Intracranial injuries on computed tomography head scans in infants investigated for suspected physical abuse: a retrospective review.

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UK national guidelines recommend that investigation of infants (aged <12 months) with suspected physical abuse should always include CT head scans. Such imaging carries small but recognised risks from radiation […]

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Cross-cultural adaptation of the Participation and Environment Measure for Children and Youth (PEM-CY) into German: a qualitative study in three countries.

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Concepts such as participation and environment may differ across cultures. Consequently, to use a measure like the Participation and Environment Measure for Children and Youth (PEM-CY) in other than the […]

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The SIOP-Renal Tumour Study Group consensus statement on flank target volume delineation for highly conformal radiotherapy.

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For decades, radiotherapy with two opposing photon beams has been the standard technique used to cover the flank target volume in paediatric patients with renal tumours. Nowadays, many institutes are […]

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Prevalence of gout and asymptomatic hyperuricemia in the pediatric population: a cross-sectional study of a Japanese health insurance database.

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Although gout is rare in children, chronic sustained hyperuricemia can lead to monosodium urate deposits progressing to gout, just as in adults. This study assessed prevalence and characteristics of gout […]

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Capillary blood reference intervals for platelet parameters in healthy full-term neonates in China.

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No consensus has been reached on capillary blood reference intervals for platelet parameters in full-term neonates. We aimed to establish neonatal capillary blood reference intervals for platelet parameters and evaluate […]

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A sex/gender perspective on interventions to promote children’s and adolescents’ overall physical activity: results from genEffects systematic review.

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To evaluate the effects of interventions on children’s and adolescents’ overall physical activity (PA) for boys and girls separately and to appraise the extent to which the studies haven taken […]

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A scoping review of physical activity and screen time guidelines for use in Outside School Hours Care.

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Globally, millions of children attend Outside School Hours Care. Children’s activity in this setting is critical to meeting daily physical activity recommendations. Guidelines are evidence-based statements intended to optimise practice. […]

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Interferon-γ Release Assays for Tuberculosis Infection Diagnosis in Refugees <5 Years Old.

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New guidelines support using interferon-γ release assays (IGRAs) in children ≥2 years for diagnosis of latent tuberculosis infection (LTBI). However, lack of experience in young children and concern that IGRAs […]

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Consensus guidelines on managing Rett syndrome across the lifespan.

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Rett syndrome (RTT) is a severe neurodevelopmental disorder with complex medical comorbidities extending beyond the nervous system requiring the attention of health professionals. There is no peer-reviewed, consensus-based therapeutic guidance […]

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Clinical practice guideline on the prevention and management of neonatal extravasation injury: a before-and-after study design.

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Extravasation injury resulting from intravenous therapies delivered via peripheral intravenous catheters or umbilical and peripherally inserted central venous catheters is a common iatrogenic complication occurring in neonatal intensive care units. […]

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Positive End-Expiratory Pressure in Newborn Resuscitation Around Term: A Randomized Controlled Trial.

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International guidelines for resuscitation recommend using positive end-expiratory pressure (PEEP) during ventilation of preterm newborns. Reliable PEEP-valves for self-inflating bags have been lacking, and effects of PEEP during resuscitation of […]

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A qualitative study reporting maternal perceptions of the importance of play for healthy growth and development in the first two years of life.

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In order for infants and toddlers to meet recommended movement guidelines, their caregivers need to encourage play daily. This study used a qualitative approach to understand how mothers perceive and […]

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Feeding practices in 6-24-month-old children with chronic cholestatic liver diseases: a mixed-method study.

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Children with chronic cholestatic liver diseases have a high risk of malnutrition. However, nutritional management in China has received little attention, and there has been limited evidence regarding improving these […]

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Admission platelet count and indices as predictors of outcome in children with severe Sepsis: a prospective hospital-based study.

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Sepsis is still one of the main causes of infants and children mortality especially in developing, economically challenged countries with limited resources. Our objective in this study was to determine, […]

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