The c.1102C>T, p.(Gln368Ter) variant in the myocilin (MYOC) gene is a known risk allele for glaucoma. It is the most common MYOC risk variant for glaucoma among individuals of European […]» Read more
Serratia marcescens is a frequent ocular bacterial pathogen implicated in keratitis, endophthalmitis, and conjunctivitis. We evaluated the risk factors and treatment outcomes of ocular infections due to S. marcescens.In this […]» Read more
Quantitative visual tests in primary open-angle glaucoma patients according to three different lights with different color-rendering index.
To compare quantitative visual tests, such as visual acuity, contrast sensitivity, and color vision tests in patients with primary open-angle glaucoma (POAG) patients according to three different light systems with […]» Read more
To compare dynamic ranges and steps to measurement floors of peripapillary and macular metrics from a complex signal-based optical microangiography (OMAGC) optical coherence tomography angiography (OCTA) device for glaucoma with […]» Read more
Ab-externo MicroShunt versus Trabeculectomy in Primary Open-Angle Glaucoma: 1-year Results from a 2-year Randomized, Multicenter Study.
To compare the effectiveness and safety of the MicroShunt versus trabeculectomy in patients with primary open-angle glaucoma (POAG).One-year results from a 2-year, prospective, randomized, multicenter, non-inferiority study (NCT01881425) conducted in […]» Read more
To identify sociodemographic factors and comorbid conditions associated with receiving keratoplasty for keratoconus (KCN) DESIGN: Retrospective, cross-sectional study METHODS: Health records of KCN patients aged <65 years from 2011 to […]» Read more
To determine the unplanned return to OR rate within 180 days and at any time postoperatively after valved and non-valved tube shunt surgery DESIGN: : Retrospective case-control study METHODS: : […]» Read more
Vertical position of the central retinal vessel in the optic disc and its association with the site of visual field defects in glaucoma.
To investigate association between the vertical position of the central retinal vessel (CRV) within the optic nerve head (ONH) and site of visual field defects (VFDs) in glaucoma.Cross-sectional study.Vertical position […]» Read more
Topical prostaglandin analogue use and cystoid macular oedema following uneventful cataract surgery: a randomised control trial.
The association between the development of cystoid macular oedema (CMO) following uneventful cataract surgery and prostaglandin analogue (PGA) therapy has not been fully determined. The study aim was to investigate […]» Read more
Endophthalmitis Caused by Streptococcus:Clinical Outcomes and Antimicrobial Susceptibilities 2014-2019.
To report the clinical settings, antibiotic susceptibilities, and outcomes of streptococcal endophthalmitis.Retrospective case series evaluating culture-positive streptococcal endophthalmitis from January 1, 2014, to December 31, 2019.Thirty-eight eyes met study criteria. […]» Read more
Higher contrast thresholds for vanishing optotype recognition in macular visual fields among glaucoma patients: a structure-function analysis.
We aimed to explore the impact of glaucomatous macular damage, specifically retinal ganglion cell (RGC) loss, on macular pattern vision measured by the vanishing optotype (VO) recognition contrast threshold.Seventy-two patients […]» Read more
To examine presentation, management and long-term sequelae of ocular hypertension and uveitic glaucoma.Retrospective observational study of all subjects with uveitic glaucoma or ocular hypertension seen in Auckland uveitis clinics over […]» Read more
Glaucoma is a leading cause of global blindness, especially preventable blindness. The increased prevalence of glaucoma has led to a growing demand for newer, safer, more rapid, and simpler treatments […]» Read more
Interpretation of change scores for the National Eye Institute Visual Function Questionnaire-25: the minimally important difference.
To estimate the minimally important difference (MID) in change in National Eye Institute Visual Function Questionnaire-25 (VFQ-25) composite score using methods aligned with patient perception.Retrospective analysis of prospectively collected data […]» Read more
Novel utilisation of ultrawide-field fundus photography for detecting retinal nerve fibre layer defects in glaucomatous eyes.
Evaluation of the retinal nerve fibre layer (RNFL) is important for identifying glaucomatous damage. Ultrawide-field fundus photography (UWP) imaging is increasingly used in the ophthalmological field; however, it is unknown […]» Read more
Importance and severity dependence of physical activity by GPS-tracked location in glaucoma patients: GPS-tracked physical activity in glaucoma.
To quantify the association of visual field (VF) damage on physical activity away-from-home, per away-from-home excursion, and at home.Prospective cohort study.Among 229 participants with glaucoma or suspected glaucoma, severity of […]» Read more
The Boston Keratoprosthesis Type 1 was pioneered by Claes Dohlman several decades ago. Since its inception, the device has undergone multiple revisions to address challenges associated with retroprosthetic membrane formation, […]» Read more
Pseudoexfoliation (PXF) syndrome is the most common cause of secondary glaucoma worldwide. This systemic disorder causes further damage to the optic nerve and ultimately increases the need for surgical interventions. […]» Read more
The prevalence of myopia is increasing around the world, stimulating interest in methods to slow its progression. The primary justification for slowing myopia progression is to reduce the risk of […]» Read more
The Pediatric Eye Disease Investigator Group Cataract Registry provides a multicenter assessment of visual outcomes and complications after lensectomy for traumatic pediatric cataract.To report visual acuity (VA) and the cumulative […]» Read more
Environmental features contributing to falls in persons with vision impairment: The role of home lighting and home hazards.
To evaluate whether home hazards and lighting levels are associated with higher fall rates in adults with varying degrees of visual field (VF) damage from glaucoma.Participants with diagnosed or suspected […]» Read more
Laser in Glaucoma and Ocular Hypertension Trial (LIGHT) in China A Randomized Controlled Trial: Design and Baseline Characteristics.
To describe the baseline characteristics of a trial to evaluate whether selective laser trabeculoplasty (SLT), as a first-line treatment, provides superior economic and health-related quality of life outcomes to medical […]» Read more
Viability of performing multiple 24-2 visual field examinations at the same clinical visit: the Frontloading Fields Study (FFS).
To assess the viability in terms of time taken for testing and repeatability of frontloading (performing multiple perimetric examinations) in a single clinic visit.Reliability enhancement analysis.329 healthy, glaucoma suspect, and […]» Read more
Automated detection of glaucoma with interpretable machine learning using clinical data and multi-modal retinal images.
To develop a multi-modal model to automate glaucoma detection.Development of a machine-learning glaucoma detection model.We selected a study cohort from the UK Biobank dataset with 1193 eyes of 863 healthy […]» Read more
Diagnosis of cytomegalovirus corneal endotheliitis using surgically removed Descemet’s membrane and endothelium despite negative results with aqueous humor PCR: a case report.
Cytomegalovirus (CMV) has been known to cause unilateral corneal endotheliitis with keratic precipitates and localized corneal edema, iridocyclitis, and secondary glaucoma. CMV endotheliitis is diagnosed based on clinical manifestations and […]» Read more
The aim of the study was to examine the effect of the COVID-19 pandemic on glaucoma surgical practices within the UK.A cross-sectional online survey was distributed to all consultant glaucoma […]» Read more
Ten-year-and-beyond longitudinal change of ß-zone parapapillary atrophy in glaucoma: association with retinal nerve fibre layer defect.
To investigate the longitudinal change of localised retinal nerve fibre layer (RNFL) defects associated with change of ß-zone parapapillary atrophy (PPA) in primary open-angle glaucoma (POAG) eyes.POAG patients with a […]» Read more
Trabeculectomy with mitomycin C alone or coupled with intracamerular bevacizumab? A 2-year comparative study.
To compare outcomes of primary trabeculectomy using either mitomycin C (MMC) alone versus MMC augmented with intracamerular bevacizumab in patients with open-angle glaucoma.Retrospective, cohort, two-centre, comparative study. Patients’ data were […]» Read more
To compare spectral-domain optical coherence tomography (SDOCT) measured circumpapillary retinal nerve fiber layer (cpRNFL) among four glaucomatous optic disc phenotypes in early glaucoma.Clinical cohort study METHODS: In this study, 218 […]» Read more
Selecting reliable visual field (VF) test takers could improve the power of randomised clinical trials in glaucoma. We test this hypothesis via simulations using a large real world dataset.Methodology analysis: […]» Read more