Machine learning classifier to identify clinical and radiological features relevant to disability progression in multiple sclerosis.

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To evaluate the accuracy of a data-driven approach, such as machine learning classification, in predicting disability progression in MS.We analyzed structural brain images of 163 subjects diagnosed with MS acquired […]

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Association of intracranial vessel wall enhancement and cerebral hemorrhage in moyamoya disease: a high-resolution magnetic resonance imaging study.

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This study aimed to investigate the enhancement characteristics of vessel wall in patients with moyamoya disease (MMD) using 3D high-resolution magnetic resonance (MR) imaging and their relationship with initial and […]

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Baseline cognitive profile is closely associated with long-term motor prognosis in newly diagnosed Parkinson’s disease.

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To investigate the association between cognitive function at baseline and the progression of motor disability in Parkinson’s disease (PD).We consecutively enrolled 257 drug-naïve patients with early-stage PD (follow-up > 2 years) who underwent […]

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Paraneoplastic vs. non-paraneoplastic anti-Hu associated dysmotility: a case series and literature review.

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This work aimed to report the demographic and clinical characteristics of two new cases with non-paraneoplastic anti-Hu-associated gut motility impairment, and perform a thorough revision covering anti-Hu-associated paraneoplastic (PGID) and […]

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Cellular immunology of relapsing multiple sclerosis: interactions, checks, and balances.

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Novel insights from basic and translational studies are reshaping concepts of the immunopathogenesis of multiple sclerosis and understanding of the different inflammatory responses throughout the disease course. Previously, the cellular […]

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Intraluminal carotid thrombosis and acute ischemic stroke associated with COVID-19.

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COVID-19 (Coronavirus disease 2019) caused by SARS-CoV-2 has a diverse constellation of neurological manifestations that include encephalopathy, stroke, Guillain-Barré syndrome, myelitis, and encephalitis. Intraluminal carotid thrombi (ILT) are infrequent lesions […]

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Iron-sensitive magnetic resonance imaging in Parkinson’s disease: a systematic review and meta-analysis.

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To evaluate the diagnostic performance of iron-sensitive sequences targeting the substantia nigra for distinguishing patients with Parkinson’s disease from control participants and to identify factors causing heterogeneity.A systematic literature search […]

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Defining functional brain networks underlying obsessive-compulsive disorder (OCD) using treatment-induced neuroimaging changes: a systematic review of the literature.

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Approximately 2%-3% of the population suffers from obsessive-compulsive disorder (OCD). Several brain regions have been implicated in the pathophysiology of OCD, but their various contributions remain unclear. We examined changes […]

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Bilateral staged magnetic resonance-guided focused ultrasound thalamotomy for the treatment of essential tremor: a case series study.

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Unilateral magnetic resonance-guided focused ultrasound (FUS) thalamotomy is efficacious for the treatment of medically refractory essential tremor (ET). Viability of bilateral FUS ablation is unexplored.Patients diagnosed with medically refractory ET […]

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Ischaemic stroke on anticoagulation therapy and early recurrence in acute cardioembolic stroke: the IAC study.

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A subset of ischaemic stroke patients with atrial fibrillation (AF) have ischaemic stroke despite anticoagulation. We sought to determine the association between prestroke anticoagulant therapy and recurrent ischaemic events and […]

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Memory enhancement by multidomain group cognitive training in patients with Parkinson’s disease and mild cognitive impairment: long-term effects of a multicenter randomized controlled trial.

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Meta-analyses indicate positive effects of cognitive training (CT) in patients with Parkinson’s disease (PD), however, most previous studies had small sample sizes and did not evaluate long-term follow-up. Therefore, a […]

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