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The interaction between tumor size and the comparative prognosis of lobar and sublobar resection has been poorly defined.The purpose of this study was to characterize the relationship between tumor size […]
» Read moreGenetic factors influence chronic obstructive pulmonary disease (COPD) risk, but the individual variants that have been identified have small effects. We hypothesised that a polygenic risk score using additional variants […]
» Read moreLung cancer screening with low-dose chest CT (LDCT) reduces the mortality of eligible individuals. Blood signatures might act as a standalone screening tool, refine the selection of patients at risk, […]
» Read moreMethotrexate (MTX) is a key anchor drug for rheumatoid arthritis (RA) management. Fibrotic interstitial lung disease (ILD) is a common complication of RA. Whether MTX exposure increases the risk of […]
» Read moreThe term interstitial lung abnormalities refers to specific CT findings that are potentially compatible with interstitial lung disease in patients without clinical suspicion of the disease. Interstitial lung abnormalities are […]
» Read moreAn increased incidence of lung cancer is well-known among patients with idiopathic pulmonary fibrosis. It is unknown whether interstitial lung abnormalities, early fibrotic changes of the lung, are a risk […]
» Read moreThe COVID-19 pandemic has seen a surge of patients with acute respiratory distress syndrome (ARDS) in intensive care units across the globe. As experience of managing patients with COVID-19-associated ARDS […]
» Read moreNontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline […]
» Read moreOne of the major challenges in treating obstructive sleep apnea (OSA) is to achieve adequate continuous positive airway pressure (CPAP) adherence. Telemonitoring has the potential to provide individualized management and […]
» Read moreExposure to zinc was suggested to be associated with pulmonary damage, but whether zinc exposure affects lung function remains unclear.To quantify the association between urinary zinc and lung function and […]
» Read moreLow-dose CT (LDCT) screening of high-risk smokers reduces lung cancer (LC) specific mortality. Determining screening eligibility using individualised risk may improve screening effectiveness and reduce harm. Here, we compare the […]
» Read moreThe most common antibiotic used to treat people with cystic fibrosis (PWCF) is inhaled tobramycin, administered as maintenance therapy for chronic Pseudomonas aeruginosa lung infections. While the effects of inhaled […]
» Read moreHealth-related quality of life (HRQoL) scores assess symptom burden in pulmonary arterial hypertension (PAH) but data regarding their role in prognostication and risk stratification are limited. We assessed these relationships […]
» Read moreNo large prospective data are available on ventilator-associated pneumonia (VAP) in patients with traumatic brain injury (TBI).To evaluate the incidence, timing and risk factors of VAP after TBI and its […]
» Read more129Xe ventilation MRI is sensitive to detect early CF lung disease and response to treatment. 129Xe-MRI could play a significant role in clinical trials and patient management. Here we present […]
» Read moreA variety of maintenance inhaler therapies are available to treat asthma and COPD. Patient-centric treatment choices require understanding patient preferences for the alternative therapies.A self-completed web-based discrete choice experiment was […]
» Read moreDecisions about lung cancer screening are inherently complex and create a need for methods to convey the risks and benefits of screening to patients.What kind of decision aids or tools […]
» Read moreEuropean Society of Cardiology and European Respiratory Society (ESC/ERS) guidelines include thermodilution cardiac index (TDCI) and mixed venous oxygen saturation (SvO2) as two of the three hemodynamic determinations used in […]
» Read moreHerpes simplex virus type 1 (HSV-1) is frequently detected in the bronchoalveolar lavage fluid (BAL) of mechanically ventilated patients.The aim of the study was to investigate whether antiviral therapy is […]
» Read morePrevious studies have yielded inconsistent findings regarding the association between obstructive sleep apnea (OSA) and cancer in humans.Is there an association between indices of sleep-disordered breathing severity and cancer incidence […]
» Read moreTreatment of hypoxemic respiratory failure (HRF) and Acute Respiratory Distress Syndrome (ARDS) is complex. Standardized management of HRF and ARDS may improve adherence to evidence informed practice and improve outcomes.To […]
» Read moreIn patients with bronchiectasis, airway clearance techniques (ACTs) are important management strategies.The primary objective was to describe differences in patients with bronchiectasis and productive cough who utilized ACTs and those […]
» Read morePrimary ciliary dyskinesia (PCD) is a heterogeneous disease with a diverse clinical and genetic spectrum among populations worldwide. Few cases of pediatric PCD have been reported from China.Clinical characteristics, laboratory […]
» Read morePulmonary exacerbations in cystic fibrosis are characterized by airway inflammation and may cause irreversible lung damage. Early identification of such exacerbations may facilitate early initiation of treatment, thereby potentially reducing […]
» Read moreThere are currently no reference standards for the development of competency in bronchoscopy.The aims of this study were to 1) develop learning curves for bronchoscopy skill development and 2) estimate […]
» Read morePrimary Sjogren’s syndrome (pSS) is an important cause of pulmonary arterial hypertension (PAH), which remains insufficiently studied and needs attention. This study aimed to investigate the clinical characteristics, risk factors, […]
» Read moreStereotactic Ablative Radiotherapy (SABR) is a well-established treatment for medically inoperable peripheral stage I non-small cell lung cancer (NSCLC). Previous non-randomised evidence supports SABR as an alternative to surgery, but […]
» Read moreVitamin C (500 mg·day-1) supplementation for pregnant smokers has been reported to increase newborn pulmonary function and infant forced expiratory flows (FEFs) at 3 months of age. Its effect on airway function […]
» Read moreRecent studies have demonstrated that high flow nasal cannula (HFNC) prevents intubation in acute hypoxic respiratory failure when compared to conventional oxygen therapy (COT). However, the data examining routine HFNC […]
» Read morePneumonia is the leading infection-related cause of death. Using simple clinical criteria and contemporary epidemiology to identify patients at high risk of nosocomial pneumonia should enhance prevention efforts and facilitate […]
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