Chronic kidney disease detection, staging and treatment in cardiovascular disease prevention.

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Globally, nearly 10% of the population has chronic kidney disease (CKD), defined as a glomerular filtration rate less than 60 mL/min/1.73 m2 and/or a urinary albumin to creatinine ratio greater than 30 mg/g […]

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Influence of sex and phenotype on cardiac outcomes in patients with Fabry disease.

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This study describes the influence of sex and disease phenotype on the occurrence of cardiac events in Fabry disease (FD).Cardiac events from birth to last visit (median age 50 years) […]

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Sex differences in heart failure hospitalisation risk following acute myocardial infarction.

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We evaluated the sex differences in 6-month heart failure (HF) hospitalisation risk in acute myocardial infarction (AMI) survivors.For this retrospective cohort analysis, adult survivors of an AMI between January and […]

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Effect of long-term beta-blocker treatment following myocardial infarction among stable, optimally treated patients without heart failure in the reperfusion era: a Danish, nationwide cohort study.

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Listen to the audio abstract of this contribution at https://doi.org/10.1093/eurheartj/ehaa1058.We aimed to investigate the long-term cardio-protective effect associated with beta-blocker (BB) treatment in stable, optimally treated myocardial infarction (MI) patients […]

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Empagliflozin and health-related quality of life outcomes in patients with heart failure with reduced ejection fraction: the EMPEROR-Reduced trial.

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In this secondary analysis of the EMPEROR-Reduced trial, we sought to evaluate whether the benefits of empagliflozin varied by baseline health status and how empagliflozin impacted patient-reported outcomes in patients […]

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Comparison of the Efficacy and Safety of Sacubitril/Valsartan versus Ramipril in Patients with ST-Segment Elevation Myocardial Infarction.

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The role of sacubitril/valsartan in patient with heart failure (HF) is established. Whether sacubitril/valsartan plays a role in improving outcomes in patients after ST-segment elevation myocardial infarction (STEMI) is unknown. […]

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Comparison of Survival in Patients with Clinically Significant Tricuspid Regurgitation with and without Heart Failure (From the Optum Integrated File).

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This study aimed to quantify survival rates for patients with Tricuspid Regurgitation (TR) using real-world data. Several clinical conditions are associated with tricuspid regurgitation (TR), including heart failure (HF), other […]

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Effectiveness and Safety of Extracorporeal Shockwave Myocardial Revascularization in Patients with Refractory Angina Pectoris and Heart Failure.

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Extracorporeal shockwave myocardial revascularization (ESMR) is a therapy for refractory angina pectoris. Our aim was to assess the efficacy and safety of ESMR in the management of patients with stable […]

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Transcatheter Aortic Valve Implantation in Patients with Severe Aortic Stenosis Hospitalized with Acute Heart Failure.

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Optimal timing and outcomes of transcatheter aortic valve implantation (TAVI) in patients presenting with acute heart failure (AHF) remain unclear. In this consecutive cohort of 1547 patients with severe aortic […]

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Prognostic value of peak stress cardiac power in patients with normal ejection fraction undergoing exercise stress echocardiography.

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Cardiac power is a measure of cardiac performance that incorporates both pressure and flow components. Prior studies have shown that cardiac power predicts outcomes in patients with reduced left ventricular […]

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Comparison of Outcomes of Beta-Blocker Therapy after Acute Myocardial Infarction in Patients without Heart Failure or Left Ventricular Systolic Dysfunction (From the Acute Coronary Syndromes Israeli Survey [ACSIS]).

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The contemporary benefit of routine beta-blocker therapy following myocardial infraction in the absence of heart failure or left ventricular systolic dysfunction (LVSD) is unclear. We investigated the impact of beta-blockers […]

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Prognostic Value of Pre-operative Atrial Fibrillation in Patients with Secondary Mitral Regurgitation Undergoing MitraClip Implantation.

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Limited data are available regarding the independent prognostic role of pre-operative AF after transcatheter mitral valve repair with MitraClip. We sought to evaluate the impact of pre-operative atrial fibrillation (AF) […]

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Alternative Echocardiographic Algorithm for Left Ventricular Filling Pressure in Patients with Heart Failure with Preserved Ejection Fraction.

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The American Society of Echocardiography / the European Association of Cardiovascular Imaging recommend a conventional algorithm for estimating left ventricular (LV) filling pressure in heart failure. However, several patients are […]

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Influence of Chronic Obstructive Pulmonary Disease on Atrial Mechanics by Speckle Tracking Echocardiography in Patients with Atrial Fibrillation.

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The present study aimed to examine differences in left- and right atrial characteristics between atrial fibrillation (AF) patients with and without chronic obstructive pulmonary disease (COPD). For this, 420 patients […]

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Systolic Blood Pressure and Risk for Ventricular Arrhythmia in Patients with an Implantable Cardioverter Defibrillator.

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Low systolic blood pressure (SBP) was previously suggested to be a marker for heart failure and mortality in patients with low left ventricular (LV) ejection fraction (EF). We aimed to […]

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N-terminal pro-brain natriuretic peptide and sudden cardiac death in hypertrophic cardiomyopathy.

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Elevated levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) are associated with heart failure-related death in hypertrophic cardiomyopathy (HCM), but the relationship between NT-proBNP level and sudden cardiac death (SCD) in […]

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Greater admissions, mortality and cost of heart failure in adults with congenital heart disease.

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Limited contemporary data exist regarding outcomes and resource use among adults with congenital heart disease and heart failure (ACHD-HF). This study compared outcomes, emergency department (ED) and hospital resource use, […]

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Low-density lipoprotein cholesterol reduction and statin intensity in myocardial infarction patients and major adverse outcomes: a Swedish nationwide cohort study.

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Clinical trials have demonstrated that a reduction in low-density lipoprotein cholesterol (LDL-C) reduces cardiovascular (CV) events. This has, however, not yet been shown in a real-world setting. We aimed to […]

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Effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction, with and without type 2 diabetes.

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The EMPERIAL (Effect of EMPagliflozin on ExeRcise ability and HF symptoms In patients with chronic heArt faiLure) trials evaluated the effects of empagliflozin on exercise ability and patient-reported outcomes in […]

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Impact of Arrhythmias on Hospitalizations in Patients with Cardiac Amyloidosis.

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Cardiac involvement in amyloidosis is associated with a poor prognosis. Data on the burden of arrhythmias in patients with cardiac amyloidosis (CA) during hospitalization is lacking. We identified the burden […]

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Diagnostic and Prognostic Value of Several Color Doppler Jet Grading Methods in Patients with Mitral Regurgitation.

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Color Doppler is a widely used ultrasound imaging method for assessing mitral regurgitation (MR) in clinical practice. Nevertheless, color Doppler-based grading of the MR jet has been rarely considered in […]

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Prognostic value of automated longitudinal strain measurements in asymptomatic aortic stenosis.

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Two-dimensional (2D) longitudinal strain (LS) predicts cardiac events in aortic stenosis (AS). However, it requires manual editing, which affects its accuracy and reliability. We investigated whether left ventricular (LV), left […]

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Vegetarians, fish, poultry, and meat-eaters: who has higher risk of cardiovascular disease incidence and mortality? A prospective study from UK Biobank.

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To compare the incidence and mortality risk for cardiovascular diseases (CVD) [CVD and also ischaemic heart disease (IHD), myocardial infarction (MI), stroke, and heart failure (HF)] among people with different […]

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Lipid Profile and Subsequent Cardiovascular Disease among Adults Aged < 50 Years.

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Epidemiological evidence on the relationship between lipid profile and cardiovascular disease (CVD) events in young adults remains insufficient. Thus, we sought to explore the association of lipid profile with subsequent […]

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The risk of cardiac events in patients receiving immune checkpoint inhibitors: a nationwide Danish study.

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The study aimed to estimate the risk of cardiac events in immune checkpoint inhibitor (ICI)-treated patients with lung cancer or malignant melanoma.The study included consecutive patients with lung cancer or […]

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Meta-Analysis of the Usefulness of Catheter Ablation of Atrial Fibrillation in Patients with Heart Failure with Preserved Ejection Fraction.

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Catheter ablation improves clinical outcomes in atrial fibrillation (AF) patients with heart failure (HF) with reduced ejection fraction (HFrEF). However, the role of catheter ablation in HF with a preserved […]

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Outcomes with Ultrafiltration among Hospitalized Patients with Acute Heart Failure (From the National Inpatient Sample).

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Acute heart failure (HF) management is a complex and often involves a delicate balance of both cardiac and renal systems. While pharmacologic diuresis is a mainstay of the pharmacologic management […]

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Treatment of Patients with Recurrent Coronary In-Stent Restenosis with Failed Intravascular Brachytherapy.

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Intravascular brachytherapy (VBT) is an effective and safe treatment option for recurrent drug-eluting stent (DES) in-stent restenosis (ISR). However, the optimal therapy for patients with failed VBT is not well-defined. […]

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