The growing prevalence of pediatric mental and behavioral health disorders, coupled with scarce psychiatric resources, has resulted in a substantial increase in the number of youth waiting in emergency departments […]» Read more
Gender-incongruent (GI) youth have high rates of mental health problems. Although gender-affirming medical care (GAMC) provides psychological benefit, some GI youth present to care at older ages. Whether a relationship […]» Read more
The youngest children in a classroom are at increased risk of being medicated for attention-deficit/hyperactivity disorder (ADHD). We examined the association between children’s birth month and ADHD medication rates in […]» Read more
Strong evidence for a causal role of environmental factors in a congenital anomaly is still difficult to produce. The collection of statistical data is crucial for gaining a better understanding […]» Read more
Toothbrush deterioration and parents’ suggestions to improve the design of toothbrushes used by children with special care needs.
Biting objects was a parafunctional oral habit among children with special care needs. Chewing or biting toothbrushes could expedite the process of toothbrush wear. However, few studies evaluated the deterioration […]» Read more
Citrin deficiency (CD) is a recessive metabolic disease caused by biallelic pathogenic variants in SLC25A13. Although previous studies have reported ketosis in CD, it was observed at the time of […]» Read more
To explore the ability of an interactive screening tool to identify cognitive delay in children aged 18 to 24 months.Children were assessed using the Bayley Scale of Infant and Toddler […]» Read more
Pulse oximetry curves in healthy children living at moderate altitude: a cross-sectional study from the Ecuadorian Andes.
In populations above 3,000 meters above sea level (m.a.s.l.) normal values of oxygen saturation (SpO2) above 90% have been reported. Few studies have been conducted in cities of moderate altitude […]» Read more
Ultrasonographic diagnosis, classification, and treatment of cervical lymphatic malformation in paediatric patients: a retrospective study.
To explore the imaging features, key diagnostic points, classification, treatment, and prognosis of cervical lymphatic malformation.Overall, 320 patients diagnosed with cervical lymphatic malformation were retrospectively analysed in our hospital between […]» Read more
To determine the natural history of pediatric hypertension.We conducted a 72-month retrospective cohort study among 165 primary care sites. Blood pressure measurements from two consecutive 36 month periods were compared.Among […]» Read more
Self-administration of adrenaline for anaphylaxis during in-hospital food challenges improves health-related quality of life.
To assess the impact of anaphylaxis on health-related quality of life (HRQL) and self-efficacy in food-allergic patients undergoing in-hospital food challenge.Secondary analysis of a randomised controlled trial.Specialist allergy centre.Peanut-allergic young […]» Read more
Does implementation of the PECARN rules for minor head trauma improve patient-centered outcomes in a lower resource emergency department: a retrospective cohort study.
Managing children with minor head trauma remains challenging for physicians who evaluate for the need for computed tomography (CT) imaging for clinically important traumatic brain injury (ciTBI) identification. The Pediatric […]» Read more
Obscure gastrointestinal bleeding caused by congenital enteropathy in a Chinese young child-a case report.
SLCO2A1 was recently reported to cause nonspecific ulcers at small bowel, it was named as chronic enteropathy associated with SLCO2A1 (CEAS). It was rarely reported beyond the Japanese population.A 4-year-5-month […]» Read more
Efficacy of scopolamine transdermal patch in children with sialorrhea in a pediatric tertiary care hospital.
Drooling is common in children with neurological disorders, but its management is very challenging, Scopolamine transdermal patch (STP) appears to be useful in controlling drooling, although it is not approved […]» Read more
Deleterious effects of malaria in pregnancy on the developing fetus: a review on prevention and treatment with antimalarial drugs.
All malaria infections are harmful to both the pregnant mother and the developing fetus. One in ten maternal deaths in malaria endemic countries are estimated to result from Plasmodium falciparum […]» Read more
Malaria disproportionately affects children younger than 5 years. Falciparum malaria is responsible for more than 200 000 child deaths per year in Africa and vivax malaria is well documented as a […]» Read more
The National Institutes of Health’s Environmental Influences on Child Health Outcomes (ECHO) program aims to study high-priority and high-impact pediatric conditions. This broad-based health initiative is unique in the National […]» Read more
Potential long-lasting adverse effects of child maltreatment have been widely reported, although little is known about the distinctive long-term impact of differing types of maltreatment. Our objective for this special […]» Read more
Early Hypoxic Respiratory Failure in Extreme Prematurity: Mortality and Neurodevelopmental Outcomes.
To evaluate the survival and neurodevelopmental impairment (NDI) in extremely low birth weight (ELBW) infants at 18 to 26 months with early hypoxemic respiratory failure (HRF). We also assessed whether […]» Read more
Primary adjunctive corticosteroid therapy is associated with improved outcomes for patients with Kawasaki disease with coronary artery aneurysms at diagnosis.
Patients with Kawasaki disease (KD) with coronary artery enlargement at diagnosis are at the highest risk for persistent coronary artery aneurysms (CAAs) and may benefit from primary adjunctive anti-inflammatory therapy […]» Read more
For healthy individuals, it is increasingly accepted that lung function follows along an individual percentile established early in life and that the level of maximal function reached as a young […]» Read more
Genetic testing is recommended for individuals with autism spectrum disorder (ASD). Pathogenic yield varies by clinician and/or patient characteristics. Our objectives were to determine the pathogenic yield of genetic testing, […]» Read more
Involvement with Child Protective Services (CPS) provides an opportunity to recognize those children at risk for ongoing adverse childhood experiences (ACEs). The relationship between ACEs and child health among CPS-involved […]» Read more
Vaccine-preventable diseases (VPD) are a significant risk to paediatric solid organ transplant (SOT) recipients on lifelong immunosuppressive therapy. Children progressing to end-stage organ dysfunction are unable to mount a robust […]» Read more
There are controversies about the correlation between higher levels of thyroid stimulating hormone (TSH) and dyslipidemia in children. This study was designed to assess the relation between lipid profile components […]» Read more
Blood lead concentration and its associated factors in preschool children in eastern Iran: a cross-sectional study.
Lead is a toxic metal that affects almost every organ in the body. Children are more susceptible to lead toxicity because they ingest non-food items (pica), have oral exploratory habits, […]» Read more
The following is the winning submission from the Fourth Annual Section on Pediatric Trainees Essay Competition. This year’s competition was informed by the 2019-2020 Section on Pediatric Trainees Advocacy Campaign: […]» Read more
Although the airway microbiota is a highly dynamic ecology, the role of longitudinal changes in airway microbiota during early childhood in asthma development is unclear. We aimed to investigate the […]» Read more
Adolescents with problematic substance use (SU) are at risk for far-reaching adverse outcomes.Synthesize the evidence regarding the effects of brief behavioral interventions for adolescents (12-20 years) with problematic SU.We conducted […]» Read more
The standard schedule of national immunization programs for infants may not be sufficient to protect extremely and very preterm infants.To evaluate the immunogenicity of routine vaccinations administered to preterm infants.A […]» Read more