This retrospective review assesses the safety and efficacy of subcutaneous lidocaine infusions for complex cancer pain, in a specialist palliative care unit. A retrospective chart review was undertaken of 18 […]» Read more
The value of interdisciplinary treatment for sickness absence in chronic pain: a nationwide register-based cohort study.
Interdisciplinary treatment (IDT) is an internationally recommended intervention for chronic pain, despite inconclusive evidence of its effects on sickness absence.With data from 25,613 patients in Swedish specialist healthcare, we compared […]» Read more
Skin Closure Technique and Postprocedural Pain after Spinal Cord Stimulator Implantation: A Retrospective Review.
Spinal cord and dorsal root ganglion stimulation are minimally invasive surgical techniques used to treat an array of chronic pain disorders. There is a paucity of data related to defining […]» Read more
The Incidence of Mental Disorders Increases over Time in Patients with Cancer Pain: Data from a Retrospective Cohort Study.
It is well known that cancer patients more seldom have a psychiatric disorder than noncancer patients with chronic pain. Conversely, earlier studies have suggested that, at the psychiatric level, long-term […]» Read more
Slowing in peak-alpha frequency recorded after experimentally-induced muscle pain is not significantly different between high and low pain-sensitive subjects.
Peak alpha frequency (PAF) reduces during cutaneous pain, but no studies have investigated PAF during movement-related muscle pain. Whether high-pain sensitive (HPS) individuals exhibit a more pronounced PAF response to […]» Read more
The Role of Skin Mast Cells in Acupuncture Induced Analgesia in Animals: A Preclinical Systematic Review and Meta-analysis.
While mast cells (MCs) are previously well-known as a pathological indicator of pain, their role in alleviating pain is recently emerged in acupuncture research. Thus, this study systematically reviews the […]» Read more
Treatment outcomes for migraine and other chronic headache and pain conditions typically demonstrate modest results. A greater understanding of underlying pain mechanisms may better inform treatments and improve outcomes. Increased […]» Read more
Despite extensive research on the development and risk factors of chronic pain, the process of recovery from chronic pain in later life has been rarely studied. We estimated the recovery […]» Read more
This study investigated whether there are gender differences in attention to bodily expressions of pain and core emotions. Three experiments are reported using the attentional dot probe task. Images of […]» Read more
Characteristics and Network Influence of Providers Involved in the Treatment of Patients with Chronic Back, Neck or Joint Pain in Arkansas.
Increasing emphasis on guidelines and prescription drug monitoring programs highlight the role of healthcare providers in pain treatment. Objectives of this study were to identify characteristics of key players and […]» Read more
Relevant factors for neurologists to define effectiveness of migraine preventive drugs and take decisions on treatment. My-LIFE European Delphi survey.
Clinical guidelines agree that preventive treatment should be considered in patients with uncontrolled migraine despite acute medications or patients with ≥4 migraine days per month. However, the criteria to define […]» Read more
Measuring pain in oncology outpatients: Numeric Rating Scale versus acceptable/non-acceptable pain. A prospective single center study.
During all stages of oncologic diseases, pain is still a major problem. The Numeric Rating Scale (NRS) is one of the most frequently used tools for pain assessment although interpretation […]» Read more
Pain and inflammation are common experiences following ocular surgery and, if uncontrolled, can compromise patients’ vision, functioning and quality of life. Corticosteroid drugs are available to manage inflammation and discomfort […]» Read more
The role of the observers’ perception of a model’s self-confidence in observationally induced placebo analgesia.
The aim of this study was to investigate the effect on observationally acquired placebo analgesia of a model’s self-confidence as well as the observer’s self-esteem and self-efficacy. In addition, we […]» Read more
Pain remains a global health challenge affecting approximately 1.5 billion people worldwide. Pain has been an implicit variable in the equation of human life for many centuries considering different types […]» Read more
Economic long-term effects of intensive interdisciplinary pain treatment in pediatric patients with severe chronic pain: Analysis of claims data.
Chronic pain in children and adolescents gives rise to high health care costs. Successful treatment is supposed to reduce the economic burden. The objective of this study was to determine […]» Read more
Green light antinociceptive and reversal of thermal and mechanical hypersensitivity effects rely on endogenous opioid system stimulation.
Benefits of phototherapy were characterized in multiple diseases including depression, circadian rhythm disruptions, and neurodegeneration. Studies on migraine and fibromyalgia patients revealed that green light-emitting diodes (GLED) exposure provides a […]» Read more
Nerve excitability and neuropathic pain is reduced by BET protein inhibition after spared nerve injury.
Neuropathic pain is a common disability produced by enhanced neuronal excitability after nervous system injury. The pathophysiological changes that underlie the generation and maintenance of neuropathic pain require modifications of […]» Read more
Many online interventions for paediatric chronic pain have been developed and evaluated. In accordance with the biopsychosocial model, the recommended treatment approach for chronic pain is multidisciplinary. Despite this, multidisciplinary […]» Read more
The longitudinal association between persistent moderate to severe pain and subsequent long-term cognitive decline remains inconclusive.Study population came from the English Longitudinal Study of Ageing, an ongoing prospective and nationally […]» Read more
Revealing the time course of laser evoked potential habituation by high temporal resolution analysis.
Reduced laser evoked potential (LEP) habituation indicates abnormal central pain processing. But the paradigm (4 stimulation blocks a 25 stimuli) is time-consuming and potentially omits important information on the exact […]» Read more
The Effect of a Pain Educational Video Intervention upon Child Pain-Related Outcomes: a Randomized Controlled Study.
Pain neuroscience education (PNE) has received increasing research attention demonstrating beneficial effects on pain-related outcomes in adults. Conversely, studies on the effectiveness of PNE in children are scarce.The current study […]» Read more
Impact of duloxetine on succinylcholine-induced postoperative myalgia after direct microlaryngoscopic surgeries: Randomized controlled double-blind study.
Succinylcholine is a preferred muscle relaxant for rapid sequence intubation. Postoperative myalgia (POM) is one of its commonest adverse effects with unknown pathogenesis. Various modalities were examined to reduce POM. […]» Read more
Lead Migration and Fracture Rate in Dorsal Root Ganglion Stimulation Using Anchoring and Non-Anchoring Techniques: A Multicenter Pooled Data Analysis.
Dorsal root ganglion stimulation (DRG-S) is a neuromodulation technique introduced in the last decade with evolving implant methods. Initial prospective research found low incidences of lead migration and lead fracture […]» Read more
The Greek Neuropathic Pain Registry (Gr.NP.R.): The structure and objectives of the sole Neuropathic Pain Registry in Greece.
Neuropathic pain (NP) is a complex condition that impairs the patients’ quality of life. Registries are useful tools, increasingly used as they provide high-quality data. This article aims to describe […]» Read more
Decreased Pain Sensitivity and Alterations of Cerebrospinal Fluid and Plasma Inflammatory Mediators After Total Hip Arthroplasty in Patients with Disabling Osteoarthritis.
Proinflammatory mechanisms are implicated in pain states. Recent research indicates that osteoarthritis (OA) patients with signs of central sensitization exhibit elevated cerebrospinal fluid (CSF) levels of interferon gamma-induced protein 10 […]» Read more
Physical, emotional and social pain communication by patients diagnosed and living with multiple myeloma.
Aim: To describe physical, social and emotional aspects of pain self-reported by patients with multiple myeloma (MM), and patient-physician communication of physical pain. Materials & methods: We analyzed self-reported data from […]» Read more
To answer the question: among observational studies, is there any association between primary headaches and bruxism in adults?A systematic review of observational studies was performed. The search was performed in […]» Read more
Association of Hormonal Contraceptive Use with Headache and Temporomandibular Pain: The OPPERA Study.
To determine the relationship between hormonal contraceptive (HC) use and painful symptoms, particularly those associated with headache and painful temporomandibular disorders (TMD).Data from the Orofacial Pain: Prospective Evaluation and Risk […]» Read more
Headache Attributed to Temporomandibular Disorders: Axis I and II Findings According to the Diagnostic Criteria for Temporomandibular Disorders.
To analyze Axis I and II findings of patients diagnosed as having painful temporomandibular disorder (TMD) with headache attributed to TMD (HAattrTMD) in order to assess whether HAattrTMD is associated […]» Read more