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To estimate absolute and relative risks for all-cause mortality and for severe COVID-19 in inflammatory joint diseases (IJDs) and with antirheumatic therapies.Through Swedish nationwide multiregister linkages, we selected all adult […]
» Read moreMonogenic autoinflammatory diseases (AID) are caused by mutations in innate immune genes. The effects of these mutations on allergic inflammation are unknown.We investigated allergic, immunological and clinical phenotypes in FMF […]
» Read moreIn this study, we explored the effect of semaphorin5A (SEMA5A) on rheumatoid arthritis (RA) pathogenesis and its specific TSP1 domain on pannus formation.The expression of SEMA5A was detected in synovium, […]
» Read moreAnimal models for inflammatory arthritides such as rheumatoid arthritis (RA) and psoriatic arthritis are widely accepted and frequently used to identify pathological mechanisms and validate novel therapeutic strategies. Unfortunately, many […]
» Read moreTo describe how many people with rheumatoid arthritis (RA) reduce their baseline physical activity (PA) level over the first year of methotrexate (MTX) treatment, and which factors predict this.Data came […]
» Read moreCartilage and bone damage in rheumatoid arthritis (RA) are associated with elevated IL-1β. The effects of IL-1β can be reduced by biological therapies that target IL-1β or TNFα. However, the […]
» Read moreTo evaluate the proportion of patients with ERA who have initiated or not GC, to analyse the baseline characteristics, and to assess the clinical benefit and side effects of GC […]
» Read moreTo identify clinical factors associated with cancer risk in the idiopathic inflammatory myopathies (IIMs) and to systematically review the existing evidence related to cancer screening.A systematic literature search was carried […]
» Read moreColour-doppler ultrasonography is the first measure to allow objective bedside assessment of Giant Cell Arteritis (GCA). This paper discusses the evidence using the OMERACT filter. Consensus definitions for ultrasonography changes […]
» Read moreAt the 2020 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)- Collaborative Research Network (CRN) annual meeting, the GRAPPA-CRN group presented a pilot investigator-initiated study protocol to […]
» Read moreTo examine demographic and clinical characteristics associated with diagnostic delay in psoriatic arthritis (PsA).We characterized a retrospective, population-based cohort of incident adult (≥18 years) PsA patients from Olmsted County, MN […]
» Read moreThe Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) held its annual meeting in 2020 in an online format due to travel restrictions during the coronavirus disease […]
» Read moreMacrophage activation syndrome (MAS) constitutes one subtype of the hyperinflammatory syndrome hemophagocytic lymphohistiocytosis (HLH), and the term MAS-HLH was recently proposed for HLH with underlying autoimmune/autoinflammatory conditions. The mortality of […]
» Read moreThis study aimed to describe pulmonary high-resolution computed tomography (HRCT) findings in Takayasu arteritis (TA) and to determine possible causes.A total of 243 TA patients were enrolled from a prospective […]
» Read moreThigh muscle weakness is associated with knee discomfort and osteoarthritis disease progression. Little is known about the efficacy of high-intensity strength training in patients with knee osteoarthritis or whether it […]
» Read moreEvaluation of a psoriatic arthritis (PsA), multidimensional, patient completed disease flare questionnaire (FLARE).The FLARE questionnaire was administered to 139 patients in a prospective observational study. The ‘gold standard’ of flare […]
» Read moreOn March 11, 2020, the World Health Organization (WHO) declared COVID-19 a pandemic. By mid-March, all Canadian provinces and territories declared states of emergency which triggered measures to support the […]
» Read moreTo assess the association between familial Mediterranean fever and asthma.This study was designed as a cross-sectional study. All patients diagnosed with familial Mediterranean fever between January 1, 2000, to December […]
» Read moreTocilizumab (TCZ), an IL-6 receptor antagonist, is approved for giant cell arteritis (GCA) as a cortisone-sparing strategy and in refractory patients. This study assessed the real-world efficacy, safety, and long-term […]
» Read moreA summary of the research conducted by the recipients of the 2019 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) Research Awards is presented. Dr. Alla Ishchenko’s […]
» Read moreThe biomarkers of an immunological dysregulation due to a chronic Hepatitis B virus (HBV) infection are indeed understudied. If untreated, this condition may evolve into liver impairment also co-occurred by […]
» Read moreIn response to the travel restrictions due to the COVID-19 (coronavirus disease 2019; caused by SARS-CoV-2) pandemic and recognizing that virtual meetings and symposia may play an important role in […]
» Read moreIncreasing numbers of patients are developing rheumatoid arthritis (RA) at an older age, and optimal treatment of elderly-onset RA (EORA) patients is attracting greater attention. This study aimed to analyze […]
» Read moreThroughout 2020, the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) has been working to update the GRAPPA treatment recommendations for psoriasis and psoriatic arthritis (PsA). The […]
» Read moreWe sought to clarify the presence of radiographic thymus variants using a scoring system, and their association with clinical and immunological features in RA patients.387 RA patients randomly selected from […]
» Read moreInterleukin 11 (IL11) is highly upregulated in skin and lung fibroblasts from patients with systemic sclerosis (SSc). Here we tested whether IL11 is mechanistically linked with activation of human dermal […]
» Read moreTo compare the incident risk of rheumatoid arthritis (RA) in patients with type 2 diabetes mellitus (T2DM), and to explore the role of glycaemic control and associated therapeutic use on […]
» Read moreTo summarise the available information on efficacy and safety of immunomodulatory agents in SARS-CoV-2 infection.As part of a European League Against Rheumatism (EULAR) taskforce, a systematic literature search was conducted […]
» Read moreTo evaluate the impact of upadacitinib vs placebo and adalimumab treatment, on patient-reported outcomes (PROs) in SELECT-COMPARE in an active RA population with inadequate responses to methotrexate (MTX-IR).PROs in patients […]
» Read moreTo assess trends in incidence of cardiovascular disease (CVD) and mortality following incident CVD events in patients with rheumatoid arthritis (RA) onset in 1980- 2009 versus non-RA subjects.We studied Olmsted […]
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