Surgical Management and Outcomes of Renal Tumors Arising from Horseshoe Kidneys: Results from an International Multicenter Collaboration.

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Despite being the most frequent renal fusion anomaly, tumors arising from horseshoe kidneys (HSKs) are extremely rare and management guidance is lacking.To evaluate the perioperative, oncological, and functional outcomes of […]

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Hybrid Indocyanine Green-99mTc-nanocolloid for Single-photon Emission Computed Tomography and Combined Radio- and Fluorescence-guided Sentinel Node Biopsy in Penile Cancer: Results of 740 Inguinal Basins Assessed at a Single Institution.

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Sentinel node (SN) biopsy in penile cancer (PeCa) is typically performed using 99mTc-nanocolloid and blue dye. Recent reports suggested that the hybrid (radioactive and fluorescent) tracer indocyanine green (ICG)-99mTc-nanocolloid may […]

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Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer.

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We previously reported that olaparib led to significantly longer imaging-based progression-free survival than the physician’s choice of enzalutamide or abiraterone among men with metastatic castration-resistant prostate cancer who had qualifying […]

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Technical Refinements in Superextended Robot-assisted Radical Prostatectomy for Locally Advanced Prostate Cancer Patients at Multiparametric Magnetic Resonance Imaging.

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The feasibility and efficacy of robot-assisted radical prostatectomy (RARP) in locally advanced prostate cancer (PCa) patients with iT3 lesion at magnetic resonance imaging (MRI) are currently not explored.To describe our […]

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A Systematic Review and Meta-Analysis of the Significance of Body Mass Index on Kidney Cancer Outcomes.

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Obesity is a well-known risk factor for kidney cancer incidence. However, a number of studies have demonstrated more favorable kidney cancer prognosis in patients with elevated body mass index (BMI) […]

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Rates and Patterns of Recurrences, and Survival Outcomes after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium.

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There have been concerns about higher incidence of local and retroperitoneal recurrences after robot-assisted radical cystectomy (RARC) compared to open radical cystectomy. We sought to report and detail relapses following […]

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Efficacy of Daily Intake of Dried Cranberry 500 mg in Women with Overactive Bladder: A Randomized, Double-Blind, Placebo-Controlled Study.

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To determine the efficacy of dried cranberry on reducing symptoms of overactive bladder in women.Eligible women aged 18 or older with overactive bladder were randomized to either daily dried cranberry […]

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A Urine Exosome Gene Expression Panel Distinguishes Between Indolent and Aggressive Prostate Cancers at Biopsy.

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Prostate cancer is predominantly indolent at diagnosis with a small fraction (15-25%) representing aggressive subtype [Gleason score (GS) 7-10], which is prone to metastatic progression. It is critical to explore […]

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Final Overall Survival Results from a Phase 3 Study to Compare Tivozanib to Sorafenib as Third- or Fourth-line Therapy in Subjects with Metastatic Renal Cell Carcinoma.

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Tivozanib is a potent and selective inhibitor of the VEGF receptor. In an open-label, randomized phase 3 trial, we compared tivozanib to sorafenib in patients with metastatic renal cell carcinoma […]

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Detection Rate of Prostate-Specific Membrane Antigen Tracers for Positron Emission Tomography/Computed Tomography in Prostate Cancer Biochemical Recurrence: A Systematic Review and Network Meta-Analysis.

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Restaging of prostate cancer in patients with biochemical recurrence (BCR) after radical treatment remains a challenging clinical scenario as current imaging modalities are suboptimal. To date, PSMA PET/CT seems to […]

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Robotic Kidney Transplantation with Regional Hypothermia Versus Open Kidney Transplantation for Patients with End-Stage Renal Disease: An Ideal Stage 2B Study.

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To report on comparative effectiveness of minimally invasive versus traditional open kidney transplantation.We undertook a prospective cohort study of 654 patients who underwent open or robotic kidney transplantation at a […]

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Erectile Dysfunction in a Sample of Sexually Active Young Adult Men from a US Cohort: Demographic, Metabolic, and Mental Health Correlates.

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Little is understood about physiologic and psychologic correlates of erectile dysfunction (ED) among younger men. This study examined prevalence and correlates of ED in a large US sample of 18-31 […]

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Sequencing of PD-1/L1 Inhibitors and Carboplatin-Based Chemotherapy for Cisplatin-Ineligible Metastatic Urothelial Carcinoma.

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Current first-line treatment options in patients with metastatic urothelial carcinoma (mUC) unfit to receive cisplatin-containing chemotherapy include PD-1/L1 inhibitors and carboplatin-containing chemotherapy. However, the optimal sequencing of these therapies remains […]

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psychological intervention with parents improves treatment results and reduces punishment in enuretic children: a randamized clinical trial.

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This study aims to evaluate the impact of psychological intervention with parents of enuretic children on treatment outcome.Sixty-six enuretic children were randomized into two groups. All children received urotherapy orientation […]

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Association of Lower Urinary Tract Symptom Severity with Kidney Function Among Community-Dwelling Older Men.

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Most international practice guidelines recommend screening for chronic kidney disease among older men with lower urinary tract symptoms. However, prior studies supporting these guidelines are insufficient due to incomplete assessments […]

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Regimented Phosphodiesterase Type 5 Inhibitor Use Reduces Emergency Department Visits for Recurrent Ischemic Priapism.

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To evaluate the real-world effectiveness of regimented phosphodiesterase type 5 inhibitor (regPDE5i) dosing on recurrent ischemic priapism (RIP) outcomes, using emergency department (ED) visits as a proxy for therapeutic control […]

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Comparative Effectiveness of Surveillance, Primary Chemotherapy, Radiotherapy, and Retroperitoneal Lymph Node Dissection for the Management of Early-Stage Testicular Germ Cell Tumors: A Systematic Review.

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Cancer-specific survival for men with early-stage (Stage I-IIB) testicular germ cell tumors (TGCT) is greater than 90% with any management strategy. The data regarding the comparative effectiveness of surveillance, primary […]

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Racial differences in urinary incontinence prevalence, overactive bladder and associated bother among men: The Multi-Ethnic Study of Atherosclerosis.

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To examine the association of race/ethnicity with urinary incontinence subtypes and overactive bladder and associated bother in older men.This cross-sectional analysis utilized data from Multi-Ethnic Study of Atherosclerosis, an observational […]

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Patient-Reported vs. Claims-Based Measures of Health for Modeling Life Expectancy in Men with Prostate Cancer.

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Life expectancy has become a core consideration in prostate cancer care. While multiple prediction tools exist to support decision-making, their discriminative ability remains modest, which hamper usage and utility. We […]

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Nonmetastatic, Castration-Resistant Prostate Cancer and Survival with Darolutamide.

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Darolutamide is a structurally distinct androgen-receptor inhibitor that is approved for the treatment of nonmetastatic, castration-resistant prostate cancer. In the planned primary analysis of a phase 3 trial, the median […]

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Mid Urethral Slings for the Treatment of Urodynamic Stress Incontinence in Overweight and Obese Women: Surgical Outcomes and Preoperative Predictors of Failure.

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We evaluated mid urethral sling outcomes in overweight and obese patients compared to normal weight patients and identified risk factors for failure in this population.Records of 688 women between January […]

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High Intensity Focused Ultrasound Hemigland Ablation for Prostate Cancer: Initial Outcomes of a United States Series.

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We report outcomes of hemigland high intensity focused ultrasound ablation as primary treatment for localized prostate cancer in the United States.A total of 100 consecutive men underwent hemigland high intensity […]

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