 3 mg/kg every 2 wk) had […]» Read more
Wnt-pathway Activating Mutations Are Associated with Resistance to First-line Abiraterone and Enzalutamide in Castration-resistant Prostate Cancer.
Abstract empty Click here to read the full article @ European Urology» Read more
Urinary incontinence (UI) and fecal incontinence (FI) are common disorders in women that negatively impact quality of life. In addition to known health and lifestyle risk factors, genetics may play […]» Read more
Click here to read the full article @ European Urology» Read more
Re: Analysis of the Completely Dry Rate over Time after Mid-Urethral Sling in a Real-World Clinical Setting.
Re: Estimated Minimal Residual Membranous Urethral Length on Preoperative Magnetic Resonance Imaging Can be a New Predictor for Continence after Radical Prostatectomy.
Re: A Culture-Independent Analysis of the Microbiota of Female Interstitial Cystitis/Bladder Pain Syndrome Participants in the MAPP Research Network.
Local Failure and Survival After Definitive Radiotherapy for Aggressive Prostate Cancer: An Individual Patient-level Meta-analysis of Six Randomized Trials.
The importance of local failure (LF) after treatment of high-grade prostate cancer (PCa) with definitive radiotherapy (RT) remains unknown.To evaluate the clinical implications of LF after definitive RT.Individual patient data […]» Read more
Development and External Validation of a mpMRI- and ISUP-Based Add-on Prediction Tool to Identity Prostate Cancer Candidates for Pelvic Lymph Node Dissection.
To expand the current prediction tools for lymph node invasion (LNI) in prostate cancer (PCa) patients with today’s state-of-the-art available tumor information, including multiparametric MRI (mpMRI)-based tumor (T) staging and […]» Read more
Effect of Bempedoic Acid vs Placebo Added to Maximally Tolerated Statins on Low-Density Lipoprotein Cholesterol in Patients at High Risk for Cardiovascular Disease: The CLEAR Wisdom Randomized Clinical Trial.
Additional treatment options are needed for patients who do not achieve sufficient reduction in low-density lipoprotein cholesterol (LDL-C) level with available lipid-lowering therapies.To assess the efficacy of bempedoic acid vs […]» Read more