Anterior segment reconstruction with artificial iris and Descemet membrane endothelial keratoplasty: a staged surgical approach.

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To describe a surgical approach that involves anterior segment reconstruction with CustomFlex Artificial Iris (CAI; HumanOptics, Erlangen, Germany) followed by Descemet membrane endothelial keratoplasty (DMEK) in complex eyes with corneal […]

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Comparison of clinical outcomes of conbercept versus ranibizumab treatment for retinopathy of prematurity: a multicentral prospective randomised controlled trial.

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To compare the recurrence rate and surgical complications of retinopathy of prematurity (ROP) between patients treated with intravitreal injection of conbercept (IVC) and intravitreal injection of ranibizumab (IVR) within 6 […]

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Cost-effectiveness analysis of preloaded versus non-preloaded Descemet membrane endothelial keratoplasty for the treatment of Fuchs endothelial corneal dystrophy in an academic centre.

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To determine the cost-effectiveness of preloaded Descemet membrane endothelial keratoplasty (pDMEK) versus non-preloaded DMEK (n-pDMEK) for the treatment of Fuchs endothelial corneal dystrophy (FECD).From a societal and healthcare perspective, this […]

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Enrichment of IGF-1R and PPARγ signalling pathways in orbital inflammatory diseases: steps toward understanding pathogenesis.

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Orbital inflammatory disease (OID) encompasses a wide range of pathology including thyroid-associated orbitopathy (TAO), granulomatosis with polyangiitis (GPA), sarcoidosis and non-specific orbital inflammation (NSOI), accounting for up to 6% of […]

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Impact of incident age-related macular degeneration and associated vision loss on vision-related quality of life.

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We examined the associations between the 6-year incidence of age-related macular degeneration (AMD) and vision-related quality of life (VRQoL), and the contribution of presenting visual acuity (VA), in an Asian […]

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A rare case of unilateral Cogan’s anterior internuclear ophthalmoplegia, upgaze palsy and ataxia caused by dorsal tegmentum lesion at pontomesencephalic junction.

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Cogan’s anterior internuclear ophthalmoplegia (INO) is characterized by INO with inability to converge and commonly thought to be due to rostral midbrain lesion. A lesion outside midbrain that causes unilateral […]

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Haem relieves hyperoxia-mediated inhibition of HMEC-1 cell proliferation, migration and angiogenesis by inhibiting BACH1 expression.

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Hyperoxia-mediated inhibition of vascular endothelial growth factor (VEGF) in the retina is the main cause of impeded angiogenesis during phase I retinopathy of prematurity (ROP). Human retinal angiogenesis involves the […]

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Outcomes of bicanalicular nasal stent inserted by sheath-guided dacryoendoscope in patients with lacrimal passage obstruction: a retrospective observational study.

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The dacryoendoscope is the only instrument that can observe the luminal side of the lacrimal passage with minimal invasiveness. It was developed to treat lacrimal passage obstructions by inserting a […]

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Survival in small choroidal melanocytic lesions with risk factors managed by initial observation until detection of tumour growth.

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Main objective was to describe metastatic and survival rates in patients with small choroidal melanocytic lesions initially managed by observation.Retrospective, observational study of consecutive cases recruited from 2001 through 2018, […]

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Assessing accommodative presbyopic biometric changes of the entire anterior segment using single swept-source OCT image acquisitions.

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To evaluate biometric changes throughout the anterior chamber during accommodation and presbyopia using single image acquisition swept-source anterior-segment optical coherence tomography (AS-OCT).Anterior-segment images were obtained using a new swept-source AS-OCT […]

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Early Experience With Brolucizumab Treatment of Neovascular Age-Related Macular Degeneration.

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Outcome data are limited regarding early experience with brolucizumab, the most recently approved anti-vascular endothelial growth factor (VEGF) agent for the treatment of neovascular age-related macular degeneration (nAMD).To report clinical […]

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Longitudinal course of consecutive esotropia in children following surgery for basic-type intermittent exotropia.

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To evaluate the longitudinal course of consecutive esotropia following surgery for basic-type intermittent exotropia.Patients who underwent surgery (bilateral lateral rectus muscle recession [BLR] or unilateral lateral rectus muscle recession-medial rectus […]

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Post-traumatic endophthalmitis caused by streptococcus species in preschool children: clinical features, antibiotic susceptibilities and outcomes.

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Streptococcus is a common cause of post-traumatic endophthalmitis in children. This study aimed to analyse the clinical features, antibiotic susceptibilities and outcomes of traumatic endophthalmitis caused by streptococcus in preschool […]

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Real-Time In Vivo Assessment of Retinal Reattachment in Humans using Swept-Source Optical Coherence Tomography.

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To assess the in vivo physiology of retinal reattachment in humans using swept-source optical coherence tomography (SS-OCT) in real-time.Prospective case series.Fifteen consecutive patients with fovea-involving rhegmatogenous retinal detachment undergoing pneumatic […]

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Scleral Fixation of Carlevale Intraocular Lens in Children: A Novel Tool in Correcting Aphakia With No Capsular Support.

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To report the clinical outcomes of the use of a novel, specially designed, scleral-fixated intraocular lens (IOL) for the correction of aphakia in the absence of capsular support of variable […]

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