Mutiparametric Magnetic Resonance Imaging Alone is Insufficient to Detect Grade Reclassification in Active Surveillance for Prostate Cancer.

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Multiparametric magnetic resonance imaging (mpMRI) has improved the detection of clinically significant prostate cancer. It remains unclear, however, whether mpMRI can safely replace confirmatory or surveillance biopsies in men with […]

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Assessing the Best Surgical Template at Salvage Pelvic Lymph Node Dissection for Nodal Recurrence of Prostate Cancer After Radical Prostatectomy: When Can Bilateral Dissection be Omitted? Results from a Multi-institutional Series.

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The best surgical template for salvage pelvic lymph node dissection (sLND) in patients with nodal recurrence from prostate cancer (PCa) after radical prostatectomy (RP) is currently unknown. We analyzed data […]

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High-Density Surface Electromyography Assessment of Pelvic Floor Dysfunction in Women with Interstitial Cystitis/Bladder Pain Syndrome.

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Up to 85% of women with interstitial cystitis/bladder pain syndrome (IC/BPS) have pelvic floor dysfunction and hypertonicity. Current evaluation methodologies lack objective measures of pelvic floor muscle (PFM) activity. We […]

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A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts.

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Cyclic high-dose testosterone injections, also known as bipolar androgen therapy (BAT), is a novel treatment strategy for patients with metastatic castration-resistant prostate cancer (mCRPC). BAT has shown clinical activity in […]

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Reporting Radical Cystectomy Outcomes Following Implementation of Enhanced Recovery After Surgery Protocols: A Systematic Review and Individual Patient Data Meta-analysis.

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Enhanced Recovery After Surgery (ERAS) is a perioperative approach to managing surgical patients. The impact of ERAS on radical cystectomy (RC) outcomes remains understudied.To review the literature regarding ERAS protocols […]

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Long-term Outcomes of Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer After Radical Prostatectomy: Not as Good as Previously Thought.

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Long-term outcomes of patients treated with salvage lymph node dissection (sLND) for nodal recurrence of prostate cancer (PCa) remain unknown.To investigate long-term oncological outcomes after sLND in a large multi-institutional […]

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Development of a Novel Scoring System Quantifies Opportunities to Reduce Surgery for Benign Renal Neoplasms: A Retrospective Quality Improvement Analysis within the MUSIC KIDNEY Collaborative.

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Non-malignant pathology (NMP) has been reported in 15-20% of surgeries for cT1 renal masses (cT1RM). We seek to identify opportunities for improvement in avoiding surgery for NMP.MUSIC-KIDNEY started collecting data […]

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Pain in Men Undergoing Transperineal Free-Hand mpMRI Fusion-Targeted Biopsies under Local Anesthesia: Outcomes and Predictors from a Multicenter Study of 1,008 Patients.

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Several TP biopsy series proved feasibility under LA. However, there is a lack of large analysis detailing pain outcomes and factors influencing pain.From 2016 to 2019 we performed a multicenter […]

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Diagnostic Assessment of Lower Urinary Tract Symptoms in Men Considering Prostate Surgery: A Noninferiority Randomised Controlled Trial of Urodynamics in 26 Hospitals.

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Prostate surgery can improve lower urinary tract symptoms (LUTS) by relieving bladder outlet obstruction (BOO). However, surgery is less effective without BOO, or if detrusor underactivity is present. Urodynamics (UDS) […]

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Competency in TIP Repair for Distal Hypospadias: Cumulative Sum Learning Curve Analysis of a Single Surgeon Experience.

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To determine the number of cases to achieve competency and proficiency in tubularized incised plate (TIP) technique for distal hypospadias repair using cumulative sum analysis (CUSUM).From 2001-2015, We reviewed all […]

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Differential Impact of Gonadotropin-releasing Hormone Antagonist Versus Agonist on Clinical Safety and Oncologic Outcomes on Patients with Metastatic Prostate Cancer: A Meta-analysis of Randomized Controlled Trials.

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Androgen deprivation therapy is the mainstay treatment of metastatic prostate cancer, achieved mainly by gonadotropin-releasing hormone (GnRH) agonists or antagonists.To investigate the differential impact of GnRH agonists and antagonists on […]

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Microorganisms and Antibiogram Patterns in Fournier’s Gangrene: Contemporary Experience from a Single Tertiary Care Center.

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To evaluate the prevalent microorganisms, antibiotic sensitivity patterns, and associated outcomes in patients with Fournier’s Gangrene (FG).A retrospective chart review of patients with FG was conducted between October 2011 and […]

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Intra-prostatic Cancer Recurrence following Radical Radiotherapy on Transperineal Template Mapping Biopsy: Implications for Focal Ablative Salvage Therapy.

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Men who fail external beam radiotherapy (EBRT) are usually placed on delayed hormone therapy. Some of these men have localised recurrence that might be suitable for further local therapy. We […]

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Modified Apical Dissection and Lateral Prostatic Fascia Preservation Improves Early Postoperative Functional Recovery in Robotic-assisted Laparoscopic Radical Prostatectomy: Results from a Propensity Score-matched Analysis.

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Early recovery of continence and potency after robotic-assisted laparoscopic prostatectomy (RALP) still remains a challenge.To assess the effect of our modified apical dissection and lateral prostatic fascia preservation (mod-RALP) technique […]

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