Paradigm shift from tubal ligation to opportunistic salpingectomy at cesarean delivery in the United States.

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Opportunistic salpingectomy is now recommended at the time of routine gynecologic surgery to reduce the risk of future ovarian cancer, and performance of opportunistic salpingectomy has increased markedly at the […]

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Prenatal alcohol consumption and placental outcomes: A systematic review and meta-analysis of clinical studies.

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A systematic review was conducted to determine placental outcomes following prenatal alcohol exposure (PAE) in women.The search terms “maternal OR prenatal OR pregnant OR periconception” AND “placenta” AND “alcohol OR […]

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Placental extracellular vesicles-associated miRNA-519c mediates endotoxin adaptation in pregnancy.

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Pregnancy represents a unique challenge for the maternal-fetal immune interface, requiring a balance between immunosuppression, which is essential for the maintenance of a semi-allogeneic fetus, and pro-inflammatory host defense to […]

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Research Biopsies in patients with gynecologic cancers: patient-reported outcomes, perceptions and preferences.

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Despite the growing integration of mandatory biopsies for correlative endpoints within oncology clinical trials, there is sparse data on patient-reported outcomes, perceptions and preferences.(s): The aim of this study was […]

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Uptake and timing of risk-reducing salpingo-oophorectomy among patients with BRCA1/2 mutations.

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In women with BRCA mutations, risk-reducing bilateral salpingo-oophorectomy (RRSO) has been shown to decrease gynecologic cancer-specific and overall mortality. The National Comprehensive Cancer Network (NCCN) recommends that patients with BRCA […]

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Addition of oral iron bisglycinate to intravenous iron sucrose for the treatment of postpartum anemia – randomized controlled trial.

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Studies which have compared the effectiveness of oral versus intravenous iron supplements to treat postpartum anemia have shown mixed results. The superiority of one mode of treatment versus the other […]

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Society for Maternal-Fetal Medicine (SMFM) Consult Series #57: Evaluation and Management of Isolated Soft Ultrasound Markers for Aneuploidy in the Second Trimester.

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Soft markers were originally introduced to prenatal ultrasonography to improve the detection of trisomy 21 over that achievable with age-based and serum screening strategies. As prenatal genetic screening strategies have […]

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Effectiveness of uterine tamponade devices for refractory postpartum haemorrhage after vaginal birth: a systematic review.

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To evaluate uterine tamponade devices’ effectiveness for atonic refractory postpartum haemorrhage (PPH) after vaginal birth and the effect of including them in institutional protocols.PubMed, EMBASE, CINAHL, LILACS, POPLINE, from inception […]

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Subgroups of failure after surgery for pelvic organ prolapse and associations with quality of life outcomes: a longitudinal cluster analysis.

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Treatment outcomes after pelvic organ prolapse (POP) surgery are often presented as dichotomous ‘success or failure’ based upon anatomic and symptom criteria. However, clinical experience suggests some women with outcome […]

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Amniotic fluid microRNA profiles in twin-twin transfusion syndrome with and without severe recipient cardiomyopathy.

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Twin-twin transfusion syndrome presents many challenges for clinicians, and the optimal means of identifying which pregnancies will benefit most from intervention is controversial. There is currently no clinically available biomarker […]

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Correlation of surgical case volume and fellowship training with performance on simulated procedural tasks.

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High-volume and fellowship-trained surgeons have superior outcomes. However, in gynecology, a large proportion of cases are performed by low-volume surgeons. Simulation has been shown to be useful in assessing surgical […]

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Incidence, prevalence and trends in endometriosis diagnosis: A United States population-based study from 2006-2015.

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Accurate estimates of incidence and prevalence of endometriosis among non-selected cohorts are lacking in the US and prior reports have produced varying results.To define endometriosis incidence and prevalence in a […]

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Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study.

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To assess the association between vaginal microbiome (VMB) composition and recurrent early spontaneous preterm birth (sPTB)/preterm prelabour rupture of membranes (PPROM).Nested case-control study.UK tertiary referral hospital.High-risk women with previous sPTB/PPROM […]

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Women’s experiences of a telemedicine abortion service (up to 12 weeks) implemented during the coronavirus (COVID-19) pandemic: A qualitative evaluation.

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To explore the experiences of women in Scotland who accessed medical abortion at home up to 12 weeks gestation, delivered via a telemedicine abortion service implemented in response to the […]

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Evaluation of the RCOG guideline in the prediction of small for gestational age neonates and comparison with the competing risks model.

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To examine the predictive performance for small for gestational age (SGA) neonates of the relevant guideline by the Royal College of Obstetricians and Gynecologists (RCOG), and to compare the performance […]

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Anti-Müllerian hormone levels among contraceptive users: evidence from a cross-sectional cohort of 27,125 individuals.

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Anti-Müllerian Hormone has become the clinical biomarker-based standard to assess ovarian reserve. As anti-Müllerian hormone testing becomes more common, more individuals are seeking to interpret values obtained while using contraceptives. […]

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Chronic histiocytic intervillositis: manifestation of placental alloantibody-mediated rejection.

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Chronic histiocytic intervillositis (chronic intervillositis) is defined by a diffuse infiltration of monocytes into the intervillous space that often results in poor obstetrical outcomes, including recurrent intrauterine growth restriction, miscarriage […]

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Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia.

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Observational studies have shown that fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased survival among infants with severe pulmonary hypoplasia due to isolated congenital diaphragmatic hernia on the […]

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Defining Mechanisms of Recurrence Following Apical Prolapse Repair Based on Imaging Criteria.

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Prolapse recurrence after transvaginal surgical repair is common; however, its mechanisms are ill-defined. A thorough understanding of how and why prolapse repairs fail is needed to address their high rate […]

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Sexual Function After Pelvic Organ Prolapse Surgery: A Systematic Review Comparing Different Approaches to Pelvic Floor Repair.

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Women consider preservation of sexual activity and improvement of sexual function as important goals following pelvic organ prolapse (POP) surgery. The aim of this systematic review is to compare sexual […]

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