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Hypothyroidism Research Articles:
A selection of the latest clinical research articles relating to Hypothyroidism. Articles are sourced from leading medical journals helping you keep up to date quickly and easily. You can bookmark the most relevant articles for future reference by creating a free account today.
Both hyperthyroidism and hypothyroidism can have adverse effects in pregnancy. The most common causes of thyrotoxicosis in pregnancy are gestational transient thyrotoxicosis and Graves’ disease. It is important to distinguish […]
» Read moreThyroid cancer tends to be diagnosed at a younger age (median age 51 years) compared with most other malignancies (such as breast cancer [62 years] or lung cancer [71 years]). […]
» Read moreMultimorbidity impacts quality of life. We constructed hypothyroidism comorbidity networks to identify positive and negative associations with other prevalent diseases.We analyzed data of 285,342 patients with hypothyroidism from 3,135,948 adults […]
» Read moreThyroid hormone is essential for optimal human neurodevelopment and may modify the risk of attention-deficit hyperactivity disorder (ADHD). However, the brain structures involved are unknown and it is unclear if […]
» Read moreThyroid hormones play an important role in the metabolic homeostasis and higher levels have been associated with cardiometabolic risk.To examine the association of cardiometabolic risk factors with TSH levels in […]
» Read moreEarly treatment of primary congenital hypothyroidism (CH) prevents irreversible brain damage. Contrary to primary CH, outcome studies on central CH are scarce. Most central CH patients have multiple pituitary hormone […]
» Read moreHypothyroidism is associated with reversible decline in kidney function as measured by estimated glomerular filtration rate (eGFR). eGFR and proteinuria are most important markers for clinical assessment of kidney function. […]
» Read moreProteinuria can cause or exacerbate hypothyroidism, possibly due to urinary loss of protein-bound thyroid hormone. However, the precise relationship between proteinuria and hypothyroidism remains unclear.Determine the prevalence of hypothyroidism in […]
» Read moreDevelopment of the typical growth phenotype of juvenile acquired hypothyroidism (JHT), the faltering linear growth with increasing weight, has not been thoroughly characterized.To describe longitudinal growth pattern in children developing […]
» Read moreWe do not fully understand how hypercortisolism causes central hypothyroidism or what factors influence recovery of the hypothalamic-pituitary-thyroid axis. We evaluated thyroid function during and after cure of Cushing’s syndrome […]
» Read moreAmiodarone is a class III antiarrhythmic drug containing 37% iodine by weight, with a structure similar to that of thyroid hormones. Deiodination of amiodarone releases large amounts of iodine that […]
» Read moreThe rare syndrome of hypoparathyroidism, retardation, and dysmorphism (OMIM #241410) is caused by the mutated tubulin chaperone E (TBCE) gene. This gene encodes a critical protein in the microtubule assembly […]
» Read moreAnalysis of a two-screen program for congenital hypothyroidism (CH) using differential blood TSH (bTSH) cutoffs of 10 mU/L at first screening (all infants) and 5 mU/L at second screening (selected […]
» Read moreWeight gain is a major driver of dissatisfaction and decreased quality of life in patients with hypothyroidism. Data on the changes in body weight following thyroidectomy are conflicting.To perform a […]
» Read moreBenefits of thyroid hormone therapy on mortality in adults with subclinical hypothyroidism remain undetermined.To summarize the impact of thyroid hormone therapy on mortality in adults with subclinical hypothyroidism.PubMed, Embase, Scopus, […]
» Read moreInactivating variants of TSH receptor (TSHR) cause congenital hypothyroidism. More than 60 such variants have been reported so far, most of which were located in the extracellular or transmembrane domain.We […]
» Read moreAlthough subclinical hypothyroidism (SCH) is a common clinical entity and carries independent risk for incident heart failure (HF), its possible association with subclinical cardiac dysfunction is unclear. Left ventricular global […]
» Read moreThyroid dyshormonogenesis is a heterogeneous group of hereditary diseases produced by a total/partial blockage of the biochemical processes of thyroid-hormone synthesis and secretion. PAX8 is essential for thyroid morphogenesis and […]
» Read moreDissatisfaction with treatment and impaired quality of life (QOL) are reported amongst people with treated hypothyroidism. We aimed to gain insight into this.We conducted an online survey of individuals with […]
» Read moreHyperthyroidism is associated with low levels of cholesterol and triglycerides, and hypothyroidism is associated with hypercholesterolemia and hypertriglyceridemia.The aim of this systematic review was to investigate the impact of therapy […]
» Read moreThyroid function is clinically evaluated by determination of circulating concentrations of TSH and fT4. However, a tissue-specific effector substrate of thyroid function is lacking. Energy-rich phosphorus-containing metabolites (PM) and phospholipids […]
» Read morePrader-Willi syndrome (PWS) is a complex hypothalamic disorder, combining hyperphagia, hypotonia, intellectual disability and pituitary hormone deficiencies. Annual mortality of patients with PWS is high (3%). In half of the […]
» Read moreAbnormalities in the hypothalamic-pituitary-thyroid (HPT) axis have been implicated in Prader-Willi syndrome (PWS); however, limited information is currently available on age-dependent alterations in the HPT axis. We herein investigated age-dependent […]
» Read moreLevothyroxine treatment for hypothyroidism in early pregnancy has inconsistent outcomes.This study evaluated children’s cognitive function to ascertain the impact of preconception maternal hypothyroidism treatment on fetal neurodevelopment.Prospective cohort study.A single-center […]
» Read morePAX8 is a transcription factor required for thyroid development, and its mutation causes congenital hypothyroidism (CH). More than 20 experimentally verified loss-of-function PAX8 mutations have been described, and all but […]
» Read morePrevious studies suggested a potential link of maternal thyroid dysfunction with adverse neurocognitive outcomes and impaired development of internal organs in offspring.To review the association between maternal thyroid dysfunction and […]
» Read moreThyroid hormones are crucial developmental factors and thyroid disease in pregnant women is a concern. Overweight and obesity are also important health concerns, and we hypothesized that in utero exposure […]
» Read moreSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 18 million people worldwide and the pandemic is still spreading. After the first case we reported, we observed 4 […]
» Read moreSevere hypothyroidism has profound effects on lipoprotein metabolism including high-density lipoprotein (HDL) cholesterol elevations but effects on HDL function metrics are unknown.To determine the impact of severe short-term hypothyroidism on […]
» Read moreThyroid hormones play a key role in modulating myocardial contractility. Subclinical hypothyroidism in patients with acute myocardial infarction is associated with poor prognosis.To evaluate the effect of levothyroxine treatment on […]
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