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To estimate the overall risk of venous thromboembolism (VTE), pulmonary embolism (PE) and deep vein thrombosis (DVT) among patients newly diagnosed with RA compared with the general population without RA; […]
» Read moreAnkylosing spondylitis (AS) is associated with an elevated risk of cardiovascular disease (CVD) related to atherosclerosis, preceded by arterial stiffness. We aimed to examine common carotid artery (CCA) biomechanical properties […]
» Read moreCardiovascular (CV) morbidity and mortality are increased in axial spondyloarthritis (axSpA). We conducted a cross-sectional study evaluating the 10-year atherosclerotic cardiovascular disease (ASCVD) risk in axSpA compared to the general […]
» Read moreCognitive dysfunction (CD) is a poorly understood non-stroke central neurological manifestation in anti-phospholipid syndrome (APS). Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays an important role in neural plasticity […]
» Read moreObservational studies allow researchers to understand the natural history of rheumatic conditions, risk factors for disease development, factors affecting important disease-related outcomes and estimate treatment effect from real world data. […]
» Read moreResearch findings in gout result predominantly from studies among men, and might not be generalizable to women. To improve insight into sex differences, this study compared clinical characteristics and comorbidities […]
» Read moreTo analyse the clinical features and prognostic factors of microscopic polyangiitis (MPA) with diffuse alveolar haemorrhage (DAH).We conducted a retrospective study of 92 patients diagnosed with MPA with DAH at […]
» Read moreTo evaluate the feasibility and preliminary effectiveness of iCanCope with Pain (iCanCope), a smartphone-based pain self-management program, in adolescents with JIA. iCanCope featured symptom tracking, goal-setting, pain coping skills and […]
» Read moreTo examine the effects of laser moxibustion on pain and function in patients with knee osteoarthritis.A double-blind randomized clinical trial (4-week treatment, 20-week follow-up) was conducted. A total of 392 […]
» Read moreTo identify rheumatologists’ views on perceived barriers and facilitators to the clinical implementation of patient-reported outcome measures (PROMs).Semi-structured interviews were conducted with academically affiliated clinical rheumatologists. Interviews were audio-recorded and […]
» Read moreTo quantify health care utilization and costs by disease severity for patients with systemic lupus erythematosus (SLE) in the United States METHODS: We conducted descriptive analyses of Humedica electronic health […]
» Read moreTo explore whether trial population characteristics modify treatment responses across various interventions, comparators and rheumatic conditions.In this meta-epidemiological study, we included trials from systematic reviews available from the Cochrane Musculoskeletal […]
» Read moreTo prospectively investigate whether differences in pulmonary vasculature exist in systemic sclerosis (SSc) and how they are distributed in patients with different pulmonary function.Seventy-four patients with SSc undergoing chest CT […]
» Read moreEvidence on comorbidity prevalence in antiphospholipid syndrome (APS) and its difference from high comorbidity burden rheumatic diseases is limited. Herein, we compare multiple comorbidities between APS and RA.A total of […]
» Read moreMTX remains the cornerstone for therapy for RA, yet research shows that non-adherence is significant and correlates with response to therapy. This study aimed to halve self-reported non-adherence to MTX […]
» Read morePatients with RA are frequently treated with glucocorticoids (GCs), but evidence is conflicting about whether GCs are associated with hypertension. The aim of this study was to determine whether GCs […]
» Read moreTo identify dysregulated microRNAs (miRNAs) and their gene targets in temporal arteries from GCA patients, and determine their association with GCA pathogenesis and related arterial wall remodelling.We included 93 formalin-fixed, […]
» Read moreRA is an autoimmune inflammatory joint disease. Both RF and ACPA are associated with more progressive disease and higher levels of systemic inflammation. Monocyte activation of toll-like receptors (TLRs) by […]
» Read moreTo analyse the influence of the Mediterranean diet (Med Diet) on SLE activity, damage accrual and cardiovascular disease risk markers.A cross-sectional study was conducted on 280 patients with SLE [46.9 (12.85) years]. […]
» Read moreTo assess whether the presence of arthritis autoantibodies alongside IgG ACPA predicts clinically suspect arthralgia in ACPA-positive subjects without RA.In the population-based Lifelines cohort (n = 40 136), 308 IgG ACPA-positive individuals without […]
» Read moreTo examine trends in the initial prescription of commonly-prescribed analgesics and patient- as well as practice-level factors related to their selection in incident OA.Patients consulting with incident clinical OA between […]
» Read moreFour clinical phenotypes of IgG4-related disease (IgG4-RD) have been recently identified by latent class analysis (LCA): pancreato-biliary (group 1); retroperitoneum/aortitis (group 2); head and neck limited (group 3); and Mikulicz/systemic […]
» Read moreTo assess secular trends in baseline characteristics of PsA patients initiating their first or subsequent biologic DMARD (bDMARD) therapy and to explore prescription patterns and treatment rates of bDMARDs from […]
» Read moreTo compare effectiveness of treatment with secukinumab (SEC) with that of alternative tumour necrosis factor inhibitors (TNFis) in patients with axial spondyloarthritis (axSpA) after withdrawal from one or more TNFis.Patients diagnosed […]
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