Improvement of Storage-Related Lower Urinary Tract Symptoms Following Urethroplasty: A Prospective Cohort Study.

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In patients with lower urinary tract symptoms (LUTS) storage-related symptoms induce the greatest degree of bother. When associated with urethral stricture, it’s unclear how these specific symptoms respond to urethroplasty. […]

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Antireflux Surgery at National Surgical Quality Improvement Program-Pediatric Hospitals.

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This study aims to examine contemporary practice patterns and compare short-term outcomes for vesicoureteral reflux procedures (ureteral reimplant/endoscopic injection) using National Surgical Quality Improvement Program-Pediatric data.Procedure-specific variables for antireflux surgery […]

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PSMA PET/CT in the Evaluation of Initial Response in Candidates Who Underwent Salvage Radiation Therapy after Radical Prostatectomy for Prostate Cancer.

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To assess predictors for the short-term oncological outcome of patients who underwent salvage radiation therapy (SRT) for biochemical recurrence (BCR) after robot-assisted laparoscopic radical prostatectomy (RARP), without evidence of metastases […]

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A Comparison of Prostate Cancer Detection Between Visual-Estimation (Cognitive Registration) and Image-Fusion (Software Registration) Targeted Transperineal Prostate Biopsy.

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To compare clinically significant prostate cancer (csPCa) detection by visual-estimation and image-fusion targeted transperineal prostate biopsy.This multi-centre study included patients with multiparametric MRI (mpMRI) lesions undergoing visual-estimation or image-fusion targeted […]

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Diagnostic Test Characteristics of Ultrasound-Based Hydronephrosis in Identifying Low Kidney Function in Young Patients with Spina Bifida: A Retrospective Cohort Study.

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Kidney dysfunction in spina bifida (SB) is usually detected by low estimated glomerular filtration rate (eGFR) or ultrasound-based hydronephrosis. We assessed the diagnostic test characteristics of hydronephrosis for detecting low […]

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Oncologic Outcomes after Localized Prostate Cancer Treatment: Associations with Pre-treatment Prostate MRI Findings.

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To investigate whether T2-weighted magnetic resonance imaging (MRI) findings could improve upon established prognostic indicators of metastatic disease and cancer-specific survival.For a cohort of 3,406 consecutive men who underwent prostate […]

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A DROP-IN Gamma Probe for Robot-assisted Radioguided Surgery of Lymph Nodes During Radical Prostatectomy.

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The DROP-IN gamma probe was introduced to overcome the restricted manoeuvrability of traditional laparoscopic gamma probes. Through enhanced manoeuvrability and surgical autonomy, the DROP-IN promotes the implementation of radioguided surgery […]

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Initial Experience with Intracorporeal Laparoscopic Radical Cystectomy and Detaenial Sigmoid Neobladder Reconstruction.

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Intracorporeal urinary diversion is considered to be effective in improving intestinal function recovery and reducing the occurrence of early complications after radical cystectomy. Almost all neobladders constructed via intracorporeal laparoscopy […]

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Persistence and Adherence of Anticholinergics and Beta-3 Agonist for the Treatment of Overactive Bladder: Systematic Review and Meta-Analysis, and Network Meta-Analysis.

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To investigate the persistence and adherence rate of overactive bladder medications and factors that affect these rates.Electronic English-language literature searches of the PubMed, Cochrane Library, and EMBASE databases from the […]

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Can 68Ga-PSMA-11 PET/CT Predict Pathologic Response of Primary Prostate Cancer to Neoadjuvant Androgen Deprivation Therapy: A Pilot Study.

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To explore the role of 68Ga-PSMA-11 PET/CT as a predictor of pathologic response to neoadjuvant androgen deprivation therapy (ADT) combined with abiraterone for high-risk prostate cancer (PCa).Forty-five patients with localized […]

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The Clinical Significance of Multiple Negative Surveillance Prostate Biopsies for Men on Active Surveillance-Does Cancer Vanish or Simply Hide?

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Men with low risk prostate cancer on active surveillance undergo multiple biopsies over time. The long-term clinical significance of consecutively negative biopsies is not known.Men with low risk prostate cancer […]

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T1-Substaging of Non-muscle Invasive Bladder Cancer is Associated with BCG-Failure and Improves Patient Stratification at Diagnosis.

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Currently, markers are lacking that can identify high-risk non-muscle invasive bladder cancer (HR-NMIBC) patients who fail BCG-treatment. Therefore, we evaluated the prognostic value of T1-substaging in primary HR-NMIBC.Patients with primary […]

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Surgical Management of Retrocrural Disease in Germ Cell Tumors: Outcomes and Evolution of Practice.

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Residual retrocrural disease in testis cancer following chemotherapy is a surgical challenge. We sought to assess the outcomes and evolution with surgical management of residual retrocrural disease.We identified 2,788 testicular […]

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The Predictive Value of Programmed Death Ligand 1 in Patients with Metastatic Renal Cell Carcinoma Treated with Immune-checkpoint Inhibitors: A Systematic Review and Meta-analysis.

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Immune-checkpoint inhibitors (ICIs) are a mainstay treatment of metastatic renal cell carcinoma (mRCC). As not all patients benefit from ICIs, a biomarker-driven clinical decision-making strategy is desirable.To assess the predictive […]

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EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.

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To present a summary of the 2020 version of the European Association of Urology (EAU)-European Association of Nuclear Medicine (EANM)-European Society for Radiotherapy and Oncology (ESTRO)-European Society of Urogenital Radiology […]

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Integrated Expression of Circulating miR375 and miR371 to Identify Teratoma and Active Germ Cell Malignancy Components in Malignant Germ Cell Tumors.

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Active germ cell malignancies express high levels of specific circulating micro-RNAs (miRNAs), including miR-371a-3p (miR371), which is undetectable in teratoma. Teratoma markers are urgently needed for theselection of patients and […]

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Taxane-induced Attenuation of the CXCR2/BCL-2 Axis Sensitizes Prostate Cancer to Platinum-based Treatment.

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Taxanes are the most active chemotherapy agents in metastatic castration-resistant prostate cancer (mCRPC) patients; yet, resistance occurs almost invariably, representing an important clinical challenge. Taxane-platinum combinations have shown clinical benefit […]

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