Once-Daily Vibegron 75 mg for Overactive Bladder: Long-Term Safety and Efficacy From a Double-Blind Extension Study of the International Phase 3 Trial (EMPOWUR).

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The long-term safety, tolerability, and efficacy of vibegron in adults with overactive bladder were evaluated in the 40-week phase 3 EMPOWUR extension study.Patients who completed 12 weeks of once-daily vibegron […]

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The Modified Prone Jack-knife Position for the Excision of Female Urethral Diverticula.

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Female urethral diverticula (UD) are an uncommon and often overlooked aetiology in women presenting with lower urinary tract symptoms, urethral pain, and recurrent urinary tract infection. With increasing awareness, appropriate […]

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Systematic Review and Meta-Analysis of the Association Between Vitamin D Status and Lower Urinary Tract Symptoms.

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Cumulative studies have shown that vitamin D may be associated with lower urinary tract symptoms, but the findings have been inconsistent. The aim of this study was to systematically evaluate […]

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Hood Technique for Robotic Radical Prostatectomy-Preserving Periurethral Anatomical Structures in the Space of Retzius and Sparing the Pouch of Douglas, Enabling Early Return of Continence Without Compromising Surgical Margin Rates.

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A common side effect following radical prostatectomy is urinary incontinence. Here, we describe a novel surgical technique to reduce postoperative urinary incontinence and facilitate early return of continence.To describe the […]

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Racial differences in urinary incontinence prevalence, overactive bladder and associated bother among men: The Multi-Ethnic Study of Atherosclerosis.

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To examine the association of race/ethnicity with urinary incontinence subtypes and overactive bladder and associated bother in older men.This cross-sectional analysis utilized data from Multi-Ethnic Study of Atherosclerosis, an observational […]

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Pregnancy and Delivery in Women with Lower Urinary Tract Reconstruction: A National Multicenter Retrospective Study.

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Management of pregnancy and delivery in women with lower urinary tract reconstruction is challenging and the currently available literature is insufficient to guide clinical practice. The purpose of this study […]

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Assessing the Quality of Surgical Care for Clinically Localized Prostate Cancer: Results from the CEASAR Study.

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Prior studies suggest that nationally endorsed quality measures for prostate cancer care are not linked closely with outcomes. Using a prospective, population-based cohort, we sought to measure clinically relevant variation […]

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Retzius-sparing Robot-assisted Radical Prostatectomy Leads to Durable Improvement in Urinary Function and Quality of Life Versus Standard Robot-assisted Radical Prostatectomy Without Compromise on Oncologic Efficacy: Single-surgeon Series and Step-by-step Guide.

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Retzius-sparing robot-assisted radical prostatectomy (RS-RARP) has been shown to improve continence. However, questions remain regarding feasibility and generalizability of technique and outcomes.To compare the outcomes of 140 consecutive standard robot-assisted […]

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Grading Severity and Bother Using the IPSS and ICIQ-MLUTS Scores in Men Seeking Lower Urinary Tract Symptoms Therapy.

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To establish severity banding ranges, bother assessment and key item content in principal patient reported outcomes measures (PROMs) in men seeking therapy for lower urinary tract symptoms (LUTS).Data for International […]

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Development and Internal Validation of a Web-based Tool to Predict Sexual, Urinary, and Bowel Function Longitudinally After Radiation Therapy, Surgery, or Observation.

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Shared decision making to guide treatment of localized prostate cancer requires delivery of the anticipated quality of life (QOL) outcomes of contemporary treatment options (including radical prostatectomy [RP], intensity-modulated radiation […]

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Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer.

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Understanding adverse effects of contemporary treatment approaches for men with favorable-risk and unfavorable-risk localized prostate cancer could inform treatment selection.To compare functional outcomes associated with prostate cancer treatments over 5 […]

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Women’s Experience with Stress Urinary Incontinence: Insights from Social Media Analytics.

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To capture the complete patient experience, knowledge and perceptions among women with stress urinary incontinence (SUI) by conducting a large-scale digital ethnographic analysis of anonymous online posts.Online posts were identified […]

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Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received.

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The ProtecT trial reported intention-to-treat analysis of men with localised prostate cancer randomly allocated to active monitoring (AM), radical prostatectomy, and external beam radiotherapy.To report outcomes according to treatment received […]

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Cost Effectiveness of Sacral Neuromodulation Versus OnabotulinumtoxinA for Refractory Urgency Urinary Incontinence: Results of the ROSETTA Randomized Trial.

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Sacral neuromodulation and intradetrusor injection of onabotulinumtoxinA are therapies for refractory urgency-urinary incontinence. Sacral neuromodulation involves surgical implant of a device that can last 4-6 years, while onabotulinumtoxinA involves serial […]

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Utilization of Surgery for Post-prostatectomy Incontinence.

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Abstract: Stress urinary incontinence (SUI) following radical prostatectomy (RP) is common and potentially debilitating. For men who fail conservative measures to treat post-prostatectomy incontinence (PPI), surgical therapy with either a […]

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