Diversity of Ocular Surface Bacterial Microbiome Adherent to Worn Contact Lenses and Bacterial Communities Associated With Care Solution Use.

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This study assessed microbiome adherent to contact lenses and defined the bacterial communities associated with use of lens care solutions.Among 84 lenses screened for adherent ocular surface bacterial microbiome using […]

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Systematic Review on Therapeutic Strategies to Minimize Corneal Stromal Scarring After Injury.

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To evaluate recent studies on available and experimental therapies in preventing or minimizing corneal stromal scarring after injury.We performed an Entrez PubMed literature search using keywords “cornea,” “scarring,” “haze,” “opacity,” […]

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The Lens Opacities Classification System III Grading in Irradiated Uveal Melanomas to Characterize Proton Therapy-Induced Cataracts.

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To evaluate the use of the Lens Opacities Classification System III grading (LOCS III) for the characterization of radiation-induced cataract, and to correlate the proton beam projection onto the lens […]

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Evaluation of the antioxidant effects of different histone deacetylase inhibitors (HDACis) on human lens epithelial cells (HLECs) after UVB exposure.

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To compare the protective effects of the histone deacetylase inhibitors (HDACis) β-hydroxybutyrate (βOHB), trichostatin A (TSA), suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA) on human lens epithelial cells(HLECs) following […]

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Optical coherence tomography and optical coherence tomography angiography in uveitis: A review.

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Optical coherence tomography (OCT) has dramatically changed the understanding and management of uveitis and other ocular conditions. Currently, OCT angiography (OCTA) combines structural information with the visualization of blood flow […]

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Deep Anterior Lamellar Keratoplasty for Keratoconus: Multisurgeon Results.

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To examine clinical outcomes in deep anterior lamellar keratoplasty (DALK) for keratoconus using contemporary techniques in a multisurgeon public healthcare setting.Consecutive, retrospective case series.Setting: Moorfields Eye Hospital, London, United Kingdom.Consecutive […]

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Estimated Prevalence and Incidence of Dry Eye Disease Based on Coding Analysis of a Large, All-age United States Health Care System.

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To assess overall prevalence, annual prevalence, and incidence of dry eye disease (DED) in a large, representative population in the United States.Prevalence and incidence study.Retrospective analysis using the Department of […]

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Near-Infrared Autofluorescence in Choroideremia: Anatomic and Functional Correlations.

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To investigate near-infrared fundus autofluorescence (NIR-AF) characteristics in patients with choroideremia and to correlate these with anatomic and functional parameters.Retrospective, observational case series.In this multicenter study, 43 consecutive choroideremia patients […]

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Six-year incidence and progression of diabetic retinopathy in Indian adults: the Singapore Indian Eye study.

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Diabetes is a major public health problem in migrants and ethnic minorities worldwide. We determined the incidence and risk factors of diabetic retinopathy (DR) in migrant Indians living in Singapore.We […]

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Evidence of Müller Glial Dysfunction in Patients with Aquaporin-4 Immunoglobulin G-Positive Neuromyelitis Optica Spectrum Disorder.

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To compare functional and structural changes in the retina in patients with aquaporin-4 immunoglobulin G (AQP4-IgG)-positive neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS).Cross-sectional study; biochemical study of human […]

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Microperimetry in age-related macular degeneration: association with macular morphology assessed by optical coherence tomography.

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Microperimetry is a technique that is increasingly used to assess visual function in age-related macular degeneration (AMD). In this study, we aimed to evaluate the relationship between retinal sensitivity measured […]

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Pyogenic granuloma associated with conjunctival epithelial neoplasia: report of nine cases.

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To systematically describe the clinical and histopathological features of a case series of conjunctival carcinomatous lesions underlying as-and also masquerading-pyogenic granuloma.Nine cases of conjunctival carcinomatous lesions underlying a pyogenic granuloma […]

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Refractory follicular conjunctival lesions: overlook as just inflammation or not?

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To report the clinical manifestations of 199 patients with suspected conjunctival lymphoma, the associations between these features and the pathological diagnoses, and the prognosis of conjunctival lesions during long-term follow-up.We […]

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Areal summed corneal power shift is an important determinant for axial length elongation in myopic children treated with overnight orthokeratology.

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The myopia control effect of orthokeratology (OK) varies among individuals. The variation might relate to the proposed ‘areal summation effect’ of lens-induced visual signals. The current study evaluated the areal […]

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Ziv-aflibercept versus bevacizumab administration prior to diabetic vitrectomy: a randomised and controlled trial.

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To compare the effectiveness of intravitreal ziv-aflibercept (IVZ) to intravitreal bevacizumab (IVB) administered preoperatively to patients undergoing pars plana vitrectomy (PPV) for severe manifestations of proliferative diabetic retinopathy (PDR).Randomised clinical […]

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Risk-stratified systemic surveillance in uveal melanoma.

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Molecular prognostication provides clinically applicable prognostic information for patients with uveal melanoma. Most ocular oncologists recommend intensive metastatic surveillance for patients with high-risk tumours. However, socioeconomic variables may limit a […]

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Association of human antigen class I genes with cold medicine-related Stevens-Johnson syndrome with severe ocular complications in a Korean population.

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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are a spectrum of diseases that cause an acute vesiculobullous reaction in the skin and mucous membranes. The occurrence of these diseases […]

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