Recent advances of dendrimers as multifunctional nano-carriers to combat breast cancer.

Bookmark this %label%

Breast cancer (BC) is a highly heterogeneous malignant carcinoma that is the most frequently occurring cancer in women. The major types of BC are luminal A, basal-like, luminal B, human […]

» Read more

How environmental enrichment balances out neuroinflammation on chronic pain and comorbid depression and anxiety disorders.

Bookmark this %label%

Depression and anxiety commonly occur in chronic pain states, and the co-existence of these diseases worsen outcomes for both disorders and may reduce treatment adherence and response. Despite the advances […]

» Read more

Integrating Resonator to Enhance Magnetometer Microelectromechanical System Implementation with ASIC Compatible CMOS 0.18 μm Process.

Bookmark this %label%

In this study, a multi-function microelectromechanical system (MEMS) was integrated with a MEMS oscillator, using the resonant frequency oscillation characteristics of the oscillator to provide the Lorentz current of the […]

» Read more

A Capacitive 3-Axis MEMS Accelerometer for Medipost: A Portable System Dedicated to Monitoring Imbalance Disorders.

Bookmark this %label%

The constant development and miniaturization of MEMS sensors invariably provides new possibilities for their use in health-related and medical applications. The application of MEMS devices in posturographic systems allows faster […]

» Read more

Evaluation of a Clinical Pharmacist Specialist Transition of Care Pathway to Manage Heart Failure Readmissions During a Provider Shortage.

Bookmark this %label%

Evidence supports scheduling early follow-up after heart failure (HF) hospitalization with a provider capable of managing hypervolemia. Often this service is provided by cardiologists or specialty nurse practitioners. Continuity or […]

» Read more

Evaluation of a Clinical Pharmacist Specialist Transition of Care Pathway to Manage Heart Failure Readmissions During a Provider Shortage.

Bookmark this %label%

Evidence supports scheduling early follow-up after heart failure (HF) hospitalization with a provider capable of managing hypervolemia. Often this service is provided by cardiologists or specialty nurse practitioners. Continuity or […]

» Read more

Continuous Etomidate for the Management of Cushing’s Syndrome Complicated by Pulmonary Nocardiosis.

Bookmark this %label%

Severe Cushing’s syndrome is associated with significant complications including opportunistic infections. In the setting of infection, urgent reduction of circulating cortisol is warranted and commonly used oral medications have a […]

» Read more

Revisiting Inorganic Nanoparticles as Promising Therapeutic Agents: A Paradigm Shift in Oncological Theranostics.

Bookmark this %label%

Cancer remains a global health problem largely due to a lack of effective therapies. Major cancer management strategies include chemotherapy, surgical resection, and radiation. Unfortunately, these strategies have a number […]

» Read more

A Study of Regulatory Challenges of Paediatric Oncology Phase I/II Trial Submissions and Guidance on Protocol Development.

Bookmark this %label%

The purpose of this study was to identify key deficiencies in paediatric oncology early phase clinical trial protocols in Germany and to provide guidance for efficient trial protocol development. A […]

» Read more

The development of inhibitors of LRRK2 as a therapeutic strategy for Parkinson’s disease: the current state of play.

Bookmark this %label%

Current therapeutic approaches for Parkinson’s disease (PD) are based around treatments that alleviate symptoms but do not slow or prevent disease progression. As such, alternative strategies are needed. A promising […]

» Read more

The role of nucleus of the solitary tract GLP1 and PrRP neurons in stress: anatomy, physiology, and cellular interactions.

Bookmark this %label%

Neuroendocrine, behavioural, and autonomic responses to stressful stimuli are orchestrated by complex neural circuits. The caudal nucleus of the solitary tract (cNTS) in the dorsomedial hindbrain is uniquely positioned to […]

» Read more

Combining modeling of drug uptake and release of cyclosporine in contact lenses to determine partition coefficient and diffusivity.

Bookmark this %label%

Ophthalmic drug delivery via eye drops is inefficient because only about 1-5% of the drug permeates the cornea during the short residence time of a few minutes. Contact lenses are […]

» Read more

Association between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID-19: an observational multicenter study.

Bookmark this %label%

Several medications commonly used for a number of medical conditions share a property of functional inhibition of acid sphingomyelinase (ASM), or FIASMA. Preclinical and clinical evidence suggest that the (ASM)/ceramide […]

» Read more

Low-Power Memristive Logic Device Enabled by Controllable Oxidation of 2D HfSe2 for In-Memory Computing.

Bookmark this %label%

Memristive logic device is a promising unit for beyond von Neumann computing systems and 2D materials are widely used because of their controllable interfacial properties. Most of these 2D memristive […]

» Read more

Assessing the Impact of FDA Breakthrough Therapy Designation Timing on Trial Characteristics and Development Speed.

Bookmark this %label%

Congress created the Breakthrough Therapy designation in 2012 to expedite drug development and review through efficient clinical trial design and intensive interaction with United States (US) Food and Drug Administration […]

» Read more
1 2 3 4 5 568