Low prognostic value of novel nocturnal oxygen saturation metrics in patients with obstructive sleep apnea and high cardiovascular event risk: post-hoc analyses of the SAVE study.

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Traditional methods for quantifying obstructive sleep apnea (OSA) severity may not encapsulate potential relationships between hypoxaemia in OSA and cardiovascular (CV) risk.Do novel nocturnal oxygen saturation metrics have prognostic value […]

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Impact of a multimodal telemonitoring intervention on CPAP adherence in symptomatic low-cardiovascular risk sleep apnea: a randomized controlled trial.

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One of the major challenges in treating obstructive sleep apnea (OSA) is to achieve adequate continuous positive airway pressure (CPAP) adherence. Telemonitoring has the potential to provide individualized management and […]

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Association between nocturnal hypoxemia and cancer incidence in patients investigated for obstructive sleep apnea. Data from a large multicenter French cohort.

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Previous studies have yielded inconsistent findings regarding the association between obstructive sleep apnea (OSA) and cancer in humans.Is there an association between indices of sleep-disordered breathing severity and cancer incidence […]

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Nonoperating room anesthesia for patients with serious comorbidities.

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To provide aids to deal with increasing amount of several comorbidities in nonoperating room anesthesia (NORA).New indexes for assessment of comorbidities are described and guidelines for the care of patients […]

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Air pollution and systemic inflammation in patients with suspected obstructive sleep apnea living in an urban residential area.

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Air pollution and obstructive sleep apnea (OSA) are independently associated with systemic inflammation, but it is unknown if these exposures interact to influence systemic inflammation.Our objective was to determine the […]

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Continuous Positive Airway Pressure Treatment, Glycemia, and Diabetes Risk in Obstructive Sleep Apnea and Comorbid Cardiovascular Disease.

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Despite evidence of a relationship among obstructive sleep apnea (OSA), metabolic dysregulation, and diabetes, it is uncertain whether OSA treatment can improve metabolic parameters. We sought to determine effects of […]

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Efficacy of continuous positive airway pressure (CPAP) for improvements in sleepiness, cognition, mood and quality of life in elderly patients with obstructive sleep apnea: Systematic review and meta-analysis of randomized controlled trials.

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Obstructive sleep apnea (OSA) is commonly found in the elderly population (≥ 65 years old), and continuous positive airway pressure (CPAP) improves sleepiness, health-related quality of life (HRQoL) in the […]

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The Effect of Venlafaxine on Apnea Hypopnea Index in Patients with Sleep Apnea – a Randomized, Double-Blind Crossover Study.

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One of the key mechanisms underlying obstructive sleep apnea (OSA) is a reduced pharyngeal muscle tone during sleep. Recent data suggest that pharmacological augmentation of central serotonergic/adrenergic tone increases pharyngeal […]

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Relation of Age to Survival in Patients with Obstructive Sleep Apnea who Develop an Acute Coronary Event (from the National Inpatient Sample).

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This study was undertaken to investigate whether obstructive sleep apnea (OSA) produces a survival advantage in acute coronary syndrome (ACS), and to evaluate the mechanism of any benefit, including the […]

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Obstructive sleep apnoea treatment and blood pressure: which phenotypes predict a response? A systematic review and meta-analysis.

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The treatment for obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) or mandibular advancement devices (MAD) is associated with blood pressure (BP) reduction however, the overall effect is […]

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Palatal Sensory Function Worsens in Untreated Snorers but not in CPAP-treated Sleep Apnea Patients, indicating Vibration-induced Nervous Lesions.

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snoring per se may damage all upper airway neurons over time, thereby causing progression to manifest sleep apnea. To test this, non-snoring subjects, untreated snorers and CPAP-treated patients underwent repeated […]

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