It is unclear whether the suggested link between COVID-19 during pregnancy and preeclampsia is an independent association or if these are caused by common risk factors.This study aimed to quantify […]» Read more
Controversy exists regarding the threshold of recipient twin polyhydramnios required to diagnose twin-twin transfusion syndrome at a gestational age ≥ 20 weeks. One criterion set (Quintero staging) requires the amniotic […]» Read more
Paradigm shift from tubal ligation to opportunistic salpingectomy at cesarean delivery in the United States.
Opportunistic salpingectomy is now recommended at the time of routine gynecologic surgery to reduce the risk of future ovarian cancer, and performance of opportunistic salpingectomy has increased markedly at the […]» Read more
Prenatal alcohol consumption and placental outcomes: A systematic review and meta-analysis of clinical studies.
A systematic review was conducted to determine placental outcomes following prenatal alcohol exposure (PAE) in women.The search terms “maternal OR prenatal OR pregnant OR periconception” AND “placenta” AND “alcohol OR […]» Read more
Pregnancy represents a unique challenge for the maternal-fetal immune interface, requiring a balance between immunosuppression, which is essential for the maintenance of a semi-allogeneic fetus, and pro-inflammatory host defense to […]» Read more
Umbilical cord prolapse is an unpredictable obstetric emergency with an incidence ranging from 1 to 6 per 1000 pregnancies. It is associated with high perinatal mortality, ranging from 23-27%, in […]» Read more
Stillbirths occur 10 to 20 times more frequently in low-income settings compared to high-income settings. We created a methodology to define the proportion of stillbirths that are potentially preventable in […]» Read more
Research Biopsies in patients with gynecologic cancers: patient-reported outcomes, perceptions and preferences.
Despite the growing integration of mandatory biopsies for correlative endpoints within oncology clinical trials, there is sparse data on patient-reported outcomes, perceptions and preferences.(s): The aim of this study was […]» Read more
In women with BRCA mutations, risk-reducing bilateral salpingo-oophorectomy (RRSO) has been shown to decrease gynecologic cancer-specific and overall mortality. The National Comprehensive Cancer Network (NCCN) recommends that patients with BRCA […]» Read more
Addition of oral iron bisglycinate to intravenous iron sucrose for the treatment of postpartum anemia – randomized controlled trial.
Studies which have compared the effectiveness of oral versus intravenous iron supplements to treat postpartum anemia have shown mixed results. The superiority of one mode of treatment versus the other […]» Read more
Society for Maternal-Fetal Medicine (SMFM) Consult Series #57: Evaluation and Management of Isolated Soft Ultrasound Markers for Aneuploidy in the Second Trimester.
Soft markers were originally introduced to prenatal ultrasonography to improve the detection of trisomy 21 over that achievable with age-based and serum screening strategies. As prenatal genetic screening strategies have […]» Read more
Improving maternal and newborn health outcomes has been a key focus of the Millennium Development Goals and Sustainable Development Goals. To meet these goals, access to and provision of high-quality […]» Read more
For many years, uterine balloon tamponade (UBT) has been used to treat severe postpartum haemorrhage (PPH), despite a lack of randomised trials to demonstrate its effectiveness. With commercial devices being […]» Read more
Effectiveness of uterine tamponade devices for refractory postpartum haemorrhage after vaginal birth: a systematic review.
To evaluate uterine tamponade devices’ effectiveness for atonic refractory postpartum haemorrhage (PPH) after vaginal birth and the effect of including them in institutional protocols.PubMed, EMBASE, CINAHL, LILACS, POPLINE, from inception […]» Read more
Subgroups of failure after surgery for pelvic organ prolapse and associations with quality of life outcomes: a longitudinal cluster analysis.
Treatment outcomes after pelvic organ prolapse (POP) surgery are often presented as dichotomous ‘success or failure’ based upon anatomic and symptom criteria. However, clinical experience suggests some women with outcome […]» Read more
Amniotic fluid microRNA profiles in twin-twin transfusion syndrome with and without severe recipient cardiomyopathy.
Twin-twin transfusion syndrome presents many challenges for clinicians, and the optimal means of identifying which pregnancies will benefit most from intervention is controversial. There is currently no clinically available biomarker […]» Read more
Correlation of surgical case volume and fellowship training with performance on simulated procedural tasks.
High-volume and fellowship-trained surgeons have superior outcomes. However, in gynecology, a large proportion of cases are performed by low-volume surgeons. Simulation has been shown to be useful in assessing surgical […]» Read more
Incidence, prevalence and trends in endometriosis diagnosis: A United States population-based study from 2006-2015.
Accurate estimates of incidence and prevalence of endometriosis among non-selected cohorts are lacking in the US and prior reports have produced varying results.To define endometriosis incidence and prevalence in a […]» Read more
Dynamic Esophageal Patency Assessment: An effective method for prenatally diagnosing esophageal atresia.
Esophageal atresia is a major anomaly with a low prenatal detection rate. We propose a sonographic method termed Dynamic Esophageal Patency Assessment (DEPA). The aim of the study was to […]» Read more
Anglophone narratives of Semmelweis’s discovery of the cause and prophylaxis of childbed (puerperal) fever are based on a deficient historical record because important information about what happened to Semmelweis in […]» Read more
Uterine fibroids, the most common type of tumor among women of reproductive age are often associated with symptoms and a reduced quality of life (Stewart et al. BJOG 2017;124:1501-12). Hysterectomy […]» Read more
Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study.
To assess the association between vaginal microbiome (VMB) composition and recurrent early spontaneous preterm birth (sPTB)/preterm prelabour rupture of membranes (PPROM).Nested case-control study.UK tertiary referral hospital.High-risk women with previous sPTB/PPROM […]» Read more
Women’s experiences of a telemedicine abortion service (up to 12 weeks) implemented during the coronavirus (COVID-19) pandemic: A qualitative evaluation.
To explore the experiences of women in Scotland who accessed medical abortion at home up to 12 weeks gestation, delivered via a telemedicine abortion service implemented in response to the […]» Read more
Evaluation of the RCOG guideline in the prediction of small for gestational age neonates and comparison with the competing risks model.
To examine the predictive performance for small for gestational age (SGA) neonates of the relevant guideline by the Royal College of Obstetricians and Gynecologists (RCOG), and to compare the performance […]» Read more
Anti-Müllerian hormone levels among contraceptive users: evidence from a cross-sectional cohort of 27,125 individuals.
Anti-Müllerian Hormone has become the clinical biomarker-based standard to assess ovarian reserve. As anti-Müllerian hormone testing becomes more common, more individuals are seeking to interpret values obtained while using contraceptives. […]» Read more
Chronic histiocytic intervillositis (chronic intervillositis) is defined by a diffuse infiltration of monocytes into the intervillous space that often results in poor obstetrical outcomes, including recurrent intrauterine growth restriction, miscarriage […]» Read more
Association of Maternal Influenza Vaccination During Pregnancy With Early Childhood Health Outcomes.
Seasonal influenza vaccination in pregnancy can reduce influenza illness among pregnant women and newborns. Evidence is limited on whether seasonal influenza vaccination in pregnancy is associated with adverse childhood health […]» Read more
Observational studies have shown that fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased survival among infants with severe pulmonary hypoplasia due to isolated congenital diaphragmatic hernia on the […]» Read more
Prolapse recurrence after transvaginal surgical repair is common; however, its mechanisms are ill-defined. A thorough understanding of how and why prolapse repairs fail is needed to address their high rate […]» Read more
Sexual Function After Pelvic Organ Prolapse Surgery: A Systematic Review Comparing Different Approaches to Pelvic Floor Repair.
Women consider preservation of sexual activity and improvement of sexual function as important goals following pelvic organ prolapse (POP) surgery. The aim of this systematic review is to compare sexual […]» Read more