Globally, nearly 10% of the population has chronic kidney disease (CKD), defined as a glomerular filtration rate less than 60 mL/min/1.73 m2 and/or a urinary albumin to creatinine ratio greater than 30 mg/g […]» Read more
This study describes the influence of sex and disease phenotype on the occurrence of cardiac events in Fabry disease (FD).Cardiac events from birth to last visit (median age 50 years) […]» Read more
We evaluated the sex differences in 6-month heart failure (HF) hospitalisation risk in acute myocardial infarction (AMI) survivors.For this retrospective cohort analysis, adult survivors of an AMI between January and […]» Read more
Effect of long-term beta-blocker treatment following myocardial infarction among stable, optimally treated patients without heart failure in the reperfusion era: a Danish, nationwide cohort study.
Listen to the audio abstract of this contribution at https://doi.org/10.1093/eurheartj/ehaa1058.We aimed to investigate the long-term cardio-protective effect associated with beta-blocker (BB) treatment in stable, optimally treated myocardial infarction (MI) patients […]» Read more
Empagliflozin and health-related quality of life outcomes in patients with heart failure with reduced ejection fraction: the EMPEROR-Reduced trial.
In this secondary analysis of the EMPEROR-Reduced trial, we sought to evaluate whether the benefits of empagliflozin varied by baseline health status and how empagliflozin impacted patient-reported outcomes in patients […]» Read more
Comparison of the Efficacy and Safety of Sacubitril/Valsartan versus Ramipril in Patients with ST-Segment Elevation Myocardial Infarction.
The role of sacubitril/valsartan in patient with heart failure (HF) is established. Whether sacubitril/valsartan plays a role in improving outcomes in patients after ST-segment elevation myocardial infarction (STEMI) is unknown. […]» Read more
Comparison of Survival in Patients with Clinically Significant Tricuspid Regurgitation with and without Heart Failure (From the Optum Integrated File).
This study aimed to quantify survival rates for patients with Tricuspid Regurgitation (TR) using real-world data. Several clinical conditions are associated with tricuspid regurgitation (TR), including heart failure (HF), other […]» Read more
Effectiveness and Safety of Extracorporeal Shockwave Myocardial Revascularization in Patients with Refractory Angina Pectoris and Heart Failure.
Extracorporeal shockwave myocardial revascularization (ESMR) is a therapy for refractory angina pectoris. Our aim was to assess the efficacy and safety of ESMR in the management of patients with stable […]» Read more
Transcatheter Aortic Valve Implantation in Patients with Severe Aortic Stenosis Hospitalized with Acute Heart Failure.
Optimal timing and outcomes of transcatheter aortic valve implantation (TAVI) in patients presenting with acute heart failure (AHF) remain unclear. In this consecutive cohort of 1547 patients with severe aortic […]» Read more
Prognostic value of peak stress cardiac power in patients with normal ejection fraction undergoing exercise stress echocardiography.
Cardiac power is a measure of cardiac performance that incorporates both pressure and flow components. Prior studies have shown that cardiac power predicts outcomes in patients with reduced left ventricular […]» Read more
Comparison of Outcomes of Beta-Blocker Therapy after Acute Myocardial Infarction in Patients without Heart Failure or Left Ventricular Systolic Dysfunction (From the Acute Coronary Syndromes Israeli Survey [ACSIS]).
The contemporary benefit of routine beta-blocker therapy following myocardial infraction in the absence of heart failure or left ventricular systolic dysfunction (LVSD) is unclear. We investigated the impact of beta-blockers […]» Read more
Prognostic Value of Pre-operative Atrial Fibrillation in Patients with Secondary Mitral Regurgitation Undergoing MitraClip Implantation.
Limited data are available regarding the independent prognostic role of pre-operative AF after transcatheter mitral valve repair with MitraClip. We sought to evaluate the impact of pre-operative atrial fibrillation (AF) […]» Read more
Alternative Echocardiographic Algorithm for Left Ventricular Filling Pressure in Patients with Heart Failure with Preserved Ejection Fraction.
The American Society of Echocardiography / the European Association of Cardiovascular Imaging recommend a conventional algorithm for estimating left ventricular (LV) filling pressure in heart failure. However, several patients are […]» Read more
Influence of Chronic Obstructive Pulmonary Disease on Atrial Mechanics by Speckle Tracking Echocardiography in Patients with Atrial Fibrillation.
The present study aimed to examine differences in left- and right atrial characteristics between atrial fibrillation (AF) patients with and without chronic obstructive pulmonary disease (COPD). For this, 420 patients […]» Read more
Systolic Blood Pressure and Risk for Ventricular Arrhythmia in Patients with an Implantable Cardioverter Defibrillator.
Low systolic blood pressure (SBP) was previously suggested to be a marker for heart failure and mortality in patients with low left ventricular (LV) ejection fraction (EF). We aimed to […]» Read more
Elevated levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) are associated with heart failure-related death in hypertrophic cardiomyopathy (HCM), but the relationship between NT-proBNP level and sudden cardiac death (SCD) in […]» Read more
Revisiting heart failure assessment based on objective measures in NYHA functional classes I and II.
New York Heart Association (NYHA) functional class plays a central role in heart failure (HF) assessment but might be unreliable in mild presentations. We compared objective measures of HF functional […]» Read more
Limited contemporary data exist regarding outcomes and resource use among adults with congenital heart disease and heart failure (ACHD-HF). This study compared outcomes, emergency department (ED) and hospital resource use, […]» Read more
Low-density lipoprotein cholesterol reduction and statin intensity in myocardial infarction patients and major adverse outcomes: a Swedish nationwide cohort study.
Clinical trials have demonstrated that a reduction in low-density lipoprotein cholesterol (LDL-C) reduces cardiovascular (CV) events. This has, however, not yet been shown in a real-world setting. We aimed to […]» Read more
Necrotizing coronary vasculitis (NCV) is a rare entity usually associated to myocarditis which incidence, cause, and response to therapy is unreported.Among 1916 patients with biopsy-proven myocarditis, 30 had NCV. Endomyocardial […]» Read more
Effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction, with and without type 2 diabetes.
The EMPERIAL (Effect of EMPagliflozin on ExeRcise ability and HF symptoms In patients with chronic heArt faiLure) trials evaluated the effects of empagliflozin on exercise ability and patient-reported outcomes in […]» Read more
Cardiac involvement in amyloidosis is associated with a poor prognosis. Data on the burden of arrhythmias in patients with cardiac amyloidosis (CA) during hospitalization is lacking. We identified the burden […]» Read more
Diagnostic and Prognostic Value of Several Color Doppler Jet Grading Methods in Patients with Mitral Regurgitation.
Color Doppler is a widely used ultrasound imaging method for assessing mitral regurgitation (MR) in clinical practice. Nevertheless, color Doppler-based grading of the MR jet has been rarely considered in […]» Read more
Two-dimensional (2D) longitudinal strain (LS) predicts cardiac events in aortic stenosis (AS). However, it requires manual editing, which affects its accuracy and reliability. We investigated whether left ventricular (LV), left […]» Read more
Vegetarians, fish, poultry, and meat-eaters: who has higher risk of cardiovascular disease incidence and mortality? A prospective study from UK Biobank.
To compare the incidence and mortality risk for cardiovascular diseases (CVD) [CVD and also ischaemic heart disease (IHD), myocardial infarction (MI), stroke, and heart failure (HF)] among people with different […]» Read more
Epidemiological evidence on the relationship between lipid profile and cardiovascular disease (CVD) events in young adults remains insufficient. Thus, we sought to explore the association of lipid profile with subsequent […]» Read more
The risk of cardiac events in patients receiving immune checkpoint inhibitors: a nationwide Danish study.
The study aimed to estimate the risk of cardiac events in immune checkpoint inhibitor (ICI)-treated patients with lung cancer or malignant melanoma.The study included consecutive patients with lung cancer or […]» Read more
Meta-Analysis of the Usefulness of Catheter Ablation of Atrial Fibrillation in Patients with Heart Failure with Preserved Ejection Fraction.
Catheter ablation improves clinical outcomes in atrial fibrillation (AF) patients with heart failure (HF) with reduced ejection fraction (HFrEF). However, the role of catheter ablation in HF with a preserved […]» Read more
Outcomes with Ultrafiltration among Hospitalized Patients with Acute Heart Failure (From the National Inpatient Sample).
Acute heart failure (HF) management is a complex and often involves a delicate balance of both cardiac and renal systems. While pharmacologic diuresis is a mainstay of the pharmacologic management […]» Read more
Treatment of Patients with Recurrent Coronary In-Stent Restenosis with Failed Intravascular Brachytherapy.
Intravascular brachytherapy (VBT) is an effective and safe treatment option for recurrent drug-eluting stent (DES) in-stent restenosis (ISR). However, the optimal therapy for patients with failed VBT is not well-defined. […]» Read more